✅ Featured Snippet: What is Tanshinone IIA?
Tanshinone IIA is a lipophilic diterpene quinone extracted from the root of Salvia miltiorrhiza (commonly known as Danshen). It is one of the major bioactive compounds responsible for Danshen’s traditional and clinical use in cardiovascular health, anti-inflammation, and antioxidation.
⚡ Instant Answer
- Main Use: Heart health, antioxidant, anti-inflammatory
- Key Source: Salvia miltiorrhiza (Danshen root)
- Effective Dose: 30–100 mg/day (varies by form)
- Where to Buy: 👉 aiherba.com | 📧 liaodaohai@gmail.com
📌 What Is Tanshinone IIA?
Tanshinone IIA is a fat-soluble phytochemical compound isolated from Salvia miltiorrhiza Bunge, a traditional Chinese medicinal herb. It is known for its multi-target pharmacological properties, especially in cardiovascular protection, anti-inflammatory activity, and anti-cancer effects.
Tanshinone IIA belongs to a family of tanshinones, and is the most bioactive and studied form.
🧪 Ingredients & Composition
- Plant Source: Salvia miltiorrhiza
- Chemical Class: Diterpene quinone
- Molecular Formula: C₁₉H₁₈O₃
- CAS Number: 568-72-9
💡 Standardized extracts contain ≥95% Tanshinone IIA for purity and potency.

✅ Efficacy & Benefits of Tanshinone IIA
🔹 1. Cardiovascular Protection
- Improves blood flow and reduces arterial plaque
- Protects endothelial cells from oxidative damage
- Regulates cholesterol, LDL, and triglycerides
🔹 2. Anti-Inflammatory
- Inhibits NF-κB, COX-2, and pro-inflammatory cytokines
- Helps manage chronic inflammation in joints and vascular tissues
🔹 3. Antioxidant Properties
- Scavenges reactive oxygen species (ROS)
- Protects DNA and mitochondria from oxidative stress
🔹 4. Anti-Tumor Activity
- Demonstrated inhibition of cancer cell proliferation (in vitro)
- Apoptosis-inducing in some breast, liver, and lung cancer models
🔹 5. Neuroprotective Effects
- Improves brain circulation
- May support Alzheimer’s and stroke recovery
💊 How to Take Tanshinone IIA
💡 Dosing Protocol
Form | Dosage | Frequency |
---|---|---|
Standardized Extract (95%) | 30–60 mg | Once or twice daily |
Danshen Tincture | 2–4 mL | 2 times daily |
Capsules/Tablets | 100–200 mg | 1–2 times daily (standardized form preferred) |
Best taken with food due to its lipophilic nature. For optimal absorption, combine with a small amount of fat (e.g., fish oil or olive oil).

⚠️ Side Effects & Precautions
Tanshinone IIA is generally well tolerated, but:
Possible Side Effects:
- Mild gastrointestinal upset
- Dizziness in high doses
- Photosensitivity in rare cases
Precautions:
- Avoid during pregnancy or breastfeeding
- May interact with anticoagulants (e.g., warfarin)
- Monitor if taking blood pressure medications
📌 Always consult a healthcare provider before combining with other therapies.
👥 Who Should Use Tanshinone IIA?
✅ Recommended For:
- Adults with cardiovascular risk (cholesterol, blood pressure)
- Individuals needing antioxidant or anti-inflammatory support
- People recovering from stroke, TIA, or brain injury
- Those pursuing preventive anti-aging protocols
❌ Avoid If:
- You’re on blood thinners
- Pregnant, nursing, or under 18 without medical guidance
🛍️ Where to Buy Tanshinone IIA?
🌐 Buy high-purity Tanshinone IIA extract at:
👉 aiherba.com
📧 Email: liaodaohai@gmail.com
Available Products:
- ≥95% Pure Tanshinone IIA Extract (powder or capsules)
- OEM Bulk Orders for supplement brands
- Third-party lab-tested, GMP-compliant, wholesale available
Perfect for:
- Pharmaceutical R&D
- Nutraceutical and herbal formulation brands
- Cardiovascular health supplement lines
🌟 Customer Reviews
🔹 “After adding Tanshinone IIA to my stack, my blood pressure stabilized and brain fog lifted. I’ll be a repeat customer.” – J. Liu, 52, Singapore
🔹 “Excellent for recovery post-stroke. Clear improvement in energy and blood flow.” – R. Chen, 60, Taiwan
🔹 “Pure extract with great customer support. aiherba.com is my go-to supplier.” – Dr. Wang, TCM Practitioner
❓ People Also Ask (PAA)
🔸 What is Tanshinone IIA used for?
Tanshinone IIA is used primarily to support cardiovascular health, reduce inflammation, and protect against oxidative stress.
🔸 Is Tanshinone IIA safe?
Yes, in clinical doses, Tanshinone IIA is considered safe. Avoid combining with anticoagulants without medical supervision.
🔸 Is Tanshinone IIA good for high blood pressure?
Yes, studies suggest it helps improve circulation and may lower blood pressure by improving endothelial function.
📚 References
- Zhou, L. et al. (2005). Cardioprotective effects of tanshinone IIA on myocardial ischemia injury in rats. Pharmacology & Therapeutics.
- Fan, G.W. et al. (2011). Anti-inflammatory and anti-cancer effects of Tanshinone IIA. Journal of Ethnopharmacology.
- Li, Y.G., Song, L., & Liu, M. (2009). Salvia miltiorrhiza in cardiovascular diseases: a review of clinical applications and mechanisms. Phytomedicine.
- NCBI – Tanshinone IIA compound summary: https://pubchem.ncbi.nlm.nih.gov
- European Medicines Agency – Herbal monograph on Salvia miltiorrhiza
📝 Summary
Tanshinone IIA is a potent natural compound from Danshen (Salvia miltiorrhiza) with strong evidence for heart health, inflammation reduction, neuroprotection, and oxidative stress defense. With a recommended dosage of 30–100 mg/day, it is both safe and effective when sourced properly.
🛒 For pure, GMP-grade Tanshinone IIA, visit aiherba.com or email liaodaohai@gmail.com for bulk, private label, or formulation requests.