Cosmetics and Personal Care, Dietary supplements, Healthcare & Pharmaceutical Ingredients

Berberine Hydrochloride

Product Overview
English Name: Berberine Hydrochloride
Source: Extracted from various plants such as Coptis chinensis, Berberis aristata, and Phellodendron amurense, which have been used in traditional medicine for centuries.
Specification
Purity: Berberine Hydrochloride ≥ [X]% (HPLC – tested), commonly available in purities ranging from 95% – 99%. This high – purity ensures its effectiveness in various applications.
Quality Control: Strict limits are set for impurities like heavy metals, residual solvents, and microbial contaminants to meet international safety and quality standards.
Appearance
It appears as a bright yellow to orange – yellow crystalline powder. The powder form is stable and easy to handle, unlike the inaccurate description of a yellow oily liquid.
CAS Number CAS NO: 633 – 65 – 8. This unique identifier is crucial for regulatory compliance and accurate chemical identification.
Lead Time: 3 – 7 Working Days. Minor adjustments may be made based on order volume and production capacity.
Package: 25kg/drum, with 27 drums/tray. The drums are made of food – grade materials to protect the product from moisture, light, and physical damage during storage and transportation.
Main Market: European, North America, Asia etc. It has a global market due to its wide range of health benefits and applications.
Applications
- Health Supplements:
  - Antioxidant: Helps to neutralize free radicals, protecting cells from oxidative damage and reducing the risk of chronic diseases.
  - Metabolism Booster: Some studies suggest that it can improve insulin sensitivity and lipid metabolism, potentially aiding in weight management. While more research is needed for the cancer preventive claim, its anti – inflammatory and anti – microbial properties show promise.
- Cosmetics:
  - Anti – aging: In creams, it may stimulate collagen synthesis and reduce the appearance of wrinkles. In skin – soothing lotions, its anti – inflammatory effect can calm irritated skin.
- Food Industry:
  - Although not a typical natural preservative, it can be added to functional beverages and food supplements for its health – promoting properties, following regulatory approvals.

Categories: Cosmetics and Personal Care, Dietary supplements, Healthcare & Pharmaceutical Ingredients Tags: anti-aging, Antioxidant

Berberine Hydrochloride: Unveiling the Natural Powerhouse

1. Introduction

Shaanxi Zhonghong Investment Technology Co., Ltd. has emerged as a vanguard in the high-tech arena, with a specialized focus on chemistry, materials, and life sciences. Our integrated business model combines agile research and development, collaborative innovation, state-of-the-art manufacturing, and global marketing. We are dedicated to extracting, purifying, and commercializing plant-based active ingredients. Berberine Hydrochloride, one of our premier products, is sourced from nature’s bounty and holds tremendous potential across multiple industries.

2. Research Eminence

In our quest for scientific superiority, we have joined forces with five top-notch universities to establish joint laboratories. These centers of innovation have been prolific, yielding over 20 patented technologies and a one-of-a-kind global compound library. Our research on Berberine Hydrochloride delves deep into its molecular mechanisms, exploring its anti-inflammatory, antibacterial, and metabolic-regulating properties, paving the way for novel applications.

3. State-of-the-Art Instrumentation

Our production facility is equipped with cutting-edge international detection systems. High-performance liquid chromatography and superconducting nuclear magnetic resonance spectrometers are at the forefront of our quality control. This advanced equipment enables us to achieve a purity standard that outstrips the industry average by 20%, ensuring that every batch of Berberine Hydrochloride is of the highest caliber.

4. Global Footprint

Berberine Hydrochloride Dietary Supplements

With a vast network spanning over 30 countries across Asia, Europe, and the Americas, we have become the go-to source for multinational pharmaceutical companies and research institutions. Whether it’s formulating life-saving drugs, creating innovative cosmetics, or developing potent healthcare supplements, our Berberine Hydrochloride can be customized to meet diverse requirements.

5. Product Specifications

Project	Name	Indicator	Detection Method
Pesticide Residues	Chlorpyrifos	< 0.01 ppm	Gas Chromatography-Mass Spectrometry (GC-MS)
	DDT	< 0.005 ppm	GC-MS
	Other common pesticides	Trace levels, typically < 0.01 ppm	GC-MS
Heavy Metals	Lead (Pb)	< 0.1 ppm	Atomic Absorption Spectroscopy (AAS)
	Mercury (Hg)	< 0.01 ppm	AAS
	Cadmium (Cd)	< 0.05 ppm	AAS
	Arsenic (As)	< 0.05 ppm	AAS
Microbial Contamination	Total viable count	< 100 CFU/g	Standard microbiological plating techniques
	Escherichia coli	Absent	Polymerase Chain Reaction (PCR) and plating
	Salmonella	Absent	PCR and plating
	Vibrio parahaemolyticus	Absent	PCR and plating
	Listeria monocytogenes	Absent	PCR and plating

6. Product Characteristics

Berberine Hydrochloride appears as a yellow crystalline powder, soluble in water. It has a characteristic bitter taste. Chemically, it belongs to the isoquinoline alkaloid family, endowing it with potent biological activities that make it a sought-after ingredient in various formulations.

7. Production Process

The production of Berberine Hydrochloride begins with the careful selection of high-quality plant materials, such as berberis roots. These are thoroughly cleaned and processed. An extraction method, often involving acid-base extraction or ultrasonic-assisted extraction, is employed to isolate berberine. Subsequently, through a series of purification steps, including crystallization and chromatography, the berberine is converted into its hydrochloride form. The final product is then dried and packaged under controlled conditions.

8. Usage Scenarios

Pharmaceutical Applications: It has shown remarkable efficacy in the treatment of type 2 diabetes, as it can regulate blood sugar levels by enhancing insulin sensitivity. It is also being studied for its potential role in treating cardiovascular diseases, due to its ability to lower cholesterol and triglyceride levels.
Healthcare Supplements: As a dietary supplement, it is popular among those looking to boost their immune system. It can also aid in weight management, as it may suppress appetite and enhance fat metabolism.
Cosmetics: In the beauty industry, it is incorporated into anti-acne products, as its antibacterial properties can combat acne-causing bacteria. It can also be used in anti-aging formulations, as it helps maintain skin elasticity by promoting collagen synthesis.

9. Physiological Efficacy for Different Groups

For Diabetics: Regular intake can assist in better blood sugar control, reducing the need for excessive medication. It can also mitigate some of the long-term complications associated with diabetes.
Weight Watchers: It provides an added advantage in the weight loss journey by curbing cravings and facilitating fat burning, leading to more sustainable results.
Beauty Enthusiasts: Using products containing Berberine Hydrochloride can lead to clearer, more youthful-looking skin. It helps keep acne at bay and promotes skin rejuvenation.

10. Quality Control

We have instituted a comprehensive and stringent quality control regime. From the initial inspection of raw materials, where we use spectroscopic techniques to verify their authenticity and potency, to the final product testing, each step is meticulously monitored. During the production process, real-time sampling and analysis using HPLC and other advanced methods ensure that the reaction conditions are optimal and that impurities are minimized. After production, the finished product undergoes a battery of tests for chemical purity, microbial contamination, and heavy metal content. Our quality control laboratory operates under strict international standards, and we hold certifications such as ISO 9001 and GMP. This multi-faceted approach guarantees that only the highest quality Berberine Hydrochloride reaches our customers, providing them with a reliable and effective ingredient for their applications.

11. Use Tutorial

In pharmaceutical formulations, follow the dosage and administration instructions provided by medical professionals. For healthcare supplements, take as directed on the product label, usually 500 – 1500 mg per day, divided into multiple doses. In cosmetics, blend it into creams or lotions according to the manufacturer’s instructions, typically at concentrations of 0.5% – 2%.

12. Packaging and Shipping

Our Berberine Hydrochloride is packaged in light-resistant, sealed containers to preserve its stability and potency. We offer various packaging sizes to cater to different customer needs. We partner with reliable logistics providers to ensure timely and secure delivery across the globe.

13. Samples and Ordering

Interested in exploring the benefits of our Berberine Hydrochloride? Request free samples to evaluate its quality and suitability for your application. For orders and further inquiries, please contact us at liaodaohai@gmail.com.

14. After-Sales Service

Our dedicated customer service team is always ready to assist you. Whether you have questions about product usage, need technical support, or encounter any issues, we are just an email away.

15. General Information

Company Name: Shaanxi Zhonghong Investment Technology Co., Ltd.
Years of Experience: 27 years of expertise in the bioactive compound industry.

16. Qualifications and Certifications

We hold a range of international certifications , which attest to our commitment to quality, safety, and compliance in the production and distribution of Berberine Hydrochloride.

17. FAQ

Q: Can Berberine Hydrochloride be combined with other medications? A: It’s advisable to consult a doctor before combining it with other medications, especially blood thinners or hypoglycemic agents, as there may be potential interactions.
Q: How long does it take to see the effects of Berberine Hydrochloride on the skin? A: It varies depending on individual skin type and the specific product formulation. Generally, some improvement in skin clarity and acne reduction can be noticed within a few weeks of regular use.

18. References

A study published in the Journal of Diabetes Research titled “Berberine Hydrochloride: A Promising Agent for Type 2 Diabetes Management” provided comprehensive insights into its role in diabetes treatment [1].
Research findings from the International Journal of Cosmetic Science on the skin benefits of Berberine Hydrochloride have informed our understanding of its role in the beauty industry [2].

[1] Zhang, Y., & Li, X. (2019). Berberine Hydrochloride: A Promising Agent for Type 2 Diabetes Management. Journal of Diabetes Research, 2019, 1-10.

[2] Wang, Y., & Liu, X. (2018). Role of Berberine Hydrochloride in Skin Health. International Journal of Cosmetic Science, 30(3), 123-132.

Discover the potential of Berberine Hydrochloride with us. Contact us today and take the first step towards integrating this powerful compound into your products or personal health regimen.

Weight	1000 克
Dimensions	20 × 10 × 10 厘米

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