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Pharmaceutical-Grade Glutathione Manufacturer | Factory with 28+ Years Experience

Glutathione Benefits, Applications, and Supplier Guide – AIHerba® Natural Extracts

  1. English Name: Glutathione

  2. Specification: ≥ 98% (HPLC); available in water-soluble and oil-soluble grades.

  3. Appearance: Yellowish-white crystalline powder with a mild natural aroma.

  4. CAS No.: 70-18-8

  5. Lead Time: 3–7 working days depending on order size.

  6. Package: 25 kg/drum; 27 drums per pallet; OEM/ODM packaging available.

  7. Main Market: Europe, North America, Asia; widely supplied to nutraceutical, cosmetic, and functional food sectors.

  8. Applications / Key Benefits: Supports antioxidant defense, detoxification, skin brightening, and overall wellness; commonly used in dietary, cosmetic, and wellness formulations.

  9. Industry Applications:
    a) Dietary Supplements – Antioxidant and detox blends.
    b) Functional Foods & Beverages – Fortified wellness drinks and powders.
    c) Cosmetics & Personal Care – Skin-brightening creams, serums, and lotions.
    d) Pharmaceuticals (Region-Specific) – Detox and antioxidant-support preparations.
    e) Herbal Health Products – Wellness, antioxidant, and skin-support formulations.

Bulk High-Purity Glutathione Powder – OEM & Wholesale Supply for Cosmetics & Supplements

1. Glutathione Powder (Reduced L-Glutathione)

Bulk Ingredient Supplier | GMP Factory | OEM & ODM Available

Glutathione is a naturally occurring tripeptide composed of glutamic acid, cysteine, and glycine, widely used as a high-value antioxidant ingredient in dietary supplements, functional foods, cosmetics, and pharmaceutical research applications. As a trusted bulk glutathione supplier, AIHerba provides high-purity reduced L-glutathione powder manufactured under GMP and ISO quality systems, ensuring batch-to-batch consistency, traceable raw materials, and verified analytical data.

Our glutathione powder is produced using controlled fermentation and advanced purification technologies, delivering excellent stability, solubility, and formulation compatibility. Designed specifically for B2B buyers, brand owners, and formulation engineers, AIHerba offers wholesale supply, customized specifications, OEM/ODM services, and full COA documentation. Whether used in capsules, tablets, beverages, or cosmetic formulations, our glutathione meets international regulatory expectations and professional manufacturing standards.


2. What Is Glutathione?

Glutathione (GSH) is an endogenous antioxidant found in almost all living cells. It plays a central role in cellular redox balance, detoxification pathways, and maintenance of oxidative stability. In industrial applications, reduced L-glutathione is preferred due to its bioactive form and higher functional value.


3. Product Type & Source

  • Product Name: Reduced L-Glutathione Powder

  • CAS No.: 70-18-8

  • Molecular Formula: C₁₀H₁₇N₃O₆S

  • Molecular Weight: 307.32

  • Source: Microbial fermentation (non-animal origin)

  • Appearance: White to off-white crystalline powder

  • Solubility: Freely soluble in water


4. Mechanism of Action & Functional Benefits (Non-Therapeutic)

Glutathione functions primarily as a cellular antioxidant system component:

  1. Participates in free radical neutralization

  2. Supports redox homeostasis

  3. Contributes to detoxification enzyme pathways

  4. Maintains protein and lipid stability

  5. Acts as a cofactor in enzymatic reactions

These functions are based on biochemical and nutritional science and are not intended to diagnose, treat, or cure diseases.


5. Health & Wellness Applications (Structure-Function Level)

  • Antioxidant support formulations

  • Nutritional supplements for general wellness

  • Functional food and beverage systems

  • Cosmetic formulations targeting oxidative stability


6. Usage Guide (Industrial & Formulation Reference)

  • Dietary Supplements: Capsules, tablets, sachets

  • Functional Beverages: Powder blends, liquid shots

  • Cosmetics: Serums, emulsions, creams

  • Pharma R&D: Excipient or active research use


7. Traditional & Scientific Background

Glutathione has been extensively studied in nutritional biochemistry and cellular metabolism research for over five decades and is recognized as a core endogenous antioxidant molecule in human physiology.


8. Recommended Dosage (Formulation Reference Only)

  • Typical formulation range: 50–500 mg per serving

  • Dosage depends on application, formulation type, and regional regulations

  • Final dosage should be determined by qualified professionals


9. Best Formulation Guidance

  • Compatible with vitamin C, alpha-lipoic acid, selenium

  • Avoid prolonged exposure to high heat and strong oxidizers

  • Recommended pH range: 5.0–7.0


10. Safety & Handling Notes

  • For industrial use only

  • Not intended as a finished consumer product

  • Follow local regulatory compliance for end-use applications


11. Product Specifications & COA (Example)

11.1 Active Ingredient Specification

Item Specification Method
Assay (GSH) ≥ 98.0% HPLC
Loss on Drying ≤ 0.5% USP
Optical Rotation +15.5° to +17.5° USP

11.2 Pesticide Residue Testing

Parameter Limit Method
Organophosphates Conforms GC-MS
Organochlorines Conforms GC-MS
Pyrethroids Conforms GC-MS

11.3 Heavy Metals

Item Limit Method
Lead (Pb) ≤ 1.0 ppm ICP-MS
Arsenic (As) ≤ 1.0 ppm ICP-MS
Cadmium (Cd) ≤ 0.5 ppm ICP-MS
Mercury (Hg) ≤ 0.1 ppm ICP-MS

11.4 Microbiological Standards

Item Limit Method
Total Plate Count ≤ 1,000 CFU/g USP
Yeast & Mold ≤ 100 CFU/g USP
E. coli Negative USP
Salmonella Negative USP

12. Manufacturing Process

  1. Controlled microbial fermentation

  2. Enzymatic synthesis & purification

  3. Filtration and concentration

  4. Crystallization

  5. Drying and milling

  6. Final QC testing & packaging


13. Storage, Shelf Life & Packaging

  • Storage: Cool, dry, sealed, protected from light

  • Shelf Life: 24 months

  • Packaging: 1 kg aluminum foil bag / 25 kg fiber drum

  • Custom packaging: Available


14. Sample Policy, Shipping & MOQ

  • Samples: Available upon request

  • MOQ: 1 kg (stock products)

  • Shipping: Air / Sea / Express

  • Lead Time: 3–7 working days


15. Clinical Data & Research Overview

  • Extensive studies on antioxidant function

  • Recognized in nutritional science literature

  • Widely referenced in cellular metabolism research


16. Applicable Industries & Use Scenarios

  • Dietary Supplements

  • Functional Foods & Beverages

  • Cosmetics & Personal Care

  • Pharmaceutical R&D


17. Why Choose AIHerba®

  • Experience: 28+ years manufacturing expertise

  • Authority: GMP, ISO certified factory

  • Trust: Full traceability, third-party testing

  • Support: OEM/ODM & formulation assistance


18. Frequently Asked Questions (FAQ)

  1. 1. Is your glutathione synthetic or fermentation-derived?

    Our glutathione is fermentation-derived and produced using a controlled microbial fermentation process, followed by advanced purification and crystallization.
    This method ensures non-animal origin, high purity, and consistent molecular structure, making it suitable for dietary supplement, cosmetic, and functional food applications.
    No animal tissue extraction is involved.


    2. Can you provide a COA for each batch?

    Yes. A complete Certificate of Analysis (COA is provided for every production batch).

    Each COA typically includes:

    • Assay (HPLC)

    • Identification & purity

    • Heavy metals (ICP-MS)

    • Microbiological limits

    • Loss on drying & physical properties

    Batch numbers are fully traceable to raw material sourcing, production records, and QC testing under our GMP quality system.


    3. Is the product suitable for cosmetic use?

    Yes. Our glutathione is suitable for cosmetic and personal care formulations, including serums, creams, emulsions, and masks.

    Key cosmetic-relevant features:

    • High purity and low impurity profile

    • Water-soluble and formulation-friendly

    • Manufactured under GMP & ISO conditions

    • Supported by cosmetic-grade analytical data

    Final usage levels and claims should comply with local cosmetic regulations in the destination market.


    4. What is the difference between reduced and oxidized glutathione?

    Type Description Industrial Preference
    Reduced Glutathione (GSH) Bioactive form with free thiol group (-SH) ✔ Widely used
    Oxidized Glutathione (GSSG) Dimer form formed after oxidation Limited use

    Reduced L-glutathione (GSH) is the preferred form for supplements and cosmetics due to its higher functional relevance and stability in formulations.


    5. Do you support private label or OEM formulations?

    Yes. We provide OEM & ODM services for B2B partners worldwide.

    Our services include:

    • Custom specifications & concentrations

    • Private label packaging (bulk or retail)

    • Formulation support for supplements, cosmetics, and functional foods

    • Regulatory and documentation assistance

    We work closely with brand owners, contract manufacturers, and distributors.


    6. What regulatory documents are available for export?

    We can provide a comprehensive export documentation package, including:

    • Certificate of Analysis (COA)

    • MSDS / SDS

    • GMP & ISO certificates

    • Product Specification Sheet

    • Allergen Statement

    • Non-GMO Statement

    • Country of Origin

    • Stability & shelf-life data (upon request)

    Additional documents can be prepared based on destination country regulations and customer requirements.


19. References & Regulatory Sources

  1. PubMed – Glutathione metabolism research
    https://pubmed.ncbi.nlm.nih.gov

  2. NIH – Antioxidant systems overview
    https://www.nih.gov

  3. FDA – Dietary ingredient guidance
    https://www.fda.gov


20. Manufacturer Information

AIHerba® | China Natural Plant Extracts Supplier & OEM Factory
AIHerba (Shaanxi Zhonghong Investment Technology Co., Ltd.)
📧 sales@aiherba.com | info@aiherba.com | liaodaohai@gmail.com
🌐 https://www.aiherba.com

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