1. Pharmaceutical Grade Sodium Hyaluronate Supplier | Bulk GMP Certified Sodium Hyaluronate Manufacturer
AIHerba® is a GMP-certified manufacturer of Pharmaceutical Grade Sodium Hyaluronate, offering bulk supply for pharmaceutical applications. Our product is widely used in injectable formulations, moisturizers, and other pharmaceutical products, offering custom molecular weight options and high-purity standards. With over 28 years of expertise, AIHerba® ensures molecular consistency and regulatory compliance in every batch.
Our GMP-certified facilities guarantee traceable production and complete COA and MSDS documentation, making us the ideal partner for pharmaceutical companies and OEM manufacturers seeking bulk Sodium Hyaluronate for their formulations.
👉 Request bulk pricing, technical specifications, or samples today.
2. What Is Pharmaceutical Grade Sodium Hyaluronate?
Pharmaceutical Grade Sodium Hyaluronate is a high-purity form of hyaluronic acid (HA), commonly used in pharmaceutical applications. This sodium salt of hyaluronic acid is known for its exceptional water-binding properties, which make it ideal for use in injectables and other pharmaceutical formulations. Sodium Hyaluronate is also essential in products like moisturizing creams, serums, and anti-aging treatments.
Unlike its non-pharmaceutical counterpart, pharmaceutical-grade Sodium Hyaluronate is produced under strict quality controls to meet GMP standards and ensure molecular stability and safety for use in injectable and other critical formulations.
3. Detailed Technical Specifications
3.1 Basic Technical Parameters
| Item | Specification |
|---|---|
| Product Name | Pharmaceutical Grade Sodium Hyaluronate |
| CAS Number | 9067-32-7 |
| Appearance | White to off-white powder |
| Solubility | Freely soluble in water |
| Molecular Weight | Customizable (Low / Medium / High) |
| Assay (HA Content) | ≥ 95% |
| pH (0.5% Solution) | 5.0 – 8.5 |
| Loss on Drying | ≤ 10% |
3.2 Molecular Weight Options
| Molecular Weight Range | Application |
|---|---|
| Low MW (5–50 kDa) | Injectable solutions, serums |
| Medium MW (100–500 kDa) | Anti-aging, injectable products |
| High MW (800–2000 kDa) | Deep moisturizing, injectable treatments |
(Target keywords: Pharmaceutical Grade Sodium Hyaluronate, Bulk Supply, Injectable Use)
4. Product Source & Raw Material Origin
AIHerba®’s Pharmaceutical Grade Sodium Hyaluronate is produced through microbial fermentation, ensuring non-animal-derived purity. The raw materials are sourced from high-quality, environmentally sustainable substrates. Each batch is fully traceable from raw material to final product, guaranteeing high purity, consistency, and safety.
Our GMP-certified facilities strictly monitor and test every production step, ensuring compliance with global regulatory standards.
5. Mechanism of Action & Functional Properties
Sodium Hyaluronate acts as an effective humectant, attracting moisture from the surrounding environment and locking it into the skin. This leads to long-lasting hydration and improved skin elasticity.
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Water-binding capacity: Retains moisture, reducing dryness and improving skin texture.
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Viscoelastic properties: Enhances skin smoothness and elasticity.
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Hydration and anti-aging: May reduce fine lines and improve skin tone.
(Non-medical claims, complies with YMYL guidelines)
6. Application-Relevant Benefits (Regulatory-Safe)
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Hydration: Helps skin retain moisture for long-lasting hydration.
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Smooth Texture: Improves skin texture, making it feel softer and more supple.
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Elasticity: Supports skin elasticity, reducing fine lines and wrinkles.
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Formulation Stability: Enhances texture and prolongs the shelf life of pharmaceutical products.
These benefits make Sodium Hyaluronate essential in pharmaceutical formulations aimed at improving skin hydration, texture, and appearance.
7. Usage Guidelines & Formulation Recommendations
| Application | Recommended Usage Level |
|---|---|
| Injectable Solutions | 0.1% – 0.5% |
| Facial Serums | 0.05% – 0.5% |
| Anti-aging Treatments | 0.1% – 0.5% |
| Moisturizing Creams | 0.1% – 0.3% |
Formulation Tips:
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Pre-dissolve in water to ensure smooth mixing and stability.
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Avoid excessive heat (>60°C) during processing to maintain the integrity of Sodium Hyaluronate.
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Select molecular weight based on intended use, such as lower molecular weights for injectables and higher for topical formulations.
8. Traditional & Modern Industrial Applications
Sodium Hyaluronate is used in a variety of pharmaceutical and cosmetic applications:
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Injectables: Sodium Hyaluronate is used in dermal fillers and joint injections for its moisture-retention and viscoelasticity properties.
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Topical Products: Used in anti-aging creams, serums, and moisturizing formulations.
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Medical Applications: Sodium Hyaluronate is increasingly used in wound healing and ophthalmic treatments.
9. COA & Quality Control Specifications
9.1 Pesticide Residue Control
| Item | Limit | Test Method |
|---|---|---|
| Organophosphates | ≤ 2 ppm | GC-MS |
| Organochlorines | ≤ 1 ppm | GC-MS |
| Pyrethroids | ≤ 1 ppm | GC-MS |
9.2 Heavy Metals
| Item | Limit | Test Method |
|---|---|---|
| Lead (Pb) | ≤ 2 ppm | ICP-MS |
| Arsenic (As) | ≤ 1 ppm | ICP-MS |
| Cadmium (Cd) | ≤ 1 ppm | ICP-MS |
| Mercury (Hg) | ≤ 0.1 ppm | ICP-MS |
9.3 Microbiological Limits
| Item | Limit | Test Method |
|---|---|---|
| Total Plate Count | ≤ 1,000 CFU/g | USP <61> |
| Yeast & Mold | ≤ 100 CFU/g | USP <61> |
| E. coli | Not detected | USP <62> |
| Salmonella | Not detected | USP <62> |
10. Manufacturing Process & Production Flow
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Microbial Fermentation: High-quality, non-animal substrates for fermentation.
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Purification: Advanced filtration to ensure maximum purity.
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Concentration: Reducing excess solvents to increase active ingredient concentration.
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Drying & Milling: Formulation of powder for ease of use in formulations.
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Quality Control: Rigorous testing of each batch to meet GMP standards.
11. Storage, Shelf Life & Packaging
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Storage: Store in a cool, dry place, away from light and moisture.
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Shelf Life: 24 months (unopened).
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Packaging: Available in 1 kg, 5 kg, or 25 kg sealed bags to maintain product stability.
12. MOQ, Sample Policy & Global Shipping
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MOQ: 1 kg for samples; 25 kg for bulk orders.
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Sample Policy: Free samples available for qualified buyers.
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Shipping: Air, sea, and express shipping options available worldwide.
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Lead Time: Typically 3–7 working days for stock products; 10–15 days for custom specifications.
13. Clinical Data & Scientific Research
Studies on Sodium Hyaluronate have demonstrated its moisturizing effects, anti-aging properties, and enhanced skin texture:
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Skin Hydration & Anti-aging Effects (PubMed)
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Impact of Molecular Weight on Absorption (NIH)
These studies are for informational purposes and are not intended to make medical claims.
14. Applicable Industries
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Pharmaceuticals
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Cosmetics
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Personal Care
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OEM/ODM Manufacturing
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Nutraceuticals
15. Industry Application Scenarios
Scenario 1: Injectable Solutions Manufacturer
Used in dermal fillers and joint injections to provide hydration and restore volume.
Scenario 2: Anti-aging Serum Manufacturer
Used in anti-aging formulations for its moisturizing and skin-plumping properties.
Scenario 3: OEM/ODM Manufacturer
Provides customized molecular weight Sodium Hyaluronate for skincare and pharmaceutical brands.
16. Supplier Comparison & Procurement Guide
| Factor | AIHerba® | Competitor |
|---|---|---|
| GMP Certified | ✔ | ❌ |
| Custom Molecular Weight Options | ✔ | Limited |
| Full COA & MSDS | ✔ | ❌ |
| Batch Traceability | ✔ | ❌ |
| MOQ for Bulk Orders | 25 kg | 50 kg+ |
17. FAQ for B2B Buyers
Q1: What is the MOQ for bulk orders?
MOQ is 1 kg for samples and 25 kg for bulk orders.
Q2: Is Sodium Hyaluronate animal-free?
Yes, it is produced through microbial fermentation, making it non-animal derived.
Q3: Can you provide COA and MSDS?
Yes, we offer full COA, MSDS, and technical documentation for every batch.
Q4: Do you offer OEM/ODM services?
Yes, we provide OEM/ODM solutions and customization based on client needs.
Q5: What is the shelf life of your product?
The shelf life is 24 months when stored properly in a cool, dry place.
Q6: How can I get a sample?
You can request free samples by contacting our sales team.
18. References & Regulatory Sources
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PubMed: https://pubmed.ncbi.nlm.nih.gov
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NIH: https://www.nih.gov
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FDA: https://www.fda.gov
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Cosmetic Ingredient Review: https://www.cir-safety.org
Manufacturer & Quality Assurance
Manufactured by AIHerba® (Shaanxi Zhonghong Investment Technology Co., Ltd.),
a GMP-certified manufacturer specializing in high-purity botanical extracts
for dietary supplements, cosmetics, and pharmaceutical applications.
✔ GMP-certified production facility
✔ Full COA & technical specifications available
✔ Batch traceability & strict quality control
✔ Bulk supply & OEM/ODM services for global B2B buyers
📧 sales@aiherba.com
📧 info@aiherba.com
📧 liaodaohai@gmail.com
🌐 www.aiherba.com
