Alpha-Ketoglutarate (AKG) – High-Purity Nutraceutical Ingredient | AIHerba®
1. Alpha-Ketoglutarate (AKG) – Bulk Supplier & OEM Manufacturer
AIHerba® offers premium Alpha-Ketoglutarate (AKG) powder in bulk for nutraceuticals, functional foods, dietary supplements, and pharmaceutical R&D. Our GMP-certified factory ensures consistent purity, stability, and bioavailability, supported by detailed COA and regulatory compliance. With customizable packaging, OEM/ODM solutions, and fast global shipping, AIHerba is a trusted partner for international formulators seeking reliable bulk AKG suppliers from China. AKG is widely applied in sports nutrition, anti-aging formulations, and energy metabolism support. Whether sourcing for bulk production or research purposes, our traceable supply chain and professional technical support guarantee high-quality raw materials, transparent specifications, and optimized formulations.
2. What is Alpha-Ketoglutarate (AKG)
Alpha-Ketoglutarate (AKG, CAS No. 328-50-7) is a key intermediate in the citric acid (TCA) cycle, commonly used as a functional ingredient in nutraceuticals, dietary supplements, and sports nutrition products. AKG serves as a co-factor in amino acid metabolism and energy production. In industrial applications, AKG is supplied in high-purity powder form, suitable for customized formulations in bulk.
Synonyms: 2-Oxoglutaric acid, 2-Ketoglutaric acid, α-Ketoglutaric acid
Appearance: White to off-white crystalline powder
Solubility: Water-soluble, stable in pH 5–7
CAS Number: 328-50-7
3. Detailed Technical Specifications COA
| Parameter Category | Item | Specification | Test Method |
|---|---|---|---|
| Identity & Purity | Alpha-Ketoglutarate | ≥99% (HPLC) | HPLC |
| Moisture | Water Content | ≤0.5% | Karl Fischer Titration |
| pH (1% solution) | pH Value | 5.0–7.0 | pH Meter |
| Appearance | Powder Color | White to off-white | Visual |
| Odor | Characteristic | Characteristic | Organoleptic |
Pesticide Residues
| Name | Limit | Test Method |
|---|---|---|
| Organochlorine | ≤0.01 mg/kg | GC-MS |
| Organophosphate | ≤0.01 mg/kg | GC-MS |
| Pyrethroids | ≤0.01 mg/kg | GC-MS |
Heavy Metals
| Name | Limit | Test Method |
|---|---|---|
| Lead (Pb) | ≤2 ppm | ICP-MS |
| Arsenic (As) | ≤1 ppm | ICP-MS |
| Mercury (Hg) | ≤0.1 ppm | ICP-MS |
| Cadmium (Cd) | ≤1 ppm | ICP-MS |
Microbiological
| Name | Limit | Test Method |
|---|---|---|
| Total Plate Count | ≤1000 CFU/g | USP 61 |
| Yeast & Mold | ≤100 CFU/g | USP 61 |
| E. coli | Negative | USP 62 |
| Salmonella | Negative | USP 62 |
| Staphylococcus aureus | Negative | USP 62 |
4. Production Process
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Raw Material Sourcing – High-quality starting compounds sourced from GMP-compliant suppliers.
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Extraction / Crystallization – Controlled pH and temperature to ensure purity.
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Drying & Milling – Low-temperature vacuum drying to preserve stability.
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Screening & Sieving – Uniform particle size for powder consistency.
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Quality Control & Packaging – Batch testing per COA standards; GMP-approved packaging.
5. Storage & Shelf Life
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Storage Conditions: Cool, dry, and dark environment; airtight packaging.
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Shelf Life: 36 months from production date under recommended conditions.
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Packaging Options: 25kg/drum (customizable OEM packaging available).
6. Sample Policy & MOQ
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Sample Availability: Free sample available for testing; shipping cost borne by buyer.
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Minimum Order Quantity (MOQ): 1 kg for lab testing; bulk MOQ negotiable.
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Delivery Lead Time: 3–7 working days for sample, 7–15 days for bulk.
7. Mechanism of Action & Functional Benefits (Non-Therapeutic)
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Energy Metabolism Support: AKG acts as an intermediate in the TCA cycle to assist in cellular energy regulation.
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Amino Acid Synthesis: Supports glutamate and glutamine metabolism, enhancing nitrogen balance in formulations.
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Formulation Flexibility: Compatible with capsules, powders, and functional beverage formulations.
⚠ Avoiding health claims: Content is strictly informational and industrial-use oriented.
8. Recommended Usage & Formulation Guide
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Typical Dosage in Formulations: 1–5 g per serving (as functional ingredient; consult regulatory limits per region).
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Best Formulation Practices:
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Mix with amino acids or protein powders for sports nutrition products.
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Compatible with beverages, tablets, or capsules in pH 5–7.
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Store formulations in airtight, low-moisture conditions.
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9. Traditional & Industry Applications
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Sports Nutrition – Incorporated into energy powders and recovery supplements.
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Anti-Aging Nutraceuticals – Used in functional foods and beverages to support metabolism.
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Pharmaceutical & R&D – Raw material for laboratory studies, pharmaceutical excipients, and metabolic research.
10. Comparative & Purchasing Guide
| Supplier Feature | AIHerba | Typical Supplier | Notes |
|---|---|---|---|
| GMP Certification | ✅ | Variable | Ensures quality & traceability |
| COA & Testing | ✅ Comprehensive | Often limited | Heavy metals, pesticides, microbiology |
| OEM/ODM Service | ✅ Customizable | Rare | Supports private label & formulation |
| Lead Time | 3–7 days (sample) | 7–20 days | Faster delivery from China factory |
| Bulk MOQ | 1kg+ | 10–50kg | Flexibility for R&D and small orders |
Key Buyer Tip: Focus on traceable COA, GMP compliance, and OEM support to reduce procurement risk.
11. Industry Case Scenarios
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Global Sports Nutrition Brand: Formulated AKG powder into recovery supplements, verified via independent lab COA for EU market.
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Functional Beverage Company: Incorporated AKG into anti-aging drinks; OEM packaging and batch traceability supported global export.
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Pharmaceutical R&D Lab: Used AKG in metabolic studies and amino acid product development; AIHerba supplied small-batch GMP-certified raw material.
12. FAQ (Structured for Google Rich Results)
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Q: What is the purity of AIHerba Alpha-Ketoglutarate?
A: ≥99% by HPLC, GMP-certified with full COA. -
Q: Can you provide samples before bulk purchase?
A: Yes, free samples available; shipping cost paid by buyer. -
Q: What industries use Alpha-Ketoglutarate?
A: Sports nutrition, dietary supplements, functional foods, and pharmaceutical R&D. -
Q: What is the minimum order quantity (MOQ)?
A: 1 kg for sample; bulk MOQ is flexible and negotiable. -
Q: Are COA, heavy metals, and microbiological tests provided?
A: Yes, all batches include detailed testing reports and pesticide screening. -
Q: Can AIHerba provide OEM/ODM formulation support?
A: Yes, we provide full OEM/ODM services including custom packaging and formulation guidance.
13. References & Authoritative Sources
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FDA Dietary Supplement Guidelines: FDA DSHEA
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EU Nutraceutical Regulations: EFSA Guidance
14. Contact & Sourcing
AIHerba® | China Natural Plant Extract Supplier & OEM Factory
Shaanxi Zhonghong Investment Technology Co., Ltd. – GMP-certified
📧 sales@aiherba.com | info@aiherba.com | liaodaohai@gmail.com
🌐 www.aiherba.com
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Bulk and wholesale supply for cosmetics, nutraceuticals, functional foods, and dietary supplements
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OEM/ODM formulation support, traceable supply chain, fast delivery
