1. 5-Hydroxytryptophan Extract – GMP Bulk Supplier & OEM Manufacturer

AIHerba® supplies high-purity 5-Hydroxytryptophan (5-HTP) extract for global nutraceutical, dietary supplement, and functional food manufacturers seeking reliable bulk sourcing and OEM/ODM solutions. Produced under GMP-certified conditions, our 5-HTP is manufactured with strict raw material control, validated analytical testing, and full batch traceability, ensuring consistency, safety, and regulatory readiness for international markets.

As an experienced China-based 5-HTP manufacturer and exporter, AIHerba® supports professional buyers with customized specifications, complete COA documentation, scalable production capacity, and stable long-term supply. Our ingredient is suitable for capsules, tablets, powders, and compound formulations, meeting the technical needs of brand owners, contract manufacturers, and R&D teams worldwide.

We focus on ingredient quality, formulation compatibility, and compliance transparency, helping partners reduce sourcing risk and accelerate product development without exaggerated health claims.

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2. What Is 5-Hydroxytryptophan (5-HTP)?

5-Hydroxytryptophan (5-HTP) is a naturally occurring amino acid derivative and an intermediate metabolite in the biosynthesis of serotonin. In commercial applications, 5-HTP is primarily extracted from the seeds of Griffonia simplicifolia, a plant native to West Africa.

In the nutraceutical industry, 5-HTP is widely used as a functional ingredient due to its role as a serotonin precursor, making it a common component in formulations related to mood balance, sleep support, and stress management, when used in accordance with regional regulatory frameworks.

⚠️ This ingredient is supplied as a raw material, not as a finished dietary supplement or medical product.

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3. Product Technical Specifications

5-HTP Extract – Technical Parameters

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4. Botanical Source & Raw Material Origin

AIHerba® sources non-GMO Griffonia simplicifolia seeds from qualified suppliers, applying supplier audits, identity testing, and contaminant screening before production. Raw materials are processed under controlled conditions to maintain ingredient integrity and batch consistency.

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5. Mechanism of Action & Functional Role (Non-Therapeutic)

From a biochemical perspective, 5-HTP functions as an immediate precursor to serotonin in human metabolic pathways. In finished products, it is typically positioned as a functional nutritional ingredient, not as a treatment or cure.

Key formulation roles include:

• Supporting neurotransmitter synthesis pathways

• Ingredient synergy in mood-related formulations

• Compatibility with vitamin B-complex and botanical blends

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6. Usage Guidance & Formulation Considerations

Recommended Industry Usage (For Manufacturers Only)

Final dosage and claims must comply with local regulatory requirements (FDA, EFSA, etc.).

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7. Traditional & Historical Use Context

Griffonia simplicifolia has a history of traditional use in West African botanical practices, primarily as a plant resource. Modern extraction methods isolate 5-HTP for standardized industrial applications.

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8. Safety Considerations & Compliance Notes

• Intended for professional formulation use only

• Not recommended for use alongside serotonergic medications without professional evaluation

• Labeling and claims must follow regional food supplement regulations

• COA, MSDS, and technical dossiers available upon request

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9. Certificate of Analysis (COA) – Quality Control Overview

A. Pesticide Residue Testing

B. Heavy Metals

C. Microbiological Tests

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10. Manufacturing Process & Production Flow

1. Raw material inspection & identity verification

2. Controlled extraction (water-ethanol method)

3. Purification & concentration

4. Crystallization & drying

5. Milling & particle size control

6. In-process quality testing

7. Final inspection & packaging

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11. Storage, Shelf Life & Packaging

• Storage: Cool, dry place, protected from light

• Shelf Life: 24 months under recommended conditions

• Packaging Options:

  • 1 kg / 5 kg / 25 kg fiber drums

  • Double PE inner bags

  • Customized OEM packaging available

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12. Sample Policy, MOQ & Logistics

• Free Samples: Available for qualified B2B buyers

• MOQ: 1 kg (bulk pricing available for larger volumes)

• Shipping: Air, sea, or express courier

• Lead Time: 3–7 working days for standard specs

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13. Clinical Data & Recent Research (Reference Only)

• NIH: Serotonin biosynthesis pathways

• PubMed: 5-HTP metabolic studies

• FDA: Dietary ingredient compliance guidance

(See references section below)

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14. Applicable Industries & Use Scenarios

Industry Applications

• Dietary supplements

• Functional nutrition products

• Contract manufacturing (OEM/ODM)

• Research & formulation development

Practical Application Scenarios

Scenario 1 – Capsule Manufacturing
Used as an active ingredient in standardized capsule formulations combined with vitamins and minerals.

Scenario 2 – Functional Powder Blends
Incorporated into powdered nutrition mixes for controlled-dose formulations.

Scenario 3 – R&D Ingredient Testing
Utilized by formulation labs for stability and compatibility testing.

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15. Supplier Comparison & Procurement Guidance

When selecting a 5-HTP supplier, professional buyers should evaluate:

• Purity & analytical verification

• GMP certification & traceability

• Regulatory documentation readiness

• Production capacity & supply stability

AIHerba® focuses on long-term B2B partnerships, not short-term trading.

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16. B2B Buyer FAQ

Q1: Do you provide full COA and MSDS?
✔ Yes, available for every batch.

Q2: Is OEM labeling supported?
✔ Yes, OEM & ODM services available.

Q3: What purity levels do you offer?
✔ Standard ≥98%, customization possible.

Q4: Is the product compliant with FDA dietary ingredient requirements?
✔ Supplied with compliance documentation for review.

Q5: Can you support large-volume contracts?
✔ Yes, scalable production capacity.

Q6: Do you offer formulation support?
✔ Technical guidance available for qualified partners.

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17. References & Regulatory Sources

• PubMed: https://pubmed.ncbi.nlm.nih.gov

• NIH: https://www.nih.gov

• FDA Dietary Supplements: https://www.fda.gov/food/dietary-supplements

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Manufacturer & Quality Assurance

Manufactured by AIHerba® (Shaanxi Zhonghong Investment Technology Co., Ltd.),
a GMP-certified manufacturer specializing in high-purity botanical extracts
for dietary supplements, cosmetics, and pharmaceutical applications.

✔ GMP-certified production facility
✔ Full COA & technical specifications available
✔ Batch traceability & strict quality control
✔ Bulk supply & OEM/ODM services for global B2B buyers

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Author

Reviewed by: PhD in Food Science / Formulation Specialist