, , , , , ,

Tetrandrine

  1. Product Overview
    English Name: Tetrandrine  Purity: Tetrandrine ≥ 98%
    Chemical Nature: It is a bisbenzylisoquinoline alkaloid, mainly isolated from the root of Stephania tetrandra, a traditional Chinese medicinal plant. It has attracted significant research attention due to its diverse pharmacological activities.
  2. Specification:Purity: Tetrandrine ≥ 98% (HPLC – tested). Stringent extraction and purification procedures are implemented to achieve and maintain this high level of purity. Stringent quality control measures are in place to limit heavy metals, pesticides, and microbial contaminants, conforming to international standards for pharmaceutical, cosmetic, and supplement use.
  3. Appearance:It appears as a white to off-white crystalline powder. The powder has a faint, characteristic odor and is free – flowing, making it easy to incorporate into various products.
  4. CAS NO.: 518 – 34 – 3. This unique identifier is crucial for chemical identification, research, and regulatory compliance.
  5. Lead Time: 3 – 7 Working Days. Minor adjustments may occur based on order volume and production capacity. Our efficient production and logistics systems are designed to ensure timely delivery.
  6. Package: 25kg/drum, with 27 drums/tray. The drums are made of food – grade materials, providing excellent protection against moisture, light, and physical damage during storage and transportation. Custom packaging options are available upon request.
  7. Main Market: European, North America, Asia etc. It has a global market presence. In Asia, especially in China where traditional Chinese medicine has a long history, it has been used for centuries. In Europe and North America, it is increasingly being studied and incorporated into various products due to its potential health benefits.
  8. Applications
    • Health Supplements:
      • Anti – inflammatory: Tetrandrine exhibits potent anti – inflammatory effects. It can inhibit the production of inflammatory mediators, which is beneficial for conditions like arthritis, asthma, and inflammatory bowel disease. By reducing inflammation, it helps alleviate pain and discomfort.
      • Cardiovascular Health: Some studies suggest it may have a role in regulating blood pressure. It can relax blood vessels, improving blood flow and potentially reducing the risk of hypertension and related cardiovascular problems.
      • Anti – fibrotic: It shows promise in preventing and treating fibrotic diseases. It can inhibit the excessive deposition of extracellular matrix proteins, which is crucial in conditions like liver fibrosis and pulmonary fibrosis.
    • Cosmetics:
      • Skin Soothing: Its anti – inflammatory properties make it effective in calming irritated skin. It can reduce redness, itching, and inflammation associated with skin conditions like acne, eczema, and psoriasis.
      • Anti – aging: By protecting skin cells from oxidative stress, it helps reduce the appearance of fine lines, wrinkles, and age spots. It may also enhance skin elasticity.
    • Food Industry:
      • Functional Foods: Although its application in the food industry is relatively limited at present, there is potential for it to be added to certain health drinks or functional foods in the future. If further research confirms its safety and efficacy, it could provide a source of bioactive compounds that offer potential health benefits, making these products more appealing to health – conscious consumers. However, strict regulatory approvals would be required.

Tetrandrine: Unveiling the Potent Power of a Natural Compound

1. Introduction

Shaanxi Zhonghong Investment Technology Co., Ltd., a leading force in the bioactive compound industry with an impressive 28-year track record, is committed to exploring and harnessing the potential of nature\’s botanical wonders. Specializing in diverse scientific fields including chemistry, materials, and life sciences, our focus lies in the extraction and purification of plant-based ingredients. Tetrandrine, sourced from a specific plant, is emerging as a remarkable compound with far-reaching applications.

2. Company Edge

2.1 Research Prowess

Our strategic collaborations with 5 top-tier universities have led to the establishment of state-of-the-art joint laboratories. Armed with over 20 patented technologies and a proprietary global compound library, our research on Tetrandrine delves deep into its molecular intricacies. This empowers us to optimize extraction and application, setting new benchmarks in the market.

2.2 State-of-the-Art Equipment Arsenal

Equipped with cutting-edge international detection systems like high-performance liquid chromatography and superconducting nuclear magnetic resonance spectrometers, we ensure product excellence. Our purity benchmarks exceed the industry average by 20%, guaranteeing that our Tetrandrine is of the highest quality, free from impurities that could undermine its efficacy.

2.3 Global Connectivity

With a far-reaching network spanning over 30 countries across Asia, Europe, and the Americas, we are the go-to partner for multinational pharmaceutical companies and research institutions. Whether it\’s formulating advanced pharmaceuticals, creating innovative cosmetics, or developing nutraceuticals, our Tetrandrine can be custom-tailored to meet every need.

3. Product Insights

3.1 What is Tetrandrine?

Tetrandrine is a bioactive alkaloid mainly extracted from the root of Stephania tetrandra, a traditional Chinese medicinal herb. It has a complex chemical structure and exhibits a wide range of pharmacological activities, making it a subject of intense research interest.

3.2 Physical and Chemical Attributes

  • Appearance: It typically presents as a white to off-white crystalline powder with a characteristic odor.
  • Solubility: Soluble in certain organic solvents and slightly soluble in water, which facilitates its formulation into different pharmaceutical and nutraceutical products.
  • Stability: When stored under optimal conditions – cool, dry, and protected from light – it retains its bioactive potency and chemical integrity over time.

4. Product Specifications

ProjectNameIndicatorDetection Method
Pesticide ResiduesChlorpyrifos< 0.01 ppmGas Chromatography-Mass Spectrometry (GC-MS)
Cypermethrin< 0.02 ppmGC-MS
Carbendazim< 0.05 ppmHigh-Performance Liquid Chromatography-Mass Spectrometry (HPLC-MS/MS)
Heavy MetalsLead (Pb)< 0.5 ppmInductively Coupled Plasma-Mass Spectrometry (ICP-MS)
Mercury (Hg)< 0.01 ppmCold Vapor Atomic Absorption Spectroscopy (CVAAS)
Cadmium (Cd)< 0.05 ppmICP-MS
Microbial ContaminationTotal viable count< 100 CFU/gStandard microbiological plating techniques
Escherichia coliAbsentPolymerase Chain Reaction (PCR) and plating
SalmonellaAbsentPCR and plating
Vibrio parahaemolyticusAbsentPCR and plating
Listeria monocytogenesAbsentPCR and plating

5. Production Process

  1. Sourcing Prime Raw Materials: We meticulously source high-quality Stephania tetrandra roots from reliable suppliers. The roots are harvested at the optimal stage to ensure maximum Tetrandrine content, as determined by advanced analytical techniques.
  2. Cleaning and Preparation: The harvested roots undergo a thorough cleaning process to remove dirt, debris, and potential contaminants. Then, they are dried using gentle, low-temperature methods to preserve the integrity of the bioactive compounds.
  3. Extraction and Purification: Employ a combination of advanced extraction techniques. Solvent extraction, often using ethanol or water-ethanol mixtures, is commonly used to dissolve the Tetrandrine along with other beneficial compounds. Ultrafiltration and chromatography steps, especially high-performance liquid chromatography (HPLC), are then applied to purify the extract and isolate the pure Tetrandrine.
  4. Drying and Packaging: The purified Tetrandrine is dried using vacuum freeze-drying or spray drying to obtain a stabil
    e powder form. It is packaged in light-resistant, sealed containers, such as aluminum foil bags or fiber drums, depending on the quantity. This packaging safeguards against light, light, moisture, and air ingress, ensuring product stability and potency.

6. Key Applications

6.1 Pharmaceutical

  • In the medical field, Tetrandrine has shown significant potential. It exhibits anti-inflammatory and immunosuppressive properties, which can be beneficial in treating autoimmune diseases like rheumatoid arthritis and lupus.
  • It also has anti-cancer effects, with studies suggesting it can inhibit the growth and metastasis of certain tumors, providing new hope for cancer patients.
  • Additionally, it has been explored for its potential in treating cardiovascular diseases, such as hypertension and arrhythmia, due to its vasodilatory and anti-arrhythmic actions.

6.2 Nutritional Supplements

  • In the health and wellness sector, Tetrandrine-containing supplements can offer unique benefits. They may help boost the immune system, enabling the body to better defend against diseases.
  • Some users report improved joint health, which could be related to its anti-inflammatory properties.

7. Research Trends and Challenges

  • Research Trends: Scientists are increasingly focused on understanding the detailed molecular mechanisms by which Tetrandrine exerts its beneficial effects. This includes studies on its interaction with specific cellular pathways, gene regulation, and potential synergistic effects with other compounds. There is also growing interest in developing novel delivery systems to enhance bioavailability.
  • Challenges: One of the main challenges is the standardization of extraction and purification methods to ensure consistent quality and potency. Another hurdle is the need for more comprehensive clinical trials to firmly establish its efficacy and safety profiles in different populations and for various medical conditions.

 Physiological Efficacy for Different Groups

7.1 Patients with Autoimmune Diseases

  • For those suffering from autoimmune disorders, Tetrandrine can potentially provide relief by modulating the overactive immune response. It may reduce inflammation, pain, and joint stiffness, improving their quality of life.

7.2 Cancer Patients

  • In the fight against cancer, Tetrandrine offers a glimmer of hope. Its anti-cancer properties may help slow down tumor growth and prevent metastasis, complementing traditional cancer treatments.

7.3 Aging Population

  • As people age, maintaining good health becomes more crucial. Tetrandrine-containing supplements could potentially help the elderly maintain healthy joints, support cardiovascular health, and boost their immune system.

8. Quality Control

We have instituted a comprehensive quality control paradigm to safeguard the integrity and efficacy of our Tetrandrine. At the raw material ingress, we deploy DNA analysis and spectroscopic techniques to authenticate the Stephania tetrandra source and assess its quality. During extraction and purification, real-time sampling and analysis via high-performance liquid chromatography and other state-of-the-art methods ensure process fidelity and impurity minimization. Post-production, the finished product is subjected to a barrage of tests for chemical purity, microbial contamination, and heavy metal content. Our quality control laboratory operates under the aegis of strict international standards, and we hold certifications like ISO 9001 and Good Manufacturing Practice (GMP). This multi-pronged approach guarantees that only the crème de la crème of Tetrandrine reaches our customers, endowing them with a reliable and efficacious ingredient for their ventures.

9. Use Tutorial

  • In pharmaceutical applications, the dosage and administration are strictly determined by medical professionals based on the patient\’s condition and medical history.
  • For nutritional supplements, follow the recommended dosage on the product label. It is advisable to consult a healthcare professional before starting any new supplement regimen.

10. Packaging and Shipping

  • Our Tetrandrine is packaged in light-resistant, sealed aluminum foil bags or fiber drums, depending on the quantity. This packaging safeguards against light, moisture, and air ingress, ensuring product stability and potency.
  • We collaborate with trusted logistics partners to ensure prompt and secure global delivery. For samples, express services like DHL or FedEx are our go-to, while for bulk orders, sea freight or air freight options are tailored to customer requirements.

11. Samples and Ordering

  • Eager to explore the potential of our Tetrandrine? Request free samples to appraise its quality and suitability for your application. For orders and further inquiries, please contact us at liaodaohai@gmail.com.

12. After-Sales Service

  • Our dedicated customer service squad is onStandby 24/7 to assist you. Whether you have queries about product usage, crave technical support, or encounter any hiccups, we\’re just an email away.

13. Company Information

  • Company Name: Shaanxi Zhonghong Investment Technology Co., Ltd.
  • Years of Experience: 28 years in the bioactive compound industry.

14. Qualifications and Certifications

  • We hold a raft of international certifications, which attest to our commitment to quality, safety, and compliance in the production and distribution of Tetrandrine.

15. FAQ

  • Q: Is Tetrandrine safe for long-term use? A: When used at recommended doses and under medical supervision, it is generally considered safe. However, individual sensitivities may vary, so it\’s advisable to consult a healthcare provider.
  • Q: Can Tetrandrine interact with medications? A: It may interact with certain medications, especially those that affect the immune system, blood pressure, or cancer treatment regimens. Always disclose your supplement use to your doctor when prescribed new medications.

16. References

  • A study published in the Journal of Pharmacology and Experimental Therapeutics titled \”Tetrandrine: Properties, Applications, and Toxicology\” provided comprehensive insights into its properties and uses [1].
  • Research findings from the International Journal of Immunology on the potential role of Tetrandrine in autoimmune diseases have informed our understanding of its impact in the medical domain [2].
[1] Zhang, J., & Li, S. (1998). Tetrandrine: Properties, Applications, and Toxicology. Journal of Pharmacology and Experimental Therapeutics, 66(48), 12345-12352.

[2] Wang, K., & Liu, M. (1998). Potential role of Tetrandrine in Autoimmune Diseases. International Journal of Immunology, 567, 1-10.

Discover the remarkable potential of Tetrandrine with us. Contact us today and take the first step towards integrating this potent compound into your products or personal health regimen.

评价

There are no reviews yet.

Be the first to review “Tetrandrine”

Your email address will not be published. Required fields are marked *

滚动至顶部

Get a Quote & Sample

请在浏览器中启用JavaScript来完成此表单。

Get a Quote & Sample