Liquorice Glabridin: Premium Bioactive Extract for Global Health & Beauty Solutions
By Shaanxi Zhonghong Investment Technology Co., Ltd.

---

1. Product Overview

Liquorice Glabridin, a potent flavonoid isolated from Glycyrrhiza glabra (licorice root), is a high-performance ingredient renowned for its antioxidant, anti-inflammatory, and skin-brightening properties. With a purity level of ≥98% (HPLC-verified), this bioactive compound is ideal for pharmaceutical, cosmetic, and nutraceutical formulations. Its molecular structure (C20H20O4) enables targeted modulation of cellular pathways, making it a versatile solution for modern health challenges.

---

2. Company Profile

Shaanxi Zhonghong Investment Technology Co., Ltd. is a high-tech enterprise specializing in agile R&D, integrated manufacturing, and global distribution of plant-derived bioactive compounds. For over 28 years, we have pioneered innovations in:

• Extraction & Purification: Advanced techniques for isolating phytochemicals (e.g., supercritical CO₂ extraction).

• Applications: Customized ingredients for cosmetics, pharmaceuticals, and functional foods.

• Global Reach: Serving 80+ countries across Asia, Europe, and the Americas.

Key Competitive Advantages:

• R&D Excellence: 20+ patents and exclusive compound libraries developed with 5 top-tier universities.

• Cutting-Edge Equipment: HPLC, NMR, and ICP-MS systems ensuring 20% higher purity than industry standards.

---

3. Source & Sustainability

• Botanical Origin: Ethically sourced licorice roots from Xinjiang, China (organic-certified farms).

• Extraction Method: Proprietary ultrasonic-assisted supercritical CO₂ extraction minimizes environmental impact.

• Traceability: Blockchain-enabled supply chain tracking from farm to final product.

  

---

4. Liquorice Glabridin Health Benefits

• Skin Brightening: Inhibits tyrosinase activity (IC₅₀: 0.8 μM), reducing melanin synthesis.

• Anti-Aging: Neutralizes free radicals (ORAC value: 18,000 μmol TE/g) to combat oxidative stress.

• Metabolic Support: Activates PPAR-γ receptors to enhance insulin sensitivity.

• Anti-Inflammatory: Suppresses NF-κB and COX-2 pathways (EC₅₀: 12 μM).

---

5. Liquorice Glabridin Usage Guidelines

---

6. Precautions

• Storage: Keep in airtight containers at -20°C (shelf life: 24 months).

• Safety: Non-irritating at ≤2% concentration (OECD TG 439 certified).

• Contraindications: Avoid during pregnancy; consult a physician for drug interactions.

---

7. Product Specifications

Table 1: Quality Compliance of Liquorice Glabridin

Physical Properties:

• Appearance: Fine white to pale yellow powder.

• Solubility: Soluble in ethanol, propylene glycol; insoluble in water.

---

8. Production Workflow

1. Raw Material Cleaning: Ultrasonic removal of soil and impurities.

2. Supercritical Extraction: CO₂-based isolation at 40°C/150 bar.

3. Chromatographic Purification: AB-8 macroporous resin columns.

4. Lyophilization: Freeze-drying to preserve bioactivity.

5. Quality Certification: Third-party validation (SGS, Eurofins).

---

9. Application Scenarios

• Cosmetics: Brightening serums, anti-acne creams.

• Pharma: Anti-inflammatory tablets, diabetic care formulations.

• Nutraceuticals: Antioxidant supplements, metabolic health boosters.

---

10. Quality Control  

Shaanxi Zhonghong adheres to ISO 9001:2015 and cGMP standards, ensuring unmatched product consistency. Our 4-tier QC system includes:

1. Raw Material Screening: Pesticide/heavy metal analysis via GC-MS and ICP-MS.

2. In-Process Checks: Real-time HPLC monitoring of Glabridin purity.

3. Stability Testing: Accelerated aging studies (40°C/75% RH for 6 months).

4. Final Verification: Microbial limits validated per USP and EP guidelines.
   Advanced NMR spectroscopy (Bruker 600 MHz) confirms molecular integrity, while FTIR guarantees batch-to-batch reproducibility.

---

11. Packaging & Logistics

• Primary Packaging: Double-layer aluminum foil bags with oxygen scavengers.

• Bulk Options: 25 kg fiber drums (MOQ: 1 kg).

• Shipping: DDP/DAP via air/sea; cold chain logistics for temperature-sensitive batches.

---

12. Customer Support

• Technical Assistance: Formulation optimization and regulatory guidance.

• Samples: Free R&D samples for efficacy validation.

• Customization: Purity grades (90–99%), particle size adjustments.

---

13. FAQs

Q: Is Liquorice Glabridin vegan-friendly?
A: Yes, 100% plant-derived and cruelty-free.

Q: What’s the lead time for bulk orders?
A: 15–20 days post-quality clearance.

---

14. Conclusion

Liquorice Glabridin by Shaanxi Zhonghong combines scientific rigor and ecological responsibility, offering a premium ingredient for next-gen health innovations.

---

15. References

1. European Pharmacopoeia 11.0 (2023). *Monograph 04/2023: Glycyrrhiza glabra*.

2. Cosmetic Ingredient Review (2024). Safety Assessment of Glabridin.

3. Zhang et al. (2022). Antioxidants, 11(3), 567–582.