AIHerba® Fisetin Supplement (98% HPLC) – High-Purity Botanical Extract for Nutraceutical, Anti-Aging & Functional Food Formulations

AIHerba® (Shaanxi Zhonghong Investment Technology Co., Ltd.) is a GMP-certified manufacturer and long-term supplier of high-purity herbal extracts used in nutritional supplements, cosmetics, pharmaceuticals, and functional foods.
Our Fisetin supplement is standardized to 98% purity (HPLC) and produced using advanced water-ethanol extraction and column chromatography to meet global industry standards.

📧 Contact: sales@aiherba.com | info@aiherba.com | liaodaohai@gmail.com
🌐 www.aiherba.com

1. Product Overview

Fisetin is a naturally occurring flavonol found in strawberries, apples, mangoes, and Rhus succedanea. In recent years, it has become one of the most researched plant-based senolytic ingredients, widely used in healthy aging, cognitive support, antioxidant formulations, and cellular vitality products.

AIHerba® Fisetin Supplement is:

• 98% purity (HPLC)

• Non-GMO, solvent-free residue compliant

• Suitable for capsules, tablets, hard candies, gummies, beverages, and powder blends

• Manufactured in a GMP & ISO9001-certified factory

2. Botanical Source & Origin

• Botanical Name: Rhus succedanea

• Plant Part Used: Fruit

• Extraction Method: Water-ethanol extraction + column chromatography

• Country of Origin: China

• Appearance: Bright yellow crystalline powder

• Assay: ≥ 98% (HPLC)

3. Key Health Benefits (Science-Supported)

3.1 Cellular Senolytic Activity

Fisetin has been extensively studied for its ability to help clear senescent cells—cells that drive aging and inflammation.
• Research from Mayo Clinic and NIH-backed studies suggest fisetin may offer strong senolytic activity compared to other flavonoids (PubMed ID: 29791247).

3.2 Antioxidant Protective Effects

Fisetin has demonstrated potent antioxidant properties, helping neutralize free radicals and protect against oxidative stress (PubMed ID: 25961620).

3.3 Cognitive Support

Studies indicate fisetin may support memory formation, neuronal signaling, and synaptic function (PubMed ID: 20633536).

3.4 Metabolic & Inflammatory Balance

Preclinical studies show fisetin may help maintain healthy inflammation responses, blood sugar regulation, and metabolic function (PubMed ID: 19478309).

3.5 Skin & Anti-Aging Benefits

Fisetin helps reduce damage from UV exposure, oxidative stress, and glycation—making it a popular ingredient for anti-aging skincare and nutricosmetics (NIH report on flavonoids and skin health).

4. Applications & Suitable Industries

AIHerba® Fisetin is widely used in:

5. Recommended Dosage & Usage Guide

• Typical Daily Dose: 100–500 mg/day (based on supplement industry norms)

• Senolytic Protocol: 500–1,000 mg/day for 2 consecutive days per month (based on research models; manufacturers should conduct safety assessments before commercial claims)

• Forms: Capsules, tablets, stick packs, drinks, gummies, sachets

• Solubility: Poorly water-soluble—use lipid carriers or cyclodextrin for improved absorption

• Best Stack Partners:

  • Quercetin

  • NMN / NR

  • Resveratrol

  • CoQ10

  • Curcumin

6. Traditional Applications

Although modern fisetin research is recent, its plant source (Rhus succedanea) has been historically used in Asian herbal practices for:

• Clearing heat and toxins

• Supporting liver health

• Anti-inflammatory remedies

• Natural coloring and traditional extracts

7. Product Specifications (Typical COA)

7.1 General Specifications

7.2 Pesticide Residue Testing

7.3 Heavy Metals

7.4 Microbiology

8. Production Process & Manufacturing Flow

AIHerba® uses a controlled, traceable production system:

1. Raw Material Selection – Verified plant origin, pesticide-controlled farms

2. Cleaning & Crushing – Low-temperature mechanical powdering

3. Water-Ethanol Extraction – Removes active flavonols

4. Filtration & Purification – Multi-step membrane and resin purification

5. Column Chromatography – Achieves 98% fisetin purity

6. Concentration & Crystallization

7. Low-Temperature Drying

8. Milling & Standardization

9. Metal Detection & Microbial Testing

10. Final Packaging in GMP Workshops

9. Storage, Shelf Life & Packaging

• Shelf Life: 24 months (cool, dry environment)

• Storage: Store below 25°C, away from moisture and light

• Packaging Options:

  • 1 kg aluminum foil bags

  • 25 kg fiber drums

  • Customized OEM packaging available

• Labeling: Batch number, production date, expiration date, QR traceability

10. MOQ, Samples & Logistics

• MOQ: 1 kg for bulk orders

• Samples: 10–20 g free samples (freight collect)

• Lead Time: 3–7 working days

• Shipping Options: DHL, FedEx, UPS, air cargo, sea freight

• Trade Terms: EXW, FOB, CIF, DDP

• Bulk & Wholesale Orders: Preferential price for ≥25 kg purchases

11. Quality Certifications

GMP, ISO 9001, ISO 22000, HACCP, Halal, Kosher, COA, MSDS, TDS, third-party testing available

12. Why Choose AIHerba® as Your Fisetin Supplier?

1. 28+ years of manufacturing experience in botanical extraction

2. Advanced extraction factory with GMP workshops

3. Transparent testing, COA, and traceable raw materials

4. Bulk supply, stable long-term inventory

5. OEM/ODM formulation support for global brands

6. Responsive technical support with real-time documentation

7. Competitive wholesale solutions and factory price

13. Common Questions (FAQ)

Q1: What purity do you supply?

We supply 98% HPLC fisetin, suitable for high-end senolytic and anti-aging formulas.

Q2: Can I buy a small test batch?

Yes, MOQ is only 1 kg, and samples are available.

Q3: Is fisetin stable in beverages?

It is more stable in dry powders; beverage applications may require encapsulation.

Q4: Do you offer OEM & ODM services?

Yes, we support capsules, tablets, stick packs, gummies, and custom blends.

Q5: What’s your delivery time?

Typically 3–7 working days depending on quantity and documentation required.

14. Scientific References (PubMed / NIH / FDA)

1. Senolytic activity of fisetin – PubMed: https://pubmed.ncbi.nlm.nih.gov/29791247

2. Antioxidant properties – https://pubmed.ncbi.nlm.nih.gov/25961620

3. Neuroprotective/cognitive effects – https://pubmed.ncbi.nlm.nih.gov/20633536

4. Anti-inflammatory mechanisms – https://pubmed.ncbi.nlm.nih.gov/19478309

5. Flavonoids in skin health (NIH) – https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3583891/

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