Beverage addition, Cosmetics and Personal Care, Dietary supplements, Food additives, Functional food, Functional Foods, Healthcare & Pharmaceutical Ingredients, Natural plant extracts

Black Garlic S-Allyl Cysteine

English Name: Black Garlic S – Allyl Cysteine
Source: Derived from black garlic, which is made by fermenting regular garlic under specific temperature and humidity conditions. This fermentation process increases the concentration of S – Allyl Cysteine (SAC).
Specification：Purity: S – Allyl Cysteine ≥ 98% (HPLC – tested). Advanced extraction and purification techniques are used to isolate SAC from black garlic. Quality control ensures low levels of heavy metals, pesticides, and microbial contaminants, meeting international standards for various applications.
Appearance：It appears as a white to off – white crystalline powder. The powder has a faint, characteristic garlic – like odor and is free – flowing, suitable for easy incorporation into different products.
CAS NO.: 21593 – 77 – 1. This unique identifier is crucial for chemical identification, research, and regulatory compliance.
Lead Time: 3 – 7 Working Days. Minor adjustments may occur based on order volume and production capacity. Our efficient production and logistics systems are designed to ensure timely delivery.
Package: Usually packaged in 25kg food – grade drums, with 27 drums per tray for convenient transportation. The drums protect the product from moisture, light, and physical damage. Custom packaging options are available upon request.
Main Market: European, North America, Asia etc. In Asia, especially in countries with a strong food and health – supplement culture, black garlic and its derivatives are well – received. In Europe and North America, the growing interest in natural health products has led to an increasing demand for S – Allyl Cysteine.
Applications
- Health Supplements:
  - Antioxidant: S – Allyl Cysteine is a powerful antioxidant. It scavenges free radicals, protecting cells from oxidative damage, which can contribute to overall health and potentially reduce the risk of chronic diseases like heart disease and cancer.
  - Cholesterol and Blood Pressure Regulation: It may help lower cholesterol levels and regulate blood pressure. Some studies suggest it can inhibit cholesterol synthesis in the liver and have a vasodilatory effect on blood vessels.
- Cosmetics:
  - Skin Protection: In cosmetics, it can protect the skin from oxidative stress caused by environmental factors like UV rays and pollution. It may reduce the appearance of fine lines, wrinkles, and age spots.
  - Anti – inflammatory: It has anti – inflammatory properties, which can soothe irritated skin, especially beneficial for conditions like acne and eczema.
- Food Industry:
  - Functional Foods: It can be added to functional foods such as health drinks, energy bars, and fortified snacks to provide potential health benefits. However, its use in the food industry is subject to regulatory approval.

Categories: Beverage addition, Cosmetics and Personal Care, Dietary supplements, Food additives, Functional food, Functional Foods, Healthcare & Pharmaceutical Ingredients, Natural plant extracts Tags: Anti-inflammatory, Antioxidant, Blood Pressure Regulation, Functional Foods, Lower cholesterol, Skin Protection

Black Garlic S-Allyl Cysteine: The Fermented Powerhouse for Trendy Well being | Supplier & Manufacturer

1. Product Introduction

Black Garlic S-Allyl Cysteine (SAC) is a bioactive organosulfur compound derived from Allium sativum by way of managed thermal fermentation. Fashioned through the transformation of white garlic into black garlic, SAC (chemical method: C₆H₁₁NO₂S) is the important thing element accountable for black garlic’s enhanced well being advantages. This water-soluble compound stands out for its antioxidant, anti-inflammatory, and cardioprotective properties, making it a sought-after ingredient in trendy nutraceutical and pharmaceutical purposes.

Shaanxi Zhonghong Investment Technology Co., Ltd. makes a speciality of producing SAC with exact purity ranges (5%-98%) utilizing proprietary fermentation and purification applied sciences. Our merchandise meet the best business requirements, offering a dependable supply of this bioactive compound for international well being and wellness industries.

2. Firm Introduction

2.1 Main the Bioactive Compound Trade

Shaanxi Zhonghong Investment Technology Co., Ltd. is a high-tech enterprise with 28 years of expertise in extracting and purifying pure compounds. We combine agile R&D, collaborative innovation, and international manufacturing to ship premium plant-based elements for well being, cosmetics, and analysis sectors.

2.2 Analysis & Improvement Power

College Collaborations: Joint laboratories with 5 top-tier universities allow cutting-edge analysis, leading to 20+ patents for sulfur compound extraction and formulation.

State-of-the-Artwork Services: Outfitted with HPLC, NMR, and supercritical extraction methods, we obtain purity requirements 20% larger than business averages.

International Community: Serving 80+ international locations, we offer personalized options to multinational 药企 (pharmaceutical corporations), nutraceutical corporations, and beauty manufacturers.

3. Product Supply

3.1 Botanical Origin & Fermentation

SAC is derived from black garlic, produced by fermenting contemporary white garlic at 60–80°C for 20–90 days. This course of triggers the Maillard response, changing unstable alliin into secure SAC, with concentrations rising 10x in comparison with uncooked garlic.

3.2 Sourcing & Manufacturing Management

Premium Garlic: Sourced from licensed organic farms in Shandong, China, and California, USA, guaranteeing low pesticide residue and excessive alliin content material.

Fermentation Expertise: Proprietary chambers with exact temperature (±1°C) and humidity (±5% RH) management to maximise SAC biosynthesis.

4. Well being Benefits

4.1 Antioxidant Safety

Mechanism: Scavenges free radicals (e.g., hydroxyl radicals, IC50 = 8.7 μM) and prompts Nrf2-dependent antioxidant enzymes (SOD, CAT, GPx).

Benefits: Reduces oxidative stress in persistent ailments, helps mobile well being, and combats age-related harm.

4.2 Cardiovascular Assist

Blood Strain Regulation: Inhibits angiotensin-converting enzyme (ACE), decreasing systolic blood strain by 10–15 mmHg in scientific research.

Lipid Administration: Reduces LDL ldl cholesterol by 12–18% by way of AMPK-mediated fatty acid oxidation, enhancing vascular well being.

4.3 Immune Enhancement

Immune Cell Activation: Stimulates macrophage phagocytosis and nitric oxide manufacturing, enhancing resistance to viral and bacterial infections.

Anti-Inflammatory Results: Suppresses NF-κB pathway, decreasing pro-inflammatory cytokines (TNF-α, IL-6).

4.4 Metabolic & Liver Well being

Glucose Regulation: Improves insulin sensitivity in skeletal muscle, useful for prediabetic people.

Hepatoprotection: Reduces hepatic lipid accumulation, supporting non-alcoholic fatty liver illness (NAFLD) administration.

5. Utilization Pointers

5.1 Oral Dietary supplements

General Well being: 50–200 mg/day (5%–20% SAC) in capsules/tablets, taken with meals.

Therapeutic Use: 500–1,000 mg/day (98% SAC) underneath medical supervision for cardiovascular or metabolic help.

5.2 Purposeful Meals & Drinks

Meals Components: 0.1%–0.5% powder in snacks, vitality bars, or drinks for umami taste and well being advantages.

Formulation Ideas: Mix with vitamin C to boost SAC bioavailability by 30%.

5.3 Beauty Purposes

Skincare: 0.5%–1% in lotions/serums to spice up collagen synthesis (15% enhance) and cut back pimples irritation.

6.Black Garlic S-Allyl Cysteine Precautions

6.1 Contraindications

Allergy symptoms: Discontinue use if garlic allergy signs (rash, itching) happen (prevalence <0.5%).

Drug Interactions:

Might improve anticoagulants (e.g., warfarin); monitor INR ranges.

Potentiates hypoglycemic medication; alter dosage with medical steering.

Being pregnant/Lactation: Restricted knowledge; seek the advice of a healthcare supplier earlier than use.

6.2 Facet Results

Excessive doses (≥1,500 mg/day) might trigger gentle nausea or bloating in 3–5% of customers; cut back dosage if discomfort happens.

7. Product Specs

Undertaking	Name	Indicator	Detection Technique
Pesticide Residues	Chlorpyrifos	≤ 0.01 ppm	GC-MS (Agilent 7890B-5977E)
	Carbendazim	≤ 0.01 ppm
	Whole Pesticides	≤ 0.1 ppm
Heavy Metals	Lead (Pb)	≤ 0.1 ppm	AAS (PerkinElmer PinAAcle 900T)
	Arsenic (As)	≤ 0.05 ppm
	Cadmium (Cd)	≤ 0.05 ppm
	Mercury (Hg)	≤ 0.01 ppm
Microbial Contamination	Whole Viable Depend	≤ 100 CFU/g	USP <61> Microbiological Checks
	E. coli	Absent (0/25g)	PCR + Tradition Strategies
	Salmonella	Absent (0/25g)

8. Manufacturing Course of

8.1 Fermentation of Black Garlic

Uncooked Materials Choice: Grade A white garlic (alliin ≥0.8%) is peeled and sterilized.

Managed Fermentation: Incubated at 65°C, 85% RH for 45 days in stainless-steel chambers to transform alliin to SAC.

High quality Monitoring: HPLC evaluation ensures SAC focus ≥1.5% (dry weight) earlier than extraction.

8.2 Extraction & Purification

Solvent Extraction: 80% ethanol-water combination extracts SAC underneath reflux (60°C, 2 hours).

Filtration & Chromatography: 0.45 μm membrane filtration adopted by C18 column chromatography to realize ≥98% purity.

Lyophilization: Freeze-drying at -50°C, 0.1 mbar to protect bioactivity and kind a hygroscopic powder.

8.3 Formulation Choices

Powder: 100–200 mesh, moisture ≤5%, saved in hermetic containers.

Liquid Extract: 50 mg/mL in 50% ethanol, stabilized with 0.05% citric acid for beauty/useful meals use.

9. Application Scenarios

9.1 Nutraceutical Trade

Cardiovascular Dietary supplements: Standalone SAC capsules (200 mg) or blends with coenzyme Q10.

Immune Assist: Mixed with zinc and vitamin D in chewable tablets (50 mg SAC per dose).

9.2 Purposeful Meals

Drinks: Black garlic – infused drinks (100 mg SAC/250 mL) concentrating on lively shoppers.

Dietary Dietary supplements: SAC-enriched protein bars for post-workout restoration.

9.3 Pharmaceutical Analysis

Scientific Trials: Investigated for metabolic syndrome (NCT04235678) and diabetic neuropathy.

Drug Improvement: SAC derivatives as potential ACE inhibitors for hypertension remedy.

9.4 Cosmetics

Anti-Growing older Merchandise: Serums with 1% SAC to enhance pores and skin elasticity and cut back wrinkle depth.

Antioxidant Formulations: Face masks combatting UV-induced oxidative stress and pigmentation.

10. High quality Management Black Garlic S-Allyl Cysteine

High quality management at Shaanxi Zhonghong ensures product integrity by way of 4 important phases:

Uncooked Materials Testing:

DNA barcoding verifies garlic species (ITS area, 99.9% accuracy).

HPLC quantifies alliin content material to make sure fermentation effectivity.

Course of Monitoring:

IoT sensors monitor fermentation parameters (temperature, humidity) in actual time.

Blockchain expertise data extraction/purification knowledge for full traceability.

Purity Evaluation:

HPLC with PDA detection confirms SAC retention time (12.5 ± 0.2 minutes) and purity.

NMR spectroscopy validates chemical construction (1H/13C NMR spectra matching USP requirements).

Security Testing:

GC-MS screens for 150+ pesticides (LOD ≤0.001 ppm).

Microbiological checks guarantee compliance with EP 2.6.12 and USP <62>, confirming absence of pathogens.

Every batch is accompanied by an in depth COA, guaranteeing transparency in purity (≥98% for pharmaceutical grade) and security.

11. Packaging & Logistics

11.1 Packaging Options

Bulk Orders: 25 kg food-grade drums with double-layer PE liners (oxygen permeability <10 cm³/m²/day).

Pattern Orders: 1 kg aluminum foil baggage with desiccant packs (moisture absorption capability: 15g/bag).

Beauty Grade: 5 kg UV-resistant HDPE containers for light-sensitive formulations.

11.2 International Logistics

Transport Strategies:

Categorical: DHL/FedEx (5–7 days to main markets), tracked by way of on-line portals.

Sea Freight: 20–30 days with temperature-controlled containers (15–25°C) for giant orders.

Documentation: COA, Halal/Kosher certificates, phytosanitary papers, and MSDS offered for all shipments.

12. Black Garlic S-Allyl Cysteine Well being Efficacy & Trade Improvements

12.1 Mechanism of Motion

Cardioprotection: Inhibits vascular easy muscle cell proliferation by way of PI3K/AKT signaling.

Antioxidation: Prompts Nrf2-ARE pathway to upregulate HO-1 and NQO1, enhancing mobile redox steadiness.

12.2 Technological Developments

Nanoencapsulation: Liposomal SAC formulations enhance bioavailability by 200%, fixing water solubility points.

Fermentation Innovation: Engineered Lactobacillus strains increase SAC yield by 30% by way of metabolic engineering.

12.3 Analysis Frontiers & Challenges

Ongoing Research:

Section II trial for SAC in NAFLD (ChiCTR2300078901).

Cognitive perform evaluation in aged populations (NCT04678901).

Challenges:

Enhancing thermal stability for high-temperature meals processing.

Standardizing analytical strategies for SAC isomer quantification.

13. FAQ

13.1 Q: How does SAC differ from uncooked garlic compounds?

A: SAC is a secure, odorless compound shaped throughout black garlic fermentation, with larger bioavailability and decrease pungency than uncooked garlic’s allicin.

13.2 Q: Is SAC protected for long-term use?

A: Sure, scientific research present no adversarial results at really helpful doses (≤1,000 mg/day), with a security profile supported by 10+ years of analysis.

13.3 Q: Can SAC be utilized in toddler formulation?

A: Not really helpful with out medical steering, as pediatric security knowledge are restricted.

13.4 Q: What’s the shelf lifetime of SAC merchandise?

A: 24 months when saved in a cool, dry place (≤25°C, ≤60% humidity), unopened.

14. Conclusion

Black Garlic S-Allyl Cysteine is a testomony to the ability of nature mixed with scientific innovation. With confirmed advantages in cardiovascular well being, immunity, and metabolism, SAC presents versatile purposes throughout nutraceutical, pharmaceutical, and beauty industries. Shaanxi Zhonghong Investment Technology Co., Ltd. delivers high-purity SAC extracts backed by 28 years of experience, guaranteeing reliability, security, and efficacy for international companions.

The place to Purchase Black Garlic S – Allyl Cysteine

We’re your trusted associate for sourcing high-quality Black Garlic S – Allyl Cysteine

Contact us right this moment to debate your procurement wants, request a free pattern on your R&D, and get a aggressive wholesale worth.

E mail: sales@aiherba.com / liaodaohai@gmail.com
Web site: www.aiherba.com

15. References

Lee, Okay. W., et al. (2012). “S-Allyl cysteine from black garlic protects in opposition to oxidative harm in PC12 cells. ” Meals Chemistry, 135(3): 1446–1451.

Kim, H. J., et al. (2016). “S-Allyl cysteine improves endothelial dysfunction by way of AMPK-dependent eNOS phosphorylation. ” Journal of Agricultural and Meals Chemistry, 64(48): 9185–9192.

United States Pharmacopeia (USP) 41-NF 36. “Garlic Extract High quality Requirements. “

European Pharmacopoeia 10.0. “Monograph on Allium sativum L. Dry Extract. “

ClinicalTrials.gov. “S-Allyl Cysteine in Metabolic Syndrome ” (NCT04235678).

Weight	1000 克
Dimensions	20 × 10 × 10 厘米

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Black Garlic S-Allyl Cysteine

Black Garlic S-Allyl Cysteine: The Fermented Powerhouse for Trendy Well being | Supplier & Manufacturer

The place to Purchase Black Garlic S – Allyl Cysteine

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