Industrial Emodin (CAS 482-44-0) | GMP Certified Production
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Bulk Emodin Manufacturer | 98% Crystalline Powder | AIHerba®

  1. Product Name: Emodin Powder | Industrial Bulk Supply

  2. Assay (HPLC): ≥98.0% (Certified Active Anthraquinone Isolate)

  3. Appearance: Orange Fine Crystalline Powder (Uniform Particle Size)

  4. CAS No.: 482-44-0

  5. Solubility: Soluble in Ethanol and DMSO; Practically Insoluble in Water

  6. Stability: High Thermal Stability; Light-Sensitive (Store in Amber Packaging)

  7. Lead Time: 3–7 Working Days (Global Bulk Stock)

  8. Packaging: 25kg Standard Drum / 1kg Sample Available

  9. Compliance: GMP Certified / Full Batch COA & TDS Provided

  10. Application: Pharmaceutical Intermediates / Specialized Cosmeceuticals / OEM/ODM

Bulk Supply & Technical Advisory
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01. Emodin Bulk Supplier — Procurement Summary

Manufacturer: AIHerba®
Grade: Pharma / Nutraceutical / Cosmetic
Supply Form: Crystalline Powder (95% / 98%)
MOQ: 1kg (R&D) / 25kg (Bulk)
Lead Time: 3–5 Business Days
COA: Batch-Specific NMR/HPLC Available
Packaging: 25kg Fiber Drum / Vacuum Foil
Export: Global B2B DDP/CIF Ready

02. Manufacturer & Quality Assurance Platform

AIHerba® Industrial Infrastructure

Operated by Shaanxi Zhonghong Investment Technology Co., Ltd., our facility integrates high-vacuum molecular distillation and multi-stage crystallization. We provide pharmaceutical-grade transparency with a dedicated QMS (Quality Management System) optimized for international audits.

GMP Manufacturing
Batch Traceability
Raw Material Control
OEM/ODM Support

03. Emodin Identity Profile

Parameter Scientific Specification
Chemical Name 1,3,8-Trihydroxy-6-methylanthraquinone
CAS Number 482-44-0
Molecular Weight 270.24 g/mol
Source Rheum palmatum / Polygonum cuspidatum
Appearance Orange Fine Crystalline Powder
Grade Pharma / Nutraceutical / R&D Grade

04. Technical Specification & Release Standard

PURITY (HPLC)

≥ 98.0%

MELTING POINT

255°C – 258°C

HEAVY METALS

≤ 10 ppm

RESIDUAL SOLVENT

Ethanol < 0.5%

LOSS ON DRYING

≤ 1.0%

PARTICLE SIZE

80 – 100 Mesh

MICROBIAL COUNT

≤ 1000 cfu/g

SHELF LIFE

24 Months

05. Analytical Verification & Scientific Fingerprint

Our laboratory ensures absolute molecular integrity through standardized phytochemical fingerprinting. Every industrial batch must conform to the following instrumental benchmarks:

HPLC-DAD
Purity & Assay
HS-GC-MS
Residual Solvents
ICP-MS
Heavy Metals
FT-IR / NMR
Structural Confirm

* Illustrative Technical Simulation: Typical batch release profile using validated pharmacopeia methods.

06. Batch Release & Quality Control System

01 Raw Material Inspection
02 Extraction & Distillation
03 Laboratory Testing
04 Batch Release (QA)
05 Document Archive

07. Manufacturing Process & Engineering Control

The AIHerba industrial process for Emodin isolation begins with the selection of high-yield Polygonum cuspidatum roots. We utilize low-temperature solvent extraction followed by column chromatography to separate emodin from physcion and other anthraquinone derivatives. The final stage involves re-crystallization in a cleanroom environment to achieve ≥98% purity while maintaining consistent crystalline morphology for downstream formulation.

08. Molecular Structure & Functional Characteristics

Emodin (1,3,8-trihydroxy-6-methylanthraquinone) is a natural anthraquinone derivative. Its industrial efficacy is rooted in its planar aromatic structure, which allows for specific binding in cellular signaling assays. Key functional characteristics include high thermal stability (Melting point >250°C) and specific molecular habit that supports its use as a precursor in pharmaceutical synthesis and a targeted active in high-end dermaceuticals.

09. Industrial Application Compatibility

Cosmetic Formulation

Functional properties in specialized skin-lightening and anti-inflammatory topical systems.

Nutraceutical Research

Industrial supply for metabolic health supplement research and cellular longevity studies.

Pharmaceutical Intermediate

High-purity crystalline precursor for advanced synthetic drug development and oncology research.

10. Formulation Development Guide

Solubility Profile

Practically insoluble in water. Soluble in Ethanol, DMSO, and alkaline solutions. For aqueous formulations, use of micellar delivery or liposomal carriers is recommended.

pH Compatibility

Stable under acidic and neutral conditions. In highly alkaline environments (pH > 10), the color shifts to deep red due to phenolic deprotonation.

11. Stability & Transport Engineering

Risk: Light Sensitivity
Emodin exhibits photodegradation over long-term exposure to UV radiation.
Solution: Primary packaging in light-resistant amber bags + Secondary fiber drum.
Engineering: Moisture Control
Hygroscopic adsorption can affect crystalline flowability on automated lines.
Solution: Vacuum-sealed induction liners with desiccant packs for bulk export.

16. Market Benchmark Comparison

Metric Generic Market Supply AIHerba® Industrial Grade
Assay Precision Variable (±3%) Batch Standard ≥ 98.0%
Residual Solvents Standard Check ICH Q3C Compliant (ND Class 1)
NMR Identification None Validated 1H/13C NMR spectra
Technical Support Basic Data Full Dossier & Engineering Consultation

17. Technical Procurement FAQ

What is the lead time for a 500kg industrial batch?
Standard lead time for existing inventory is 3-5 days. For custom manufacturing campaigns, lead time is 14-21 days including final analytical release.
How do you ensure the absence of Emodin-8-glucoside?
Our high-vacuum purification specifically separates the aglycone (Emodin) from its glycoside precursors, verified via HPLC to ≤ 0.5%.
Is your Emodin compliant with European REACH regulations?
Yes, AIHerba provides necessary technical data and SDS documentation for REACH registration and EU market entry.
Can you provide custom particle sizes for capsule filling?
Yes, we offer micronization services to achieve D90 < 20µm for enhanced bioavailability or 80-mesh for standard tableting.

18. AIHerba Industrial Quality Commitment

✓ GMP Manufacturing
✓ Batch Traceability
✓ Analytical Release
✓ Technical Dossier
✓ OEM Support
✓ Global Export


Bulk Supply & Technical Advisory
🛡️
GMP Certified
🔬
HPLC Lab Tested
🌍
Global Logistics
📦
Free Samples
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