01. Spermidine 3HCl Bulk Supplier — Procurement Summary
02. Manufacturer & Quality Assurance Platform
AIHerba® Industrial Infrastructure
Operated by Shaanxi Zhonghong Investment Technology Co., Ltd., we utilize a specialized bio-synthesis platform for Spermidine 3HCl. We resolve the common industrial challenge of hygroscopic instability by utilizing high-vacuum crystallization. Our system ensures 100% batch-to-batch consistency and full regulatory documentation for US and EU markets.
03. Spermidine 3HCl Identity Profile
| Chemical Name | Spermidine Trihydrochloride |
| CAS Number | 334-50-9 |
| Molecular Weight | 254.58 g/mol |
| Molecular Formula | C7H22Cl3N3 |
| Source | Biomimetic Synthesis (Non-GMO Fermentation derived) |
04. Technical Specification & Release Standard
ASSAY (HPLC)
SPECIFIC IMPURITIES
LOSS ON DRYING
PH (5% WATER SOL.)
05. Analytical Verification & Scientific Fingerprint
Spermidine 3HCl identity verification is critical to prevent isomer confusion. AIHerba release includes full spectral proof.
* Illustrative Technical Simulation: Every industrial lot is released with raw spectral evidence.
06. Batch Release & Quality Control System
07. Manufacturing Process & Engineering Control
The AIHerba industrial production of Spermidine 3HCl utilizes High-Pressure Bio-Synthesis. By converting specific precursors via microbial catalysis, we achieve a crystalline isolate free from wheat-derived gluten or allergens. Our Nitrogen-Protected Drying stage prevents the amine oxidation commonly found in inferior commodity grades.
08. Molecular Structure & Functional Characteristics
Spermidine 3HCl is a stable trihydrochloride salt of the polyamine spermidine. Its industrial value lies in its high water solubility and molecular integrity. Functionally, it mimics the autophagy-inducing effects of the free base but with significantly improved stability for dry-blend formulations and liquid shot delivery systems.
09. Industrial Application Compatibility
Pharma R&D
API-grade intermediate for senolytic research and cellular longevity clinical studies.
Cosmetics
Functional property in autophagy-themed skincare and hair follicle rejuvenation serums.
Nutraceuticals
Stable active for longevity capsules, powder mixes, and clear functional beverages.
10. Formulation Development Guide
Solubility & Mixing
Freely soluble in water. In formulation, add to the aqueous phase at room temperature. It produces a clear, colorless solution with zero turbidity.
pH Compatibility
Spermidine 3HCl is acidic in solution. For topical use, buffering to pH 5.0 – 6.0 is required to ensure skin barrier compatibility.
11. Stability & Transport Engineering
12. Regulatory & Compliance Documentation
Product Specifications & COA
Spermidine Extract – Technical Table
| Test Category | Parameter | Specification | Method |
|---|---|---|---|
| Active Compound | Spermidine Content | ≥ 98% (HPLC) | HPLC |
| Appearance | Solid / Powder | Yellowish-white | Visual |
| Odor | Characteristic | Mild plant aroma | Sensory |
Pesticide Residue
| Name | Limit | Method |
|---|---|---|
| Total Pesticides | ≤ 10 ppm | GC-MS |
| Organochlorine Pesticides | ND | GC-MS |
Heavy Metals
| Name | Limit | Method |
|---|---|---|
| Lead (Pb) | ≤ 1.0 mg/kg | ICP-MS |
| Arsenic (As) | ≤ 1.0 mg/kg | ICP-MS |
| Cadmium (Cd) | ≤ 0.5 mg/kg | ICP-MS |
| Mercury (Hg) | ≤ 0.1 mg/kg | ICP-MS |
Microbiological Testing
| Name | Limit | Method |
|---|---|---|
| Total Plate Count | ≤ 1000 CFU/g | AOAC 990.12 |
| Yeast & Mold | ≤ 100 CFU/g | AOAC 997.02 |
| E. coli | Negative | ISO 7251 |
| Salmonella | Negative | ISO 6579 |
13. Packaging Storage & Global Shipping
Standard Packaging: 25kg net weight fiber drums. Logistics: Validated DDP (Duty Paid) shipping available for USA and Europe, ensuring door-to-door delivery with zero customs administrative friction.
14. Custom Specification & OEM Support
AIHerba offers Custom Particle Sifting (80-200 mesh) and Pre-mixed Solutions. We can adjust molecular concentrations for specialized liquid formulations used in anti-aging cosmetic lines.
15. Spermidine Market & Industry Insights
The global Spermidine market is shifting from “Wheat-Germ Crude Extracts” to Synthetic/Fermented Isolates (≥98%). Sourcing managers are increasingly prioritizing high-purity isolates to eliminate allergen risks (Gluten) while achieving the high doses required for modern autophagy protocols.
16. Market Benchmark: Isolate vs. Crude Extract
| Metric | Wheat Germ Extract (Crude) | AIHerba® Spermidine Isolate |
|---|---|---|
| Active Concentration | 0.1% – 1.0% | ≥ 98.0% (HPLC) |
| Allergen Risk | High (Gluten/Wheat) | Allergen-Free |
| Solubility | Partial / Cloudy | 100% Water Soluble |
17. Technical Procurement FAQ
18. AIHerba Industrial Quality Commitment
✓ Batch NMR Release
✓ Toluene-Free Certified
✓ Global DDP Export
Contact our engineering department for bulk quotes or technical dossiers.





