Bulk Hyaluronic Acid Guide: Purity, Specs & Industrial Sourcing
,

Hyaluronic Acid Manufacturer | Bulk Wholesale & Global Supply

  1. Product Name: Hyaluronic Acid (Sodium Hyaluronate) | Industrial Bulk Supply

  2. Assay (HPLC): ≥ 99.0% (Certified Glucuronic Acid ≥ 45.0%)

  3. Appearance: White Crystalline Powder / Granules (Uniform Particle Size)

  4. CAS No.: 9067-32-7

  5. Solubility: 100% Water-Soluble (Transparent Viscous Solution)

  6. Stability: High Thermal Stability; Optimal between pH 5.0 – 8.5

  7. Lead Time: 3–7 Working Days (Global Bulk Stock)

  8. Packaging: 25kg Standard Drum / 1kg Sample Available

  9. Compliance: GMP Certified / Full Batch COA & TDS Provided

  10. Application: Professional Nutricosmetics, Medical Aesthetics & OEM/ODM

Bulk Supply & Technical Advisory
🛡️
GMP Certified
🔬
HPLC Lab Tested
🌍
Global Logistics
📦
Free Samples

01. Hyaluronic Acid Bulk Supplier — Procurement Summary

Manufacturer: AIHerba®
Grade: Pharma / Cosmetic / Food
Supply Form: Sodium Hyaluronate Powder
MOQ: 1kg (R&D) / 25kg (Industrial)
Lead Time: 3–7 Business Days
COA: Batch-Specific Available
Packaging: 25kg Fiber Drum
Export: Global B2B Supply Hubs

02. Manufacturer & Quality Assurance Platform

AIHerba® Manufacturing Hub

Operated by Shaanxi Zhonghong Investment Technology Co., Ltd., our platform integrates upstream fermentation control with downstream analytical release. We operate under strict GMP protocols to ensure zero-risk supply for global brands.

✔ GMP System
✔ Batch Traceability
✔ Raw Material Control
✔ Analytical Release

03. Hyaluronic Acid Identity Profile

Parameter Industrial Specification
Chemical Name Sodium Hyaluronate (HA-Na)
CAS Number 9067-32-7 (Sodium Salt) / 9004-61-9 (Acid)
Molecular Weight Customized (3k Da – 3.0M Da)
Source Non-Animal Bio-fermentation (Streptococcus zooepidemicus)
Appearance White or Off-White Powder / Granules

04. Technical Specification & Release Standard

PURITY (HA-NA)

≥ 99.0%
GLUCURONIC ACID

≥ 45.0%
HEAVY METALS

≤ 10 ppm
PH (0.1% SOL.)

5.0 – 8.5
LOSS ON DRYING

≤ 10.0%
RESIDUAL PROTEIN

≤ 0.05%
MICROBIAL COUNT

≤ 100 cfu/g
SHELF LIFE

24 Months

05. Analytical Verification & Scientific Fingerprint

Our laboratory utilizes high-precision instrumentation to verify structural habit and molecular distribution. Every industrial batch is released only after passing the following analytical hurdles:

SEC-GPC
MW Distribution
HPLC-UV
Assay & Impurity
ICP-MS
Trace Elements
USP <61/62>
Microbial Safety

* Illustrative Technical Simulation: Typical batch release profile using international pharmacopeia methods.

06. Batch Release & Quality Control System

01
Raw Material Inspection
02
Fermentation Control
03
Purification Process
04
Laboratory Testing
05
Batch Release

08. Molecular Structure & Functional Characteristics

Hyaluronic Acid is a linear polysaccharide composed of repeating disaccharide units of D-glucuronic acid and N-acetyl-D-glucosamine. Its industrial efficacy is determined by its Viscoelasticity and Hydration Capacity. High Molecular Weight (HMW) variants provide superior film-forming and moisture retention, while Low Molecular Weight (LMW) and Oligo-HA variants are engineered for deep dermal penetration and cellular signaling support.

09. Industrial Application Compatibility

Cosmetic Formulation

Functional properties in serums, creams, and masks for moisture barrier support.

Nutraceuticals

Ingestible grades for joint lubrication and “Beauty-from-Within” supplement protocols.

Medical Materials

Specialized high-viscosity grades for visco-supplementation research and wound-care dressings.

10. Formulation Development Guide

Solubility & Hydration

Highly water-soluble. To prevent “fish-eyes” or clumping, it is recommended to disperse in glycerin or use high-shear mixing for rapid hydration.

pH Compatibility

Optimally stable between pH 5.0 – 8.5. Avoid extreme acidic conditions which trigger polymer chain scission and viscosity loss.

16. Market Benchmark Comparison

Metric Standard Market Supply AIHerba® Industrial Platform
Assay Verification Generic Lab Report SEC-GPC + NMR Verification
Traceability Broker-Level Full Batch-Lot Control
Residual Control Standard Compliance Ultra-Low Protein < 0.05%
Technical Support Sales Only Direct Engineering Consultation

17. Technical Procurement FAQ

What molecular weight options are available for industrial scale?
AIHerba® provides the full spectrum: Oligo (<10k Da), Low (10k-500k Da), Medium (500k-1.5M Da), and Ultra-High (>2.5M Da). We can customize molecular weight ranges to match your specific viscosity requirements.
How do you verify the bacterial endotoxin levels for medical grades?
For pharmaceutical and injectable research grades, we utilize LAL (Limulus Amebocyte Lysate) testing to ensure levels are <0.05 IU/mg, compliant with USP <85>.
Is the Sodium Hyaluronate non-GMO and Vegan certified?
Yes. Our fermentation process uses non-GMO bacteria and plant-derived substrates. It is 100% free from animal precursors, making it suitable for Vegan and Clean Label certifications.
What analytical method do you use to measure molecular weight?
We utilize Size Exclusion Chromatography coupled with Multi-Angle Laser Light Scattering (SEC-MALLS), which is the most accurate method for determining absolute molecular weight and polydispersity index (PDI).
What is the storage stability for bulk drums?
Under standard conditions (cool, dry, sealed), HA is stable for 24 months. We use dual-layer PE liners and argon-flushing for bulk drums to prevent oxidative degradation during transit and storage.

18. AIHerba Industrial Quality Commitment

✓ GMP Manufacturing
✓ Batch Traceability
✓ Analytical Release
✓ Technical Dossier
✓ OEM Support
✓ Global Export


Bulk Supply & Technical Advisory
🛡️
GMP Certified
🔬
HPLC Lab Tested
🌍
Global Logistics
📦
Free Samples
Scroll to Top

Request Factory-Direct Quote & Lab Samples

Access our 29-year R&D database. Batch-specific HPLC Fingerprints, COA & MSDS included. Standard samples dispatched via FedEx/DHL within 48h.

Request Factory-Direct Quote & Lab Samples