Explore Tanshinone IIA properties, benefits, and applications in cosmetics, supplements, and functional foods. Expert sourcing from a trusted factory.
Tanshinone IIA extract, sourced from premium Salvia miltiorrhiza (Danshen) roots, is offered in high-purity grades (≥95%, 98%) for research, pharmaceutical, nutraceutical, and cosmetic applications. AIHerba®, a GMP-certified manufacturer and OEM factory, provides bulk and wholesale solutions with full COA, traceable supply chains, and global export capability. Our 28+ years of experience in plant extraction—including supercritical CO₂ and water-ethanol extraction—ensures high stability, reproducibility, and potency for your formulations. Whether you require Tanshinone IIA for functional foods, dietary supplements, or high-quality raw material sourcing, AIHerba delivers consistent quality, flexible MOQ, and OEM/ODM customization services to accelerate product development and market entry. Contact us for quotes, sample requests, or technical guidance.
1. What is Tanshinone IIA?
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Tanshinone IIA is a diterpenoid quinone derived from Salvia miltiorrhiza (Danshen) roots, a traditional Chinese medicinal plant. It is a lipophilic compound with documented chemical purity (CAS 568-72-9) and molecular formula C₁₉H₁₈O₃. AIHerba supplies Tanshinone IIA extract in standardized concentrations suitable for industrial applications, research studies, and product development in nutraceuticals and cosmetics.
2. Product Source & Extraction
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Raw Material: Premium Danshen roots sourced from certified farms in Shaanxi, China.
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Extraction Methods: Supercritical CO₂ extraction, water-ethanol extraction, and microbial fermentation.
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Purity Grades Available: ≥95%, ≥98%, ≥99% HPLC verified.
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Certifications: GMP, ISO, HACCP, Kosher, Halal (optional).
3. Mechanism of Action & Functional Benefits
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Tanshinone IIA primarily acts as a bioactive phytochemical with antioxidant and cellular signaling regulatory potential. Mechanisms include:
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Supporting mitochondrial function and oxidative balance
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Modulating inflammatory pathways (e.g., NF-κB signaling)
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Influencing apoptosis and cell cycle regulation in research contexts
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Note: Benefits described are for research and formulation purposes; no medical claims are made.
4. Traditional Applications & Research Uses
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Historically used in traditional Chinese medicine formulations. Modern applications include:
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Nutraceuticals and dietary supplements
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Cosmetic active ingredients for skin formulation studies
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Pharmaceutical and functional food research
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Recommended Use in Formulations: Concentration depends on final product type, purity, and stability requirements. Our technical team can provide guidance on optimal inclusion rates.
5. Product Specifications & COA
| Category | Parameter | Specification | Test Method |
|---|---|---|---|
| Purity | HPLC | ≥98% | HPLC |
| Appearance | Solid | Yellow-red powder | Visual |
| Loss on Drying | – | ≤2% | Gravimetric |
| Ash | – | ≤1% | Gravimetric |
| Residual Solvents | – | Compliant with USP | GC |
| Heavy Metals | Lead (Pb) | ≤10 ppm | ICP-MS |
| Arsenic (As) | ≤2 ppm | ICP-MS | |
| Cadmium (Cd) | ≤1 ppm | ICP-MS | |
| Mercury (Hg) | ≤0.1 ppm | ICP-MS | |
| Microbial | Total Plate Count | ≤1000 CFU/g | AOAC 990.12 |
| Yeast & Mold | ≤100 CFU/g | AOAC 997.02 | |
| E. coli | Not detected | AOAC 991.14 | |
| Salmonella | Not detected | AOAC 2004.03 |
6. Production Process
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Raw material inspection → 2) Cleaning & drying → 3) Extraction (CO₂ / ethanol) → 4) Filtration → 5) Concentration → 6) Spray drying → 7) Quality testing & COA → 8) Packaging
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7. Storage, Shelf Life & Packaging
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Storage: Store in a cool, dry, dark place, away from direct sunlight.
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Shelf Life: 24 months under recommended storage.
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Packaging: 25 kg/drum, customizable.
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Sample Policy: Available for qualified B2B partners.
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Transportation & MOQ: Worldwide export; minimum order quantity 1 kg.
8. Clinical Data & Latest Research
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Tanshinone IIA research includes studies on cellular signaling, oxidative stress, and bioactive formulation development. Key references:
9. Industry Applications & Use Cases
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Cosmetics: Anti-aging & skin protective formulations
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Dietary Supplements: Research ingredient for formulation studies
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Functional Foods: Phytochemical additive in health-promoting foods
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Pharmaceutical Research: Preclinical studies, lab-scale applications
10. Usage Guidelines & Best Formulation Practices
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Concentration and formulation depend on product type. Our technical service team provides guidance for:
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Solubility optimization
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Stability in emulsions or dry blends
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Combination with synergistic plant extracts
11. FAQ
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Q: What purity levels are available?
A: ≥95%, ≥98%, and ≥99% HPLC verified. -
Q: Can AIHerba provide COA and GMP documentation?
A: Yes, full COA and certificates are available. -
Q: What industries can use Tanshinone IIA?
A: Cosmetics, dietary supplements, functional foods, and research labs. -
Q: What is the recommended MOQ?
A: Minimum order quantity is 1 kg; samples available on request. -
Q: How should it be stored?
A: Store in a cool, dry, dark place; shelf life 24 months. -
Q: Can it be customized for OEM/ODM formulations?
A: Yes, AIHerba provides full OEM/ODM support for global partners.
12. References & Regulatory Links
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PubMed: Tanshinone IIA Studies
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NIH Research: Danshen Bioactives
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AOAC Testing Methods: AOAC Official Methods
Contact AIHerba® for Bulk Quotes, Samples, and OEM Formulation Support
📧 sales@aiherba.com | info@aiherba.com | liaodaohai@gmail.com
🌐 www.aiherba.com
AIHerba® | Trusted GMP Manufacturer & Supplier of High-Purity Natural Plant Extracts – 28+ Years of Expertise, Verified COA, Global Export Ready.





