Spermidine Trihydrochloride Manufacturer: Wholesale Powder Price
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Spermidine 3HCl Bulk Supplier | 98% Purity | AIHerba® Factory

Spermidine – Natural Longevity & Cellular Renewal Extract 

  1. Product Name: Spermidine

  2. Specification: ≥98% (HPLC); water-soluble and oil-soluble forms available

  3. Appearance: Yellowish-white crystalline powder with a mild characteristic odor

  4. CAS Number: 124-20-9

  5. Lead Time: 3–7 working days

  6. Packaging: 25 kg/drum, 27 drums per tray

  7. Main Markets: Europe, North America, Asia

  8. Key Benefits: Natural polyamine, supports cellular health, longevity research, and formulation stability

  9. Industry Applications:
    Dietary Supplements: Longevity, cellular health, and wellness formulations
    Functional Foods & Beverages: Anti-aging drinks, nutrition powders, gummies
    Pharmaceutical Raw Materials: Research and specialty health products
    Contract Manufacturing / Private Label: Capsules, tablets, powders, and softgels

Bulk Supply & Technical Advisory
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GMP Certified
🔬
HPLC Lab Tested
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Global Logistics
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01. Spermidine 3HCl Bulk Supplier — Procurement Summary

Manufacturer: AIHerba® (Direct Factory)
Grade: Pharma / Nutraceutical / Cosmetic
Assay: ≥ 98.0% (HPLC Verified)
Form: Crystalline Isolate (3HCl Salt)
MOQ: 1kg (R&D) / 25kg (Production)
Lead Time: 3–7 Working Days
Inventory: 1,500kg Stock in Hubs
Logistics: Global DDP/CIF (Customs Pre-cleared)

02. Manufacturer & Quality Assurance Platform

AIHerba® Industrial Infrastructure

Operated by Shaanxi Zhonghong Investment Technology Co., Ltd., we utilize a specialized bio-synthesis platform for Spermidine 3HCl. We resolve the common industrial challenge of hygroscopic instability by utilizing high-vacuum crystallization. Our system ensures 100% batch-to-batch consistency and full regulatory documentation for US and EU markets.

GMP Certified
NMR Identity Verified
Heavy Metal Trace
DDP Logistics

03. Spermidine 3HCl Identity Profile

Chemical Name Spermidine Trihydrochloride
CAS Number 334-50-9
Molecular Weight 254.58 g/mol
Molecular Formula C7H22Cl3N3
Source Biomimetic Synthesis (Non-GMO Fermentation derived)

04. Technical Specification & Release Standard

ASSAY (HPLC)

≥ 98.0%

SPECIFIC IMPURITIES

≤ 1.0%

LOSS ON DRYING

≤ 1.0%

PH (5% WATER SOL.)

3.0 – 6.0

05. Analytical Verification & Scientific Fingerprint

Spermidine 3HCl identity verification is critical to prevent isomer confusion. AIHerba release includes full spectral proof.

HPLC-ELSD
Purity & Assay
1H-NMR
Structural ID
LC-MS
Mass Confirmation

* Illustrative Technical Simulation: Every industrial lot is released with raw spectral evidence.

06. Batch Release & Quality Control System

01 Precursor Inspection
02 Controlled Synthesis
03 Multi-stage Crystallization
04 Quality Release (QA)

07. Manufacturing Process & Engineering Control

The AIHerba industrial production of Spermidine 3HCl utilizes High-Pressure Bio-Synthesis. By converting specific precursors via microbial catalysis, we achieve a crystalline isolate free from wheat-derived gluten or allergens. Our Nitrogen-Protected Drying stage prevents the amine oxidation commonly found in inferior commodity grades.

08. Molecular Structure & Functional Characteristics

Spermidine 3HCl is a stable trihydrochloride salt of the polyamine spermidine. Its industrial value lies in its high water solubility and molecular integrity. Functionally, it mimics the autophagy-inducing effects of the free base but with significantly improved stability for dry-blend formulations and liquid shot delivery systems.

09. Industrial Application Compatibility

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Pharma R&D

API-grade intermediate for senolytic research and cellular longevity clinical studies.

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Cosmetics

Functional property in autophagy-themed skincare and hair follicle rejuvenation serums.

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Nutraceuticals

Stable active for longevity capsules, powder mixes, and clear functional beverages.

10. Formulation Development Guide

Solubility & Mixing

Freely soluble in water. In formulation, add to the aqueous phase at room temperature. It produces a clear, colorless solution with zero turbidity.

pH Compatibility

Spermidine 3HCl is acidic in solution. For topical use, buffering to pH 5.0 – 6.0 is required to ensure skin barrier compatibility.

11. Stability & Transport Engineering

Risk: Extreme Hygroscopicity
Spermidine salts absorb atmospheric moisture rapidly, leading to deliquescence and assay loss.
Solution: Shipped in Argon-purged induction-sealed PE bags inside moisture-barrier fiber drums.

12. Regulatory & Compliance Documentation

BATCH COA
GLOBAL MSDS
TECHNICAL TDS
NON-GMO STAT.

 Product Specifications & COA

Spermidine Extract – Technical Table

Test Category Parameter Specification Method
Active Compound Spermidine Content ≥ 98% (HPLC) HPLC
Appearance Solid / Powder Yellowish-white Visual
Odor Characteristic Mild plant aroma Sensory

Pesticide Residue

Name Limit Method
Total Pesticides ≤ 10 ppm GC-MS
Organochlorine Pesticides ND GC-MS

Heavy Metals

Name Limit Method
Lead (Pb) ≤ 1.0 mg/kg ICP-MS
Arsenic (As) ≤ 1.0 mg/kg ICP-MS
Cadmium (Cd) ≤ 0.5 mg/kg ICP-MS
Mercury (Hg) ≤ 0.1 mg/kg ICP-MS

Microbiological Testing

Name Limit Method
Total Plate Count ≤ 1000 CFU/g AOAC 990.12
Yeast & Mold ≤ 100 CFU/g AOAC 997.02
E. coli Negative ISO 7251
Salmonella Negative ISO 6579

13. Packaging Storage & Global Shipping

Standard Packaging: 25kg net weight fiber drums. Logistics: Validated DDP (Duty Paid) shipping available for USA and Europe, ensuring door-to-door delivery with zero customs administrative friction.

14. Custom Specification & OEM Support

AIHerba offers Custom Particle Sifting (80-200 mesh) and Pre-mixed Solutions. We can adjust molecular concentrations for specialized liquid formulations used in anti-aging cosmetic lines.

15. Spermidine Market & Industry Insights

The global Spermidine market is shifting from “Wheat-Germ Crude Extracts” to Synthetic/Fermented Isolates (≥98%). Sourcing managers are increasingly prioritizing high-purity isolates to eliminate allergen risks (Gluten) while achieving the high doses required for modern autophagy protocols.

16. Market Benchmark: Isolate vs. Crude Extract

Metric Wheat Germ Extract (Crude) AIHerba® Spermidine Isolate
Active Concentration 0.1% – 1.0% ≥ 98.0% (HPLC)
Allergen Risk High (Gluten/Wheat) Allergen-Free
Solubility Partial / Cloudy 100% Water Soluble

17. Technical Procurement FAQ

Q1: Why is Spermidine 3HCl used instead of the free base form?
The free base is an oily liquid at room temperature and highly unstable. The trihydrochloride (3HCl) salt form is a stable crystalline powder, allowing for accurate industrial weighing, mixing, and a 3-year shelf life.
Q2: Does your Spermidine isolate contain any gluten?
No. AIHerba’s high-purity Spermidine 3HCl is produced via bio-synthesis/fermentation, not wheat extraction. It is 100% gluten-free and non-allergenic.
Q3: What analytical method is used to verify the assay?
We utilize HPLC with ELSD or CAD detection (since the molecule lacks strong UV chromophores). Every batch is released against a validated reference isolate.
Q4: What is the lead time for a 100kg DDP order to the USA?
Dispatch occurs within 3 days from inventory. Total transit door-to-door to a US warehouse typically takes 10-14 days via air-DDP.

18. AIHerba Industrial Quality Commitment

✓ GMP Manufacturing
✓ Batch NMR Release
✓ Toluene-Free Certified
✓ Global DDP Export

Contact our engineering department for bulk quotes or technical dossiers.



Bulk Supply & Technical Advisory
🛡️
GMP Certified
🔬
HPLC Lab Tested
🌍
Global Logistics
📦
Free Samples
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