Ammonium Glycyrrhizinate – Premium Pharmaceutical & Cosmetic Ingredient
1. Product Overview
Ammonium Glycyrrhizinate, a derivative of licorice root (Glycyrrhiza glabra), is a high-purity, water-soluble compound widely used in cosmetics, pharmaceuticals, and functional foods. Known for its anti-inflammatory, soothing, and flavor-enhancing properties, it is a trusted ingredient in skin care formulations and dietary products.
2. Source & Production
Botanical Source: Extracted from the roots of Glycyrrhiza glabra (licorice).
Production Process:

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Raw Material Selection: High-quality licorice roots are sourced from certified farms.
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Extraction: Roots are cleaned, crushed, and extracted using water-alcohol solution under controlled temperature.
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Purification: Multi-step crystallization and filtration ensure high purity.
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Ammonium Salt Formation: Glycyrrhizic acid is neutralized with ammonium hydroxide.
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Drying & Milling: Product is spray-dried and milled to uniform powder.
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Quality Control: COA verification, microbial and heavy metal testing.
3. Benefits & Applications
3.1 Functional Benefits
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Anti-inflammatory & Soothing: Ideal for skin irritation, redness, and sensitive skin formulations.
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Sweetener & Flavor Enhancer: Enhances taste in beverages and confectionery.
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Antioxidant Properties: Protects cells from oxidative stress.
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Synergistic Effects: Works well with herbal extracts and cosmetic actives.
3.2 Health Benefits
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Supports gastrointestinal health and liver function
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Reduces skin inflammation in dermatological products
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Enhances immune support in dietary supplements
3.3 Industry Applications
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Cosmetics & Personal Care: Soothing creams, anti-redness serums, lip balms
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Pharmaceuticals: Lozenges, cough syrups, anti-inflammatory formulations
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Nutraceuticals & Functional Foods: Sweeteners, flavor enhancers, health supplements
4. Recommended Usage
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Cosmetic Formulations: 0.1–1.0%
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Pharmaceutical Applications: 0.5–2.0%
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Food & Beverage: Up to 0.5% (per regulatory guidelines)
Best Practices: Dissolve fully in warm water before adding to final formulation. Avoid prolonged exposure to high temperatures to maintain efficacy.
5. COA & Product Specifications
| Category | Item | Specification | Test Method |
|---|---|---|---|
| Chemical Properties | Purity | ≥ 98% | HPLC |
| Appearance | Yellowish-white crystalline powder | Visual | |
| Solubility | Soluble in water | USP | |
| Pesticide Residues | Total Pesticides | ≤ 0.01% | GC-MS / HPLC |
| Specific Pesticides | Comply with EU & US standards | GC-MS | |
| Heavy Metals | Lead (Pb) | ≤ 2 ppm | ICP-MS |
| Arsenic (As) | ≤ 1 ppm | ICP-MS | |
| Mercury (Hg) | ≤ 0.1 ppm | ICP-MS | |
| Cadmium (Cd) | ≤ 1 ppm | ICP-MS | |
| Microbiological | Total Plate Count | ≤ 1000 CFU/g | AOAC 990.12 |
| Yeast & Mold | ≤ 100 CFU/g | USP <61> | |
| E. coli | Negative | USP <62> | |
| Salmonella | Negative | USP <62> |
6. Storage & Shelf Life
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Storage Conditions: Store in a cool, dry place away from direct sunlight and moisture.
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Shelf Life: 24 months when stored in original sealed packaging.
7. Packaging & Shipping
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Standard Packaging: 25 kg/drum, 27 drums per pallet
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Sample Policy: Small samples available for quality evaluation
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Shipping: Air, sea, or express courier
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MOQ: 100 kg (customizable for bulk orders)
8. Recommended Formulation Guidelines
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Cosmetics: Pair with allantoin, hyaluronic acid, and plant extracts for soothing skin care.
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Food & Beverage: Compatible with sugar substitutes and natural flavors.
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Pharmaceuticals: Stabilizes active compounds in syrups and lozenges.
9. Certifications & Quality Assurance
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ISO 9001 / GMP Certified Factory
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Third-Party Testing Reports Available
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Compliance: EU, FDA, and WHO guidelines
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COA & MSDS Provided
10. Professional Experience & Client Cases
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15+ Years Manufacturing Experience: Supplying global cosmetic and pharmaceutical industries
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Customer Applications: Leading European skincare brands, North American nutraceutical companies, and Asian pharmaceutical manufacturers
11. FAQ
Q1: Is Ammonium Glycyrrhizinate safe for sensitive skin?
A1: Yes, it is widely used in dermatological products for its soothing and anti-inflammatory properties.
Q2: Can it be used in beverages?
A2: Yes, it is water-soluble and can be used as a flavor enhancer within regulatory limits.
Q3: How should it be stored?
A3: Keep in a cool, dry place, sealed from moisture and sunlight.
Q4: Are COA and MSDS available?
A4: Yes, full documentation is provided for all batches.
12. References & Industry Standards
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FDA GRAS Notice: Glycyrrhizinate as food additive
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European Pharmacopeia: Ammonium Glycyrrhizinate specifications
Bulk Supply & Technical Support
Get direct factory quotes, COA, and MSDS within 12 hours. We support bulk supply and custom specifications.





