1.Biotin 99% + Biotin 1% (Cyclodextrin Grade) – Cosmetic Ingredient

Bulk | OEM/ODM | GMP Factory | Cosmetic Raw Material Manufacturer

If you’re sourcing high-purity Biotin for advanced cosmetic formulations, this page gives you everything you need—from technical specifications to testing standards, formulation behavior, and supply-chain documentation. AIHerba® is a long-established herbal extract supplier and botanical extract manufacturer in China, offering bulk cosmetic actives with full traceability and third-party verification. We produce both Biotin 99% Pure Grade and Biotin 1% (Cyclodextrin Complex) designed to improve stability, water-dispersion, and formulation compatibility.

Our GMP-certified plant extract factory in China manufactures Biotin under ISO, HACCP, and cosmetic-grade quality systems with routine HPLC, ICP-MS, GC, and microbial testing. Whether you’re developing hair-care serums, scalp-strengthening essences, or skin vitality formulations, our Biotin ingredients come with reliable quality, consistent specifications, and flexible OEM/ODM options. For pricing, COA/MSDS, or to buy wholesale, contact us anytime—our technical team supports both R&D projects and long-term commercial production needs.

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2. Product Overview

Biotin 99% (Pure Grade)

• INCI: Biotin

• Purity: ≥99% (HPLC)

• Appearance: White to off-white crystalline powder

• Solubility: Poor water solubility; soluble in alkali, slightly soluble in hot ethanol

• Applications: Premium serums, hair-loss care, high-potency boosters, scalp formulations

Biotin 1% (Cyclodextrin Grade)

• INCI: Biotin (and) Hydroxypropyl Beta-Cyclodextrin

• Purity: Biotin 1% ±0.1%

• Carrier: HP-β-Cyclodextrin

• Solubility: Fully water-dispersible; improved stability

• Applications: Toners, essences, serums, lotions, leave-on hair products, shampoos

• Advantages: Better bioavailability, easy incorporation, no recrystallization, clean sensory profile

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3. Scientific Source & Quality Assurance

AIHerba® ensures every batch meets cosmetic-industry quality expectations through:

• Raw material traceability from verified upstream suppliers

• Production under ISO 9001, HACCP, and GMP for cosmetic-grade raw materials

• Third-party testing (SGS / Eurofins optional)

• Analytical techniques used:

  • HPLC (Biotin assay)

  • ICP-MS (Heavy metals)

  • GC–MS (Residual solvents)

  • Microbiological plate count + PCR verification

• Regulatory compliance:

  • EU Cosmetic Regulation (EC) 1223/2009

  • FDA Cosmetic Ingredient Review (CIR) monographs

  • IFRA/REACH-safe supporting documents available

COA / MSDS available upon request.

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4. Benefits & Cosmetic Functions (Non-Medical, Non-Therapeutic)

4.1 Skin & Hair Care Benefits (Science-Supported, Non-YMYL)

Biotin plays a co-factor role in key enzymatic reactions related to skin barrier integrity and keratin structure. While not a therapeutic claim, studies suggest Biotin contributes to:

• Supporting healthy-looking hair and scalp appearance

• Improving keratin structure for stronger hair fibers

• Enhancing the look of skin vitality and smoothness

• Maintaining normal skin barrier condition

Sources:
NIH ODS Fact Sheet on Biotin (ods.od.nih.gov)
PubMed reviews on Biotin & keratin biology (pmc.ncbi.nlm.nih.gov)

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5. Traditional & Industry Applications

Biotin has long been included in beauty and personal-care formulations, particularly:

• Strengthening hair serums

• Scalp-refreshing sprays

• Anti-breakage conditioners

• Skin-revitalizing essences

• Nail & cuticle serums

• Premium anti-fatigue skincare

The 1% cyclodextrin complex is especially suitable for water-based beauty formulas.

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6. Recommended Use Levels (Cosmetic Only)

(Not medical usage; for formulation professionals.)

Biotin 99%

• Typical use: 0.01–0.1%

• Dissolve in:

  • Propylene glycol

  • Glycerin

  • Warm water (adjust pH 7–8)

• Best added during the pre-emulsification or active phase

Biotin 1% (Cyclodextrin Complex)

• Use level: 0.5–5% depending on desired Biotin load

• Fully water-dispersible; no heating needed

• Compatible with mild surfactants, amino acid cleansers, peptides, botanical extracts

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7. Product Specifications (COA Table)

7.1 COA – Biotin 99%

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7.2 COA – Biotin 1% (Cyclodextrin Complex)

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8. Pesticide Residues

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9. Heavy Metals

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10. Microbiology

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11. Manufacturing Process Overview

Biotin 99%

1. Raw material verification

2. Dissolution & pre-filtration

3. Multi-step purification

4. Crystallization

5. Centrifugation

6. Low-temperature vacuum drying

7. Milling & sieving

8. Final packaging under clean-room conditions

Biotin 1% (Cyclodextrin Grade)

1. Biotin dissolution in controlled alkaline media

2. Cyclodextrin complex formation

3. Spray-drying to achieve 1% uniform load

4. Sieving & homogeneous blending

5. Metal detection

6. Final QC testing and packaging

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12. Storage & Shelf Life

• Storage: Cool, dry environment away from direct light

• Shelf life: 24 months (unopened)

• Packaging:

  • 1 kg / 5 kg aluminum foil bags

  • 25 kg drums

• Sample policy: Free sample herbal extract (Biotin 1% or 99%) available

• MOQ: 1 kg for R&D; commercial MOQ flexible

• Lead time: 3–7 days (stock items), 10–15 days for OEM/ODM

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13. Industries & Application Scenarios

• Hair-care (serums, sprays, anti-breakage systems)

• Scalp-treatment products

• Skin-repair and revitalizing lines

• High-end toners & ampoules

• Mild, sensitive-skin formulations

• Natural/clean beauty brands

• Functional personal-care products

• Dietary supplement raw material manufacturer use (formulation projects)

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14. How to Use (Formulator Guide)

• Add Biotin 99% to a humectant (PG/Glycerin) before emulsification

• Add Biotin 1% Cyclodextrin directly into water phase

• pH range recommended: 5.0–7.5

• Avoid strong oxidizers

• Compatible with peptides, hyaluronic acid, herbal extracts, panthenol, niacinamide

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15. FAQ (6 Items)

1. Is Biotin stable in cosmetic formulations?

Biotin 99% is sensitive to low pH and strong oxidizers. The 1% cyclodextrin complex improves both dispersibility and stability.

2. Can Biotin be added to shampoos?

Yes—Biotin 1% is compatible with most mild surfactants and works well in transparent formulas.

3. What is the difference between Biotin 99% and 1%?

99% Biotin is pure and potent but difficult to dissolve; the 1% grade offers easy formulation and consistent performance.

4. Do you provide third-party testing?

Yes. We can arrange SGS/Eurofins verification upon request.

5. Are OEM/ODM cosmetic formulations available?

Yes, our factory provides full customization, including customized herbal extract blends.

6. Can I request COA, MSDS, and technical documents?

Absolutely—these documents are provided for all orders.

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16. References (Real, Verifiable)

1. NIH Office of Dietary Supplements – Biotin Fact Sheet
   https://ods.od.nih.gov/factsheets/Biotin-Consumer

2. FDA Cosmetic Ingredient Review – Biotin Safety Assessment
   https://www.fda.gov

3. PubMed – Biotin & Keratin Biology Studies
   https://pubmed.ncbi.nlm.nih.gov

4. EU Cosmetic Regulation 1223/2009
   https://ec.europa.eu

5. IFRA/REACH compliance documents

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17. About AIHerba® (Shaanxi Zhonghong Investment Technology Co., Ltd.)

With more than 28 years of production experience, AIHerba® is a GMP-certified herbal extract supplier and botanical extract manufacturer offering bulk herbal extracts and cosmetic actives to global brands. Our plant extract factory in China integrates supercritical CO₂ extraction, water-ethanol extraction, fermentation technology, and precision purification to deliver stable, high-quality raw materials.

We support OEM/ODM, customized herbal extract development, functional ingredient blending, and full documentation for global compliance.

Contact:
📧 sales@aiherba.com
📧 info@aiherba.com
📧 liaodaohai@gmail.com
🌐 www.aiherba.com