Bulk Reduced L-Glutathione Powder Wholesale | GMP Manufacturer

1. Reduced L-Glutathione (GSH) Powder 98% | GMP Manufacturer, Bulk & Wholesale Supplier

Looking for a reliable bulk supplier of Reduced L-Glutathione (GSH) with consistent purity, documentation, and traceability? AIHerba supplies L-Glutathione powder (CAS 70-18-8) to B2B procurement teams, factories, brands, and OEM/ODM partners who need stable specs, controlled impurities, and export-ready files. Every batch is released under defined quality control and can be supported with COA and MSDS/SDS, specification mapping, and lot tracking for audit readiness. We support industrial buyers with practical procurement details—MOQ, lead time, packaging options, and compliance statements—so you can qualify the ingredient faster and reduce supply risk.
CTA: Request specifications + COA + pricing from our sales team (bulk / wholesale / OEM).

Quick Summary

• Ingredient name: Reduced L-Glutathione (L-Glutathione, GSH)

• CAS No.: 70-18-8

• Main applications: Dietary supplement formulations, cosmetic formulations, industrial antioxidant functional use

• Typical purity: ≥ 98.0% (HPLC) (custom specs available)

• Suitable industries: Supplements, cosmetics/personal care, contract manufacturing, ingredient distribution

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2. What Is Reduced L-Glutathione (GSH)?

Reduced L-Glutathione (GSH) is a naturally occurring tripeptide (glutamate–cysteine–glycine) widely used as an ingredient where antioxidant-related functional properties and formulation compatibility are relevant. Basic identity references (CAS/formula/structure) are commonly listed in PubChem.

Benefits (Regulatory-Safe, Non-Medical)

• Functional property: commonly selected for antioxidant-related positioning in ingredient systems (no disease claims).

• Formulation role: may support oxidative stability in certain blends where redox-sensitive ingredients are present (validation required in your matrix).

• Quality-driven buying: buyers often evaluate GSH by purity profile (HPLC), moisture, heavy metals, and microbiological limits.

Applications

• Supplements: capsules, tablets, powders, stick packs (as a functional ingredient).

• Cosmetics: skincare formulas where ingredient purity/odor/color control is critical.

• Industrial application: ingredient premixes or specialty blends requiring defined specs and traceability.

Dosage / Specification (B2B Page Guidance)

• B2B note: finished-product dosage depends on your local regulations, product positioning, and formulation design. We provide ingredient specification, typical use-level ranges on request, and compatibility notes for OEM/ODM projects.

• Purchasing spec focus: assay (HPLC), impurities, heavy metals, micro, residual solvents (if required), and stability handling guidance.

Safety

This page describes an ingredient for industrial use. It does not claim to diagnose, treat, cure, or prevent disease. For finished products, brands should follow applicable labeling rules and substantiation requirements (e.g., FDA structure/function claim framework in the U.S.).

Supplier / Manufacturer (Factory Identity)

AIHerba supports manufacturer-to-business procurement with documentation, lot traceability, and quality systems aligned to GMP expectations (dietary supplement cGMP is commonly referenced in 21 CFR Part 111 for U.S. market operations).

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3. Detailed Technical Specifications (Table)

Note: Limits can be customized to your target market and internal purchasing specification (USP/EP/ISO mapping available upon request). EP monograph references exist for Glutathione.

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4. Product Source & Raw Material Origin

Reduced L-Glutathione for industrial supply is typically produced through controlled chemical or bioprocess routes followed by purification, drying, and milling. For procurement, what matters most is raw material qualification, process controls, and traceability—not marketing narratives.

What we provide for origin transparency (B2B-ready):

• Country of origin statement (on request)

• Lot-level traceability documentation (raw → process → finished goods)

• Supplier qualification and incoming QC records (audit-based, shareable under NDA)

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5. Mechanism of Action & Functional Properties (Non-Medical)

In ingredient science terms, GSH participates in redox balance and is widely referenced as an antioxidant-related molecule in biochemical contexts. PubChem summarizes glutathione’s role as an antioxidant/free radical scavenger in a general biochemical description.

Functional properties relevant to industrial application:

• Redox-active thiol group (–SH) influences oxidation-reduction behavior

• Can be oxidation-sensitive in aqueous environments; handling and packaging are key for quality preservation (see storage section).

• Stability in solution can vary by pH, temperature, oxygen exposure, and chelation environment (formulators should validate).

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6. Application-Relevant Benefits (Regulatory-Safe)

For B2B buyers, “benefit” means procurement performance and formulation usability:

• Batch consistency: stable HPLC assay and impurity profile reduce re-work in incoming QC.

• Documentation speed: COA/MSDS + spec mapping shorten supplier qualification cycles.

• Export practicality: packaging, labeling, and shipping documents prepared for international trade.

• Formulation utility: commonly used where antioxidant functional properties are desired (no therapeutic claims).

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7. Usage Guidelines & Formulation Recommendations

Supplement formulations (OEM/ODM):

• Recommend confirming compatibility with excipients, humidity control, and target shelf life.

• For tablet/capsule: focus on moisture, compressibility aids, and oxygen exposure management.

• For powders/stick packs: use moisture-barrier packaging and consider oxygen scavenging where appropriate.

Cosmetic formulations:

• Validate solubility and stability in your pH range; confirm color/odor acceptance in finished formula.

• Request tighter limits for trace metals if your formula is oxidation-sensitive.

Internal link suggestions (anchor text examples):

• “OEM/ODM formulation services” → link to your OEM/ODM page

• “Quality management & certifications” → link to your QA/QC page

• “Request COA/MSDS” → link to your COA request / contact page

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8. Traditional & Modern Industrial Applications

• Modern: functional ingredient in supplements; cosmetic ingredient in skincare systems; component in industrial premixes.

• Traditional/industry practice: positioned historically as an antioxidant-related compound in ingredient literature (avoid medical positioning; focus on functional property use).

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9. COA & Quality Control Specifications (Tables)

Below tables are procurement-friendly templates for COA review. Final acceptance criteria should match your local regulations and your internal specifications. Methods can be aligned to pharmacopeial standards upon request (USP/EP).

9.1 Pesticide Residues (Screening Template)

(GSH is commonly synthetic/bioprocess-derived; many buyers still require a pesticide panel for compliance harmonization in multi-ingredient supply chains.)

9.2 Heavy Metals

9.3 Microbiological Limits

Quality Control (what buyers can verify):

• Lot number on packaging + COA matching

• Retain sample policy (on request)

• Audit support under NDA for key accounts

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10. Manufacturing Process & Production Flow

A procurement-grade view of the manufacturing process emphasizes control points—not vague claims:

1. Incoming raw material qualification (identity, purity, supplier qualification)

2. Controlled production under documented parameters

3. Purification to meet assay and impurity profile

4. Drying & milling to defined moisture and particle size targets

5. In-process checks (CQA monitoring)

6. Final QC release (HPLC assay + safety parameters)

7. Packaging in moisture/oxygen barrier materials

8. Batch traceability records archived for verification

For buyers referencing API-style GMP frameworks, ICH Q7 is a commonly cited GMP guideline for active pharmaceutical ingredient manufacturing quality systems.

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11. Storage, Shelf Life & Packaging

Storage: cool, dry, protected from light; avoid prolonged exposure to air and humidity.
Shelf life (typical): 24 months (subject to packaging, storage, and batch confirmation).
Packaging options (bulk/wholesale):

• 1 kg aluminum foil bag (double-bagging available)

• 5 kg / 10 kg foil bag

• 25 kg fiber drum with inner double PE liner

• Custom labeling for OEM/ODM projects

Why packaging matters: Reduced glutathione can oxidize in solution and is sensitive to environment; controlling oxygen and moisture improves stability in the supply chain.

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12. MOQ, Sample Policy & Global Shipping

MOQ: typically 1 kg for sampling/qualification; bulk MOQs available for contract pricing.
Sample policy:

• COA-backed sample for lab verification

• Support for buyer QC (HPLC comparison, identity checks)

Lead Time:

• Standard lead time depends on inventory and production schedule; fast dispatch is available for stocked batches.

Global shipping:

• Air / sea / courier, with export documents: COA, MSDS/SDS, packing list, invoice, and country-of-origin statement (as applicable).

• Cold-chain is usually not required for the powder when properly packaged, but we can follow buyer logistics SOP.

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13. Clinical Data & Scientific Research (Cited Only, No Medical Conclusions)

This section is provided for scientific context and procurement substantiation; it does not imply medical efficacy or therapeutic claims.

• A long-term randomized, double-blind, placebo-controlled trial in healthy adults reported changes in glutathione levels with oral supplementation at 250 mg/day and 1,000 mg/day over 6 months. (Use for context only; brands must ensure compliant claims.)

• Additional published discussions and trials explore supplementation and biomarkers in specific populations; these do not automatically translate to finished-product claims and should not be used as disease claims.

• ClinicalTrials.gov contains records related to glutathione supplementation research (registry entries are not proof of outcomes).

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14. Applicable Industries

• Dietary supplement brands & contract manufacturers (OEM/ODM)

• Cosmetics/personal care brands and ingredient labs

• Importers, distributors, and wholesale ingredient traders

• Factories producing functional premixes and white-label products

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15. Industry Application Scenarios (Real B2B Use Cases)

1. OEM capsule line (Brand → Contract Manufacturer):
   A brand needs GSH with consistent assay and low moisture to reduce capsule clumping and improve fill-weight control. Procurement requires COA lot matching, micro limits, and stable lead time for monthly production cycles.

2. Skincare formulation sourcing (Cosmetic lab → Bulk supplier):
   A formulator requests tighter trace-metal limits and odor/color control to avoid instability in a water-based serum. Supplier is evaluated on QC responsiveness, documentation completeness (SDS/COA), and packaging barrier performance.

3. Distributor qualification (Ingredient trader → Multi-country customers):
   A distributor qualifies GSH for multiple markets and needs standardized documentation packs plus traceability to handle audits. Supplier must provide consistent specification mapping, batch records, and predictable wholesale pricing tiers.

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16. Supplier Comparison & Procurement Guide

When comparing a Glutathione manufacturer / supplier, prioritize verifiable controls:

A. Factory capability (Experience)

• Documented production flow, QC release criteria, and packaging SOP

• Batch traceability and retain sample policy

B. Technical fit (Expertise)

• HPLC assay method and impurity discussion

• Micro and heavy metal limits aligned to your market requirements

• Stability and handling guidance (humidity/oxygen control)

C. Compliance readiness (Authoritativeness)

• GMP/ISO scope and audit support

• COA/MSDS completeness

• Ability to reference and map to USP/EP expectations where relevant

D. Trust signals (Trustworthiness)

• Lot-to-COA matching, consistent labeling

• Responsive corrective action when deviations occur

• Clear contact channels and accountable commercial terms (MOQ, lead time, replacement policy)

Pricing note (B2B reality):
“Best pricing” is usually driven by purity level, impurity limits, documentation depth, and order volume. Ask for a quote with your target spec, annual volume, packaging, and destination port to get a procurement-meaningful price.

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17. FAQ for B2B Buyers (6)

1. Do you provide COA and MSDS/SDS?
   Yes. We can provide COA for each batch and MSDS/SDS for shipping and handling, plus specification sheets and compliance statements.

2. What is your MOQ for bulk orders and for samples?
   Sample MOQ is typically 1 kg for qualification; wholesale/bulk MOQ depends on pricing tier and packaging.

3. What is the typical purity/assay?
   Typical assay is ≥ 98.0% (HPLC); tighter or customized impurity limits can be offered for specific applications.

4. What is the lead time?
   Lead time depends on stock and production scheduling; repeat orders can be planned with forecast support to stabilize supply.

5. Can you support USP/EP specification mapping?
   We can support spec mapping and method discussions aligned to your regulatory and QC expectations; EP references exist for glutathione monographs.

6. How do you ensure batch traceability?
   Each shipment carries a lot number linked to incoming QC, production records, final QC release, and COA issuance.

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19. References & Regulatory Sources

Identity / Chemical reference (NIH):
– PubChem Compound (Glutathione, CID 124886): https://pubchem.ncbi.nlm.nih.gov/compound/124886
– PubChem data (REST view used for identity context): https://pubchem.ncbi.nlm.nih.gov/rest/pug_view/data/compound/124886/XML/?response_type=display

U.S. regulatory / compliance framing:
– 21 CFR Part 111 (Dietary Supplement cGMP, eCFR): https://www.ecfr.gov/current/title-21/chapter-I/subchapter-B/part-111
– FDA overview page: Current Good Manufacturing Practices (CGMPs) for Dietary Supplements: https://www.fda.gov/food/current-good-manufacturing-practices-cgmps-food-and-dietary-supplements/current-good-manufacturing-practices-cgmps-dietary-supplements
– FDA: Structure/Function Claims (DSHEA context): https://www.fda.gov/food/nutrition-food-labeling-and-critical-foods/structurefunction-claims

Pharmacopoeia / standards reference:
– EP monograph PDF copy (Glutathione): https://www.uspbpep.com/ep60/glutathione%201670e.pdf
– ICH Q7 (API GMP guidance, EMA page): https://www.ema.europa.eu/en/ich-q7-good-manufacturing-practice-active-pharmaceutical-ingredients-scientific-guideline
– FDA Q7 guidance PDF: https://www.fda.gov/media/71518/download

Scientific literature / research databases:
– Europe PMC record for oral GSH RCT context (not a claim): https://europepmc.org/article/MED/24791752
– ClinicalTrials.gov record (registry, not outcome proof): https://clinicaltrials.gov/study/NCT01044277

ISO standard overview (food safety management):
– ISO 22000 overview (ISO): https://www.iso.org/iso-22000-food-safety-management.html

• “Request COA, specifications, and bulk pricing (reply within 24h).”

• “Send your target spec + annual volume for a wholesale quotation.”

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Manufacturer & Quality Assurance

Manufactured by AIHerba® (Shaanxi Zhonghong Investment Technology Co., Ltd.),
a GMP-certified manufacturer specializing in high-purity botanical extracts
for dietary supplements, cosmetics, and pharmaceutical applications.
✔ GMP-certified production facility
✔ Full COA & technical specifications available
✔ Batch traceability & strict quality control
✔ Bulk supply & OEM/ODM services for global B2B buyers
📧 sales@aiherba.com
| info@aiherba.com
| liaodaohai@gmail.com
🌐 www.aiherba.com

If you are looking for a bulk supplier / OEM manufacturer of Reduced L-Glutathione (GSH), contact us for specifications, COA, and pricing.