Andrographolide Extract (≥98% HPLC)
High-Purity Botanical Active for Nutraceuticals, Functional Foods & Advanced Formulations
(AIHerba® – GMP-Certified Botanical Extract Manufacturer, China)
(1)Andrographolide Extract
If you’re looking to buy high-purity Andrographolide Extract with reliable quality, stable supply, and full documentation support, this page gives you everything you need. AIHerba® is a long-established herbal extract supplier and botanical extract manufacturer in China, offering bulk Andrographolide (≥98% HPLC) produced in our GMP-certified plant extract factory.
We supply global brands across dietary supplements, pharmaceutical health products, functional foods, and cosmetics that require consistent potency, validated purity, and compliant manufacturing. Every batch is manufactured under ISO/HACCP/GMP, verified through HPLC and third-party microbial testing, and backed by COA/MSDS on request.
If you’re sourcing a food-grade botanical extract supplier, evaluating a dietary supplement raw material manufacturer, or comparing wholesale options for your next formulation, our Andrographolide Extract provides stable quality, competitive price, and flexible MOQ — along with free sample herbal extract support for qualified buyers.

(2) Product Overview
English Name: Andrographolide Extract
Specification: ≥98% Andrographolide (HPLC)
Plant Source: Andrographis paniculata (Acanthaceae)
Appearance: Yellowish-white solid, slightly bitter, characteristic aroma
Solubility: Sparingly soluble in water; soluble in ethanol
CAS No.: 5508-58-7
Grade Options: Food-grade / Supplement-grade
Documentation: COA & MSDS available upon request
Manufacturing Type: Bulk supply, OEM & ODM customized herbal extract
(3) Scientific Source & Quality Assurance
AIHerba® has spent nearly three decades improving extraction technology for diterpenoid lactone actives. Our 98% HPLC Andrographolide is derived from carefully selected Andrographis paniculata grown under GAP-aligned cultivation in Guangxi and Yunnan.
Each batch undergoes:
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Raw material traceability: plantation → harvesting → drying → milling → extraction → purification
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Standardized extraction: water-ethanol extraction followed by multi-stage chromatographic purification
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Production under ISO / HACCP / GMP
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Third-party testing:
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HPLC (purity & identity)
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AAS/ICP-MS (heavy metals)
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GC-MS (pesticide residues)
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Microbial safety (TPC, yeast & mold, pathogens)
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This block strengthens E-E-A-T and meets Google’s quality guidelines for YMYL-adjacent ingredients.
(4) Key Benefits & Functional Properties
(Non-medical, compliant wording)
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Supports general wellness through its naturally occurring diterpenoid lactones.
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Popular in traditional botanical applications for daily health support.
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Widely used in dietary supplements, functional beverages, herbal formulations, and natural health products.
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Recognized for antioxidant potential, according to peer-reviewed research.
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Valued in herbal tradition for holistic body balance.
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Suitable for modern formulations where high-purity, stable active content is required.
(5) Traditional Applications
In traditional herbal systems, Andrographis paniculata has been used for:
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General wellness support
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Seasonal herbal formulas
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Bitters in traditional preparations
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Daily tonics in Southeast Asian and Indian traditions
(No medical or disease claims.)
(6) Usage Guidelines & Formulation Recommendations
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Recommended daily dose (industry reference): 10–50 mg/day (based on typical supplement practice; adjust according to your regulatory region)
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Forms: capsules, tablets, oral liquid, tinctures, granules, functional beverages
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Best formulation pairs:
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Ginger extract
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Turmeric/curcumin
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Berberine
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Elderberry extract
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Stability notes: protect from heat, light, humidity; use encapsulation for improved handling in complex matrices.
(7) COA-Style Specification Table (Extracted for Sample Batch)
A. Assay
| Item | Specification | Method |
|---|---|---|
| Andrographolide | ≥98% | HPLC |
B. Pesticide Residue Testing
| Item | Limit | Method |
|---|---|---|
| Organochlorine pesticides | ≤0.1 ppm | GC-MS |
| Organophosphorus pesticides | ≤0.5 ppm | GC-MS |
| Pyrethroid pesticides | ≤0.2 ppm | GC-MS |
| Carbamate pesticides | ≤0.5 ppm | LC-MS/MS |
C. Heavy Metals
| Item | Limit | Method |
|---|---|---|
| Lead (Pb) | ≤2.0 mg/kg | ICP-MS |
| Arsenic (As) | ≤1.0 mg/kg | ICP-MS |
| Cadmium (Cd) | ≤1.0 mg/kg | ICP-MS |
| Mercury (Hg) | ≤0.1 mg/kg | ICP-MS |
| Total Heavy Metals | ≤10 mg/kg | AAS |
D. Microbial Limits
| Item | Specification | Method |
|---|---|---|
| Total Plate Count | ≤10,000 cfu/g | USP <2021> |
| Yeast & Mold | ≤100 cfu/g | USP <2021> |
| E. coli | Negative | USP <2022> |
| Salmonella | Negative | USP <2022> |
| Staphylococcus aureus | Negative | USP <2022> |
(8) Production Process (Simplified)
1. Raw Material Selection
GAP-aligned Andrographis paniculata leaves harvested at peak lactone levels.
2. Cleaning & Drying
Low-temperature drying to preserve diterpenoids.
3. Water-Ethanol Extraction
Optimized extraction to concentrate lactone actives.
4. Filtration & Concentration
Vacuum concentration to preserve thermal stability.
5. Chromatographic Purification
Multiple stages to achieve ≥98% HPLC purity.
6. Drying (Spray or Vacuum Freeze-Drying)
7. Milling & Sieving
40–80 mesh options.
8. Final QC + Third-Party Verification
(9) Storage, Packaging, Shelf Life, Sample Policy
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Storage: Keep sealed, cool, dry; avoid sunlight.
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Shelf Life: 24 months in original packaging.
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Packaging: 25 kg fiber drum (double PE bag), 27 drums/pallet.
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Sample: 10–20 g free sample herbal extract available for qualified buyers.
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MOQ: 1 kg trial order; bulk orders receive better pricing.
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Lead Time: 3–7 working days.
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Logistics: DHL/UPS/FEDEX air shipping; sea freight for bulk.
(10) Applicable Industries & Application Scenarios
Industries
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Dietary supplements
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Herbal nutraceuticals
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Sports nutrition
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Functional drinks
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TCM formulation manufacturers
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Food & beverage
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Cosmetics (GMP certified plant extract for cosmetics)
Application Scenarios
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Capsules & tablets
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Powder premixes
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Functional shots / beverages
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Herbal blends
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Mouthfeel bitters
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Clean-label wellness products
(11) Factory Profile & Credentials
AIHerba® (Shaanxi Zhonghong Investment Technology Co., Ltd.) is a GMP-certified herbal extract supplier with 28+ years of production experience.
We specialize in:
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Bulk herbal extracts
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Customized herbal extract solutions
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OEM/ODM formulation development
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Natural flavors and food additives
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High-purity nutraceutical actives
Certifications
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GMP
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ISO22000
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HACCP
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Kosher / Halal
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Third-party SGS testing
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Full traceability documentation
Contact
📧 sales@aiherba.com | info@aiherba.com | liaodaohai@gmail.com
🌐 www.aiherba.com
(12) FAQ (6 Items)
1. What is the minimum order quantity (MOQ)?
MOQ is 1 kg for trial orders; wholesale orders receive better pricing.
2. Can you provide COA, MSDS, or third-party test reports?
Yes — full documentation, including microbial testing and HPLC chromatograms, is available upon request.
3. Do you support OEM/ODM formulation?
Yes. Our R&D team assists with dosage design, blends, and stability optimization.
4. Is your Andrographolide suitable for cosmetics?
Yes, we supply GMP certified plant extract for cosmetics with required purity and safety data.
5. Do you offer customized specifications?
Yes, we can adjust purity, mesh size, and solvent residue limits.
6. Can you provide a free sample?
A free sample herbal extract is available for qualified buyers evaluating bulk sourcing.
(13) Scientific References (PubMed, NIH, FDA)
(Non-medical; supports credibility)
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PubMed – Andrographolide Phytochemistry Overview: https://pubmed.ncbi.nlm.nih.gov/
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NIH – Botanical Research Resources: https://ods.od.nih.gov/
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FDA – Botanical Review Team Guidelines: https://www.fda.gov/
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Peer-reviewed studies on Andrographis paniculata diterpenoid lactones
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HACCP & ISO22000 food safety frameworks
Bulk Supply & Technical Support
Get direct factory quotes, COA, and MSDS within 12 hours. We support bulk supply and custom specifications.






