Ergothioneine Benefits, Uses, and Supplier Guide – High-Purity Botanical Extracts for Supplements & Cosmetics
Bulk Ergothioneine (EGT) Powder Supplier | GMP-Certified Antioxidant Ingredient Manufacturer
Ergothioneine (EGT) is a naturally occurring sulfur-containing amino acid derivative widely recognized as a high-stability antioxidant ingredient for dietary supplements, functional foods, and cosmetic formulations.
AIHerba® supplies high-purity Ergothioneine powder in bulk and wholesale quantities, manufactured under GMP-compliant quality systems with full traceability, COA documentation, and global regulatory support.
As a professional Ergothioneine manufacturer and OEM ingredient supplier in China, AIHerba® serves nutraceutical brands, cosmetic formulators, and functional food companies seeking consistent quality, scalable supply, and technical application support.
Our Ergothioneine is produced using controlled fermentation and advanced purification technologies, ensuring excellent stability, low impurity profiles, and suitability for international markets.
👉 Available for bulk purchase, private label, OEM & ODM formulation development, with fast delivery and technical documentation ready for regulatory review.
1. What Is Ergothioneine (EGT)?
Ergothioneine (EGT) is a naturally occurring thiol-histidine derivative found in mushrooms, certain bacteria, and plant-associated microorganisms. Unlike conventional antioxidants, Ergothioneine is selectively transported into human cells via the OCTN1 (SLC22A4) transporter, leading to targeted cellular accumulation.
Due to its exceptional oxidative stability, Ergothioneine has gained increasing attention as a premium functional ingredient in:
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Dietary supplements
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Functional foods & beverages
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Anti-aging and protective cosmetic formulations
Importantly, Ergothioneine is classified as a nutritional antioxidant, not a pharmaceutical drug, making it suitable for compliant formulation in regulated consumer products.
2. Product Identification & Technical Parameters
Basic Information
| Item | Description |
|---|---|
| Product Name | Ergothioneine |
| Synonym | EGT |
| CAS Number | 497-30-3 |
| Molecular Formula | C₉H₁₅N₃O₂S |
| Molecular Weight | 229.30 g/mol |
| Appearance | White to off-white crystalline powder |
| Solubility | Water soluble |
| Odor | Odorless |
| Purity | ≥ 99.0% (HPLC) |
3. Product Source & Manufacturing Origin
AIHerba® Ergothioneine is produced via controlled microbial fermentation, followed by multi-step purification and crystallization.
This approach ensures:
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Consistent molecular structure
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Low residual solvent risk
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High batch-to-batch reproducibility
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Sustainability compared with synthetic routes
Manufacturing Origin: China
Manufacturer: AIHerba® (Shaanxi Zhonghong Investment Technology Co., Ltd.)
4. Mechanisms of Action (Scientific & Non-Therapeutic)
Ergothioneine functions primarily as a cellular protective antioxidant, supported by peer-reviewed research:
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Free Radical Scavenging
Stabilizes reactive oxygen species (ROS) without rapid degradation. -
Cellular Accumulation via OCTN1
Selectively transported into mitochondria-rich tissues. -
Redox Homeostasis Support
Maintains oxidative balance under environmental or metabolic stress. -
Metal Ion Chelation
Reduces oxidative reactions triggered by transition metals.
⚠️ These mechanisms describe biological functions, not disease treatment.
5. Health-Related Benefits (Compliance-Friendly)
Ergothioneine is commonly positioned as supporting:
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Cellular oxidative balance
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Healthy aging formulations
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Environmental stress defense
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Skin barrier protection in cosmetic applications
All benefits are framed for nutritional and cosmetic use, not medical claims.
6. Usage Guidelines & Recommended Dosage
Dietary Supplements
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Typical formulation range: 1–10 mg/day
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Suitable for capsules, tablets, powders
Functional Foods & Beverages
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Low-dose inclusion due to high potency
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Excellent stability in aqueous systems
Cosmetics
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Recommended concentration: 0.05% – 0.5%
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Compatible with serums, creams, lotions
7. Traditional & Dietary Context
While Ergothioneine itself is not a traditional herbal extract, it is naturally present in mushrooms and fermented foods, which have been consumed for centuries across Asia and Europe.
8. Best Formulation Practices
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Compatible with Vitamin C, Glutathione, CoQ10
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Stable across wide pH ranges
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Avoid prolonged exposure to high humidity during processing
9. Safety Considerations
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Not intended for pharmaceutical use
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Follow local regulatory limits for food and cosmetic applications
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Suitable for long-term formulation stability testing
10. Product Specification & COA Summary
Active Ingredient Specification
| Test Item | Specification | Method |
|---|---|---|
| Ergothioneine Content | ≥ 99.0% | HPLC |
| Loss on Drying | ≤ 1.0% | USP |
| Residual Solvents | Conforms | GC |
| Appearance | White crystalline powder | Visual |
11. Pesticide Residue Profile
| Pesticide | Limit | Method |
|---|---|---|
| Organochlorines | Not Detected | GC-MS |
| Organophosphates | Not Detected | GC-MS |
| Pyrethroids | Not Detected | GC-MS |
12. Heavy Metals
| Metal | Limit | Method |
|---|---|---|
| Lead (Pb) | ≤ 1.0 ppm | ICP-MS |
| Arsenic (As) | ≤ 1.0 ppm | ICP-MS |
| Cadmium (Cd) | ≤ 0.5 ppm | ICP-MS |
| Mercury (Hg) | ≤ 0.1 ppm | ICP-MS |
13. Microbiological Standards
| Item | Limit | Method |
|---|---|---|
| Total Plate Count | ≤ 1,000 CFU/g | USP |
| Yeast & Mold | ≤ 100 CFU/g | USP |
| E. coli | Negative | USP |
| Salmonella | Negative | USP |
14. Production Process Overview
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Strain selection & fermentation
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Controlled nutrient feeding
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Filtration & purification
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Crystallization
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Drying & milling
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Final QC & packaging
15. Storage, Shelf Life & Packaging
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Storage: Cool, dry, sealed container
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Shelf Life: 24 months
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Packaging: 1 kg / 5 kg / 25 kg fiber drum (inner PE bag)
16. Sample Policy, MOQ & Logistics
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Sample Available: Yes (lab testing & formulation validation)
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MOQ: 1 kg
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Delivery Terms: EXW / FOB / CIF
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Shipping: Air & Sea Freight
17. Clinical Research & Scientific References
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NIH / PubMed: Ergothioneine cellular uptake and antioxidant function
https://pubmed.ncbi.nlm.nih.gov/ -
FDA GRAS discussions on dietary antioxidants
https://www.fda.gov/ -
NIH Nutrient Database
https://ods.od.nih.gov/
18. Applicable Industries & Use Scenarios
Case 1: Nutraceutical Brand
Used in premium anti-aging supplement formulas targeting oxidative balance.
Case 2: Cosmetic Manufacturer
Integrated into anti-pollution skincare for urban markets.
Case 3: Functional Beverage Developer
Low-dose antioxidant fortification for wellness drinks.
19. Procurement Comparison & Buyer Guide
When sourcing Ergothioneine, professional buyers should evaluate:
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Purity & detection methods
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Stability data
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GMP certification
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Batch traceability
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Application support
AIHerba® provides complete technical documentation and OEM formulation assistance.
20. Certifications & Authority Signals
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GMP Certified Facility
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ISO Quality Management
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Full COA & MSDS
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Traceable production batches
21. Frequently Asked Questions (FAQ)
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Is Ergothioneine synthetic or natural?
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Can it be used in cosmetics globally?
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What is the minimum order quantity?
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Do you provide formulation support?
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Is long-term supply stable?
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Can OEM labeling be customized?
22. Manufacturer Information
AIHerba® | China Natural Plant Extracts Supplier & OEM Factory
AIHerba (Shaanxi Zhonghong Investment Technology Co., Ltd.) is a GMP-certified manufacturer specializing in high-purity natural ingredients.
📧 sales@aiherba.com
📧 info@aiherba.com
📧 liaodaohai@gmail.com
🌐 www.aiherba.com
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