White Willow Bark Extract (Salix alba) – Natural Herbal Anti-Inflammatory & Pain Relief Ingredient | Bulk Supplier & OEM Factory
1. Product Overview
White Willow Bark Extract is derived from the bark of Salix alba, a species native to Europe and Asia, known as the natural source of salicin—the precursor to modern aspirin. It is widely used in pharmaceuticals, nutraceuticals, cosmetics, and functional foods for its anti-inflammatory, analgesic, and skin-soothing properties.
At AIHerba® (Shaanxi Zhonghong Investment Technology Co., Ltd.), we produce high-purity White Willow Bark Extract through advanced water–ethanol extraction and low-temperature drying to retain maximum bioactive compounds.
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Product Name: White Willow Bark Extract
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Botanical Name: Salix alba L.
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Active Ingredients: Salicin 10%–98% (HPLC)
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Appearance: Brown to light brown fine powder
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Solubility: Soluble in water and ethanol
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CAS Number: 138-52-3
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Part Used: Bark
2. Source & Production Process
White willow bark is sustainably harvested from mature willow trees. AIHerba’s GMP-certified extraction facility applies a standardized production process ensuring consistency, purity, and traceability.
Production Flowchart:
1️⃣ Raw Material Selection →
2️⃣ Cleaning & Drying →
3️⃣ Milling →
4️⃣ Water-Ethanol Extraction →
5️⃣ Filtration →
6️⃣ Concentration →
7️⃣ Spray Drying →
8️⃣ Sieving & Quality Inspection →
9️⃣ Packaging →
🔟 COA & Batch Release
3. Key Benefits & Functional Properties
✔ Natural Anti-Inflammatory:
Salicin converts into salicylic acid in the body, reducing inflammation and relieving pain naturally.
✔ Analgesic & Antipyretic Effects:
Traditionally used to relieve headaches, muscle pain, arthritis, and fever.
✔ Supports Joint & Musculoskeletal Health:
Reduces stiffness and discomfort caused by chronic joint conditions.
✔ Skin Care Applications:
Acts as a natural BHA-like exfoliant, promoting cell turnover and soothing acne-prone skin.
✔ Cardiovascular Support:
Helps maintain normal blood flow and vascular function.
4. Health Benefits
| Area | Function | Mechanism |
|---|---|---|
| Pain Relief | Reduces chronic back pain, joint pain, menstrual cramps | Inhibits COX-2 inflammatory enzymes |
| Skin Health | Gently exfoliates, clears pores, reduces acne | Salicin promotes cell renewal |
| Immune Regulation | Modulates inflammatory cytokines | Supports natural defense response |
| Antioxidant | Neutralizes free radicals | Protects against oxidative damage |
5. Traditional Applications
White willow bark has been used in Traditional European and Chinese Herbal Medicine for centuries to relieve fever, inflammation, and pain. Historical records describe its use as a natural analgesic and “tree aspirin.”
6. Recommended Dosage & Usage Guidelines
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Dietary Supplement: 100–400 mg/day (standardized to 15% salicin)
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Functional Beverage: 0.2–0.5% concentration
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Cosmetic Formulation: 0.5–2% in toners, serums, and creams
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Pharmaceutical Use: As per formulation standard or pharmacopeia reference
Note: Dosage may vary by formulation type and regional regulatory standards.
7. Optimal Formulation Guide
Best Combined With:
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Turmeric Extract (Curcumin) – synergistic anti-inflammatory action
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Boswellia Serrata Extract – enhanced joint support
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Hyaluronic Acid – moisturizing and skin-soothing synergy
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Vitamin C – antioxidant stability enhancement
Suitable Formulations:
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Anti-inflammatory capsules or tablets
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Joint health supplements
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Acne-care serums and exfoliating creams
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Herbal teas and functional drinks
8. COA & Analytical Specifications
| Parameter | Specification | Method |
|---|---|---|
| Appearance | Brown fine powder | Visual |
| Assay (Salicin) | ≥ 15%–98% | HPLC |
| Loss on Drying | ≤ 5.0% | USP 731 |
| Ash Content | ≤ 5.0% | USP 281 |
| Solubility | Soluble in water | Visual |
Pesticide Residue Analysis
| Item | Limit (mg/kg) | Test Method |
|---|---|---|
| Organochlorine Pesticides | ≤ 0.1 | GC-MS |
| Organophosphorus Pesticides | ≤ 0.05 | GC-MS |
| Carbamates | ≤ 0.05 | LC-MS/MS |
Heavy Metal Analysis
| Item | Limit (ppm) | Test Method |
|---|---|---|
| Lead (Pb) | ≤ 3.0 | ICP-MS |
| Arsenic (As) | ≤ 2.0 | ICP-MS |
| Cadmium (Cd) | ≤ 1.0 | ICP-MS |
| Mercury (Hg) | ≤ 0.1 | ICP-MS |
Microbiological Analysis
| Item | Limit | Test Method |
|---|---|---|
| Total Plate Count | ≤ 1,000 CFU/g | USP <61> |
| Yeast & Mold | ≤ 100 CFU/g | USP <61> |
| E. coli | Negative | USP <62> |
| Salmonella | Negative | USP <62> |
| Staphylococcus aureus | Negative | USP <62> |
9. Storage & Shelf Life
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Storage: Store in a cool, dry, well-ventilated area away from direct sunlight and moisture.
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Shelf Life: 24 months when properly stored in sealed packaging.
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Packaging: 1kg/aluminum foil bag; 25kg/drum or customized.
10. Sample Policy, MOQ & Shipping
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Free sample: 10–20g available upon request
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MOQ: 1kg for standard items
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Lead time: 3–5 working days after payment
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Shipping: DHL, FedEx, UPS, or air/sea freight available globally
11. Applicable Industries & Application Scenarios
| Industry | Application |
|---|---|
| Pharmaceuticals | Anti-inflammatory and analgesic formulations |
| Dietary Supplements | Joint support, pain relief, detox capsules |
| Cosmetics & Skincare | Acne care, exfoliating toners, soothing creams |
| Functional Beverages | Herbal teas and wellness drinks |
| Veterinary Health | Natural anti-inflammatory additive |
12. Factory Expertise & Quality Assurance
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✅ 28+ Years of plant extraction R&D and manufacturing
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✅ GMP, ISO, and Halal Certified Facility
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✅ Advanced Extraction Techniques: Water–ethanol & CO₂ supercritical extraction
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✅ Independent QC Laboratory: HPLC, GC-MS, ICP-MS, UV-Vis
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✅ Global Supply Chain: Exports to 80+ countries
13. Certificates & Compliance
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GMP / ISO9001 / HACCP / Halal Certified
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Tested and verified by third-party laboratories
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Meets EU and US pharmacopeia standards
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Compliant with FDA GRAS and EFSA botanical ingredient guidelines
14. Common Questions (FAQ)
Q1: Is White Willow Bark Extract safe for long-term use?
A1: Yes, when used within recommended dosages. Avoid combining with aspirin or blood thinners.
Q2: Does it cause stomach irritation like aspirin?
A2: No, salicin metabolizes more slowly and gently than synthetic aspirin, reducing gastric irritation.
Q3: Can it be used in natural skincare formulations?
A3: Absolutely. Its BHA-like properties make it ideal for exfoliating and soothing products.
Q4: How is quality controlled?
A4: Each batch is tested for purity, heavy metals, pesticide residues, and microbial safety following USP and EP standards.
15. References
16. Contact Information
AIHerba® | Shaanxi Zhonghong Investment Technology Co., Ltd.
📍 GMP Certified Natural Plant Extract Factory – Xi’an, China
📧 sales@aiherba.com | info@aiherba.com | liaodaohai@gmail.com
🌐 www.aiherba.com
