Resveratrol Extract – High-Purity Polygonum Cuspidatum Extract for Global B2B Manufacturers

1. Product Overview

Resveratrol is a natural polyphenolic compound extracted from Polygonum cuspidatum (Japanese Knotweed). Recognized for its antioxidant, anti-inflammatory, and healthy-aging properties, Resveratrol is widely used in dietary supplements, functional foods, cosmetics, and pharmaceuticals.
With more than 12 years of production experience, Shaanxi Zhonghong Investment Technology Co., Ltd. provides high-purity, consistent-quality Resveratrol backed by validated COA, analytical methods, and international export documentation.

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2. Product Origin

• Botanical Source: Polygonum cuspidatum Sieb. et Zucc.

• Plant Part Used: Root

• Extraction Method: Ethanol extraction → Purification → Crystallization

• Synonyms: 3,5,4′-Trihydroxystilbene

• CAS Number: 501-36-0

• Active Ingredient: Resveratrol (≥ 50% – 99% HPLC)

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3. Key Benefits & Mechanisms

(1) Powerful Antioxidant Protection

Resveratrol scavenges free radicals and inhibits lipid peroxidation, contributing to cellular protection and healthy aging.

(2) Supports Cardiovascular Health

Studies suggest improvements in endothelial function, circulation, and LDL oxidation resistance.

(3) Anti-Inflammatory Properties

Inhibits COX pathways and reduces inflammatory cytokines, supporting joint and metabolic well-being.

(4) Cellular Energy & Longevity Support

Activates SIRT1 pathways, linked with healthy aging, mitochondrial function, and energy metabolism.

(5) Skin Health & Anti-Aging

Common in premium cosmetic formulations for brightening, anti-wrinkle, and antioxidant protection.

Reference examples:

• PubMed: https://pubmed.ncbi.nlm.nih.gov/

• NIH Resveratrol Fact Sheet

• FDA GRAS Notices (when applicable)

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4. Traditional Use

Polygonum cuspidatum has been used in traditional Asian herbal medicine for:

• Clearing heat

• Supporting blood circulation

• Detoxification

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5. Recommended Dosage & Application Guidelines

Dietary Supplements

• Typical dosage: 50–500 mg/day

• Capsules, tablets, effervescent powders, gummies, beverages

Cosmetics

• Recommended addition: 0.1–1.0%

• Used in anti-aging serums, whitening creams, masks

Functional Foods

• 50–200 mg/serving depending on formulation target

Best Formulation Practices

1. Protect from light and oxygen.

2. Combine with lipids (MCT, phospholipids) for enhanced bioavailability.

3. Compatible synergistic partners: quercetin, vitamin C, grape seed extract.

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6. Safety & Precautions

• Not recommended for pregnant or breastfeeding women without professional guidance.

• Avoid high doses in individuals taking anticoagulants.

• Follow local regulatory limits for supplements and cosmetics.

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7. Product Specifications (COA Style Table)

7.1 Physical & Chemical Characteristics

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7.2 Pesticide Residues

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7.3 Heavy Metals

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7.4 Microbiological Tests

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8. Production Technology

8.1 Manufacturing Process

1. Raw material selection

2. Cleaning & crushing

3. Ethanol extraction

4. Concentration

5. Filtration

6. Purification

7. Crystallization

8. Drying

9. Milling & sieving

10. Final blending

11. QA sampling

12. Packaging

8.2 Quality Control

• HPLC assay for purity

• Microbiology checks

• Heavy metals and pesticides testing

• Stability and oxidation control

• Complies with USP, EP, GB standards

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9. Storage & Shelf Life

• Storage: Keep in a cool, dry place, away from light and moisture.

• Shelf Life: 24 months in original unopened packaging.

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10. Packaging Options

• Standard: 25 kg/drum

• Drum Material: Food-grade fiber drum with double PE liner

• Palletization: 27 drums/pallet

• Custom packaging available

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11. Sample Policy

• Free 20–50 g samples available

• Freight cost borne by customer or provided by courier account

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12. Transportation & Minimum Order Quantity

• MOQ: 1 kg

• Logistics: Air cargo, international express, sea freight

• Documents: COA, MSDS, TDS, commercial invoice, packing list, phytosanitary certificate (on request)

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13. Applicable Industries & Use Cases

Industries

1. Nutraceuticals & Dietary Supplements

2. Functional Food & Beverage

3. Cosmetics & Personal Care

4. Pharmaceutical Intermediate

5. Anti-aging & Sports Nutrition Formulations

Use Scenarios

• Anti-aging capsules

• Heart health formulations

• Beauty-from-within products

• Whitening & antioxidant skincare

• Functional drinks

• Gummies and effervescent tablets

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14. Case Studies

Case 1: EU Nutraceutical Brand

Upgraded to 98% resveratrol for a vegan capsule line, achieving 30% higher customer retention due to improved purity.

Case 2: Asian Whitening Serum Brand

Used 1% trans-resveratrol in a brightening formula, significantly reducing oxidation compared with their previous raw material.

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15. Certifications & Compliance

• ISO9001

• ISO22000 / HACCP

• Kosher

• Halal

• COA batch traceability

• Third-party testing (SGS/CNAS labs) available

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16. Frequently Asked Questions (FAQ)

1. Can you provide customized purity levels?

Yes. 50%, 98%, and 99% trans-resveratrol can be customized.

2. Do you support OEM/ODM formulation guidance?

Yes, including dosage design and synergistic ingredient suggestions.

3. Is your resveratrol safe for cosmetics?

Yes, it meets cosmetic-grade microbial and heavy metal limits.

4. What is your lead time?

Typically 3–7 working days after order confirmation.

5. Can you ship to the EU/US?

Yes, with all compliance documents required by customs.

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17. References

(Examples only; actual page would include itemized links.)

1. NIH National Library of Medicine – Resveratrol Research

2. PubMed Clinical Studies on Resveratrol

3. EFSA & FDA regulatory references regarding polyphenols

4. USP Standards for Herbal Extracts