1. Biotin (Vitamin B7) Cosmetic Grade Supplier & Manufacturer | GMP Factory | Bulk / Wholesale D-Biotin 99% & Water-Dispersible 1%
As a GMP-certified manufacturer and bulk supplier, AIHerba provides cosmetic grade Biotin (Vitamin B7 / D-Biotin) for hair and scalp formulations where procurement teams require stable batches, clear specifications, and audit-ready documentation. We supply D-Biotin 99% high-purity powder and a water-dispersible Biotin 1% (cyclodextrin complex) designed for easier handling in water-based systems such as shampoos and scalp tonics. Each batch is supported by COA, MSDS/SDS, specification sheet, and batch traceability, with optional third-party testing. If you are sourcing for OEM/ODM, private label, or contract manufacturing projects, request pricing, MOQ, lead time, and packaging options from our sales team.
CTA: Request Biotin bulk quotation → get COA + MSDS + lead time within 24 business hours.
Quick Summary
- Ingredient name: Biotin (Vitamin B7), D-Biotin
- CAS No.: 58-85-5
- Main applications: shampoo, conditioner, scalp serum/tonic, hair mask, leave-in hair care; (secondary) dietary supplement premix & functional food fortification (market-dependent)
- Typical purity: ≥99.0% (D-Biotin powder); 1.0% Biotin (water-dispersible cyclodextrin complex)
- Suitable industries: cosmetics & personal care, OEM/ODM factories, ingredient distributors; (secondary) supplement/food manufacturers (grade & compliance on request)
2. What Is Biotin (Vitamin B7)?
Biotin (also known as Vitamin B7 or Vitamin H) is a sulfur-containing, water-soluble vitamin used as a functional ingredient across cosmetics and nutrition supply chains. In cosmetics, Biotin is commonly used for hair and scalp care positioning (e.g., “hair conditioning” support), while procurement teams typically focus on purity, solubility/dispersion behavior, and documentation (COA/MSDS).
Benefits (Regulatory-Safe, Cosmetic Context)
- Commonly used in hair/scalp products to support conditioning and appearance-focused claims (claim language must follow local cosmetic regulations).
- Offers two sourcing choices for formulators: high-purity D-Biotin 99% or water-dispersible biotin 1% for easier processing in aqueous systems.
- Suitable for manufacturers needing specification control, batch consistency, and QC traceability.
Applications (Primary: Cosmetics; Secondary: Supplement/Food)
Cosmetics / Personal Care
- Shampoos & conditioners (rinse-off)
- Scalp tonics / scalp serums / sprays (leave-on)
- Hair masks / treatments
- Hair-care emulsions and clear systems (with suitable dispersion strategy)
Dietary Supplement / Functional Food (Secondary, on request)
- Premix and fortification applications may be feasible depending on target market requirements, grade selection (USP/EP/FCC), and regulatory compliance.
Dosage / Specification (Procurement-Friendly)
- Form options:
- D-Biotin 99% powder (high purity, limited water solubility)
- Water-dispersible Biotin 1% (cyclodextrin complex) (improved dispersion in water phase)
- Molecular weight: 244.31 g/mol
- Labeling (cosmetic): INCI: Biotin (confirm via your market’s labeling rules)
Safety
- This ingredient page is for raw material sourcing. It does not provide medical advice and does not claim to diagnose, treat, cure, or prevent disease.
- Finished product manufacturers are responsible for safety assessment, stability testing, microbiological control, claims substantiation, and regulatory filings for each target market.
Supplier / Manufacturer (B2B Buyer Focus)
AIHerba supports B2B procurement with:
- Bulk / wholesale supply and stable lot management
- COA, MSDS/SDS, technical specifications, and traceability
- Optional third-party testing and buyer-specific QC limits
- Support for OEM/ODM workflows (documentation, sampling, packaging, logistics coordination)
CTA: Ask for Biotin supplier pricing, MOQ, and COA → sales@aiherba.com
3. Detailed Technical Specifications
Product Identification Table
| Parameter | D-Biotin 99% (Cosmetic Grade) | Water-Dispersible Biotin 1% (Cyclodextrin Complex) |
|---|---|---|
| Product name | Biotin / Vitamin B7 / D-Biotin | Biotin 1% (cyclodextrin complex), water-dispersible |
| CAS No. | 58-85-5 | 58-85-5 (biotin component) |
| Molecular formula | C10H16N2O3S | Blend (contains biotin) |
| Molecular weight | 244.31 g/mol | N/A (blend) |
| Appearance | White to off-white powder | White to off-white powder |
| Typical assay | ≥99.0% (HPLC) | 1.0% biotin (HPLC) |
| Solubility / handling | Limited water solubility | Improved dispersion in water phase |
| Suggested use | Concentrates, premixes, controlled dispersion systems | Shampoos, tonics, aqueous serums, easier processing |
| Documents | COA / MSDS / Spec Sheet | COA / MSDS / Spec Sheet |
Recommended on-page image alt text (for your CMS)
- Alt 1: “Biotin (Vitamin B7) D-Biotin 99% powder bulk wholesale packaging for cosmetic manufacturers”
- Alt 2: “Water-dispersible Biotin 1% cyclodextrin complex dispersion in water phase for shampoo formulation”
- Alt 3: “Biotin supplier COA HPLC assay and batch traceability documentation for B2B procurement”
4. Product Source & Raw Material Origin
Biotin (D-Biotin) is an industrially produced vitamin ingredient. For professional buyers, “origin” typically refers to:
- Manufacturing route control (validated SOPs, controlled purification steps)
- Incoming raw material qualification (approved suppliers, identity checks)
- Contaminant risk management (residual solvents screening, metals, microbiology)
- Batch traceability (lot records, retain samples)
If your procurement SOP requires specific statements (e.g., allergen, GMO, animal-derived materials, irradiation), request the documentation package during RFQ.
5. Mechanism of Action & Functional Properties (Non-Medical)
From a functional ingredient perspective, biotin is a cofactor involved in biochemical carboxylation pathways. In cosmetics, it is typically positioned as:
- A hair/scalp care supportive ingredient used in rinse-off and leave-on applications
- A vitamin active that can be included in multi-active hair formulas (e.g., panthenol + niacinamide + caffeine + biotin) for product positioning
Important: cosmetic use is about formulation role and consumer-perceivable positioning, not medical outcomes.
6. Application-Relevant Benefits (Regulatory-Safe)
For cosmetic formulators and OEM/ODM factories, biotin may support:
- Hair feel and conditioning positioning in shampoos/conditioners (rinse-off)
- Scalp care positioning in tonics/serums (leave-on), subject to local claim rules
- Premium “vitamin complex” narratives when used with other B-vitamins and humectants
Claim compliance note: Use “commonly used for,” “may support,” “helps maintain the appearance of,” and avoid disease language.
7. Usage Guidelines & Formulation Recommendations
Choosing the Right Grade (Procurement + R&D)
- Choose D-Biotin 99% when your R&D team has a defined dispersion strategy and needs high purity for concentrated premixes or specialized systems.
- Choose Water-dispersible Biotin 1% when you want faster processing, better handling in water phase, or improved uniformity in shampoos/tonics.
Practical Formulation Notes (Non-Exhaustive)
- Processing: Prefer adding during cool-down when possible; avoid unnecessary long high-temperature exposure.
- Solubility: 99% biotin has limited water solubility—verify clarity, precipitation risk, and uniformity in pilot batches.
- Stability: Validate with your system’s pH, surfactants, solvents, and preservatives via stability testing (appearance, odor, pH, microbial control).
- Compatibility: Run a small compatibility screen if you use strong oxidizers or reactive actives.
CTA: Send your formula type + target pH + process steps to get a grade recommendation and biotin MOQ/price quote.
8. Traditional & Modern Industrial Applications
Modern cosmetics
- Hair care (shampoo/conditioner/mask)
- Scalp care (tonics/serums/sprays)
- “Vitamin active complex” positioning in premium personal care
Industrial supply chains
- Ingredient distribution (bulk repacking under controlled conditions)
- OEM/ODM factories needing spec consistency + documentation readiness
- (Secondary) supplement/food fortification workflows where buyers request USP/EP/FCC alignment and regulatory confirmation
9. COA & Quality Control Specifications
Below is a typical QC framework used for B2B procurement. Actual limits can be customized to your market, customer specs, and regulatory pathway.
9.1 Pesticide Residue Screen (Multi-Residue)
| Pesticide item | Limit | Test method |
|---|---|---|
| Organochlorine pesticides (sum) | NMT 0.05 mg/kg | GC-MS/MS |
| DDT (sum of isomers) | NMT 0.01 mg/kg | GC-MS/MS |
| BHC (sum of isomers) | NMT 0.01 mg/kg | GC-MS/MS |
| Aldrin + Dieldrin (sum) | NMT 0.01 mg/kg | GC-MS/MS |
| Heptachlor + epoxide (sum) | NMT 0.01 mg/kg | GC-MS/MS |
| Chlorpyrifos | NMT 0.01 mg/kg | GC-MS/MS |
| Malathion | NMT 0.02 mg/kg | GC-MS/MS |
| Diazinon | NMT 0.02 mg/kg | GC-MS/MS |
| Carbendazim | NMT 0.02 mg/kg | LC-MS/MS |
| Multi-residue panel (as required) | Complies | LC-MS/MS / GC-MS/MS |
9.2 Heavy Metals
| Heavy metal item | Limit | Test method |
|---|---|---|
| Lead (Pb) | NMT 1.0 mg/kg | ICP-MS |
| Arsenic (As) | NMT 1.0 mg/kg | ICP-MS |
| Cadmium (Cd) | NMT 0.5 mg/kg | ICP-MS |
| Mercury (Hg) | NMT 0.1 mg/kg | ICP-MS |
| Nickel (Ni) (optional, for sensitive markets) | NMT 1.0 mg/kg | ICP-MS |
9.3 Microbiological Limits — Typical (Raw Material Control)
| Microbiology item | Limit | Test method |
|---|---|---|
| Total aerobic microbial count (TAMC) | NMT 1,000 CFU/g | ISO 21149 / USP <61> |
| Total yeast & mold count (TYMC) | NMT 100 CFU/g | ISO 16212 / USP <61> |
| E. coli | Absent / 1 g | USP <62> / ISO methods |
| Salmonella | Absent / 10 g | USP <62> / ISO methods |
| Staphylococcus aureus | Absent / 1 g | USP <62> / ISO methods |
| Pseudomonas aeruginosa | Absent / 1 g | USP <62> / ISO methods |
Documentation offered (typical): COA, MSDS/SDS, Spec Sheet, batch traceability statement, export docs, and optional third-party lab report.
10. Manufacturing Process & Production Flow
Biotin is typically produced via controlled industrial synthesis routes followed by purification and crystallization. A procurement-oriented production flow looks like this:
- Incoming raw material qualification (supplier approval + identity checks)
- Controlled synthesis steps under validated SOPs
- Purification (impurity control strategy aligned with intended grade)
- Crystallization & filtration (purity and particle handling)
- Drying & milling/sieving (as required for handling)
- In-process QC (critical checkpoints)
- Final QC release (assay by HPLC, metals, microbiology per buyer requirements)
- Packaging in moisture-barrier materials with lot labeling
- Retain samples + batch traceability archiving
For water-dispersible Biotin 1%: a controlled blending/complexing step is added, followed by uniformity testing and dispersion performance checks.
11. Storage, Shelf Life & Packaging
- Storage: Keep sealed, cool, dry, away from moisture and direct sunlight.
- Shelf life: Typically 24 months under recommended storage (confirm on batch COA).
- Packaging (common for bulk orders): 1 kg / 5 kg / 10 kg aluminum foil bags; 25 kg fiber drums (custom options available).
Packaging image alt text: “Biotin 99% bulk packaging 25 kg fiber drum for wholesale cosmetic ingredient supply”
12. MOQ, Sample Policy & Global Shipping
MOQ (Long-Tail Purchase Intent Keywords)
- MOQ: from 1 kg for R&D trials (subject to stock and project profile)
- Production bulk quantities available for OEM/ODM factories and distributors.
Sample Policy
- Samples may be available for qualified B2B buyers. Request COA + sample policy with company information and application details.
Global Shipping
- Export-ready documentation support (invoice, packing list, COO if required).
- Common Incoterms: EXW / FOB / CIF / DDP (destination dependent).
CTA: Request biotin bulk price, lead time, and shipping terms → sales@aiherba.com
13. Clinical Data & Scientific Research (Reference-Only; No Medical Conclusions)
For buyers working across both cosmetics and nutrition categories, the following publications are commonly cited in discussions about biotin and hair/nail contexts. These are provided for reference only and do not imply medical claims for cosmetic products.
- Reviews note that biotin deficiency can be associated with hair/nail changes, while evidence for routine high-dose supplementation in non-deficient populations is limited.
- Biotin is a well-recognized micronutrient with established dietary reference discussions and safety notes, including potential interference with certain laboratory tests at high supplemental intakes.
(See references in Section 19.)
14. Applicable Industries
- Cosmetics & personal care manufacturers (hair/scalp care focus)
- OEM/ODM factories (shampoo/conditioner/serum production)
- Ingredient importers, wholesalers, and distributors
- Contract manufacturing and private label brands
- (Secondary, on request) dietary supplement / functional food manufacturers (grade & compliance confirmation required)
15. Industry Application Scenarios (Real B2B Use Cases)
- OEM Shampoo Factory (Southeast Asia) — “Water-Phase Friendly Vitamin Active”
Buyer needed a vitamin active that disperses reliably in a surfactant base without visible specks. They selected water-dispersible Biotin 1%, requested COA/MSDS, and used a standard incoming QC plan (assay + micro + metals) for production release. - EU Hair-Care Brand (Private Label) — “Documentation-First Procurement”
Brand’s compliance team required an audit-ready pack: spec sheet, COA, SDS, traceability statement, and consistent lot format. They sourced D-Biotin 99% for controlled premix manufacturing and performed stability testing in their final formula under EU cosmetic compliance workflow. - Distributor (Middle East) — “Bulk/Wholesale Repacking Program”
Distributor purchased bulk drums for repacking into smaller B2B units under controlled conditions. Key procurement drivers were lot consistency, lead time, and wholesale pricing, with optional third-party testing for key customers.
16. Supplier Comparison & Procurement Guide
When evaluating a biotin supplier / manufacturer for cosmetics, professional buyers typically compare:
- Grade clarity & intended use
- Cosmetic grade vs supplement grade (USP/EP/FCC alignment). Avoid suppliers that blur grades without documentation.
- Assay method & impurity controls
- Ask for assay method (commonly HPLC) and impurity profile controls relevant to your market.
- Handling performance
- If your system is water-based, confirm whether you need water-dispersible biotin (e.g., cyclodextrin complex) and request a dispersion test note.
- QC documentation & traceability
- COA completeness, batch numbering, retain samples, and change control.
- Commercial terms (purchase-intent long tail)
- MOQ, lead time, biotin bulk price, packaging, Incoterms, and sample policy.
Procurement checklist CTA: Email your checklist request: “Biotin CAS 58-85-5 — need COA, MSDS, MOQ, price, lead time” → sales@aiherba.com
17. FAQ for B2B Buyers (6)
1) Are you a biotin manufacturer or trading company?
We operate as a GMP-certified manufacturer (and support global B2B supply). For audits, request our company profile and quality documentation pack.
2) What is your standard biotin purity and test method?
D-Biotin powder is typically ≥99.0% (commonly tested by HPLC). Full specification and COA are available on request.
3) What is the difference between D-Biotin 99% and water-dispersible biotin 1%?
99% is a high-purity powder with limited water solubility; the 1% cyclodextrin complex is designed for easier dispersion in water-based cosmetic systems.
4) What is your MOQ and lead time for bulk orders?
MOQ often starts from 1 kg for R&D; bulk orders depend on stock and volume. Request a quotation to confirm current lead time.
5) Can you provide COA, MSDS/SDS, and third-party testing?
Yes. COA and SDS are standard; third-party testing can be arranged per buyer requirements.
6) Can biotin be used for dietary supplements or food fortification?
Potentially, depending on grade selection and your target market’s regulatory requirements. Share your market and compliance needs for confirmation.
18. Internal Links & Related Ingredients (Recommended)
To strengthen topical authority for “hair & scalp actives,” link this page internally to related ingredients :
- Panthenol (Pro-Vitamin B5) — recommended anchor: “panthenol supplier for hair care”
- Niacinamide (Vitamin B3) — recommended anchor: “niacinamide cosmetic grade manufacturer”
- Caffeine — recommended anchor: “caffeine ingredient for scalp products bulk”
- Zinc PCA — recommended anchor: “zinc pca supplier for scalp care”
19. References & Regulatory Sources (for Trust & Compliance)
(URLs are provided in code formatting so your team can copy into the page or compliance docs.)
Chemical identity / molecular data
- PubChem Compound Summary (Biotin, CID 171548):
https://pubchem.ncbi.nlm.nih.gov/compound/171548
Cosmetic regulation (EU)
- EU Cosmetics Regulation (EC) No 1223/2009 (EUR-Lex):
https://eur-lex.europa.eu/eli/reg/2009/1223/oj/eng - European Commission CosIng database (ingredient inventory / labeling reference):
https://ec.europa.eu/growth/tools-databases/cosing/
Cosmetic GMP guidance
- ISO 22716:2007 (Cosmetics — GMP guidelines):
https://www.iso.org/standard/36437.html
Nutrition / safety references (secondary category; not cosmetic claims)
- NIH Office of Dietary Supplements — Biotin Fact Sheet (Health Professionals):
https://ods.od.nih.gov/factsheets/Biotin-HealthProfessional/ - FDA brief on biotin interference with certain lab tests (high supplemental intake context):
https://www.fda.gov/news-events/fda-brief/fda-brief-fda-reminds-patients-health-care-professionals-and-laboratory-personnel-about-potential
Scientific literature (reference-only)
- “The Role of Vitamins and Minerals in Hair Loss: A Review” (PMC):
https://pmc.ncbi.nlm.nih.gov/articles/PMC6380979/ - “Brittle nails: response to daily biotin supplementation” (PMID: 8477615):
https://europepmc.org/abstract/med/8477615
Manufacturer & Quality Assurance (Fixed Closing Module)
Manufactured by AIHerba® (Shaanxi Zhonghong Investment Technology Co., Ltd.),
a GMP-certified manufacturer specializing in high-purity botanical extracts
for dietary supplements, cosmetics, and pharmaceutical applications.
✔ GMP-certified production facility
✔ Full COA & technical specifications available
✔ Batch traceability & strict quality control
✔ Bulk supply & OEM/ODM services for global B2B buyers
📧 sales@aiherba.com
| info@aiherba.com
| liaodaohai@gmail.com
🌐 www.aiherba.com
If you are looking for a bulk supplier / OEM manufacturer of Biotin (Vitamin B7), contact us for specifications, COA, and pricing.
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