Glutamic Acid

Glutamic Acid Raw Material – Customized Herbal Extracts & Factory Direct Supply

1. English Name: Glutamic Acid; 2-Aminopentanedioic acid

2. Specification

• • Purity: Glutamic Acid ≥ 99.0% (HPLC)

• • Optical Purity: L – Glutamic Acid ≥ 99.0% (for chiral products), D – Glutamic Acid available for specific applications

• • Solubility: Sparingly soluble in cold water (0.86 g/100 mL at 25°C), soluble in hot water and strong acids/alkalis; water – soluble salts (e.g., monosodium glutamate) have higher solubility

• • Particle Size: Standard powder ≤ 150 μm; spray – dried powder ≤ 50 μm for better flowability

3. Appearance

• • Powder: White to off – white crystalline powder, odorless, slightly acidic taste

4. CAS NO.：56 – 86 – 0 (L – Glutamic Acid); 6893 – 11 – 8 (D – Glutamic Acid)

5. Lead time: 3 – 5 Working Days

6. Package

• • 25 kg/drum (polyethylene bag inside cardboard drum), 1000 kg/super sack for bulk orders

7. Main Market: Global market, with significant demand in Asia (China, Japan), North America, and Europe

8. Application Scenarios

• Molecular Formula: C₅H₉NO₄

• Ionization Behavior: Amphoteric compound with three ionizable groups (α – amino, α – carboxyl, and γ – carboxyl), pKa values: 2.19 (α – COOH), 4.25 (γ – COOH), 9.67 (α – NH₂)

• Key Features

• • Protein Building Block: One of the 20 standard amino acids, essential for protein synthesis in living organisms.

• • Neurotransmitter Precursor: In the human body, L – Glutamic Acid is a precursor to the neurotransmitter glutamate, crucial for nerve signal transmission.

• • Flavor Enhancer: Its sodium salt, monosodium glutamate (MSG), provides umami taste, widely used in the food industry.

• • Metabolic Intermediate: Involved in the Krebs cycle and nitrogen metabolism, playing a key role in energy production and amino acid balance.

• Flavor Enhancement:

• • As the raw material for monosodium glutamate (MSG), added to soups, sauces, snacks, and instant noodles at 0.1 – 1% concentration to enhance umami flavor.

• • Used in meat – based products, seasonings, and vegetarian dishes to improve taste.

• Nutritional Fortification:

• • Added to infant formulas, sports drinks, and nutritional supplements to increase protein content and support amino acid balance.

• • In baked goods, it can improve dough elasticity and shelf – life.

• Nutraceuticals and Supplements:

• • Capsules or tablets containing L – Glutamic Acid (500 – 1000 mg per serving) are sold for brain health support, as it aids in neurotransmitter synthesis and may improve cognitive function.

• • Used in amino acid infusion solutions for patients with nutritional deficiencies or recovering from surgery.

• Drug Synthesis:

• • Serves as an intermediate in the synthesis of various drugs, such as anticonvulsants and antidepressants, due to its role in the nervous system.

• Protein Source:

• • Added to livestock, poultry, and aquaculture feed at 0.5 – 2% to improve the amino acid profile, enhance growth performance, and increase feed efficiency.

• • In pet food, it helps meet the protein requirements of animals, especially during growth and recovery periods.

• Skin Moisturizer:

• • Incorporated into creams, lotions, and serums (0.5 – 2% concentration) to improve skin hydration, as it has water – binding properties.

• • Used in anti – aging products for its potential to stimulate collagen synthesis.

• Hair Care:

• • Added to shampoos and conditioners to strengthen hair fibers and improve hair elasticity.

• Biodegradable Plastics:

• • As a raw material for the synthesis of poly(glutamic acid), which is used to produce biodegradable polymers for packaging materials.

• Water Treatment:

• • Its derivatives can be used as chelating agents to remove heavy metals from water, binding to metal ions and facilitating their removal.

• High – Performance Liquid Chromatography (HPLC):

• • Column: C18 (250 × 4.6 mm, 5 μm), Mobile Phase: 0.1% phosphoric acid – acetonitrile (95:5 v/v), Flow Rate: 1.0 mL/min, Detection Wavelength: 210 nm for quantification.

• Ion – Exchange Chromatography:

• • Used for separating and analyzing different forms of glutamic acid (e.g., L – and D – isomers) based on their ionic properties.

• Amino Acid Analyzer:

• • Specifically designed equipment that uses ion – exchange chromatography and post – column derivatization with ninhydrin to accurately measure the concentration of glutamic acid in complex samples.

• Natural Source: Produced by fermentation of carbohydrates (e.g., molasses, glucose) using microorganisms like Corynebacterium glutamicum.

• Cost – Effective: Large – scale industrial fermentation processes ensure a stable and affordable supply.

• Versatile: Its wide range of applications from food to industrial sectors makes it a valuable commodity in the global market.

• US FDA: GRAS – listed for use as a flavor enhancer and nutrient in food products. Meets cGMP requirements for pharmaceutical – grade products.

• EU Regulation: Approved as a food additive (E620 for glutamic acid and its salts) with specific usage limits in different food categories.

• China NMPA: Permitted for use in food, pharmaceuticals, and animal feed, subject to strict quality control standards.