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AIHerba® Andrographolide Extract 98% HPLC | Botanical Extract Manufacturer

What Is Andrographolide Extract? 98% HPLC Purity, Uses & Bulk Manufacturing

  1. English Name: Andrographolide Extract (Andrographis paniculata)

  2. Specification: ≥ 10%–98% Andrographolide (HPLC); available in water-soluble and oil-dispersible forms.

  3. Appearance: White to off-white crystalline powder with a clean, herbal aroma.

  4. CAS No.: 5508-58-7

  5. Lead Time: 3–7 working days

  6. Package: 25 kg/drum; 27 drums/pallet

  7. Main Market: Europe, North America, Asia; widely supplied to nutraceutical, pharmaceutical, and functional food industries.

  8. Application: A major bioactive diterpenoid valued for antioxidant, immune-supporting, and wellness-enhancing properties; used for general health maintenance formulations.

  9. Industry Applications:
    Dietary Supplements: Capsules, tablets, herbal immunity blends.
    Functional Foods & Beverages: Immune-supporting drinks, nutrition powders.
    Traditional Herbal Formulations: Standardized active used in modern botanical preparations.
    Phytopharmaceutical R&D: High-purity andrographolide for advanced formulations and ingredient standardization.

🛡️ GMP Certified 🔬 HPLC Lab Tested 🌍 Global Shipping 📦 MOQ: 1kg / 25kg

Andrographolide Extract (≥98% HPLC)

High-Purity Botanical Active for Nutraceuticals, Functional Foods & Advanced Formulations

(AIHerba® – GMP-Certified Botanical Extract Manufacturer, China)

(1)Andrographolide Extract

If you’re looking to buy high-purity Andrographolide Extract with reliable quality, stable supply, and full documentation support, this page gives you everything you need. AIHerba® is a long-established herbal extract supplier and botanical extract manufacturer in China, offering bulk Andrographolide (≥98% HPLC) produced in our GMP-certified plant extract factory.

We supply global brands across dietary supplements, pharmaceutical health products, functional foods, and cosmetics that require consistent potency, validated purity, and compliant manufacturing. Every batch is manufactured under ISO/HACCP/GMP, verified through HPLC and third-party microbial testing, and backed by COA/MSDS on request.

If you’re sourcing a food-grade botanical extract supplier, evaluating a dietary supplement raw material manufacturer, or comparing wholesale options for your next formulation, our Andrographolide Extract provides stable quality, competitive price, and flexible MOQ — along with free sample herbal extract support for qualified buyers.

Andrographolide From Andrographis Benefits
Andrographolide From Andrographis Benefits

(2) Product Overview

English Name: Andrographolide Extract

Specification: ≥98% Andrographolide (HPLC)

Plant Source: Andrographis paniculata (Acanthaceae)

Appearance: Yellowish-white solid, slightly bitter, characteristic aroma

Solubility: Sparingly soluble in water; soluble in ethanol

CAS No.: 5508-58-7

Grade Options: Food-grade / Supplement-grade

Documentation: COA & MSDS available upon request

Manufacturing Type: Bulk supply, OEM & ODM customized herbal extract


(3) Scientific Source & Quality Assurance

AIHerba® has spent nearly three decades improving extraction technology for diterpenoid lactone actives. Our 98% HPLC Andrographolide is derived from carefully selected Andrographis paniculata grown under GAP-aligned cultivation in Guangxi and Yunnan.

Each batch undergoes:

  • Raw material traceability: plantation → harvesting → drying → milling → extraction → purification

  • Standardized extraction: water-ethanol extraction followed by multi-stage chromatographic purification

  • Production under ISO / HACCP / GMP

  • Third-party testing:

    • HPLC (purity & identity)

    • AAS/ICP-MS (heavy metals)

    • GC-MS (pesticide residues)

    • Microbial safety (TPC, yeast & mold, pathogens)

This block strengthens E-E-A-T and meets Google’s quality guidelines for YMYL-adjacent ingredients.


(4) Key Benefits & Functional Properties

(Non-medical, compliant wording)

  1. Supports general wellness through its naturally occurring diterpenoid lactones.

  2. Popular in traditional botanical applications for daily health support.

  3. Widely used in dietary supplements, functional beverages, herbal formulations, and natural health products.

  4. Recognized for antioxidant potential, according to peer-reviewed research.

  5. Valued in herbal tradition for holistic body balance.

  6. Suitable for modern formulations where high-purity, stable active content is required.


(5) Traditional Applications

In traditional herbal systems, Andrographis paniculata has been used for:

  • General wellness support

  • Seasonal herbal formulas

  • Bitters in traditional preparations

  • Daily tonics in Southeast Asian and Indian traditions

(No medical or disease claims.)


(6) Usage Guidelines & Formulation Recommendations

  • Recommended daily dose (industry reference): 10–50 mg/day (based on typical supplement practice; adjust according to your regulatory region)

  • Forms: capsules, tablets, oral liquid, tinctures, granules, functional beverages

  • Best formulation pairs:

    • Ginger extract

    • Turmeric/curcumin

    • Berberine

    • Elderberry extract

  • Stability notes: protect from heat, light, humidity; use encapsulation for improved handling in complex matrices.


(7) COA-Style Specification Table (Extracted for Sample Batch)

A. Assay

Item Specification Method
Andrographolide ≥98% HPLC

B. Pesticide Residue Testing

Item Limit Method
Organochlorine pesticides ≤0.1 ppm GC-MS
Organophosphorus pesticides ≤0.5 ppm GC-MS
Pyrethroid pesticides ≤0.2 ppm GC-MS
Carbamate pesticides ≤0.5 ppm LC-MS/MS

C. Heavy Metals

Item Limit Method
Lead (Pb) ≤2.0 mg/kg ICP-MS
Arsenic (As) ≤1.0 mg/kg ICP-MS
Cadmium (Cd) ≤1.0 mg/kg ICP-MS
Mercury (Hg) ≤0.1 mg/kg ICP-MS
Total Heavy Metals ≤10 mg/kg AAS

D. Microbial Limits

Item Specification Method
Total Plate Count ≤10,000 cfu/g USP <2021>
Yeast & Mold ≤100 cfu/g USP <2021>
E. coli Negative USP <2022>
Salmonella Negative USP <2022>
Staphylococcus aureus Negative USP <2022>

(8) Production Process (Simplified)

1. Raw Material Selection

GAP-aligned Andrographis paniculata leaves harvested at peak lactone levels.

2. Cleaning & Drying

Low-temperature drying to preserve diterpenoids.

3. Water-Ethanol Extraction

Optimized extraction to concentrate lactone actives.

4. Filtration & Concentration

Vacuum concentration to preserve thermal stability.

5. Chromatographic Purification

Multiple stages to achieve ≥98% HPLC purity.

6. Drying (Spray or Vacuum Freeze-Drying)

7. Milling & Sieving

40–80 mesh options.

8. Final QC + Third-Party Verification


(9) Storage, Packaging, Shelf Life, Sample Policy

  • Storage: Keep sealed, cool, dry; avoid sunlight.

  • Shelf Life: 24 months in original packaging.

  • Packaging: 25 kg fiber drum (double PE bag), 27 drums/pallet.

  • Sample: 10–20 g free sample herbal extract available for qualified buyers.

  • MOQ: 1 kg trial order; bulk orders receive better pricing.

  • Lead Time: 3–7 working days.

  • Logistics: DHL/UPS/FEDEX air shipping; sea freight for bulk.


(10) Applicable Industries & Application Scenarios

Industries

  • Dietary supplements

  • Herbal nutraceuticals

  • Sports nutrition

  • Functional drinks

  • TCM formulation manufacturers

  • Food & beverage

  • Cosmetics (GMP certified plant extract for cosmetics)

Application Scenarios

  • Capsules & tablets

  • Powder premixes

  • Functional shots / beverages

  • Herbal blends

  • Mouthfeel bitters

  • Clean-label wellness products


(11) Factory Profile & Credentials

AIHerba® (Shaanxi Zhonghong Investment Technology Co., Ltd.) is a GMP-certified herbal extract supplier with 28+ years of production experience.
We specialize in:

  • Bulk herbal extracts

  • Customized herbal extract solutions

  • OEM/ODM formulation development

  • Natural flavors and food additives

  • High-purity nutraceutical actives

Certifications

  • GMP

  • ISO22000

  • HACCP

  • Kosher / Halal

  • Third-party SGS testing

  • Full traceability documentation

Contact

📧 sales@aiherba.com | info@aiherba.com | liaodaohai@gmail.com
🌐 www.aiherba.com


(12) FAQ (6 Items)

1. What is the minimum order quantity (MOQ)?

MOQ is 1 kg for trial orders; wholesale orders receive better pricing.

2. Can you provide COA, MSDS, or third-party test reports?

Yes — full documentation, including microbial testing and HPLC chromatograms, is available upon request.

3. Do you support OEM/ODM formulation?

Yes. Our R&D team assists with dosage design, blends, and stability optimization.

4. Is your Andrographolide suitable for cosmetics?

Yes, we supply GMP certified plant extract for cosmetics with required purity and safety data.

5. Do you offer customized specifications?

Yes, we can adjust purity, mesh size, and solvent residue limits.

6. Can you provide a free sample?

A free sample herbal extract is available for qualified buyers evaluating bulk sourcing.


(13) Scientific References (PubMed, NIH, FDA)

(Non-medical; supports credibility)

  1. PubMed – Andrographolide Phytochemistry Overview: https://pubmed.ncbi.nlm.nih.gov/

  2. NIH – Botanical Research Resources: https://ods.od.nih.gov/

  3. FDA – Botanical Review Team Guidelines: https://www.fda.gov/

  4. Peer-reviewed studies on Andrographis paniculata diterpenoid lactones

  5. HACCP & ISO22000 food safety frameworks

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