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Yohimbine Extract Wholesale | Factory-Direct Botanical Extract Manufacturer

1. English Name: Yohimbine Extract

2. Specification: Available in multiple grades depending on formulation needs:

  • ≥ 98% Yohimbine (HPLC)

  • Optional 5% Anthocyanins

  • Water-soluble and oil-soluble versions available for flexible application

3. Appearance: A yellowish-white crystalline solid with a mild, characteristic cocoa-like aroma.

4. CAS No.:146-48-5 (Yohimbine)
65-19-0 (Yohimbine HCL)
(Use according to product type.)

5. Lead Time:3–7 working days, depending on order size and specification.

6. Package

  • 25 kg/drum

  • 27 drums/pallet

  • Custom packaging available for OEM/ODM projects.

7. Main Markets

We supply global buyers across:

  • Europe

  • North America

  • Asia-Pacific

  • Expanding partners in the Middle East and South America

8. Applications & Key Functions

Yohimbine Extract is used across several industries thanks to its well-studied physiological effects and fast formulation compatibility.

Main Functions:

  • Supports thermogenesis and fat mobilization

  • Enhances circulation and blood flow

  • Contributes to energy, alertness, and exercise performance

  • Traditional uses in male vitality and wellness formulations

  • Potential antioxidant support (anthocyanin-fortified versions)

Industry Applications:

  • Dietary Supplements: fat burners, pre-workout formulas, metabolism blends

  • Sports Nutrition: cutting-phase formulas, energy boosters

  • Herbal Health Products: vitality, circulation, performance

  • Functional Foods & Beverages: energy shots, performance drinks (water-soluble grade)

  • Pharmaceutical Preparations: circulation and wellness support (region-specific)

  • Cosmetic/Topical Formulas: microcirculation-focused serums or creams

Yohimbine Extract (98%) – High-Purity Botanical Active for Global Supplement Formulators

Manufactured by AIHerba® (Shaanxi Zhonghong Investment Technology Co., Ltd.)
GMP-certified botanical extract manufacturer | Plant extract factory China
📧 sales@aiherba.com | info@aiherba.com | liaodaohai@gmail.com
🌐 www.aiherba.com


1. Product Overview

Yohimbine is an alkaloid naturally derived from the bark of Pausinystalia yohimbe. Known for its effects on blood flow, metabolism, and energy balance, Yohimbine has become a widely used active in sports nutrition, weight management formulas, and male vitality supplements.

At AIHerba, we produce high-purity Yohimbine (typically 8%, 98%, or Yohimbine HCL) using modern extraction and purification technologies. Our 28+ years of factory experience, GMP production, and third-party testing ensure reliable, traceable quality for global B2B clients looking to buy Yohimbine in bulk.


2. Botanical Source & Production Origin

  • Botanical Name: Pausinystalia yohimbe

  • Plant Part Used: Bark

  • Extraction Technology: Water–ethanol extraction + column purification

  • Available Grades: Yohimbine 8%, Yohimbine 98%, Yohimbine HCL

  • Appearance: Fine white to brownish powder (depending on purity)

  • Standard Packaging: 1 kg aluminum foil bag; 25 kg drum


3. Key Benefits & Mechanisms

(1) Supports Circulation & Blood Flow

Yohimbine acts as an α2-adrenergic receptor antagonist, promoting vasodilation and improved peripheral blood flow.
Referenced in: NIH & PubMed studies.

(2) Promotes Fat Mobilization

Yohimbine enhances lipolysis, especially during fasted conditions—commonly used in weight management formulas and sports nutrition products.

(3) Energy, Alertness & Physical Performance

Its stimulating properties make Yohimbine a frequent inclusion in pre-workout blends.

(4) Traditional Use for Male Vitality

Historically used in West African herbal medicine to support sexual wellness and stamina.


4. Applications & Suitable Industries

This ingredient is widely used by:

  • Dietary supplement manufacturers

  • Sports nutrition brands

  • Functional food formulators

  • Botanical extract supplier networks

  • Pharmaceutical health product manufacturers

  • Cosmetic & topical formula developers (circulation-focused products)

Popular product formats:

  • Capsules

  • Tablets

  • Pre-workout powders

  • Slimming formulas

  • Liquid tinctures

  • Herbal blends


5. Recommended Dosage & Usage Guide

(Always follow local regulations.)

  • Yohimbine HCL 98%: typically 2–5 mg per serving, not exceeding 15–20 mg daily

  • Yohimbine 8% extract: typically 50–200 mg per day

  • Best taken on an empty stomach for fat-mobilization formulas.

  • Not recommended during late evening due to stimulatory effects.


6. Contraindications & Safety Notes

Do NOT use Yohimbine if:

  • Pregnant or breastfeeding

  • Diagnosed with cardiovascular disease

  • Taking antidepressants (MAOIs/SSRIs), stimulants, or hypertension medication

  • You have anxiety disorder, arrhythmia, high blood pressure, or kidney disease

Common side effects (dose-dependent):

  • Rapid heartbeat

  • Nervousness

  • Increased blood pressure

  • Gastrointestinal discomfort

Regulatory Note:

  • Yohimbine is regulated differently across markets.

  • Check FDA, EFSA, Health Canada, and regional guidelines before formulation.


7. Best Formulation Practices (B2B Formulator Guide)

  • Combine with caffeine, green tea extract, or synephrine for thermogenic blends.

  • Use controlled-release matrices for improved tolerability.

  • Pair with L-arginine or L-citrulline for circulation-focused formulas.

  • Stabilize with moisture-control agents due to alkaloid sensitivity.


8. COA-Style Specification Sheet (Example)

8.1 General Specifications

Item Specification Test Method
Appearance White to off-white powder Visual
Purity (Yohimbine) ≥ 98% HPLC
Loss on Drying ≤ 2.0% USP
Residue on Ignition ≤ 0.3% USP
Identification Positive HPLC/IR

8.2 Pesticide Residue Screening

Pesticide Limit Method
Organochlorines ≤ 0.1 mg/kg GC-MS
Organophosphates ≤ 0.1 mg/kg GC-MS
Pyrethroids ≤ 0.1 mg/kg GC-MS
Multi-residue panel (500+) Complies LC-MS/MS

8.3 Heavy Metals

Heavy Metal Limit Method
Lead (Pb) ≤ 2.0 ppm ICP-MS
Arsenic (As) ≤ 1.0 ppm ICP-MS
Cadmium (Cd) ≤ 1.0 ppm ICP-MS
Mercury (Hg) ≤ 0.1 ppm ICP-MS

8.4 Microbiology

Test Item Limit Method
Total Plate Count ≤ 10,000 cfu/g USP <2021>
Yeast & Mold ≤ 300 cfu/g USP <2021>
E. coli Negative USP <2022>
Salmonella Negative USP <2022>
Staphylococcus aureus Negative USP <2022>

9. Manufacturing Process & Workflow

(1) Raw Material Sourcing

Verified Pausinystalia yohimbe from audited plantations.

(2) Pre-Processing

Cleaning → Cutting → Drying → Milling

(3) Extraction

Water–ethanol extraction under controlled temperature.

(4) Purification

Column chromatography to isolate Yohimbine alkaloids.

(5) Concentration & Drying

Vacuum concentration + spray drying or crystallization.

(6) Milling & Sieving

Particle size homogenization (80–120 mesh).

(7) Quality Control

HPLC purity check
Microbial testing
Heavy metals testing
Stability evaluation

(8) Packaging

GMP clean-room environment.


10. Storage, Shelf Life & Packaging

  • Storage: Keep in a cool, dry, sealed container away from light and humidity.

  • Shelf Life: 24–36 months under recommended storage.

  • Packaging:

    • 1 kg aluminum foil bag

    • 25 kg fiber drum

    • Custom packaging available


11. Shipping, MOQ & Sample Policy

  • MOQ: 1 kg for standard orders

  • Samples: Free 10–20 g sample available (shipping cost negotiable)

  • Shipping: FedEx, DHL, UPS, air cargo, or sea freight

  • Lead Time: 3–7 days for bulk orders; custom specifications 10–15 days


12. Why Work With AIHerba®

Experience (28+ years)

We operate as a GMP-certified herbal extract supplier and botanical extract manufacturer with a strong track record across nutraceutical, cosmetic, and pharmaceutical sectors.

Authority

  • GMP, ISO9001, HACCP

  • Full COA, MSDS, TDS, and third-party test reports

  • Traceable raw material sourcing

Credibility

  • Factory production photos

  • Batch-to-batch consistency

  • Transparent testing standards

B2B Advantage

  • Competitive bulk pricing from a China plant extract factory

  • Stable inventory

  • OEM & ODM support for customized herbal extract formulations


13. Frequently Asked Questions (FAQ)

Q1: Can I buy Yohimbine in bulk directly from the manufacturer?
Yes—AIHerba is a GMP-certified factory offering Yohimbine wholesale, bulk supply, and customization.

Q2: Is Yohimbine legal in my country?
Regulations vary. Always check with your local authority (FDA, EFSA, TGA, etc.).

Q3: How do you ensure purity and safety?
We test every batch via HPLC, ICP-MS, GC-MS, and microbial assays.

Q4: Do you provide free samples before purchase?
Yes—free samples are available for qualified buyers.


14. Scientific References (PubMed / NIH / FDA)

  1. PubMed: Yohimbine and α2-adrenergic receptor function

  2. NIH Database: Yohimbine effects on lipolysis

  3. FDA: Regulatory classification for Yohimbine-containing supplements

  4. PubMed: Yohimbine pharmacokinetics and safety profile

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