L-Theanine: Premium Calm-Focus Ingredient for Nutraceutical & Functional Food Applications – Manufacturer & Exporter Guide
1. What is L-Theanine?
For product developers seeking scientifically-backed nootropic ingredients, L-Theanine represents one of nature’s most remarkable compounds for promoting calm focus. This unique amino acid analogue, primarily found in green tea leaves (Camellia sinensis), has gained significant recognition for its ability to promote relaxation without drowsiness while enhancing cognitive performance. Unlike synthetic relaxants, our pharmaceutical-grade L-Theanine offers a natural solution for stress management and mental clarity, making it increasingly sought-after for nutraceutical, functional food, and beverage applications where both safety and efficacy are paramount.
2. Source, Chemistry & Specifications
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Source: Fermentation-derived using advanced biotechnology (non-GMO)
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Chemical Identity: γ-glutamylethylamide or N-ethyl-L-glutamine
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Chemical Profile:
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CAS No.: 3081-61-6
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MF: C₇H₁₄N₂O₃
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MW: 174.20 g/mol
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EINECS: 221-379-9
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Appearance: White crystalline powder
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Solubility: Freely soluble in water; slightly soluble in ethanol
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Purity Grades: 98.5-101.5% USP/EP/JP pharmacopeial standards
3. The Pharmaceutical Standard: Why Our L-Theanine Excels
For B2B clients requiring guaranteed quality and consistency, our L-Theanine delivers superior performance:
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Key Advantages:
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Dual-Action Benefits: Promotes relaxation while maintaining mental alertness
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Excellent Safety Profile: Well-tolerated with no known side effects at recommended doses
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Synergistic Formulations: Complements caffeine and other nootropics effectively
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Clinically Demonstrated Benefits:
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Stress Reduction: Promotes alpha brain waves associated with relaxed alertness
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Cognitive Enhancement: Improves attention, focus, and cognitive performance
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Sleep Quality: Supports restful sleep when taken before bedtime
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Mood Support: Contributes to overall emotional balance and well-being
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Recommended Dosage: 100-400 mg daily in supplements; 25-100 mg in functional beverages
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Certifications Available: USP, EP, JP, cGMP, ISO 9001, Kosher, Halal, Non-GMO
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Target Applications: Stress relief supplements, nootropic formulations, sleep aids, functional beverages
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Safety Profile: Generally Recognized as Safe (GRAS); excellent safety profile
4. Shaanxi Zhonghong Investment Technology Co., Ltd.: Your Trusted Manufacturing Partner
Sourcing premium-grade L-Theanine requires advanced fermentation expertise. Our company combines 28 years of biochemical manufacturing experience with state-of-the-art fermentation technology to deliver pharmaceutical-grade L-Theanine to global markets.
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Technical Capabilities:
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Advanced Fermentation: Precision-controlled fermentation using non-GMO microorganisms
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Purification Expertise: Multi-stage crystallization and purification processes
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Quality Assurance: Comprehensive testing exceeding pharmacopeial requirements
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Global Compliance: Full documentation meeting international regulatory standards
5. Scientific Excellence: Mechanism of Action
L-Theanine’s unique effects stem from multiple neurological mechanisms:
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Increases alpha brain wave activity associated with relaxed alertness
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Modulates neurotransmitter levels including GABA, dopamine, and serotonin
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May protect brain cells from excitotoxicity and stress-induced damage
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Supports the production of brain-derived neurotrophic factor (BDNF)
6. Pharmaceutical-Grade Quality Assurance
Our rigorous quality control ensures every batch meets the highest standards:
Certificate of Analysis (COA) Summary – L-Theanine (USP Grade)
Category | Parameter | Specification | Test Method |
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Identity | Optical Rotation | +7.0° to +9.0° | USP <781> |
Assay | L-Theanine Content | 98.5-101.5% | HPLC |
Purity | Related Substances | ≤ 0.5% | HPLC |
Safety | Heavy Metals | ≤ 10 ppm | ICP-MS |
Residual Solvents | Meet ICH Guidelines | GC | |
Microbiology | Total Plate Count | ≤ 1000 CFU/g | USP <61> |
Yeast/Mold | ≤ 100 CFU/g | USP <61> |
7. Advanced Manufacturing Process
Our pharmaceutical-grade production ensures superior quality:
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Fermentation Process: Controlled fermentation using non-GMO microorganisms
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Separation & Purification: Multi-stage purification and crystallization
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Crystallization: Precision crystallization for optimal purity
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Drying: Controlled drying to optimal moisture content
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Milling: Precision particle size control
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Quality Control: Comprehensive analytical testing
8. Professional Applications & Usage
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Nutraceuticals: Stress relief formulas, nootropic stacks, sleep supplements
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Functional Foods: Relaxation beverages, cognitive enhancement products
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Pharmaceuticals: Anxiety management, cognitive support formulations
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Cosmeceuticals: Stress-relief skincare products
Usage Guidelines:
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Dietary Supplements: 100-400 mg per serving
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Functional Beverages: 50-200 mg per serving
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Nootropic Formulations: 100-200 mg combined with caffeine (2:1 ratio)
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Sleep Aids: 200-400 mg taken 30-60 minutes before bedtime
9. Global Supply Chain Excellence
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Packaging: 25kg fiber drums with double polyethylene liners
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Storage: Cool, dry conditions in original packaging
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Shelf Life: 36 months when stored properly
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Logistics: Global shipping with full documentation support
10. Partnership Opportunities
We offer:
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Custom particle sizes for specific formulation needs
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Private labeling and custom packaging options
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Technical support for product development
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Regulatory documentation for global market access
Contact Our Technical Team:
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Web: www.aiherba.com
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Keywords: L-Theanine supplier, bulk L-Theanine manufacturer, nootropic ingredients supplier, functional beverage ingredients, stress relief supplement ingredients
11. Technical FAQ
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Q: What’s the difference between L-Theanine and Suntheanine?
A: Suntheanine is a patented form of pure L-Theanine; our product meets the same purity standards -
Q: Can L-Theanine be used with caffeine?
A: Yes, it’s particularly effective when combined with caffeine in a 2:1 ratio (L-Theanine:caffeine) -
Q: What documentation do you provide?
A: Comprehensive COA, MSDS, and regulatory support documents -
Q: Is your L-Theanine suitable for vegan products?
A: Yes, our fermentation-derived L-Theanine is 100% vegan-friendly -
Q: What’s your minimum order quantity?
A: MOQ is 25kg for production quantities, with sample quantities available
12. Final Call to Action
Experience the superior quality of our pharmaceutical-grade L-Theanine for your formulations. Contact us today to discuss your specific requirements and request samples for your product development.
Contact us now for technical specifications and samples:
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Email: sales@aiherba.com
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Website: www.aiherba.com
References:
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USP43-NF38. (2020). L-Theanine Monograph. United States Pharmacopeia
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EFSA Panel on Dietetic Products. (2017). Scientific Opinion on L-Theanine
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Journal of Clinical Psychiatry. (2019). L-Theanine for Stress and Anxiety
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FDA. (2023). Generally Recognized as Safe (GRAS) substances
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For best results: Pair 200mg L-Theanine with 100–150mg caffeine (about a cup of coffee)—this combo is called the “golden ratio” for calm focus. If you’re sensitive to caffeine, take it alone 30 minutes before bed to wind down.