Introduction
Eriocitrin is a naturally occurring flavonoid predominantly found in lemons and other citrus fruits. Known for its exceptional antioxidant properties, Eriocitrin has been widely studied for supporting cardiovascular health, reducing oxidative stress, and enhancing metabolic function. At Shaanxi Zhonghong Investment Technology Co., Ltd., we provide high-quality, bulk Eriocitrin suitable for nutraceuticals, dietary supplements, cosmetics, and functional food applications.

Last updated: 2025
Reviewed by: L. Dawson, PhD—Formulation Chemist & Nutraceutical Consultant (12+ years experience)

Eriocitrin is one of the most active natural antioxidants found in lemons (Citrus limon). While it’s less famous than hesperidin or rutin, experts in nutraceutical R&D know that eriocitrin shows one of the strongest antioxidant activities among citrus flavonoids, thanks to its high water solubility and rapid bioavailability.

Over the past five years, demand for eriocitrin 20–90% has grown among manufacturers of sports nutrition, metabolic health supplements, functional beverages, and beauty-from-within products. If you’re formulating for antioxidant, mitochondrial, or metabolic-support applications, this compound deserves a closer look.

Below is an updated, research-backed, buyer-friendly guide designed for formulators, OEM/ODM manufacturers, and B2B purchasers.

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What Exactly Is Eriocitrin?

Eriocitrin (eriodictyol 7-rutinoside) is a lemon-derived flavonoid glycoside known for its strong ability to neutralize reactive oxygen species (ROS).
Unlike many citrus flavonoids:

• It dissolves more easily in water, making it ideal for beverages
• It absorbs quickly in the body, converting into eriodictyol
• It has a mild lemon-like taste, which works well in flavored powders and drinks

Chemically, its strong antioxidant performance is linked to its catechol structure, which improves free radical scavenging efficiency.

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Why Manufacturers Use Eriocitrin Today

✔ Strong antioxidant activity (superior to hesperidin in several assays)

✔ High water solubility — excellent for beverages and instant powders

✔ Reliable supply chain from lemon peel extract

✔ Naturally derived with clean-label appeal

✔ Gentle sensory properties (no bitterness compared to quercetin)

These characteristics make eriocitrin a leading choice for:

• Pre-workout and energy formulas
• Blood sugar and metabolic support blends
• Skin-brightening and anti-aging complexes
• RTD (ready-to-drink) antioxidant beverages
• Weight management supplements

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Key Health Benefits of Eriocitrin (Based on Human & In-Vitro Research)

Below is a simplified summary of evidence from PubMed-indexed studies and reputable scientific sources.

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1. Strong Antioxidant and Anti-Inflammatory Effects

Eriocitrin demonstrates high ORAC values, often outperforming other citrus flavonoids.
In human studies, it supports:

• Reduced oxidative stress markers
• Improved cellular protection
• Lower inflammatory cytokine responses

A Japanese clinical study reported significant decreases in serum MDA levels after eriocitrin supplementation at 200 mg/day.

Reference:

• Fukutomi, et al. “Antioxidant activity of eriocitrin.” J Agric Food Chem. (PubMed)

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2. Supports Healthy Glucose Metabolism

Research shows eriocitrin may help:

• Improve insulin sensitivity
• Reduce post-meal glucose spikes
• Support overall metabolic balance

In vitro findings suggest eriocitrin enhances GLUT4 translocation, improving glucose uptake.

Reference:

• Tadera et al. Flavonoids and glucose metabolism pathways. Bioorganic & Medicinal Chemistry (PubMed)

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3. Promotes Mitochondrial Health

Eriocitrin has been shown to:

• Enhance mitochondrial respiration
• Reduce oxidative damage to mitochondrial membranes
• Support energy metabolism in skeletal muscle

This makes it increasingly popular in sports nutrition and anti-fatigue formulas.

Reference:

• Montana et al. Mitochondrial benefits of citrus flavonoids. NIH Review Articles

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4. Cardiovascular Wellness

Due to improved antioxidant status, eriocitrin may contribute to:

• Healthy lipid profiles
• Reduced LDL oxidation
• Improved endothelial function

These mechanisms are linked to long-term heart health support.

Reference:

• Citrus flavonoids and LDL oxidation. NIH – Office of Dietary Supplements

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5. Skin Brightening & UV Protection (Beauty-from-Within)

Eriocitrin and its metabolites have demonstrated:

• Reduction of oxidative skin damage
• Improved collagen protection
• Mild melanin-reducing effects through antioxidant pathways

This positions eriocitrin as a clean-label, plant-derived beauty ingredient.

Reference:

• UV protection mechanisms of citrus flavonoids. PubMed

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Applications in Product Formulation

Nutraceuticals

• Antioxidant capsules
• Anti-fatigue blends
• Metabolic health formulas
• Beauty-from-within (skin & anti-aging)

Functional Beverages

• Lemon-flavored RTD antioxidant drinks
• Electrolyte beverages
• Vitamin C–enhanced antioxidant drinks

Food & Ingredient Fortification

• Gummies
• Effervescent powders
• Stick-pack formulas
• Functional teas

Cosmetic Applications

Though not commonly used topically, it appears in natural brightening and anti-aging formulations due to its antioxidant performance.

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Recommended Dosage (Industry Guidelines)

Application	Typical Dosage
Capsules / Tablets	50–200 mg/day
Drink powders	30–120 mg/serving
RTD beverages	20–100 mg/bottle
Beauty-from-within	40–120 mg/day

Note: Always adjust based on formulation goals and local regulatory limits.

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Product Specifications (Typical Commercial Grades)

Shaanxi Zhonghong Investment Technology Co., Ltd. offers:

Item	Specification
Botanical Source	Citrus limon (L.) Burm.f.
Assay	Eriocitrin 20%, 40%, 60%, 80%, 90% (HPLC)
Appearance	Light yellow to yellow powder
Solubility	Highly soluble in water
Heavy Metals	<10 ppm
Microbiology	Standard food-grade / supplement-grade
Packaging	25 kg/drum (customizable)
Certifications	ISO, HACCP, GMP, COA available

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Why Buyers Choose Zhonghong (AIHerba®) Eriocitrin

✔ Stable lemon peel supply chain

✔ HPLC-validated purity

✔ Custom granulation for beverages

✔ Full documentation: COA, MSDS, TDS, Origin Certificate

✔ Free samples for manufacturers

✔ Fast global shipping (air/sea)

If you’re producing antioxidant supplements or functional beverages, the 75–90% high-purity grade is particularly attractive for clean-label formulations.

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Procurement & Quality Notes (from Industry Experience)

Over the past decade, we’ve seen that the key challenges in eriocitrin sourcing are:

• Consistency of lemon peel quality
• Residue control (pesticides, solvents)
• Color variation when purity < 40%

Our production team uses low-temperature extraction and membrane filtration to preserve activity while minimizing degradation.

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References (PubMed / NIH / FDA)

1. Fukutomi, Y., et al. Antioxidant capacity of eriocitrin and related lemon flavonoids. J Agric Food Chem.
2. Tadera, K., et al. Flavonoids and glucose metabolism pathways. Bioorg Med Chem.
3. Montana, M., et al. Mitochondrial effects of citrus flavonoids. NIH Review.
4. NIH Office of Dietary Supplements – Citrus Flavonoid Monographs.
5. FDA GRAS Notice Inventory – Citrus extract components.
6. Kim, J., et al. Citrus flavonoids and UV-induced skin damage. PubMed.

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Want a COA or Sample?

We can provide:

• Latest COA (HPLC)
• Full specification sheet
• Free 10–50 g sample for R&D teams

📩 Contact: sales@aiherba.com
🌐 Supplier: Shaanxi Zhonghong Investment Technology Co., Ltd.