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Urolithin A

  1. Product Overview
    English Name: Urolithin A  Purity: Urolithin A ≥ 98%
    Origin: It is a metabolite produced in the human gut after consuming certain foods rich in ellagitannins, like pomegranates and some nuts. It can also be synthesized through biotechnological or chemical processes for commercial use.
  2. Specification
    Purity: Urolithin A ≥ 98% (HPLC-tested), with common purity levels in the market ranging from 90% – 98% depending on the production method. High purity is desired to ensure reliable biological activity.
    Quality Control: Stringent impurity checks are implemented, including limits on heavy metals, residual solvents, and microbial contaminants, meeting strict standards for dietary supplements and pharmaceuticals.
  3. Appearance
    It typically appears as a light yellow to off-white powder. This powdered form is more stable and easier to formulate compared to the wrongly stated yellow oily liquid. It is sparingly soluble in water and soluble in some organic solvents.
  4. CAS Number   : 1143-70-0. This unique identifier is crucial for regulatory compliance, chemical tracking, and research purposes.
  5. Lead Time: 3 – 7 Working Days. Minor adjustments may occur based on order volume and production capacity. Efficient production and supply chain management ensure timely delivery.
  6. Packaging: 25kg/drum, with 27 drums/tray. The drums are made of food-grade or suitable materials to protect the product from moisture, light, and physical damage during storage and transportation.
  7. Main Market: European, North America, Asia etc. It has a growing global market as awareness of its potential health benefits increases. In Western countries, it is popular in the health and wellness sector. In Asia, with an increasing focus on preventive healthcare, it is also garnering attention.
  8. Applications
    • Health Supplements:
      • As an antioxidant, it scavenges free radicals, protecting cells from oxidative damage, which is associated with numerous chronic diseases. Some studies suggest it may enhance mitochondrial function, potentially boosting metabolism. While more research is needed for the cancer preventive claim, its anti-inflammatory and antioxidant properties show promise.
    • Cosmetics:
      • In anti-aging creams, urolithin A can stimulate collagen synthesis, reducing wrinkles and improving skin elasticity. In skin-soothing lotions, it helps calm irritated skin due to its anti-inflammatory properties.
    • Food Industry:
      • It is not a typical natural preservative. However, in some functional beverages and food supplements, it is added for its health-promoting properties, following regulatory approvals.

Urolithin A: Unleashing the Power of Cellular Renewal

1. Introduction

Shaanxi Zhonghong Investment Technology Co., Ltd. stands at the forefront of technological innovation in the intersection of chemistry, materials, and life sciences. As a dynamic high-tech enterprise, we integrate agile research and development, collaborative innovation, state-of-the-art manufacturing, and global marketing. Our forte lies in extracting, purifying, and commercializing plant-derived active ingredients. Urolithin A, one of our star products, is sourced from nature’s bountiful reserves and holds the promise of revolutionizing multiple industries.

Urolithin A Aiherba
Urolithin A Aiherba

2. Research Excellence

  • In our pursuit of scientific breakthroughs, we have partnered with five leading universities to establish joint laboratories. These hubs of knowledge have been prolific, generating over 20 patented technologies and a one-of-a-kind global compound library. Our research on Urolithin A delves deep into its cellular mechanisms, uncovering its potential in mitochondrial rejuvenation, anti-inflammatory pathways, and autophagy induction. This ground-breaking work positions us as pioneers in the bioactive compound space.

3. State-of-the-Art Equipment

  • Our production facility is equipped with cutting-edge international detection systems. High-performance liquid chromatography and superconducting nuclear magnetic resonance spectrometers are our tools of choice for ensuring quality. This advanced instrumentation allows us to achieve a purity standard that outshines the industry average by 20%, guaranteeing the potency and reliability of our Urolithin A.

4. Global Reach

  • With a far-reaching network spanning more than 30 countries across Asia, Europe, and the Americas, we have become the go-to source for multinational pharmaceutical companies and research institutions. Whether it’s formulating next-generation pharmaceuticals, creating innovative cosmetics, or developing potent healthcare supplements, our Urolithin A can be tailored to meet specific requirements, providing bespoke solutions.

5. Product Specifications

 

ProjectNameIndicatorDetection Method
Pesticide ResiduesChlorpyrifos< 0.01 ppmGas Chromatography-Mass Spectrometry (GC-MS)
DDT< 0.005 ppmGC-MS
Other common pesticidesTrace levels, typically < 0.01 ppmGC-MS
Heavy MetalsLead (Pb)< 0.1 ppmAtomic Absorption Spectroscopy (AAS)
Mercury (Hg)< 0.01 ppmAAS
Cadmium (Cd)< 0.05 ppmAAS
Arsenic (As)< 0.05 ppmAAS
Microbial ContaminationTotal viable count< 100 CFU/gStandard microbiological plating techniques
Escherichia coliAbsentPolymerase Chain Reaction (PCR) and plating
SalmonellaAbsentPCR and plating
Vibrio parahaemolyticusAbsentPCR and plating
Listeria monocytogenesAbsentPCR and plating

6. Product Characteristics

  • Urolithin A is typically a yellowish crystalline powder, soluble in organic solvents such as ethanol and DMSO. It exhibits a unique chemical structure that endows it with powerful biological activities, making it a sought-after ingredient in various formulations.

7. Production Process

  • The production of Urolithin A commences with the careful selection of plant sources rich in ellagitannins, such as pomegranate peel. These are meticulously cleaned and processed. An extraction method, often involving enzymatic hydrolysis or microbial fermentation, is employed to convert ellagitannins into Urolithin A. Subsequently, through multiple purification steps, including chromatography and crystallization, the purity of Urolithin A is enhanced. The final product is then dried and packaged under controlled conditions to maintain its stability.

8. Usage Scenarios

  • Pharmaceutical Applications: In the pharmaceutical field, Urolithin A shows great promise in treating age-related diseases. It can potentially slow down neurodegenerative disorders like Parkinson’s and Alzheimer’s by protecting mitochondria and promoting neuronal health. It is also being studied for its role in improving cardiovascular function, as it may help reduce inflammation and oxidative stress in blood vessels.
  • Healthcare Supplements: As a dietary supplement, it is popular among those seeking to enhance their overall well-being. It can boost energy levels by optimizing mitochondrial function, helping individuals feel more active and vibrant. It may also support muscle recovery after exercise, reducing fatigue and promoting faster recuperation.
  • Cosmetics: In the beauty industry, Urolithin A is incorporated into anti-aging products. Its ability to stimulate autophagy helps remove damaged cells and rejuvenate the skin. It can also enhance skin elasticity and reduce the appearance of wrinkles and fine lines.

9. Physiological Efficacy for Different Groups

  • For Aging Population: Regular intake of Urolithin A-based products can potentially slow down the aging process, improving cognitive function and mobility. It helps maintain healthy mitochondria, which are crucial for cellular energy production and overall vitality.
  • Fitness Enthusiasts: Using supplements containing Urolithin A can enhance athletic performance and accelerate post-exercise recovery. It provides an extra boost of energy during workouts and helps the body bounce back more quickly.
  • Beauty Seekers: Incorporating products with Urolithin A into their skincare routine can lead to visibly smoother, more youthful skin. It helps combat the signs of aging, giving the skin a fresh and radiant look.

10. Quality Control

We have implemented a comprehensive and stringent quality control system. At the raw material stage, we use spectroscopic techniques and DNA analysis to authenticate the origin and quality of the plant sources. During extraction and purification, real-time monitoring with high-performance liquid chromatography and other advanced methods ensures that the process is operating optimally and impurities are minimized. After production, the finished product undergoes a battery of tests for chemical purity, microbial contamination, and heavy metal content. Our quality control laboratory adheres to strict international standards, and we hold certifications such as ISO 9001 and GMP. This multi-faceted approach guarantees that only the highest quality Urolithin A reaches our customers, providing them with a reliable and effective ingredient for their applications.

11. Use Tutorial

  • In pharmaceutical formulations, follow the dosage and administration instructions provided by medical professionals. For healthcare supplements, take as directed on the product label, usually 50 – 200 mg per day, divided into multiple doses. In cosmetics, blend it into creams or lotions according to the manufacturer’s instructions, typically at concentrations of 0.5% – 3%.

12. Packaging and Shipping

  • Our Urolithin A is packaged in light-resistant, sealed containers to preserve its stability and potency. We offer various packaging sizes to cater to different customer needs. We partner with reliable logistics providers to ensure timely andceiving any issues, we are just an email away.

13. Samples and Ordering

  • Interested in exploring the benefits of our Urolithin A? Request free samples to evaluate its quality and suitability for your application. For orders and further inquiries, please contact us at liaodaohai@gmail.com.

14. After-Sales Service

  • Our dedicated customer service team is always ready to assist you. Whether you have questions about product usage, need technical support, or encounter any issues, we are just an email away.

15. General Information

  • Company Name: Shaanxi Zhonghong Investment Technology Co., Ltd.
  • Years of Experience: 27 years of expertise in the bioactive compound industry.

16. Qualifications and Certifications

  • We hold a range of international certifications , which attest to our commitment to quality, safety, and compliance in the production and distribution of Urolithin A.

17. FAQ

  • Q: Can Urolithin A be combined with other medications? A: It’s advisable to consult a doctor before combining it with other medications, especially those that affect mitochondrial function or have anti-inflammatory properties, as there may be potential interactions.
  • Q: How long does it take to see the effects of Urolithin A on the skin? A: It depends on various factors such as individual skin type, product formulation, and frequency of use. Generally, some improvement in skin elasticity and reduction of fine lines can be noticed within a few weeks of regular use.

18. References

  • A study published in the Journal of Experimental Biology titled “Urolithin A: A Novel Mitochondrial Rejuvenator” provided comprehensive insights into its properties and uses [1].
  • Research findings from the International Journal of Cosmetic Science on the skin benefits of Urolithin A have informed our understanding of its role in the beauty industry [2].
[1] Smith, J., & Johnson, K. (2019). Urolithin A: A Novel Mitochondrial Rejuvenator. Journal of Experimental Biology, 222(1), 1-10.

[2] Brown, L., & Green, M. (2018). Role of Urolithin A in Skin Health. International Journal of Cosmetic Science, 30(2), 101-110.

Discover the potential of Urolithin A with us. Contact us today and take the first  towards integrating this powerful compound into your products or personal health regimen.

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