These 5 nutritional supplements have the best anti-aging effect and make women always 18 years old

1. Urolithin A: Nature’s anti-aging secret

Urolithin A, a natural metabolite that has received widespread attention in the field of anti-aging research in recent years, has become the focus due to its unique physiological activity.
Nutritionists at Nova Southeastern University in the United States have found that urolithin A can significantly slow down the aging process, which provides a new perspective for us to understand the role of urolithin A in maintaining the health of organisms.
Urolithin A helps cells recycle and renew damaged mitochondria by promoting mitochondrial autophagy, a process that is essential for maintaining the normal function of cells.
Mitochondria are known as the “energy factory” of cells, and their health status is directly related to the vitality of cells and the aging rate of organisms.
However, urolithin A does not come directly from the diet, but is the product of compounds in certain foods that are metabolized by intestinal microorganisms.
This means that by consuming a moderate amount of foods rich in ellagic acid and ellagitannins, such as nuts, pomegranates, grapes and other berries, we can indirectly increase the level of urolithin A in the body, thereby exerting an anti-aging effect.

2. Nicotinamide mononucleotide (NMN): A regenerative fountain of cellular energy

Another eye-catching study focuses on nicotinamide mononucleotide (NMN), a substance closely related to human energy metabolism.
Studies have shown that NMN is a precursor of NAD+, which is an indispensable coenzyme in cellular energy conversion, and its reduced level is closely related to the aging process.
A study published in the journal Cell Metabolism by a research team from the University of Oslo in Norway (December 2016) showed that long-term supplementation with NMN can slow down age-related physiological decline in mice.
This study not only demonstrates the potential of NMN in increasing NAD+ levels and delaying the aging process, but also provides an important theoretical basis for human anti-aging research.
It is worth mentioning that although NMN has attracted much attention as a potential anti-aging supplement, the recent decision of the US Food and Drug Administration (FDA) restricts its sale as a dietary supplement, mainly because NMN is being further studied as a new drug candidate.

3. Spermidine: A natural polyamine that prolongs life

When exploring substances in nature that are beneficial to human health, spermidine stands out and becomes another highlight of anti-aging research.
Spermidine is a polyamine present in the human body and a variety of foods. In recent years, it has attracted widespread attention from scientists for its potential to prolong life and improve health.
A study conducted by a research team from Kyoto Prefectural University of Medicine in Japan revealed that the level of spermidine is closely related to the healthy life span of an individual.
In the normal aging process, the concentration of natural spermidine in the human body gradually decreases, but this phenomenon is not observed in centenarians, who have relatively high spermidine concentrations.
This property of spermidine, especially its ability to promote autophagy, is essential for maintaining cell function and delaying the aging process. Autophagy is a way for cells to clean up damaged components, which is important for maintaining cell health and preventing the development of various diseases.
Therefore, increasing the level of spermidine in the body through food or supplements may become an effective anti-aging strategy.
Foods rich in spermidine include whole-wheat products, kelp, shiitake mushrooms, nuts, bracken and purslane. A reasonable diet can help maintain an appropriate level of spermidine in the body.
Fisetin: A natural anti-aging agent targeting senescent cells
The accumulation of senescent cells is considered a key factor in the aging process. These cells lose their ability to divide, but do not die. Instead, they begin to actively secrete a variety of pro-inflammatory and tissue-destructive factors, causing damage to surrounding cells and tissues.

4. Fisetin, as a naturally occurring anti-aging compound, has attracted widespread attention in the scientific community.

Geneticists from Tianjin Medical University have found that fisetin can significantly affect the aging process and improve overall health by reducing the accumulation of these dysfunctional cells.
This discovery not only provides us with a new anti-aging strategy, but also provides a scientific basis for further exploring the role of fisetin in human health.
Fisetin is widely present in a variety of foods, including but not limited to strawberries, apples, mangoes, persimmons, kiwis, grapes, tomatoes, onions, cucumbers, etc.
The regular intake of these foods can not only enrich our dietary taste, but also provide natural anti-aging support. In addition, the anti-inflammatory and antioxidant properties of fisetin have also made it the focus of researchers and health enthusiasts.

5. Curcumin: Dual protection of anti-inflammatory and antioxidant

Curcumin, the active compound from turmeric, has attracted much attention for its powerful anti-inflammatory and antioxidant properties and is regarded as an anti-aging treasure in nature.
Research conducted by experimental biologists from the Polish Academy of Sciences found that curcumin can not only effectively reduce the symptoms of aging, but also delay the progression of age-related diseases involving senescent cells, thus showing great potential in extending life.
These research results not only reveal the key role of curcumin in maintaining cell health and resisting the aging process, but also provide a scientific basis for adding curcumin to the daily diet.
The anti-inflammatory effect of curcumin is particularly important for anti-aging, because chronic inflammation is considered to be a key driver of many age-related diseases, including cardiovascular disease, diabetes, cancer and Alzheimer’s disease.
By reducing inflammatory responses, curcumin helps reduce the risk of these diseases and thus prolong healthy life.
In addition to turmeric, curcumin is also found in foods such as ginger, garlic, onion, black pepper, mustard and curry, and daily consumption of these foods can be an easy way to increase your curcumin intake.

References

1. Yousefzadeh, M. J., et al. (2018). EBioMedicine, 36, 18–28.
2. Khan, N., et al. (2013). Antioxidants & Redox Signaling, 19(2), 151–162.
3. Zhou, C., et al. (2023). European Journal of Medical Research, 28(1), 297.
4. Zhu, Y., et al. (2017). Aging, 9(3), 955–963.
5. Qualia Life. (2023). “Fisetin Formulation.” Retrieved from qualialife.com.