Yohimbine Extract (98%) – High-Purity Botanical Active for Global Supplement Formulators
Manufactured by AIHerba® (Shaanxi Zhonghong Investment Technology Co., Ltd.)
GMP-certified botanical extract manufacturer | Plant extract factory China
📧 sales@aiherba.com | info@aiherba.com | liaodaohai@gmail.com
🌐 www.aiherba.com
1. Product Overview
Yohimbine is an alkaloid naturally derived from the bark of Pausinystalia yohimbe. Known for its effects on blood flow, metabolism, and energy balance, Yohimbine has become a widely used active in sports nutrition, weight management formulas, and male vitality supplements.
At AIHerba, we produce high-purity Yohimbine (typically 8%, 98%, or Yohimbine HCL) using modern extraction and purification technologies. Our 28+ years of factory experience, GMP production, and third-party testing ensure reliable, traceable quality for global B2B clients looking to buy Yohimbine in bulk.
2. Botanical Source & Production Origin
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Botanical Name: Pausinystalia yohimbe
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Plant Part Used: Bark
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Extraction Technology: Water–ethanol extraction + column purification
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Available Grades: Yohimbine 8%, Yohimbine 98%, Yohimbine HCL
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Appearance: Fine white to brownish powder (depending on purity)
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Standard Packaging: 1 kg aluminum foil bag; 25 kg drum
3. Key Benefits & Mechanisms
(1) Supports Circulation & Blood Flow
Yohimbine acts as an α2-adrenergic receptor antagonist, promoting vasodilation and improved peripheral blood flow.
Referenced in: NIH & PubMed studies.
(2) Promotes Fat Mobilization
Yohimbine enhances lipolysis, especially during fasted conditions—commonly used in weight management formulas and sports nutrition products.
(3) Energy, Alertness & Physical Performance
Its stimulating properties make Yohimbine a frequent inclusion in pre-workout blends.
(4) Traditional Use for Male Vitality
Historically used in West African herbal medicine to support sexual wellness and stamina.
4. Applications & Suitable Industries
This ingredient is widely used by:
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Dietary supplement manufacturers
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Sports nutrition brands
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Functional food formulators
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Botanical extract supplier networks
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Pharmaceutical health product manufacturers
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Cosmetic & topical formula developers (circulation-focused products)
Popular product formats:
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Capsules
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Tablets
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Pre-workout powders
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Slimming formulas
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Liquid tinctures
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Herbal blends
5. Recommended Dosage & Usage Guide
(Always follow local regulations.)
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Yohimbine HCL 98%: typically 2–5 mg per serving, not exceeding 15–20 mg daily
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Yohimbine 8% extract: typically 50–200 mg per day
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Best taken on an empty stomach for fat-mobilization formulas.
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Not recommended during late evening due to stimulatory effects.
6. Contraindications & Safety Notes
Do NOT use Yohimbine if:
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Pregnant or breastfeeding
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Diagnosed with cardiovascular disease
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Taking antidepressants (MAOIs/SSRIs), stimulants, or hypertension medication
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You have anxiety disorder, arrhythmia, high blood pressure, or kidney disease
Common side effects (dose-dependent):
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Rapid heartbeat
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Nervousness
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Increased blood pressure
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Gastrointestinal discomfort
Regulatory Note:
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Yohimbine is regulated differently across markets.
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Check FDA, EFSA, Health Canada, and regional guidelines before formulation.
7. Best Formulation Practices (B2B Formulator Guide)
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Combine with caffeine, green tea extract, or synephrine for thermogenic blends.
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Use controlled-release matrices for improved tolerability.
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Pair with L-arginine or L-citrulline for circulation-focused formulas.
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Stabilize with moisture-control agents due to alkaloid sensitivity.
8. COA-Style Specification Sheet (Example)
8.1 General Specifications
| Item | Specification | Test Method |
|---|---|---|
| Appearance | White to off-white powder | Visual |
| Purity (Yohimbine) | ≥ 98% | HPLC |
| Loss on Drying | ≤ 2.0% | USP |
| Residue on Ignition | ≤ 0.3% | USP |
| Identification | Positive | HPLC/IR |
8.2 Pesticide Residue Screening
| Pesticide | Limit | Method |
|---|---|---|
| Organochlorines | ≤ 0.1 mg/kg | GC-MS |
| Organophosphates | ≤ 0.1 mg/kg | GC-MS |
| Pyrethroids | ≤ 0.1 mg/kg | GC-MS |
| Multi-residue panel (500+) | Complies | LC-MS/MS |
8.3 Heavy Metals
| Heavy Metal | Limit | Method |
|---|---|---|
| Lead (Pb) | ≤ 2.0 ppm | ICP-MS |
| Arsenic (As) | ≤ 1.0 ppm | ICP-MS |
| Cadmium (Cd) | ≤ 1.0 ppm | ICP-MS |
| Mercury (Hg) | ≤ 0.1 ppm | ICP-MS |
8.4 Microbiology
| Test Item | Limit | Method |
|---|---|---|
| Total Plate Count | ≤ 10,000 cfu/g | USP <2021> |
| Yeast & Mold | ≤ 300 cfu/g | USP <2021> |
| E. coli | Negative | USP <2022> |
| Salmonella | Negative | USP <2022> |
| Staphylococcus aureus | Negative | USP <2022> |
9. Manufacturing Process & Workflow
(1) Raw Material Sourcing
Verified Pausinystalia yohimbe from audited plantations.
(2) Pre-Processing
Cleaning → Cutting → Drying → Milling
(3) Extraction
Water–ethanol extraction under controlled temperature.
(4) Purification
Column chromatography to isolate Yohimbine alkaloids.
(5) Concentration & Drying
Vacuum concentration + spray drying or crystallization.
(6) Milling & Sieving
Particle size homogenization (80–120 mesh).
(7) Quality Control
HPLC purity check
Microbial testing
Heavy metals testing
Stability evaluation
(8) Packaging
GMP clean-room environment.
10. Storage, Shelf Life & Packaging
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Storage: Keep in a cool, dry, sealed container away from light and humidity.
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Shelf Life: 24–36 months under recommended storage.
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Packaging:
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1 kg aluminum foil bag
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25 kg fiber drum
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Custom packaging available
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11. Shipping, MOQ & Sample Policy
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MOQ: 1 kg for standard orders
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Samples: Free 10–20 g sample available (shipping cost negotiable)
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Shipping: FedEx, DHL, UPS, air cargo, or sea freight
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Lead Time: 3–7 days for bulk orders; custom specifications 10–15 days
12. Why Work With AIHerba®
Experience (28+ years)
We operate as a GMP-certified herbal extract supplier and botanical extract manufacturer with a strong track record across nutraceutical, cosmetic, and pharmaceutical sectors.
Authority
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GMP, ISO9001, HACCP
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Full COA, MSDS, TDS, and third-party test reports
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Traceable raw material sourcing
Credibility
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Factory production photos
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Batch-to-batch consistency
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Transparent testing standards
B2B Advantage
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Competitive bulk pricing from a China plant extract factory
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Stable inventory
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OEM & ODM support for customized herbal extract formulations
13. Frequently Asked Questions (FAQ)
Q1: Can I buy Yohimbine in bulk directly from the manufacturer?
Yes—AIHerba is a GMP-certified factory offering Yohimbine wholesale, bulk supply, and customization.
Q2: Is Yohimbine legal in my country?
Regulations vary. Always check with your local authority (FDA, EFSA, TGA, etc.).
Q3: How do you ensure purity and safety?
We test every batch via HPLC, ICP-MS, GC-MS, and microbial assays.
Q4: Do you provide free samples before purchase?
Yes—free samples are available for qualified buyers.
14. Scientific References (PubMed / NIH / FDA)
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PubMed: Yohimbine and α2-adrenergic receptor function
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NIH Database: Yohimbine effects on lipolysis
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FDA: Regulatory classification for Yohimbine-containing supplements
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PubMed: Yohimbine pharmacokinetics and safety profile





