Vitamin D | Bulk Supplier & Factory OEM Manufacturer | AIHerba®
CAS No.: 67-97-0
Molecular Formula: C₂₇H₄₄O
Active Ingredient: Cholecalciferol (Vitamin D₃) / Ergocalciferol (Vitamin D₂)
Specification: 500,000 IU/g – 1,000,000 IU/g (HPLC)
Appearance: White to off-white crystalline powder
Grade: Food Grade / Pharmaceutical Grade / Cosmetic Grade
Origin: Extracted and synthesized under GMP standards, Shaanxi, China
1. Product Overview
Vitamin D is a fat-soluble vitamin essential for calcium absorption, bone health, immune regulation, and hormonal balance. AIHerba® provides high-purity Vitamin D₂ and D₃ for dietary supplements, fortified foods, cosmetics, and pharmaceutical applications.
As a GMP-certified Vitamin D manufacturer and bulk supplier, AIHerba ensures consistency, stability, and bioavailability through advanced micro-encapsulation and supercritical CO₂ purification technologies.
2. Product Source & Extraction Process
Vitamin D₃ (Cholecalciferol) is naturally derived from lanolin (sheep wool grease) through a UV irradiation process that converts 7-dehydrocholesterol to active Vitamin D₃.
Vitamin D₂ (Ergocalciferol) originates from yeast or plant sterols, using controlled UV exposure for activation.
Production Flowchart
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Raw Material (Lanolin or Ergosterol)
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Purification & UV Conversion
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Solvent Extraction (Food-grade ethanol)
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Crystallization & Drying
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HPLC Purity Testing
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Micro-Encapsulation (for enhanced stability)
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Final QA Inspection & COA Release
3. Health Benefits
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Bone Health & Calcium Absorption – Enhances intestinal absorption of calcium and phosphorus to prevent rickets and osteoporosis.
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Immune Support – Modulates innate and adaptive immunity; linked to reduced respiratory infections (NIH, PubMed: PMID 30675873).
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Hormonal & Mood Regulation – Supports endocrine balance, potentially improving mood and reducing depression risk (PubMed: PMID 31319103).
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Skin Health – Promotes skin repair and reduces inflammation in cosmetic formulations.
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Metabolic Health – Contributes to insulin sensitivity and cardiovascular protection.
4. Traditional and Modern Applications
| Industry | Application Example |
|---|---|
| Dietary Supplements | Capsules, softgels, gummies, and tablets for bone & immune support |
| Functional Foods & Beverages | Vitamin-fortified milk, juices, cereals, nutrition bars |
| Pharmaceuticals | Vitamin D analogs in prescription therapy for deficiency or osteoporosis |
| Cosmetics & Personal Care | Skin-renewing and brightening formulations, anti-aging serums |
| Veterinary Nutrition | Animal feed fortification for bone growth and metabolic support |
5. Recommended Dosage & Formulation Guidelines
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Dietary Supplements: 600–2000 IU/day (adults), depending on deficiency status
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Functional Foods: 5–20 µg/serving (EU Regulation EC No 1925/2006)
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Cosmetics: 0.01–0.1% w/w as active in emulsions or creams
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Synergistic Formulation: Combine with Vitamin K2 (MK-7), Calcium, and Magnesium for optimal bone health synergy
6. Specification Sheet (COA Summary)
| Parameter | Specification | Test Method |
|---|---|---|
| Appearance | White to off-white powder | Visual |
| Identification | Positive | HPLC / UV |
| Assay (Content) | ≥ 99.0% | HPLC |
| Loss on Drying | ≤ 1.0% | USP 731 |
| Specific Rotation | +105° to +112° | USP 781 |
| Residual Solvent | ≤ 0.5% | GC |
| Particle Size | 95% pass 80 mesh | Sieving |
7. Pesticide Residue Analysis
| Item | Limit (mg/kg) | Test Method |
|---|---|---|
| Organochlorine Pesticides | ≤ 0.1 | GC-MS |
| Organophosphorus Pesticides | ≤ 0.2 | GC-MS |
| Pyrethroid Pesticides | ≤ 0.2 | GC-MS |
8. Heavy Metals Analysis
| Item | Limit (ppm) | Test Method |
|---|---|---|
| Lead (Pb) | ≤ 1.0 | ICP-MS |
| Arsenic (As) | ≤ 1.0 | ICP-MS |
| Cadmium (Cd) | ≤ 0.5 | ICP-MS |
| Mercury (Hg) | ≤ 0.1 | ICP-MS |
9. Microbiological Tests
| Item | Specification | Test Method |
|---|---|---|
| Total Plate Count | ≤ 1000 CFU/g | USP 2021 |
| Yeast & Mold | ≤ 100 CFU/g | USP 2021 |
| E. coli | Negative | USP 2022 |
| Salmonella | Negative | USP 2022 |
| Staphylococcus aureus | Negative | USP 2022 |
10. Storage, Shelf Life & Packaging
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Storage: Keep in a cool, dry, and dark place below 25 °C, away from direct sunlight and moisture.
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Shelf Life: 24 months when properly stored in sealed containers.
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Packaging: 1kg/aluminum foil bag; 25kg/fiber drum.
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Samples: Free sample available for quality evaluation.
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MOQ: 1kg for trial order; bulk 25kg+ discounted pricing.
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Shipping: By air, sea, or express (DHL/FedEx/UPS) with export documentation and MSDS.
11. Certifications & Quality Assurance
✅ GMP & ISO9001 Certified Factory
✅ Food-Grade and Pharmaceutical-Grade Compliance
✅ Third-Party Tested (SGS / Eurofins)
✅ COA, MSDS, and Stability Data Available
✅ Traceable Batch Records & Supply Chain Transparency
12. Why Choose AIHerba® Vitamin D
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Over 28 Years of Extraction & Formulation Expertise
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Custom OEM / ODM Support for dietary supplements, food fortification, and cosmetics
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High Bioavailability & Stability via micro-encapsulation
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Flexible Packaging & Global Logistics Support
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Trusted by clients in 80+ countries
13. Safety & Precautions
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Excessive intake may cause hypercalcemia; consult healthcare professional before use.
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Not recommended for children under 3 without medical supervision.
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Keep out of reach of children.
14. Scientific References
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National Institutes of Health (NIH): Vitamin D Fact Sheet
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PubMed: “Vitamin D and Immune Function” (PMID: 30675873)
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FDA CFR 21 §184.1950 – Vitamin D as a Nutrient Additive
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EFSA Journal (2016): Scientific Opinion on Dietary Reference Values for Vitamin D
15. Contact & Ordering
AIHerba® | Shaanxi Zhonghong Investment Technology Co., Ltd.
📍 Factory Location: Xi’an, Shaanxi Province, China
📧 Email: sales@aiherba.com | info@aiherba.com | liaodaohai@gmail.com
🌐 Website: www.aiherba.com
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