Urolithin A Bulk Supplier: High-Purity Mitophagy Ingredient
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99% Pure Urolithin A | Trusted B2B Manufacturer AIHerba®

  1. Product Name: Urolithin A | Industrial Bulk Supply

  2. Assay (HPLC): ≥ 99.0% (Certified High-Purity Metabolite)

  3. Appearance: Off-White to Light Yellow Powder (Uniform Particle Size)

  4. CAS No.: 1143-70-0

  5. Solubility: Lipophilic (Soluble in DMSO/Ethanol; Customizable for Micellar Formulations)

  6. Stability: High Thermostability; Optimal Storage in Cool, Dry Environment

  7. Lead Time: 3–7 Working Days (Global Bulk Stock Ready for Air-Freight)

  8. Packaging: 25kg Industrial Standard Drum / 1kg Pilot Evaluation Kit

  9. Compliance: GMP Certified Facility / Full Batch-Specific COA, MSDS & NMR Provided

  10. Application: Longevity Supplements, Anti-Aging Skincare, Mitophagy-Targeted Nutraceuticals

Bulk Supply & Technical Advisory
🛡️
GMP Certified
🔬
HPLC Lab Tested
🌍
Global Logistics
📦
Free Samples

01. Urolithin A Bulk Supplier — Procurement Summary

Manufacturer: AIHerba®
Grade: Pharma / Nutraceutical / R&D
Supply Form: Ultra-Pure Crystalline Powder
MOQ: 1kg (R&D) / 25kg (Production)
Lead Time: 3–5 Business Days
COA: 1H-NMR & HPLC Verified
Packaging: 25kg Sealed Fiber Drum
Export: Global DDP/CIF Ready

02. Manufacturer & Quality Assurance Platform

AIHerba® Industrial Infrastructure

Operated by Shaanxi Zhonghong Investment Technology Co., Ltd., we utilize a vertically integrated synthesis platform. Our facility is cGMP/FSMA compliant, ensuring 100% batch-to-batch consistency and full traceability from precursor to final crystalline isolate.

29-Year Manufacturing
FSMA / GMP Site
Batch NMR Release
OEM Particle Engineering

03. Urolithin A Identity Profile

Urolithin A aiherba
Urolithin A aiherba
Parameter Industrial Specification
Chemical Name 3,8-Dihydroxy-6H-dibenzo[b,d]pyran-6-one
CAS Number 1143-70-0
Molecular Formula C13H8O4
Molecular Weight 228.20 g/mol
Source Biomimetic Total Synthesis (Non-Animal Origin)
Appearance Beige to Yellow Crystalline Powder

04. Technical Specification & Release Standard

PURITY (HPLC)

≥ 99.5% (Typical 99.66%)

RESIDUAL TOLUENE

Non-Detected (ND)

WATER CONTENT

≤ 0.5% (KF Method)

HEAVY METALS (TOTAL)

≤ 10 ppm (Prop 65 OK)

MELTING POINT

338°C – 341°C

MICROBIAL COUNT

≤ 1000 cfu/g

PARTICLE SIZE

80 Mesh / 200 Mesh

SHELF LIFE

36 Months

05. Analytical Verification & Scientific Fingerprint

AIHerba® eliminates structural uncertainty. We don’t just provide a COA; we provide the raw spectral evidence for every industrial lot.

HPLC-DAD
Purity Verification
1H-NMR (400MHz)
Molecular Fingerprint
LC-MS/MS
Impurity Profiling
HS-GC-FID
Solvent Control

* Illustrative Technical Simulation: Every batch is released against a validated reference standard.

06. Batch Release & Quality Control System

01 Raw Material Inspection
02 Toluene-Free Synthesis
03 Double Recrystallization
04 Spectral Verification
05 Batch Release (QA)

07. Manufacturing Process & Engineering Control

AIHerba utilizes a Green Chemistry Protocol for Urolithin A manufacturing. Unlike standard methods that use Toluene as a solvent (ICH Class 2), our process utilizes anhydrous ethanol and ethyl acetate systems. The process includes multi-stage Cryogenic Jet-Milling to control particle morphology, followed by high-vacuum sifting to ensure zero clumping for high-speed automated encapsulation lines.

08. Molecular Structure & Functional Characteristics

Urolithin A is a unique microflora-derived metabolite. Its industrial value lies in its Mitochondrial Activation property through the induction of Mitophagy. Functionally, AIHerba® Urolithin A mimics the endogenous molecule with 100% bio-identity, providing a standardized dosing solution that bypasses individual variations in gut microbiome production capability.

09. Industrial Application Compatibility

Nutraceutical Longevity

Mitochondrial health support in capsules, tablets, and liposomal powder blends.

Sports Nutrition

Functional property for muscle endurance and post-exercise recovery formulations.

Medical Nutrition

API-grade intermediate for clinical research in age-related metabolic decline.

10. Formulation Development Guide (Solving the Flowability Challenge)

Flowability Optimization

Standard UA is naturally electrostatic. AIHerba provides a Granular Grade (40-80 mesh) specifically for high-speed automated lines. We recommend pairing with 0.5% fumed silica and 15% MCC for optimal tableting weight precision.

Solubility Strategy

Practically insoluble in water. For liquid formulations, use MCT Oil suspensions or Beta-Cyclodextrin complexation to enhance dispersion and stability.

11. Stability & Transport Engineering

Thermal Stability
Extremely robust under thermal stress (MP 340°C). 24-month accelerated stability data shows <0.2% assay variation.
Moisture Sensitivity
AIHerba UA is non-hygroscopic. Vacuum-sealed foil liners prevent oxidative darkening during cross-ocean shipping.

16. Market Benchmark Comparison

Metric Standard Trader Supply AIHerba® Industrial Grade
Assay (HPLC) 98.0% – 99.0% ≥ 99.5% (Pharma Standard)
Residual Toluene ~500 ppm Non-Detected (ND)
Structural Verification None / HPLC only Full Batch 1H-NMR Release
Flowability Clumping / Electrostatic Custom Engineered Grain Size

17. Technical Procurement FAQ

Q1: Why is Toluene-free synthesis critical for Urolithin A?
Toluene is an ICH Class 2 solvent with nervous system toxicity. While the limit is 890ppm, Tier-1 brands demand ND (Non-Detected) for US “Clean Label” compliance. AIHerba uses an alternative ethanol-based system to ensure safety.
Q2: What is the lead time for a 500kg industrial order?
Standard inventory of 500kg-1000kg is maintained at our Shaanxi hub. Lead time is 3-5 days from order to export documentation release.
Q3: How do you verify you have Urolithin A and not an isomer?
Standard HPLC can confuse UA with other dibenzo-pyranones. We release every batch with 400MHz 1H-NMR spectra to confirm the exact hydrogen shift positions, guaranteeing molecular identity.
Q4: Is the material compatible with California Prop 65?
Yes. Our heavy metal limits (Pb < 0.1ppm, As < 0.2ppm) are significantly stricter than USP standards, ensuring full compliance for California retail markets.

18. AIHerba Industrial Quality Commitment

✓ GMP Manufacturing
✓ Batch NMR Release
✓ Toluene-Free Certified
✓ Full Technical Dossier
✓ Global DDP Export

Bulk Supply & Technical Advisory
🛡️
GMP Certified
🔬
HPLC Lab Tested
🌍
Global Logistics
📦
Free Samples
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