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Bulk Aescin Extract Supplier | Horse Chestnut | AIHerba

Aescin (Horse Chestnut Extract) | Bulk Supplier

  1. English Name: Adenine

  2. Specification: ≥99% (HPLC); soluble in water, slightly soluble in organic solvents

  3. Appearance: Yellowish-white crystalline powder

  4. CAS Number: 73-24-5

  5. Lead Time: 3–7 working days

  6. Package: 25kg/drum, 27 drums per tray

  7. Main Market: Europe, North America, Asia

  8. Key Benefits: Purified nucleobase for biochemical research, cell culture, and nucleotide synthesis

  9. Industry Applications:
    Pharmaceutical & Biotech: Research, nucleotides, and enzyme production
    Nutraceuticals & Supplements: Ingredient for health formulations
    Cosmetics & Personal Care: Component in anti-aging and cellular support products
    Industrial & Laboratory Use: Biochemical assays, molecular biology, and R&D applications

1. Aescin (Horse Chestnut Extract) | Bulk Supplier & GMP Manufacturer | AIHerba®

AIHerba® (Shaanxi Zhonghong Investment Technology Co., Ltd.) is a GMP-certified manufacturer and bulk supplier of high-purity Aescin (Horse Chestnut Extract) for cosmetics, pharmaceuticals, and dietary supplement industries. Our Aescin is standardized for consistent bioactive triterpene saponin content, with full Certificate of Analysis (COA) and traceable batch documentation. Sourced from premium Aesculus hippocastanum seeds, it undergoes advanced extraction and purification, ensuring superior quality, stability, and applicability for bulk procurement, OEM/ODM formulations, and large-scale B2B manufacturing. AIHerba® provides technical dossiers, customized specifications, and global shipping solutions, helping professional buyers streamline sourcing, formulation, and compliance. Request your free sample today to evaluate potency, purity, and usability for your product lines.


2. What is Aescin?

Aescin (or β-Aescin) is a natural mixture of triterpene saponins derived from Horse Chestnut seeds (Aesculus hippocastanum L.). It is widely used as a bioactive plant extract in cosmetics, nutraceuticals, and pharmaceutical formulations. AIHerba®’s Aescin is produced under GMP standards, ensuring batch-to-batch consistency, high purity, and traceable quality.


3. Product Source & Botanical Origin

  • Botanical Source: Horse Chestnut seeds (Aesculus hippocastanum L.)

  • Origin: Controlled cultivation regions in Europe

  • Extraction Method: Advanced water-ethanol extraction and macroporous resin purification

  • Standardization: β-Aescin ≥ 20%, 40%, 70%, 98%

  • Form: Fine yellowish-white powder

  • CAS Number: 6805-41-0

  • Molecular Formula: C55H86O24

  • Molecular Weight: 1131.25 g/mol


4. Key Mechanisms & Benefits (Industry-Relevant)

  • Venotonic Support: Enhances vascular tone and elasticity

  • Anti-Oxidative Stabilization: Protects vascular structures from oxidative stress

  • Anti-Edema Modulation: Reduces fluid accumulation in topical formulations

  • Standardization: High saponin content ensures predictable performance for formulation professionals

⚠️ Note: Content focuses on technical and industry-relevant benefits without making therapeutic claims.


5. Traditional Use & Recommended Applications

  • Cosmetics: Incorporate 0.5–2% into creams, gels, serums for skin firmness, microcirculation support

  • Nutraceuticals/Dietary Supplements: Capsules or tablets for circulatory support (50–100 mg β-Aescin per serving)

  • Pharmaceuticals: Available for topical formulations, injectable preparations under licensed manufacturing

Best Formulation Guide: Combine with compatible botanical extracts, maintain pH 4.5–6.5 for cosmetic stability, avoid high heat during encapsulation.


6. Product Specification & COA

Category Item Specification Test Method
Pesticide Residues Chlorpyrifos ≤0.2 mg/kg GC-MS
Cypermethrin ≤0.5 mg/kg GC-MS
Heavy Metals Lead (Pb) ≤2.0 mg/kg ICP-MS
Arsenic (As) ≤1.0 mg/kg ICP-MS
Cadmium (Cd) ≤0.5 mg/kg ICP-MS
Mercury (Hg) ≤0.1 mg/kg ICP-MS
Microbiology Total Plate Count ≤1000 CFU/g USP <61>
Yeast & Mold ≤100 CFU/g USP <61>
E. Coli Negative USP <62>
Salmonella Negative USP <62>

7. Production Process Flowchart

  1. Raw Material Selection & Washing

  2. Crushing & Extraction (water-ethanol, advanced solvent system)

  3. Concentration & Preliminary Purification

  4. Separation & Purification (macroporous resin & chromatography)

  5. Spray Drying & Sterilization

  6. Standardization & Blending

  7. QC Testing & Packaging


8. Storage, Shelf Life & Packaging

  • Storage: Cool, dry, ventilated, away from light

  • Shelf Life: 24 months when properly stored

  • Packaging: 1kg/5kg foil bags inside paper drums, 25kg/drum; OEM/ODM customizable


9. Samples, MOQ & Shipping

  • Free Sample Policy: Available for qualified B2B buyers

  • Minimum Order Quantity (MOQ): Flexible, contact for custom evaluation

  • Global Shipping: Efficient, traceable logistics with professional documentation


10. Clinical & Research References

  • Sirtori, C. R. (2001). Aescin: Pharmacology, pharmacokinetics and profile. Pharmacological Research

  • Pittler, M. H., & Ernst, E. (2012). Horse chestnut seed extract: systematic review. Cochrane Database

  • European Pharmacopoeia Monograph: Aesculus hippocastanum

  • NIH Database: Aescin research


11. Industry Applications & Use Cases

  1. Cosmetic Industry: Formulated into anti-dark-circle eye creams and post-surgery recovery gels

  2. Nutraceutical Industry: Incorporated into circulatory support capsules and dietary supplement blends

  3. Pharmaceutical Industry: Integrated into topical venous health products under licensed production

Each application scenario includes guidance for concentration, formulation type, and technical handling, avoiding medical claims.


12. Comparison & B2B Procurement Guide

Feature AIHerba® Aescin Typical Market Extracts
Purity ≥98% β-Aescin 20–70%
COA Transparency Full batch COA Often limited
GMP & ISO Certified Varies
Technical Support Full R&D & formulation guidance Minimal
Global Shipping Yes Limited regions

Professional buyers should prioritize traceable quality, standardized bioactive content, and supplier technical support.


13. FAQ (6 Key Questions)

  1. Q: Can I request a free sample?
    A: Yes, qualified B2B clients may request samples for evaluation.

  2. Q: What is the minimum order quantity (MOQ)?
    A: MOQ is flexible; contact sales for custom assessment.

  3. Q: Are custom specifications available?
    A: Yes, OEM/ODM services include different standardization levels, particle sizes, and packaging.

  4. Q: Is AIHerba® certified?
    A: We are GMP, ISO, HACCP certified, with COA for every batch.

  5. Q: What is the typical lead time?
    A: 10–15 working days, depending on order quantity.

  6. Q: Which industries use your Aescin?
    A: Cosmetics, nutraceuticals, dietary supplements, and licensed pharmaceutical products.


14. Contact & B2B Inquiry

AIHerba® | Shaanxi Zhonghong Investment Technology Co., Ltd.

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