What Is Ammonium Glycyrrhizinate?
Ammonium Glycyrrhizinate is a natural compound derived from licorice root (Glycyrrhiza glabra), a well-known medicinal herb used in both Traditional Chinese Medicine (TCM) and modern pharmaceuticals. This plant extract is the ammonium salt form of glycyrrhizic acid, which is responsible for the sweet taste and many of the biological activities of licorice.
In its refined form, Ammonium Glycyrrhizinate is often used as a cosmetic ingredient, food additive, and dietary supplement due to its strong anti-inflammatory, antioxidant, and skin-soothing properties. As a herbal extract powder, it is widely applied in cosmetics, beverages, pharmaceuticals, and health supplements.
At Shaanxi Zhonghong Investment Technology Co., Ltd., we supply high-quality Ammonium Glycyrrhizinate produced under strict GMP standards. Our factory offers customized herbal extract solutions, bulk wholesale, and free sample services for international buyers at aiherba.com.
Key Ingredients and Composition
Each batch of Ammonium Glycyrrhizinate is extracted from premium-grade licorice roots using advanced water and ethanol extraction techniques. The active component is glycyrrhizic acid ammonium salt, which typically appears as a white to light yellow crystalline powder.
Typical Specifications:
- Assay: ≥98% purity
- Appearance: White crystalline powder
- Solubility: Freely soluble in water
- Origin: Licorice root (Glycyrrhiza glabra L.)
- CAS No.: 53956-04-0
Efficacy and Health Benefits
Ammonium Glycyrrhizinate is highly valued for its pharmacological and cosmetic benefits:
- Anti-inflammatory effects – Helps reduce redness, swelling, and irritation in skin and mucous membranes.
- Skin-soothing properties – Ideal for cosmetic products targeting sensitive, dry, or acne-prone skin.
- Antioxidant activity – Protects cells from oxidative stress and premature aging.
- Liver protection – May assist in detoxification and prevent liver cell damage.
- Immune regulation – Supports a balanced immune response.
- Flavor enhancer – Used as a natural sweetener and flavoring agent in food and beverages.
- Anti-allergic effects – Reduces symptoms associated with allergies and skin irritation.
These properties make it a multifunctional plant extract used in personal care formulations, pharmaceuticals, and functional foods.
How Effective Is It?
Scientific studies show that Ammonium Glycyrrhizinate can effectively modulate inflammatory mediators such as prostaglandins and cytokines, helping to reduce inflammation and irritation. Its bioavailability and skin penetration make it especially effective in cosmetic creams, gels, and lotions.
When used orally (in supplements or beverages), it may help with liver health, detoxification, and immune balance, though dosage should follow professional recommendations for safety.
How to Take It and Recommended Dosage
Dosage Guidelines:
- Cosmetic use: 0.1%–0.5% in formulations (cream, lotion, serum).
- Dietary supplement: Typically 50–200 mg per day, depending on formulation.
- Food additive: As a natural flavoring agent or sweetener, follow local regulatory limits.
Always consult a professional before use in pharmaceutical or nutraceutical applications.
Side Effects and Precautions
Ammonium Glycyrrhizinate is generally safe when used within the recommended range. However, excessive use may lead to:
- Water retention
- Elevated blood pressure
- Potassium imbalance
Precautions:
- Avoid high doses during pregnancy or for individuals with hypertension or kidney disease.
- For cosmetic use, always conduct a patch test before full application.
Who Can Use It?
This versatile herbal extract is suitable for:
- Cosmetic manufacturers seeking natural anti-inflammatory actives.
- Food and beverage producers looking for natural flavoring ingredients.
- Nutraceutical companies developing detox or liver-support supplements.
- Pharmaceutical formulators for anti-inflammatory or hepatoprotective drugs.
Factory Direct Supply & Customization
As a GMP-certified herbal extract factory, Shaanxi Zhonghong Investment Technology Co., Ltd. provides:
- Bulk Ammonium Glycyrrhizinate powder
- OEM/ODM services
- Customized purity levels
- Free sample service
- Global shipping and stable supply
We specialize in organic plant extracts, customized herbal extracts, and functional ingredient solutions for cosmetics, food additives, and dietary supplements.
📧 Contact us:
- Email: sales@aiherba.com, info@aiherba.com, liaodaohai@gmail.com
- Website: www.aiherba.com
FAQs about Ammonium Glycyrrhizinate
1. What is Ammonium Glycyrrhizinate used for?
It’s mainly used in cosmetics, foods, and supplements for its anti-inflammatory and flavor-enhancing effects.
2. Is it safe for daily use?
Yes, when used within standard dosage ranges and according to local regulatory guidelines.
3. Can I get a free sample before bulk purchase?
Yes, aiherba.com provides free sample herbal extracts for qualified buyers.
4. Do you offer OEM or customized specifications?
Absolutely. We support customized herbal extracts according to purity, particle size, or formulation needs.
5. Where can I buy Ammonium Glycyrrhizinate in bulk?
You can order directly from Shaanxi Zhonghong Investment Technology Co., Ltd., a professional herbal extract manufacturer and supplier at aiherba.com.
Summary
Ammonium Glycyrrhizinate is a versatile, high-value plant extract offering strong anti-inflammatory and antioxidant properties for a wide range of cosmetic, food, and health supplement applications. Backed by GMP-certified production and customized solutions, Shaanxi Zhonghong Investment Technology Co., Ltd. stands as your trusted Ammonium Glycyrrhizinate supplier for bulk and wholesale orders worldwide.
References:
- European Journal of Pharmacology – Anti-inflammatory mechanism of Glycyrrhizic acid derivatives.
- Food Chemistry – Natural sweetness and antioxidant function of licorice extracts.
- Cosmetics & Toiletries Science Applied – Applications of Glycyrrhizinate in skincare.