Pyrroloquinoline Quinone (Pqq)
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AIHerba® Pyrroloquinoline Quinone – Certified Extract with COA & OEM Solutions

What Is Pyrroloquinoline Quinone (PQQ)? Benefits, Applications, Specifications & Bulk Supply Guide

  1. English Name: Pyrroloquinoline Quinone (PQQ)
  2. Specification: ≥ 98% (HPLC); available in water-soluble and oil-soluble forms for different supplement and beverage applications.
  3. Appearance: Reddish-orange crystalline powder with a clean, neutral odor.
  4. CAS No.: 72909-34-3
  5. Lead Time: 3–7 working days based on order volume and packaging requirements.
  6. Package: 25 kg/drum; 27 drums per pallet; custom small packaging available for R&D or pilot production.
  7. Main Market: Europe, North America, Asia; widely supplied to nutraceutical, functional beverage, sports nutrition, and healthy aging brands.
  8. Application / Key Benefits: Known for cellular energy support, mitochondrial biogenesis, cognitive performance, and antioxidant activity. Often used in brain-health, anti-fatigue, and longevity formulas.
  9. Industry Applications:
    a) Nutraceuticals – Capsules, tablets, powder blends, nootropic products.
    b) Functional Foods & Drinks – Energy drinks, wellness beverages, effervescent powders.
    c) Sports Nutrition – Endurance and recovery blends.
    d) Healthy Aging – Mitochondria-support and antioxidant formulas.
    e) R&D & Pharma – Used in studies related to oxidative stress and cellular metabolism.
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1. Pyrroloquinoline Quinone (PQQ) – High-Purity Botanical Extract | AIHerba®

AIHerba® offers high-purity Pyrroloquinoline Quinone (PQQ) extract, a potent bioactive compound with growing applications in functional foods, dietary supplements, cosmetics, and pharmaceutical health products. Sourced from premium natural plant fermentation, PQQ is manufactured under GMP-certified facilities, ensuring consistency, traceability, and industrial-scale supply. Our PQQ extract undergoes rigorous quality control, including heavy metal, pesticide residue, and microbial testing, making it ideal for B2B bulk purchasing and customized formulations. With over 28 years of experience in natural plant extraction, AIHerba provides OEM/ODM solutions, offering reliable sourcing for international buyers seeking scientifically validated ingredients. Contact us to acquire bulk PQQ with guaranteed purity, COA documentation, and professional technical support.

2. What is Pyrroloquinoline Quinone (PQQ)?

Pyrroloquinoline Quinone (PQQ) is a naturally occurring compound found in certain plant sources and produced via microbial fermentation. It is recognized for its antioxidant properties and involvement in cellular energy metabolism. PQQ is used globally as a functional ingredient in dietary supplements, energy formulations, and cosmetic actives.

3. Product Origin & Manufacturing Source

  • Origin: China, sourced from controlled fermentation of natural plant substrates

  • Factory: AIHerba® – GMP-certified, ISO 9001 and ISO 22000 compliant

  • Manufacturing Experience: Over 28 years in natural plant extraction and OEM/ODM production

4. Mechanism & Functional Benefits

While PQQ is not intended to diagnose, treat, or cure diseases, scientific studies highlight the following cellular and metabolic roles:

  1. Supports mitochondrial function and cellular energy metabolism.

  2. Exhibits antioxidant properties and neutralizes reactive oxygen species (ROS).

  3. Promotes the regeneration of coenzymes involved in redox reactions.

  4. Acts as a bioactive ingredient in dietary supplements, functional foods, and cosmetic formulations.

References:

5. Traditional Applications & Use Guidance

  • Applications: Nutraceuticals, functional foods, dietary supplements, cosmetics, pharmaceutical health products

  • Suggested Use: Typically incorporated at 1–20 mg per daily serving for dietary supplements (dosage depends on formulation)

  • Formulation Tips: Compatible with CoQ10, resveratrol, or multivitamin blends; water- and oil-soluble forms available

6. Product Specifications & COA

Parameter Type Name Specification Test Method
Active Ingredient Pyrroloquinoline Quinone ≥ 99% (HPLC) HPLC
Appearance – Reddish-brown crystalline powder Visual
Solubility – Water-soluble / ethanol-soluble Solubility Test
CAS Number – 72909-34-3 N/A
Moisture – ≤ 3% Loss on Drying

6.1 Pesticide Residue

Pesticide Limit Method
Total Pesticides ≤ 0.01 mg/kg GC-MS
Organochlorines ND GC-MS
Organophosphates ND GC-MS

6.2 Heavy Metals

Metal Limit Method
Lead (Pb) ≤ 0.5 mg/kg ICP-MS
Arsenic (As) ≤ 0.5 mg/kg ICP-MS
Cadmium (Cd) ≤ 0.1 mg/kg ICP-MS
Mercury (Hg) ≤ 0.1 mg/kg ICP-MS

6.3 Microbiological Tests

Microorganism Limit Method
Total Plate Count ≤ 1000 CFU/g AOAC 990.12
Yeast & Mold ≤ 100 CFU/g AOAC 997.02
E. coli ND AOAC 991.14
Salmonella ND AOAC 2003.03

7. Production Process

  1. Raw Material Selection: Verified plant substrates or fermentation media

  2. Fermentation: Controlled microbial production of PQQ

  3. Extraction: Water-ethanol or supercritical CO₂ extraction

  4. Purification: Multi-stage crystallization and filtration

  5. Quality Testing: HPLC purity, heavy metals, microbial tests

  6. Packaging: GMP-compliant packaging for bulk or OEM use

8. Storage & Shelf Life

  • Storage: Cool, dry place, away from light and moisture

  • Shelf Life: 24 months under recommended storage conditions

9. Packaging & Samples

  • Packaging: 25 kg/drum, 27 drums/tray (custom packaging available)

  • Sample Policy: Available upon request for testing and formulation

  • Minimum Order Quantity (MOQ): 1 kg for bulk orders

10. Clinical Data & Research Highlights

  • PQQ supports mitochondrial biogenesis and cellular energy metabolism (PubMed 14654816)

  • Research demonstrates antioxidant effects and potential applications in functional nutrition

  • Compatible with a range of dietary supplement and cosmetic formulations

11. Industry Applications & Usage Scenarios

  • Dietary Supplements: Energy formulas, multivitamins

  • Functional Foods & Beverages: Sports nutrition, wellness drinks

  • Cosmetics: Anti-aging and antioxidant skincare products

  • Pharmaceuticals: Health supplements, bioactive formulations

12. Factory Credentials & Quality Assurance

  • Certifications: GMP, ISO 9001, ISO 22000

  • Testing: Full COA provided for every batch

  • OEM/ODM Capabilities: Custom formulations, labeling, and packaging

13. FAQ (6 Questions)

  1. What is Pyrroloquinoline Quinone (PQQ)?
    PQQ is a naturally occurring bioactive compound produced via fermentation or extracted from plant sources.

  2. Is AIHerba® PQQ safe for B2B use in supplements?
    Yes, it is GMP-certified, heavy-metal tested, pesticide-free, and microbial compliant.

  3. What is the recommended dosage for functional foods?
    Typical use ranges from 1–20 mg per serving, depending on formulation requirements.

  4. Can PQQ be combined with other antioxidants?
    Yes, PQQ is compatible with CoQ10, resveratrol, and multivitamin blends.

  5. How is PQQ stored and what is its shelf life?
    Store in a cool, dry place; shelf life is 24 months.

  6. Does AIHerba provide samples and COA?
    Yes, samples and full COA are available for testing and evaluation.

14. References & Research Links

  1. PubMed: Pyrroloquinoline Quinone and Mitochondrial Function

  2. FDA: Dietary Supplement Ingredient Guidance

  3. NIH Research Overview: PQQ Studies

  4. AOAC Microbiological Testing Standards: AOAC Official Methods

15. Contact AIHerba®

AIHerba® | China Natural Plant Extracts Supplier & OEM Factory
Shaanxi Zhonghong Investment Technology Co., Ltd.
📧 sales@aiherba.com | info@aiherba.com | liaodaohai@gmail.com
🌐 www.aiherba.com

Experience, Authority, and Trust: AIHerba delivers high-quality, traceable Pyrroloquinoline Quinone extract for professional buyers worldwide, backed by scientific evidence, full COA, and GMP production standards.

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