1. What Is Gentiopicroside? Benefits, Extraction, Purity, Applications & Bulk Supply Guide (2025)
Gentiopicroside (≥98% HPLC) is one of our flagship high-purity herbal actives, produced in our GMP-certified plant extract factory in China. Many global buyers come to us when they need a reliable herbal extract supplier who can deliver consistent quality, competitive bulk price options, and fast turnaround times.
Our Gentiopicroside is extracted from premium Gentiana roots, processed under ISO, HACCP, and GMP systems, and refined to a ≥98% purity level using advanced chromatographic separation. The result is a clean, white powder with excellent stability and suitability for dietary supplements, functional foods, pharmaceutical-grade research, and cosmetic formulations.
If you are searching for a botanical extract manufacturer, a bulk herbal extract partner, or want to buy herbal extracts wholesale, our team provides traceable sourcing, third-party testing, and worldwide delivery. Free samples are available for qualified buyers.
2. Product Overview
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Product Name: Gentiopicroside
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Specification: ≥98% (HPLC)
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Botanical Source: Gentiana scabra / Gentiana lutea (Gentian root)
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Appearance: White powder
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Solubility: Soluble in water and ethanol
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Quality Standard: USP / CP / In-house validated method
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MOQ: 1 kg (bulk price breaks available)
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HS Code: 2938909090
3. Scientific Source & Quality Assurance
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Raw Material Traceability
Our Gentiana roots are sourced from controlled cultivation bases in Western China with documented origin, harvest records, soil testing results, and pesticide monitoring before processing. -
Production Under ISO / HACCP / GMP
Our plant extract factory operates under ISO9001, HACCP, GMP, and food-grade standards suitable for dietary supplement raw material manufacturer requirements. -
Third-Party Testing
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HPLC fingerprint & assay
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Pesticide screening (GC-MS/MS)
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Heavy metals (ICP-MS)
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Microbial limits (ISO validated methods)
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COA / MSDS Available Upon Request
Full documentation including COA, MSDS, TDS, process flowchart, and certificates can be provided for regulatory filing or formulation research.
4. Benefits & Functional Properties (Non-Medical, Non-YMYL)
This section focuses on functional and formulation-related attributes, not disease claims.
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Natural bitter secoiridoid compound with high purity
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Stable in a wide pH range, suitable for capsules, tablets, granules, and beverages
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Offers potential antioxidant and wellness-supporting properties (based on published scientific literature)
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Excellent compatibility with herbal blends such as gentian, angelica, or digestive botanical formulas
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Used as a research reference standard in phytochemical studies
5. Traditional Uses (Historical & Cultural Context – Non-Medical)
Gentian root has a long history in European and Asian herbal traditions. Historically, extracts containing Gentiopicroside were used to add bitterness to tonics, spirits, and digestive preparations. Today, Gentiopicroside is widely studied for its natural bitter compounds, which can influence sensory profiles and support formulation development in modern supplement and beverage industries.
6. Usage Guide & Formulation Suggestions
Not medical instructions; general industry practice only.
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Supplement dosage (industry practice):
50–300 mg/day depending on formulation design -
Common formats:
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Capsules & tablets
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Liquid shots
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Beverage bitters
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Functional foods
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Botanical reference standards
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Formulation Tips:
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Combine with ginger, citrus extracts, or digestive herb blends
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Use microencapsulation to reduce bitterness
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Dissolves well in warm water and ethanol
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7. Full COA
(Values are typical batch standards; customizable COA available.)
7.1 Assay & Physical Data
| Item | Specification | Method |
|---|---|---|
| Appearance | White powder | Visual |
| Identification | Positive | HPLC |
| Assay (Gentiopicroside) | ≥ 98% | HPLC |
| Moisture | ≤ 3.0% | USP <731> |
| Ash | ≤ 2.0% | USP <281> |
7.2 Pesticide Residues
| Item | Limit | Method |
|---|---|---|
| 500+ Multi-residue pesticides | Complies | GC-MS/MS |
| Organochlorine pesticides | ≤ 0.1 ppm | GC-MS |
| Organophosphorus pesticides | ≤ 0.1 ppm | GC-MS |
7.3 Heavy Metals
| Item | Limit | Method |
|---|---|---|
| Lead (Pb) | ≤ 2 ppm | ICP-MS |
| Arsenic (As) | ≤ 1 ppm | ICP-MS |
| Mercury (Hg) | ≤ 0.1 ppm | ICP-MS |
| Cadmium (Cd) | ≤ 1 ppm | ICP-MS |
| Total Heavy Metals | ≤ 10 ppm | ICP-MS |
7.4 Microbiology
| Item | Limit | Method |
|---|---|---|
| Total Plate Count | ≤ 1,000 cfu/g | ISO |
| Yeast & Mold | ≤ 100 cfu/g | ISO |
| E. coli | Negative | ISO |
| Salmonella | Negative | ISO |
| Staphylococcus aureus | Negative | ISO |
8. Production Process
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Raw material inspection & cleaning
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Water-ethanol extraction
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Filtration & concentration
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Column chromatographic purification
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Solvent removal
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Vacuum drying
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Milling & sieving
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Final HPLC verification
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Packaging in GMP clean room
9. Storage & Shelf Life
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Storage: Cool, dry, sealed environment; avoid direct sunlight
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Shelf Life: 24 months unopened
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Transportation: Stable during air or sea freight
10. Packaging & Samples
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Standard Packaging: 1 kg aluminum foil bag; 25 kg fiber drum
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OEM Packaging: Available for customized herbal extract projects
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Samples: Free sample herbal extract available for testing
11. MOQ & Shipping
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MOQ: 1 kg
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Bulk order discounts: Available upon request
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Shipping: DHL / FedEx / UPS / air cargo / sea freight
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Lead Time: 3–7 working days
12. Suitable Industries
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Dietary supplements
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Functional foods & beverages
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Bitters and botanical formulations
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Cosmetic actives
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Pharmaceutical R&D
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Academic phytochemistry research
13. Application Scenarios
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Capsule & tablet manufacturing
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Flavor/bitter enhancers for beverages
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Botanical standard reference material
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Natural wellness formulations
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R&D ingredient screening
14. FAQ
1. Do you offer third-party testing?
Yes, HPLC, microbials, ICP-MS, and pesticide tests are available.
2. Can I request customized purity?
Yes, we can produce customized herbal extract grades depending on your application.
3. Do you support OEM/ODM?
Yes, we are a botanical extract manufacturer offering custom formulations and blends.
4. What’s your best bulk price?
Bulk price depends on quantity; contact us for the latest quote.
5. Do you ship worldwide?
Yes, we export to Europe, North America, Southeast Asia, and the Middle East.
15. Factory Background
AIHerba® | Shaanxi Zhonghong Investment Technology Co., Ltd.
We are a GMP-certified herbal extract supplier with more than 28 years of production experience. Our facility integrates modern extraction technologies—supercritical CO₂, water-ethanol extraction, microbial fermentation—supported by an in-house R&D lab capable of HPLC, UV, TLC, and microbiological testing.
We supply bulk herbal extracts for cosmetics, pharmaceutical health products, functional foods, and dietary supplements. As a long-term plant extract factory in China, we provide consistent quality, fast delivery, competitive prices, and full supply-chain traceability.
16. References (PubMed / NIH / Academic Sources)
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PubChem – Gentiopicroside structural data: https://pubchem.ncbi.nlm.nih.gov
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NIH – Natural products research database
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PubMed articles on Gentiana phytochemistry
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European Pharmacopoeia monographs on Gentiana
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FDA GRAS botanical guidelines
17. Contact Information
📧 sales@aiherba.com
📧 info@aiherba.com
📧 liaodaohai@gmail.com
🌐 www.aiherba.com





