Eurycoma Longifolia Extract

Eurycoma Longifolia Extract: The Ultimate Guide to Malaysia’s “Natural Testosterone Booster”

1. What is Eurycoma Longifolia Extract?

Eurycoma Longifolia Extract, derived from the roots of the Eurycoma longifolia plant, is a premier adaptogen revered as “Malaysian Ginseng” or “Tongkat Ali” (Malay for “Ali’s Walking Stick”). This evergreen tree thrives in Southeast Asia’s acidic, sandy rainforest soils and features a distinctive unbranched trunk (4–18m tall) with umbrella-like leaf crowns 16. For centuries, indigenous communities have used its bitter roots to combat fatigue, enhance virility, and treat malaria 5. Modern science validates its bioactivity, primarily attributed to quassinoids (eurycomanone) and canthin-6-one alkaloids 18.

2. Source, Chemical Properties & Technical Specifications

Botanical Sources & Extraction

• Primary Source: Roots (highest bioactive concentration); leaves/stems secondary 14.

• Extraction Methods:

  • Water/ethanol solvent extraction → macroporous resin purification

  • Supercritical CO₂ for high-purity eurycomanone isolation (>10%) 710.

Key Phytochemical: Eurycomanone

3. Health Benefits, Optimal Dosage & Safety

Therapeutic Advantages

• Testosterone Enhancement: Increases free testosterone by 440% via inhibition of SHBG (sex hormone-binding globulin) and aromatase 510.

• Fertility Improvement: Boosts sperm motility by 44% and concentration by 62% in idiopathic infertile men 58.

• Stress Reduction: Lowers cortisol levels by 16–32% in moderately stressed subjects 58.

• Anticancer Activity: Induces apoptosis in HepG2 liver cancer cells via p53 activation 1.

• Ergogenic Effects: Increases muscle strength by 5–15% in athletes 5.

Dosage Recommendations

• Standardized Extracts: 200–400 mg/day of 100:1 extract (delivering 1–4 mg eurycomanone) 58.

• Therapeutic Use: Up to 600 mg/day for ≤12 weeks (clinical supervision advised) 8.

• Cycling Protocol: 5 days on, 2 days off to prevent receptor desensitization.

Highest-Potency Products

• 100:1–200:1 Root Extracts: Concentrated to 5–10% eurycomanone 710.

Safety & Precautions

• Contraindications: Prostate/breast cancer, pregnancy, hypertension (may interact with propranolol) 8.

• Side Effects: Mild insomnia, gastric discomfort (dose-dependent) 5.

• Heavy Metal Risk: Source from GMP-certified suppliers to avoid lead/mercury contamination 8.

4. Company Introduction: Shaanxi Zhonghong Investment Technology Co., Ltd.

A 28-year industry pioneer specializing in premium plant extracts for nutraceutical, pharmaceutical, and cosmetic applications. Leverages proprietary purification tech to deliver eurycomanone-rich Eurycoma extracts exceeding pharmacopeial standards.

Core Capabilities:

• Patent-Protected Extraction: 20+ patents covering chromatographic isolation of quassinoids.

• Analytical Rigor: HPLC-PDA-ELSD, 800MHz NMR, ICP-MS ensuring >99.5% purity.

• Global Compliance: ISO 9001, FDA-GMP, EFSA, JECFA certifications.

• Supply Chain Excellence: Cold-chain logistics across 80+ countries.

5. Product Specifications: Premium Eurycoma Extract QC Standards

Pesticide Residues

Heavy Metals

Microbiological Parameters

6. Production Workflow: From Root to Pharma-Grade Extract

1. Sustainable Harvesting: 5+ year-old roots sourced from Malaysia/Indonesia.

2. Primary Extraction: Ethanol/water (60:40) dynamic maceration (50°C, 8h).

3. Concentration: Vacuum evaporation → 20% solids.

4. Purification: AB-8 macroporous resin → preparative HPLC.

5. Standardization: Eurycomanone adjustment to 5–10%.

6. Drying: Spray-drying → 80-mesh powder 110.

7. Applications Across Industries

• Nutraceuticals: Testosterone boosters, stress-relief capsules, athletic performance formulas.

• Pharmaceuticals: Adjuvant therapy for male infertility and hormone-deficient osteoporosis.

• Cosmeceuticals: Anti-aging serums (upregulates collagen synthesis).

• Functional Foods: Energy bars, fortified beverages 49.

8. Quality Control: Triple-Phase Verification

1. Identity Confirmation: FT-IR spectrum match (3,400 cm⁻¹ O-H, 1,660 cm⁻¹ C=O).

2. Purity Quantification: HPLC-UV at 254 nm (eurycomanone ≥10%).

3. Contaminant Screening: ICP-MS for heavy metals; GC-MS/MS for 426 pesticides.

4. Stability: 24-month shelf-life under 25°C/60% RH 710.

9. Research Frontiers & Challenges

• Mechanistic Insights:

  • Androgen receptor allosteric modulation

  • AMPK/PGC-1α mitochondrial biogenesis

• Clinical Gaps: Long-term safety data (>1 year); dosing optimization for women.

• Sustainability: Tissue culture propagation to protect wild populations 15.

10. FAQ: Expert Answers

Q: Does Eurycoma increase estrogen?
A: No. Eurycomanone inhibits aromatase, reducing testosterone-to-estrogen conversion 8.

Q: Safe for hypertensive patients?
A: Contraindicated with blood pressure medications (e.g., propranolol) due to interaction risks 8.

Q: Optimal consumption time?
A: Morning with fatty meals (enhances quassinoid absorption).

Q: When to expect results?
A: Libido enhancement in 5–7 days; testosterone optimization requires 4–12 weeks 5.

Where to Buy Pharmaceutical-Grade Extract

🔬 Direct Order from Shaanxi Zhonghong:

• Email: liaodaohai@gmail.com

• Website: aiherba.com

Conclusion

Eurycoma Longifolia Extract exemplifies nature’s answer to hormonal balance—with robust evidence supporting its roles in vitality, stress resilience, and metabolic health. For brands prioritizing safety and efficacy, Shaanxi Zhonghong delivers unmatched technical rigor: ISO-certified extraction, batch-specific NMR validation, and global logistics.

Unlock Peak Vitality—Request Your Certificate of Analysis Today!

References:

1. ChemicalBook. (2023). Eurycoma Longifolia Extract Properties & Applications 1.

2. Ismail et al. (2012). Asian Journal of Andrology. Fertility enhancement study 5.

3. Talbott et al. (2013). Journal of the International Society of Sports Nutrition. Cortisol reduction data 58.

4. HealthyPig. (2024). Clinical Benefits & Safety Profile 5.

5. Examine.com. (2023). Mechanistic Analysis & Dosage Guidelines 8.

6. Hubei Health Pig. (2024). Bioactive Compounds & Traditional Uses 5.