Glycine Alpha-Ketoglutarate (GAK) Powder
Bulk Supply | High-Purity Ingredient | GMP-Certified Manufacturer
Glycine Alpha-Ketoglutarate (GAK) is a high-purity amino acid–organic acid complex widely used as a functional ingredient in sports nutrition, dietary supplements, and functional food formulations. AIHerba® supplies bulk Glycine Alpha-Ketoglutarate powder manufactured under GMP-compliant production systems, with full documentation including COA, MSDS, and specification sheets.
As a professional raw material supplier, we focus on consistent batch quality, traceable raw materials, and internationally recognized testing standards, helping global buyers meet formulation, regulatory, and procurement requirements. Our GAK is available in custom particle size, packaging, and OEM/ODM solutions, suitable for long-term contract manufacturing and private-label projects.
AIHerba® supports B2B buyers, distributors, and brand owners seeking a reliable Glycine Alpha-Ketoglutarate supplier for export-oriented markets including North America, Europe, and Asia-Pacific.
1. What Is Glycine Alpha-Ketoglutarate?
Glycine Alpha-Ketoglutarate (GAK) is a stable molecular complex formed from the amino acid glycine and alpha-ketoglutarate, a naturally occurring intermediate in cellular metabolic pathways. In industrial applications, GAK is valued for its high bioavailability, formulation compatibility, and stability, making it suitable for powders, capsules, tablets, and functional blends.
From a formulation perspective, GAK serves as a nutritional support ingredient rather than a pharmaceutical substance, and is commonly used where amino acid supplementation and metabolic intermediates are required.
2. Product Overview
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Product Name: Glycine Alpha-Ketoglutarate
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Synonym: GAK
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Grade: Food / Nutraceutical Raw Material
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Form: Fine powder
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Solubility: Water-soluble
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Manufacturing Standard: GMP, ISO Quality Management
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Documentation: COA, MSDS, TDS available
This product is supplied exclusively as a raw ingredient for further formulation, not as a finished consumer product.
3. Product Source & Raw Material Traceability
AIHerba® sources pharmaceutical-grade glycine and alpha-ketoglutarate intermediates from qualified upstream suppliers with documented quality systems. Each incoming raw material undergoes:
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Identity verification
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Purity and impurity screening
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Heavy metal and microbiological testing
Full batch traceability is maintained from raw material intake through finished product release.
4. Mechanism of Use & Functional Characteristics
(Non-Therapeutic, Scientific Description)
From a biochemical perspective, GAK combines:
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Glycine, a conditionally essential amino acid used in protein synthesis
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Alpha-ketoglutarate, an intermediate involved in cellular nitrogen and carbon metabolism
In formulated products, GAK is used to:
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Support nutritional amino acid supplementation
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Serve as a functional component in sports and performance nutrition
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Enhance ingredient compatibility in complex formulas
No disease prevention or treatment claims are made or implied.
5. Health-Related Use Context (Regulatory-Safe)
GAK is commonly positioned in general nutrition and performance-support formulations. Any health-related statements must comply with local food and supplement regulations and are the responsibility of the finished-product brand owner.
AIHerba® supplies raw materials only and does not provide medical claims.
6. Usage Guidelines (For Formulators)
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Application Forms: Capsules, tablets, sachets, powder blends
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Typical Inclusion Level: Determined by formulation design and local regulations
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Compatibility: Suitable for amino acid blends, protein systems, and functional nutrition matrices
Final dosage and labeling must be validated by the customer’s regulatory and R&D teams.
7. Traditional & Industry Usage Background
Alpha-ketoglutarate salts and amino acid complexes have been studied and utilized for decades within nutritional science and industrial food formulation. Modern applications emphasize purity, stability, and reproducibility rather than traditional medicinal use.
8. Recommended Formulation Strategy (Professional Reference)
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Combine with complementary amino acids for balanced nutritional profiles
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Optimize particle size for capsule filling or instant beverage applications
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Conduct stability testing under target storage conditions
AIHerba® provides technical support for formulation optimization upon request.
9. Safety Notes & Compliance Considerations
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Intended for industrial and commercial formulation use only
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Not intended as a drug or medical treatment
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Customers must ensure regulatory compliance in target markets
10. Product Specification & COA (Example)
10.1 Basic Specifications
| Item | Specification |
|---|---|
| Appearance | White to off-white powder |
| Assay | ≥ 98.0% |
| Loss on Drying | ≤ 1.0% |
| pH (10% solution) | 5.5 – 7.0 |
10.2 Pesticide Residues
| Parameter | Limit | Method |
|---|---|---|
| Organophosphates | Complies | GC-MS |
| Organochlorines | Complies | GC-MS |
| Pyrethroids | Complies | GC-MS |
10.3 Heavy Metals
| Item | Limit | Method |
|---|---|---|
| Lead (Pb) | ≤ 1.0 ppm | ICP-MS |
| Arsenic (As) | ≤ 1.0 ppm | ICP-MS |
| Cadmium (Cd) | ≤ 0.5 ppm | ICP-MS |
| Mercury (Hg) | ≤ 0.1 ppm | ICP-MS |
10.4 Microbiological Limits
| Item | Limit | Method |
|---|---|---|
| Total Plate Count | ≤ 1,000 CFU/g | USP <61> |
| Yeast & Mold | ≤ 100 CFU/g | USP <61> |
| E. coli | Negative | USP <62> |
| Salmonella | Negative | USP <62> |
11. Manufacturing Process & Production Flow
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Raw material qualification
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Precision compounding
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Controlled synthesis reaction
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Purification & filtration
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Drying and milling
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Final blending
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In-house QC testing
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Packaging under GMP conditions
Each batch is released only after quality assurance approval.
12. Storage, Shelf Life & Packaging
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Storage: Cool, dry, sealed environment
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Shelf Life: 24 months
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Standard Packaging: 25 kg fiber drum (food-grade liner)
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Custom Packaging: Available upon request
13. Samples, MOQ & Logistics
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Sample Policy: Free lab sample available (shipping cost may apply)
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MOQ: 25 kg
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Lead Time: 3–7 working days
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Shipping: Air, sea, courier (DDP / CIF / FOB options)
14. Scientific Research & Data Overview
Research on alpha-ketoglutarate and glycine has been published in peer-reviewed journals focusing on nutritional metabolism and biochemical pathways.
Reference Sources:
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PubMed – Alpha-Ketoglutarate Metabolism
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NIH – Amino Acid Biochemistry
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FDA – Dietary Ingredient Regulatory Framework
(Links provided for reference only; no claims implied.)
15. Applicable Industries & Use Scenarios
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Dietary Supplements
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Sports Nutrition
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Functional Foods & Beverages
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R&D Laboratories
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Contract Manufacturing
16. Why Choose AIHerba®?
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28+ years manufacturing experience
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GMP & ISO quality systems
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In-house laboratory testing
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Stable global supply chain
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OEM / ODM customization support
Produced by AIHerba, a professional exporter serving international B2B clients.
17. Frequently Asked Questions (FAQ)
1. Is Glycine Alpha-Ketoglutarate suitable for food formulations?
Yes. AIHerba® Glycine Alpha-Ketoglutarate is produced under GMP and ISO-certified conditions, making it suitable as an ingredient for dietary supplements, functional foods, beverages, and sports nutrition formulations. It is a nutritional raw material, and customers should comply with local regulatory requirements for finished product labeling.
2. Can you provide full COA and MSDS before ordering?
Absolutely. For every batch, we provide a Certificate of Analysis (COA), Material Safety Data Sheet (MSDS), and Technical Data Sheet (TDS). These documents include purity, heavy metals, pesticide residues, and microbiological testing results, ensuring full transparency and regulatory compliance.
3. Do you support OEM or private-label projects?
Yes. AIHerba® offers OEM and ODM services, including custom formulations, packaging solutions, and labeling options. We support global B2B clients in creating private-label products, functional blends, and nutraceutical ingredient solutions with technical guidance from our R&D team.
4. What is the typical lead time for bulk orders?
Standard lead time for bulk orders is 3–7 working days for ready-to-ship stock. For custom specifications or OEM projects, lead time depends on formulation, packaging, and order quantity. We provide detailed production and delivery schedules for each order.
5. Is the product compliant with international standards?
Yes. AIHerba® GAK is produced according to GMP, ISO, and HACCP standards, and undergoes rigorous quality testing for heavy metals, pesticides, and microbiological contamination. It is suitable for use in North American, European, and Asian markets according to local regulatory requirements.
6. Can particle size be customized?
Yes. Depending on the application (capsules, tablets, powders, instant beverages), we can customize particle size distribution to meet formulation requirements. Technical guidance and sampling are provided to ensure optimal solubility and compatibility.
18. Contact & Verification
AIHerba® | China Natural Plant Extracts Supplier & OEM Factory
AIHerba (Shaanxi Zhonghong Investment Technology Co., Ltd.)
📧 sales@aiherba.com
📧 info@aiherba.com
📧 liaodaohai@gmail.com
🌐 www.aiherba.com
Bulk Supply & Technical Support
Get direct factory quotes, COA, and MSDS within 12 hours. We support bulk supply and custom specifications.





