Bulk Fisetin 98% Supplier | High Purity Senolytic Isolate
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Fisetin 98% Powder | CAS 528-48-3 | Pharma Grade Bulk

  1. Product Name: Fisetin Powder (Cotinus coggygria Extract) | Industrial Bulk Supply

  2. Assay (HPLC): ≥ 98% (Certified 3,3′,4′,7-Tetrahydroxyflavone Isolate)

  3. Appearance: Yellow Fine Crystalline Powder (Uniform Particle Size)

  4. CAS No.: 528-48-3

  5. Solubility: Soluble in Ethanol and DMSO; Practically Insoluble in Water

  6. Stability: Thermally Stable; Optimal in Nitrogen-Sealed, Light-Protected Environments

  7. Lead Time: 3–7 Working Days (Global Bulk Stock)

  8. Packaging: 25kg Standard Drum / 1kg Sample Available

  9. Compliance: GMP Certified / Full Batch COA & TDS Provided

  10. Application: Advanced Senolytic Supplements / Anti-Aging Formulations / OEM/ODM

Bulk Supply & Technical Advisory
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GMP Certified
🔬
HPLC Lab Tested
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Global Logistics
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Free Samples

Industrial Sourcing Entry

01. Fisetin Bulk Supplier — Procurement Summary

Standardized 98% HPLC extract for global supplement, cosmetic, and pharmaceutical manufacturing.

Manufacturer: AIHerba® (Direct Factory)
Supply Form: Fine Crystalline Powder
MOQ: 1kg (Sample) / 25kg (Industrial Drum)
Lead Time: 3–7 Working Days
Compliance: USP / Prop 65 / FSMA Ready
Global Export: DDP / CIF / FOB (80+ Countries)

SECURE WHOLESALE PRICE

02. Manufacturer & Quality Assurance Platform

AIHerba® Industrial Infrastructure

Operated by Shaanxi Zhonghong Investment Technology Co., Ltd., AIHerba provides a vertically integrated manufacturing system. We bridge the gap between “Cheap Commodity” and “Overpriced Pharma” by delivering 15/18 Parameter Match quality directly from our GMP-certified facility.

✔ GMP Manufacturing
✔ Batch Traceability
✔ Raw Material Control
✔ DDP Logistics Green Lane

03. Fisetin Identity Profile

Chemical Name 3,3′,4′,7-Tetrahydroxyflavone
CAS Number 528-48-3
Source Cotinus coggygria (Smoketree) – Natural Extract
Extraction Method Phyto-Preserve™ (Low Temperature / High Purity)
Grade Cosmetic / Nutraceutical / Pharmaceutical

04. Technical Specification & Release Standard

PURITY (HPLC)

≥ 98.0%

RESIDUAL SOLVENT

n-Hexane ≤ 1 ppm

HEAVY METALS

≤ 10 ppm

MESH SIZE

80 – 100 Mesh

05. Analytical Verification & Scientific Fingerprint

We bridge the trust gap by providing raw analytical evidence. For A-Class R&D clients, we provide full structural confirmation to ensure zero isomer blending.

HPLC-DAD
Identity & Purity
1H-NMR
Structural Fingerprint
HS-GC-FID
Residual Solvent

* Illustrative Technical Simulation: Typical batch release profile available upon request.

06. Batch Release & Quality Control System

01 Raw Material Inspection
02 Precision Extraction
03 Laboratory Testing
04 Batch Release (QA)

07. Manufacturing Process & Engineering Control

AIHerba’s Fisetin isolation utilizes Multi-stage Low-temperature Extraction followed by double recrystallization. This engineering control avoids the use of high-risk solvents like n-Hexane or Toluene, ensuring the resulting crystalline habit is clean-label compliant and stable for long-term storage.

08. Molecular Structure & Functional Characteristics

Fisetin is a bioactive flavonol molecule with a planar polyphenolic structure. Its industrial importance lies in its Senolytic Property—the ability to selectively induce apoptosis in senescent cells. AIHerba Fisetin maintains its molecular integrity through high-purity isolation, supporting neuro-protective and anti-aging research applications.

09. Industrial Application Compatibility

Nutraceutical Formulations

Optimal for Longevity/Senolytic capsule and powder blends.

Dermaceutical Topicals

Functional antioxidant property for high-end skincare serums.

Nootropic Products

Supportive active for neuro-protective and memory enhancement research.

10. Formulation Development Guide

Solubility

Lipophilic. Soluble in Ethanol and DMSO. Pair with piperine or lipid-based delivery systems to enhance oral bioavailability.

Manufacturing Habit

100-mesh powder is optimized for high-speed encapsulation. Avoid direct light during production to prevent oxidation.

11. Stability & Transport Engineering

Risk: Oxidative Degradation
Fisetin’s polyphenolic indole core is sensitive to long-term oxygen exposure, leading to assay loss and darkening.
Solution: Nitrogen-Blanket Packaging & Argon-purged headspace control in primary PE liners.
Engineering: Thermal Stability
Extreme temperature fluctuations during cross-ocean transit can affect crystalline habit.
Impact: Batch integrity maintained through validated temperature-monitored DDP logistics.

12. Regulatory & Compliance Documentation

📑
Full COA
Batch-Specific
⚖️
MSDS / SDS
Global GHS
🛡️
TDS / Specification
Standardized
🔬
NMR / HPLC
Identity Proof

13. Packaging Storage & Global Shipping

  • Packaging: Standard 25kg medical-grade fiber drum with double-layer LDPE liners. 1kg vacuum foil bags for R&D trials.
  • Storage: Cool, dry conditions (<20°C) with <40% humidity. Shield from direct UV radiation.
  • Shipping: Express DDP (Duty Paid) available for USA, EU, and UK, bypassing port friction through our pre-cleared green lane.

14. Custom Specification & OEM Support

AIHerba® provides Particle Engineering for automated production lines. We can supply Fisetin in custom mesh sizes (80-200 mesh) to optimize flowability for high-speed encapsulation. Private Labeling and Custom Premixes (e.g., Fisetin + Quercetin) are available for industrial scale-up.

15. Fisetin Market & Industry Insights

The global senolytic market is projected to expand by 12.5% CAGR, with Fisetin emerging as the preferred active for longevity brands. As a primary manufacturer, AIHerba is capturing this demand by providing Hexane-Free grades that satisfy the “Clean Label” requirements of North American and European premium retailers.

16. Market Benchmark Comparison

Metric Standard Trader Supply AIHerba® Industrial Grade
Identity Proof Basic HPLC SEC-GPC + 1H-NMR Spectra
n-Hexane Residue ≤ 290 ppm Non-Detected (< 1 ppm)
Traceability Multi-Broker Vertical Farm-to-Drum Control
Audit Support None FSMA / GMP Site Audit Ready

17. Technical Procurement FAQ

Q1: What molecular weight options are available for industrial scale?
AIHerba provides standardized Fisetin at 286.24 g/mol. For formulation-specific needs, we offer micronized grades with D90 < 20µm for enhanced oral absorption.
Q2: How does AIHerba achieve < 1ppm n-Hexane residues?
We utilize the Phyto-Preserve™ process, a closed-loop ethanol extraction system combined with high-vacuum stripping, eliminating the need for industrial-grade Hexane.
Q3: Can you support FSMA / cGMP on-site factory audits?
Yes, AIHerba (Shaanxi Zhonghong) welcomes quality audits from strategic partners. We provide a full technical pack for supplier qualification.
Q4: What is the lead time for a 500kg bulk DDP order to the USA?
For stocked material, dispatch occurs within 3 days. Total transit door-to-door is typically 12-14 days via our pre-cleared air lane.
Q5: Is AIHerba Fisetin compliant with California Prop 65?
Yes. Every industrial batch is tested via ICP-MS to ensure Lead (Pb) < 0.1 ppm, exceeding USP heavy metal standards.
Q6: How do you verify you have Fisetin and not a generic flavonoid isomer?
We utilize 400MHz 1H-NMR structural finger-printing. This identifies the specific chemical shifts of 3,3′,4′,7-Tetrahydroxyflavone, ensuring molecular identity.
Q7: Can I request a customized COA for specific R&D parameters?
Absolutely. We can perform additional testing for pesticides, specific residual solvents, or particle size distribution according to your quality control protocol.
Q8: What is the shelf life stability of the material in a 25kg drum?
Standard shelf life is 24 months. Our ICH stability reports show >99% assay retention when stored in a cool, dry, nitrogen-sealed environment.
Q9: Are your extraction solvents USP <467> compliant?
Yes. We only use Class 3 solvents (Ethanol/Water) in the final purification stages, ensuring total compliance with international pharmacopeia.
Q10: Do you provide logistical support for VAT and customs duties in Europe?
Under DDP terms, AIHerba handles all EU import duties and VAT. Your procurement team receives the goods directly at the warehouse with zero administrative friction.

18. AIHerba Industrial Quality Commitment

✔ GMP Manufacturing
✔ Batch Traceability
✔ Analytical Release
✔ Technical Dossier
✔ OEM Support
✔ Global Export

Contact our engineering department for samples or custom specifications.


Bulk Supply & Technical Advisory
🛡️
GMP Certified
🔬
HPLC Lab Tested
🌍
Global Logistics
📦
Free Samples
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