Spermidine – Natural Longevity & Cellular Renewal Extract | Bulk Supply & OEM Factory
High-Purity Spermidine Extract Supplier in China
AIHerba® (Shaanxi Zhonghong Investment Technology Co., Ltd.) is a GMP-certified manufacturer and exporter of natural Spermidine Extract, providing bulk raw materials for cosmetics, pharmaceuticals, dietary supplements, and functional food industries.
With over 28 years of R&D and production experience, our factory applies advanced microbial fermentation and purification technologies to produce high-purity spermidine with stable quality and traceable origin.
📧 Contact: sales@aiherba.com | info@aiherba.com | liaodaohai@gmail.com
🌐 Website: www.aiherba.com
1. Product Overview
| Product Name | Spermidine |
|---|---|
| Botanical Source | Derived from wheat germ or soybeans via microbial fermentation |
| Active Ingredient | Spermidine (C7H19N3) |
| Purity | ≥99% (HPLC) |
| Appearance | White to light yellow powder |
| Odor & Taste | Characteristic, slightly amine-like |
| CAS No. | 124-20-9 |
| Molecular Weight | 145.25 |
| Solubility | Soluble in water and ethanol |
| Shelf Life | 24 months under recommended storage conditions |
| Storage | Store in a cool, dry place away from direct sunlight and moisture |
2. Production Process & Technology
AIHerba employs bio-fermentation and multi-stage purification to ensure maximum purity and stability:
Production Flow:
- Raw material selection (non-GMO soybeans/wheat germ)
- Controlled microbial fermentation
- Extraction & concentration
- Ion-exchange purification
- Crystallization and drying
- Milling, sieving, and packaging under GMP standards
Each batch is fully traceable and tested according to USP, EP, and GB standards.
3. Key Benefits & Mechanisms
Cellular Longevity Support
Spermidine promotes autophagy, a cellular renewal process that removes damaged components, contributing to anti-aging and longevity effects.
Cognitive Health
Studies suggest spermidine supports neuronal function and may protect against age-related cognitive decline.
Cardiometabolic Balance
It helps maintain heart health by improving mitochondrial function and vascular elasticity.
Skin & Beauty Benefits
Spermidine is increasingly used in anti-aging skincare formulations for improving cell turnover and skin vitality.
Immune Support & Vitality
Supports DNA stability and enhances immune resilience through improved cellular metabolism.
4. Health Applications
| Industry | Application Examples |
|---|---|
| Dietary Supplements | Longevity capsules, cellular renewal formulas |
| Functional Foods | Anti-aging beverages, nutritional powders |
| Cosmetics | Anti-aging serums, rejuvenation creams |
| Pharmaceuticals | Cognitive and cardiovascular support formulas |
| Research Use | Cellular aging and autophagy studies |
5. Recommended Dosage & Usage Guide
- Dietary Supplement Use: 0.8–1.5 mg/day (based on human clinical data)
- Cosmetic Formulations: 0.1–1% in emulsions or serums
- Form Compatibility: Stable with Vitamin C, Resveratrol, and Coenzyme Q10
- Formulation Tips: Avoid high heat during mixing; ideal for encapsulation or aqueous formulations.
6. Product Specification & Quality Standards (COA)
A. Basic Parameters
| Item | Specification | Test Method |
|---|---|---|
| Appearance | White powder | Visual |
| Identification | Positive | HPLC / MS |
| Assay (Spermidine) | ≥99.0% | HPLC |
| Loss on Drying | ≤2.0% | GB 5009.3 |
| Residue on Ignition | ≤0.5% | GB 5009.4 |
B. Pesticide Residue Analysis
| Item | Limit (mg/kg) | Method |
|---|---|---|
| Organochlorine Pesticides | ≤0.1 | GC-MS |
| Organophosphorus Pesticides | ≤0.1 | GC-MS |
| Pyrethroids | ≤0.1 | GC-MS |
| Carbamates | ≤0.1 | LC-MS/MS |
C. Heavy Metal Testing
| Item | Limit | Method |
|---|---|---|
| Lead (Pb) | ≤1.0 ppm | ICP-MS |
| Arsenic (As) | ≤1.0 ppm | ICP-MS |
| Cadmium (Cd) | ≤0.5 ppm | ICP-MS |
| Mercury (Hg) | ≤0.1 ppm | ICP-MS |
D. Microbiological Tests
| Item | Limit | Method |
|---|---|---|
| Total Plate Count | ≤1000 CFU/g | GB 4789.2 |
| Yeast & Mold | ≤100 CFU/g | GB 4789.15 |
| E. coli | Negative | GB 4789.3 |
| Salmonella | Negative | GB 4789.4 |
| Staphylococcus aureus | Negative | GB 4789.10 |
7. Packaging, Storage & Logistics
| Packaging | 1kg aluminum foil bag; 25kg fiber drum |
|---|---|
| MOQ | 1kg (sample available) |
| Sample Policy | Free sample (≤50g); freight collect |
| Shelf Life | 24 months |
| Storage Conditions | Keep sealed, in a cool and dry environment (<25°C, RH <60%) |
| Transport | Shipped as non-hazardous cargo; worldwide air & sea logistics support |
8. Certifications & Quality Assurance
- GMP, ISO9001, HACCP certified production
- COA, MSDS, and third-party test reports available
- Complies with USP, EP, and GB standards
- Traceable supply chain with QR-coded batch records
- Third-party tested by Eurofins / SGS
9. Recommended Formulation Synergy
| Ingredient | Function |
|---|---|
| Resveratrol | Enhances mitochondrial protection |
| NMN / NAD+ Precursors | Supports cellular energy |
| CoQ10 | Antioxidant & heart health |
| Astaxanthin | Protects skin and eyes from oxidative stress |
| L-Theanine | Promotes relaxation and cognitive focus |
10. Applicable Industries & Use Cases
- Nutraceutical Brands: Cellular health & anti-aging formulas
- Cosmetic Manufacturers: Skin rejuvenation creams & serums
- Functional Food Companies: Longevity drink powders
- Pharma R&D Labs: Neuroprotection & autophagy studies
- Contract Manufacturers (OEM/ODM): Custom formulations with spermidine base
11. FAQ – Common Buyer Questions
Q1: What’s the natural source of AIHerba® Spermidine?
A1: Derived from non-GMO wheat germ and soybean fermentation using advanced microbial technology.
Q2: Is your Spermidine vegan and non-GMO?
A2: Yes, 100% vegan, non-GMO, and allergen-free.
Q3: Can I get a free sample for testing?
A3: Yes, we provide free samples (≤50g). Freight cost is covered by the buyer.
Q4: How do you ensure quality consistency between batches?
A4: Each batch undergoes HPLC assay verification and microbial safety testing with full traceability.
Q5: Do you provide OEM/ODM customization?
A5: Yes. We support private labeling, bulk formulation, and turnkey product solutions.
12. Reference Studies & Citations
- Eisenberg T. et al. Spermidine delays aging in humans and mice through autophagy induction. Nature Medicine, 2016. PubMed: 27841875
- Madeo F. et al. Spermidine in health and disease. Science, 2018. PubMed: 30093540
- FDA GRAS Notice for Spermidine Supplement Ingredient – FDA.gov
- NIH Office of Dietary Supplements – Polyamines Overview – NIH.gov
13. Why Choose AIHerba® as Your Spermidine Supplier
- ✅ 28+ years of extraction & fermentation experience
- ✅ GMP, ISO, HACCP certified factory
- ✅ Bulk supply & OEM/ODM customization
- ✅ Third-party tested purity ≥99%
- ✅ Free sample & fast global shipping
- ✅ Professional R&D support & technical documentation
AIHerba® – China Natural Plant Extracts Supplier & OEM Factory
Shaanxi Zhonghong Investment Technology Co., Ltd.
📧 sales@aiherba.com | info@aiherba.com | liaodaohai@gmail.com
🌐 www.aiherba.com
🏭 Factory Location: Xi’an, Shaanxi, China





