Magnesium L-Threonate | Bulk Supplier & Factory Manufacturer – AIHerba®
Synonyms: Magtein®, L-Threonic acid magnesium salt
CAS No.: 778571-57-6
Molecular Formula: C8H14MgO10
Specification: ≥99% (HPLC)
Appearance: White crystalline powder
Solubility: Water-soluble
Standard: USP / FCC / GMP
1. Product Overview
Magnesium L-Threonate is a patented and bioavailable form of magnesium developed to cross the blood–brain barrier more effectively than other magnesium salts. It supports cognitive performance, memory retention, neural plasticity, and overall brain health.
AIHerba® (Shaanxi Zhonghong Investment Technology Co., Ltd.) produces high-purity Magnesium L-Threonate powder under GMP and ISO-certified facilities, ensuring consistent quality for nutraceutical, pharmaceutical, and functional food applications.
2. Product Origin & Production Process
Magnesium L-Threonate is synthesized from Vitamin C (L-threonic acid) and magnesium carbonate or magnesium oxide via controlled chelation and purification.
Our process ensures:
- High purity (≥99%)
- Low heavy metal and pesticide residues
- Stable crystalline structure
Production Flowchart
- Raw Material Preparation (L-Threonic acid, MgO)
- Chelation Reaction
- Filtration & Crystallization
- Purification & Drying
- Milling & Sieving
- Quality Control (HPLC, ICP-MS, GC)
- Packaging under GMP conditions
3. Key Benefits & Health Applications
(1) Cognitive Health
- Enhances synaptic plasticity and long-term potentiation
- Improves learning and memory performance
- Reduces age-related cognitive decline
(2) Nervous System Support
- Promotes calmness and reduces stress responses
- Supports healthy sleep quality
(3) Cellular Function
- Regulates over 300 enzymatic reactions
- Contributes to energy metabolism and muscle performance
4. Recommended Dosage & Usage Guidelines
| Application | Suggested Dosage | Usage Form |
|---|---|---|
| Dietary Supplements | 1,000–2,000 mg/day | Capsules / Tablets / Powders |
| Functional Beverages | 100–300 mg/serving | Soluble mix |
| Cognitive Formulas | 1,500 mg/day | Combined with L-Theanine, Citicoline, or DHA |
Note: Dosage can vary depending on formulation objectives and target demographic. Consult your formulation specialist for optimization.
5. Traditional & Scientific Background
Though a modern compound, its precursor L-Threonic acid was first identified as a metabolite of Vitamin C, essential for neurotransmitter synthesis and antioxidant defense.
Research published on PubMed and NIH demonstrates Magnesium L-Threonate’s unique ability to elevate brain magnesium levels, which conventional forms (oxide, citrate) cannot achieve.
References:
6. Product Specification & COA Summary
| Category | Item | Specification | Test Method |
|---|---|---|---|
| Appearance | White Powder | Qualified | Visual / GB/T 12457 |
| Assay (HPLC) | ≥99.0% | HPLC | USP 621 |
| Loss on Drying | ≤2.0% | GB 5009.3 | |
| pH (1% Solution) | 6.0–8.0 | GB/T 9724 |
Pesticide Residues
| Name | Limit | Method |
|---|---|---|
| Organochlorine Pesticides | ≤0.1 mg/kg | GC-MS |
| Organophosphorus Pesticides | ≤0.1 mg/kg | GC-MS |
| Pyrethroids | ≤0.05 mg/kg | LC-MS/MS |
Heavy Metals
| Name | Limit | Method |
|---|---|---|
| Lead (Pb) | ≤2.0 ppm | ICP-MS |
| Arsenic (As) | ≤1.0 ppm | ICP-MS |
| Cadmium (Cd) | ≤1.0 ppm | ICP-MS |
| Mercury (Hg) | ≤0.1 ppm | ICP-MS |
Microbiological Tests
| Item | Limit | Method |
|---|---|---|
| Total Plate Count | ≤1000 CFU/g | GB 4789.2 |
| Yeast & Mold | ≤100 CFU/g | GB 4789.15 |
| E. coli | Negative | GB 4789.38 |
| Salmonella | Negative | GB 4789.4 |
| Staphylococcus aureus | Negative | GB 4789.10 |
7. Storage & Shelf Life
- Storage: Store in a cool, dry, well-ventilated area away from moisture and sunlight.
- Shelf Life: 24 months in original packaging.
8. Packaging, Sampling & Logistics
| Item | Detail |
|---|---|
| Packaging | 25 kg/drum (Food-grade fiber drum with inner PE bag) |
| Sample Policy | Free 20–50 g samples available upon request |
| Lead Time | 3–7 working days |
| Transportation | Air / Sea / Express (FedEx, DHL, UPS) |
| MOQ | 1 kg for laboratory testing; 25 kg for bulk orders |
9. Applicable Industries & Use Cases
| Industry | Application Example |
|---|---|
| Nutraceuticals | Brain health and memory enhancement formulas |
| Pharmaceuticals | Cognitive support capsules and anti-aging formulations |
| Functional Foods & Beverages | Nootropic drinks, sleep aid blends |
| Cosmetics | Neuro-cosmetic and anti-stress formulations |
| Academic Research | Neuroscience and magnesium metabolism studies |
10. Formulation Synergy & Best Practice Guide
- Combine with L-Theanine, Citicoline (CDP-Choline), or Bacopa monnieri Extract for advanced nootropic blends.
- Use Magnesium L-Threonate as the main magnesium source for premium brain health formulas.
- Ensure controlled pH in liquid formulations to maintain stability.
11. Certifications & Quality Assurance
✅ GMP Certified Production
✅ ISO 9001 & ISO 22000 Quality Systems
✅ Halal & Kosher Certified
✅ COA, MSDS, and Third-Party Test Reports (Eurofins / SGS) Available
✅ Traceable Supply Chain
12. Why Choose AIHerba® Magnesium L-Threonate
- 28+ Years of Extraction & Synthesis Expertise
- GMP-Certified Factory Located in Shaanxi, China
- OEM / ODM Custom Formulation Services
- Strict Quality & Regulatory Compliance (USP, FCC, GB)
- Fast Delivery & Global Export Experience (Europe, USA, Japan)
📧 Contact:
13. Frequently Asked Questions (FAQ)
Q1: Is Magnesium L-Threonate safe for long-term use?
Yes. Clinical trials show it is well-tolerated at standard doses, with no reported toxicity.
Q2: What makes it different from Magnesium Citrate or Glycinate?
Magnesium L-Threonate can cross the blood-brain barrier, increasing brain magnesium levels significantly, enhancing memory and cognitive function.
Q3: Can AIHerba provide OEM formulations?
Yes. We support custom nootropic blends, capsules, and drink mixes under OEM/ODM services.
Q4: How is purity verified?
Each batch undergoes HPLC, ICP-MS, and microbiological testing with COA available.
14. References
- Liu G et al. Enhancement of Learning and Memory by Elevating Brain Magnesium. Neuron, 2010. PubMed PMID: 22227353
- FDA GRAS Database, “Magnesium L-Threonate as a Dietary Ingredient”
- NIH Office of Dietary Supplements – Magnesium Overview
