1. Berberine Hydrochloride – Premium Bulk Supply for B2B Buyers
Berberine Hydrochloride is a high-purity alkaloid extract widely recognized for its health-promoting properties. Sourced from Berberis species and manufactured under strict GMP conditions, our Berberine Hydrochloride is optimized for pharmaceutical, nutraceutical, and dietary supplement applications. With COA-verified purity ≥ 98% (HPLC), low heavy metal content, and rigorous microbial safety testing, it ensures consistent quality for large-scale industrial use. Trusted by leading manufacturers worldwide, we offer customized packaging, fast delivery, and competitive MOQ for bulk purchases. Whether you are formulating capsules, tablets, functional foods, or beverages, our Berberine Hydrochloride is the ideal choice for reliable, safe, and effective product development.
2. Product Overview
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English Name: Berberine Hydrochloride
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CAS Number: 633-65-8
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Molecular Formula: C20H18ClNO4
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Appearance: Yellow to orange crystalline powder
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Solubility: Water-soluble, slightly soluble in ethanol
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Purity: ≥ 98% (HPLC)
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Shelf Life: 2 years when stored properly
Berberine Hydrochloride Dietary Supplements -
Storage Conditions: Cool, dry, and dark place
3. Product Source
Berberine Hydrochloride is extracted from the roots, stems, and bark of Berberis vulgaris and Coptis chinensis through ethanol-water extraction, followed by purification and crystallization. Our factory uses controlled solvent recovery systems to ensure environmental safety and product consistency.
4. Benefits & Health Effects
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Supports healthy blood sugar levels and glucose metabolism.
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Promotes cardiovascular health by aiding lipid regulation.
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Enhances digestive function and gut microbiome balance.
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Exhibits anti-inflammatory and antioxidant properties.
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Provides potential support for weight management.
5. Traditional Applications
Historically, Berberine has been used in Traditional Chinese Medicine (TCM) to treat gastrointestinal issues, infections, and metabolic disorders. Modern applications include dietary supplements, functional beverages, and herbal formulations.
6. Usage Guidelines & Recommended Dosage
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Typical dosage in nutraceuticals: 200–500 mg/day
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Dosage may vary depending on formulation, target application, and local regulations.
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Always consult regulatory guidelines for dosage limits in specific markets.
Application Methods:
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Capsules & tablets
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Functional drinks and powders
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Topical solutions (cosmetic & medicinal)
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Health supplements
7. Best Formulation Practices
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Combine with compounds that enhance absorption (e.g., piperine).
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Avoid direct mixing with strong acids or bases.
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Maintain proper storage and encapsulation to prevent oxidation.
8. Product Specifications & COA Table
| Category | Item | Specification | Test Method |
|---|---|---|---|
| Pesticide Residue | Total Pesticides | ≤ 0.01% | GC-MS / HPLC |
| Organophosphates | ND | GC-MS | |
| Carbamates | ND | GC-MS | |
| Heavy Metals | Lead (Pb) | ≤ 0.5 mg/kg | AAS |
| Arsenic (As) | ≤ 0.2 mg/kg | AAS | |
| Mercury (Hg) | ≤ 0.1 mg/kg | AAS | |
| Cadmium (Cd) | ≤ 0.3 mg/kg | AAS | |
| Microbial | Total Plate Count | ≤ 1000 CFU/g | AOAC 990.12 |
| Yeast & Mold | ≤ 100 CFU/g | AOAC 997.02 | |
| E. coli | Negative | USP <2022> | |
| Salmonella | Negative | USP <2022> |
ND = Not Detected
9. Production Process
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Raw material selection & inspection
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Cleaning, drying, and pulverization
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Ethanol-water extraction
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Filtration & concentration
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Crystallization & purification
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Drying & milling to powder
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Packaging & QC testing
10. Storage, Shelf Life & Packaging
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Storage: Cool, dry, and dark place (≤25°C, <60% RH)
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Shelf Life: 24 months from production date
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Packaging Options: 25 kg/drum, 1 kg/aluminum foil bag, or customized
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Sample Policy: Small trial samples available upon request
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Shipping: Sea freight, air freight, and express delivery supported
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MOQ: 10 kg (negotiable for larger orders)
11. Applicable Industries & Use Cases
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Pharmaceuticals: Tablets, capsules, health drugs
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Nutraceuticals: Functional foods, weight management supplements
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Beverage Industry: Herbal teas, functional drinks
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Cosmetics: Anti-aging creams and skin care products
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Food Industry: Fortified food powders and beverages
12. Experience & Authority
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Over 15 years of GMP-certified production experience
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Trusted supplier for European, North American, and Asian manufacturers
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Third-party verified COA and safety compliance (ISO, HACCP)
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Real factory photos and on-site verification available
13. Common Questions (FAQ)
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Q: Is Berberine Hydrochloride suitable for capsule formulation?
A: Yes, it is highly compatible with hard-shell and softgel capsules. -
Q: What is the solubility of Berberine Hydrochloride?
A: Water-soluble; slightly soluble in ethanol. -
Q: Can you provide COA and safety documentation?
A: Yes, COA, heavy metal reports, microbial reports, and pesticide residue tests are provided for all batches. -
Q: Do you offer custom packaging?
A: Yes, packaging and labeling can be customized according to buyer requirements.
14. References & Regulatory Sources
15. Contact & Verification
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Company: Shaanxi Zhonghong Investment Technology Co., Ltd.
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Website: aiherba.com
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Email: sales@aiherba.com / info@aiherba.com
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Brand Verification: On-site audits and third-party lab reports available
