Paclitaxel Bulk API: High-Purity Anticancer Ingredient for Pharmaceutical Formulations
1. Paclitaxel Bulk Supply | Premium Quality Natural Extract for Pharmaceutical & Cosmetic Use
AIHerba® | Leading Supplier & OEM Factory of Natural Plant Extracts
AIHerba (Shaanxi Zhonghong Investment Technology Co., Ltd.) is a GMP-certified manufacturer specializing in high-purity natural plant extracts. With over 28 years of R&D and production experience, we provide bulk and wholesale Paclitaxel (Taxol) for pharmaceutical, nutraceutical, and cosmetic applications. Our manufacturing facility integrates advanced extraction technologies, including supercritical CO₂ extraction, water-ethanol extraction, and microbial fermentation, ensuring high potency, stability, and purity. As a trusted partner for global businesses, we offer OEM & ODM services to deliver custom herbal formulations, natural flavors, and food & beverage additives.
Whether you’re sourcing pharmaceutical-grade raw materials, cosmetic actives, or nutraceutical ingredients, AIHerba guarantees consistent product quality, fast delivery, and transparent supply chains directly from China’s top natural plant extract factory.
For inquiries, bulk orders, and customized formulations:
📧 sales@aiherba.com | info@aiherba.com | liaodaohai@gmail.com
🌐 www.aiherba.com
2. What is Paclitaxel?
Paclitaxel is a powerful plant-derived anti-cancer agent isolated from the bark of the Pacific yew tree (Taxus brevifolia). It is primarily used in chemotherapy regimens for treating cancers such as breast, ovarian, and lung cancer. By stabilizing microtubules and preventing their disassembly, Paclitaxel inhibits cell division, effectively slowing down or stopping the growth of cancer cells.
As a naturally derived compound with demonstrated efficacy, it is also finding increasing application in the cosmetic industry due to its anti-inflammatory properties, making it useful in anti-aging formulations.
3. Technical Specifications
| Parameter | Specification | Test Method |
|---|---|---|
| Purity | ≥ 98% | HPLC |
| Appearance | White to Off-White Powder | Visual Inspection |
| Molecular Formula | C47H51NO14 | N/A |
| Molecular Weight | 853.91 g/mol | N/A |
| CAS Number | 33069-62-4 | N/A |
| Solubility | Soluble in ethanol, DMSO | Solubility Test |
4. Mechanism of Action & Health Benefits
Mechanism of Action:
Paclitaxel is an antimitotic agent that binds to microtubules and prevents their depolymerization, thereby blocking cell division and leading to programmed cell death (apoptosis). This makes it highly effective in treating various cancers.
Health Benefits:
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Anti-Cancer: Paclitaxel is most commonly used in the treatment of solid tumors, particularly in breast and ovarian cancers. It has also shown promise in lung and other cancers.
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Skin Regeneration: In cosmetics, Paclitaxel is gaining recognition for its ability to reduce inflammation and promote skin healing, making it ideal for anti-aging formulations.
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Immune System Support: While used primarily in chemotherapy, Paclitaxel may help enhance the immune system’s ability to combat cancerous cells.
5. Usage Guidelines & Recommended Dosage
Pharmaceutical Use:
Typically administered intravenously in clinical settings, the usual dosage of Paclitaxel for chemotherapy treatment is 135–175 mg/m² every 3 weeks, depending on the specific cancer being treated and the patient’s individual response.
Cosmetic Use:
For skin care applications, Paclitaxel can be incorporated into topical anti-aging products. A typical concentration ranges from 0.01% to 0.1%, depending on the product’s formulation and desired effects.
Recommended Dosage:
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Oral Supplementation (for research or specialized formulations): 0.1–5 mg per day, under professional guidance.
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Topical Application: 0.01% to 0.1% concentration for anti-aging skin care.
6. Traditional Applications & Industry Use Cases
Pharmaceutical Applications:
Paclitaxel is used extensively in chemotherapy to treat a variety of cancers. It remains one of the most effective agents in combination regimens for solid tumors.
Cosmetic Applications:
In skincare, Paclitaxel’s anti-inflammatory properties help reduce redness and irritation while promoting skin regeneration, making it an excellent choice for anti-aging creams and serums.
Other Applications:
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Research & Development: Paclitaxel is studied in various clinical trials for new cancer treatments.
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Bio-pharmaceutical Manufacturing: Used as a key ingredient in the production of oncology drugs.
7. Product Specifications, COA, and Quality Assurance
| Test Item | Specification | Test Method |
|---|---|---|
| Residual Pesticides | ≤ 0.01 mg/kg | HPLC |
| Lead (Pb) | ≤ 0.5 mg/kg | Atomic Absorption Spectroscopy |
| Cadmium (Cd) | ≤ 0.1 mg/kg | Atomic Absorption Spectroscopy |
| Mercury (Hg) | ≤ 0.05 mg/kg | Atomic Absorption Spectroscopy |
| Microbial Count | ≤ 100 CFU/g | USP Method |
| Yeast & Mold | ≤ 50 CFU/g | USP Method |
8. Manufacturing Process & Production Flow
AIHerba uses state-of-the-art manufacturing techniques to produce Paclitaxel with the highest purity and quality standards. The production process includes:
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Raw Material Sourcing: Paclitaxel is sourced from carefully selected Pacific yew trees, ensuring sustainability and quality.
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Supercritical CO₂ Extraction: This method ensures high purity and minimal environmental impact.
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Purification: Advanced purification techniques ensure the highest concentration of active compounds.
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Quality Control: Every batch undergoes rigorous testing to meet our strict quality standards.
9. Storage, Shelf Life, Packaging, and MOQ
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Storage: Store in a cool, dry place away from direct sunlight.
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Shelf Life: 2 years from the manufacturing date when stored under recommended conditions.
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Packaging: 25kg drums, customizable packaging available upon request.
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MOQ: 1 kg for bulk orders, samples available upon request.
10. Clinical Data & Latest Research
Recent studies have shown that Paclitaxel remains a critical drug in oncology, especially in combination therapies. Its use in cosmetic formulations is being explored for its ability to improve skin texture, reduce wrinkles, and enhance overall skin health.
11. Applicable Industries & Use Case Scenarios
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Pharmaceutical Industry: Paclitaxel is used in the formulation of chemotherapy drugs to treat breast, ovarian, and lung cancer.
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Cosmetic Industry: Paclitaxel’s anti-inflammatory and skin regeneration properties make it suitable for anti-aging creams and serums.
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Nutraceutical Industry: Paclitaxel is used in various supplement formulations aimed at boosting immune health and promoting anti-aging effects.
12. B2B Purchase & Procurement Guide
For global B2B buyers, AIHerba offers the following benefits:
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Bulk Orders: Competitive pricing with high-volume discount options.
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Custom Formulations: OEM/ODM services to meet specific product and packaging requirements.
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Certifications: Full COA, GMP, ISO certification, and detailed testing reports for quality assurance.
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Reliable Supply Chain: Guaranteed consistent supply and fast delivery.
13. FAQs for B2B Buyers
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What is the minimum order quantity (MOQ) for bulk purchases?
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MOQ is 1 kg for Paclitaxel.
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Can I get a sample before placing a large order?
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Yes, we offer free samples for testing.
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How is Paclitaxel packaged?
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Paclitaxel is packaged in 25kg drums, with customizable packaging available.
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What certifications do you offer?
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We offer GMP, ISO, and COA certifications with every batch.
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Do you provide custom formulations?
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Yes, we offer OEM/ODM services to suit your specific requirements.
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What is the shelf life of your Paclitaxel product?
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The shelf life is 2 years from the manufacturing date when stored properly.
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14. References
15. Manufacturer & Quality Assurance
Manufactured by AIHerba® (Shaanxi Zhonghong Investment Technology Co., Ltd.), a GMP-certified manufacturer specializing in high-purity botanical extracts for dietary supplements, cosmetics, and pharmaceutical applications.
✔ GMP-certified production facility
✔ Full COA & technical specifications available
✔ Batch traceability & strict quality control
✔ Bulk supply & OEM/ODM services for global B2B buyers
Bulk Supply & Technical Support
Get direct factory quotes, COA, and MSDS within 12 hours. We support bulk supply and custom specifications.





