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อัลฟา-คีโตกลูตาเรต

  1. ภาพรวมผลิตภัณฑ์
    English Name: Alpha-Ketoglutarate, often abbreviated as AKG
    Chemical Nature: It is a key intermediate in the Krebs cycle (also known as the citric acid cycle), which is central to cellular energy metabolism. AKG plays a crucial role in various biochemical processes within the body.
  2. ข้อมูลจำเพาะ:Purity: Alpha-Ketoglutarate ≥ 98% (HPLC – tested). Stringent production and purification methods are employed to achieve this high level of purity. Rigorous quality control ensures minimal contaminants, such as heavy metals and microbial impurities, conforming to international standards for dietary supplements, cosmetics, and food ingredients.
  3. รูปร่าง:It appears as a white crystalline powder. The powder is odorless or has a very faint, characteristic smell. It is free – flowing, facilitating its use in different formulations.
  4. แคส NO.: 328 – 50 – 7. This unique identifier is essential for chemical identification, research, and regulatory compliance.
  5. ระยะเวลาดำเนินการ: 3 – 7 วันทำการ อาจมีการปรับเปลี่ยนเล็กน้อยขึ้นอยู่กับปริมาณการสั่งซื้อและกำลังการผลิต ระบบการผลิตและโลจิสติกส์ที่มีประสิทธิภาพของเราออกแบบมาเพื่อให้มั่นใจว่าจะส่งมอบสินค้าได้ตรงเวลา
  6. บรรจุุภัณฑ์:25 กก./ถัง บรรจุ 27 ถัง/ถาด ถังทำจากวัสดุเกรดอาหาร ช่วยป้องกันความชื้น แสง และความเสียหายทางกายภาพได้อย่างดีเยี่ยมระหว่างการจัดเก็บและขนส่ง มีตัวเลือกบรรจุภัณฑ์แบบกำหนดเองได้ตามคำขอ
  7. ตลาดหลัก: European, North America, Asia etc. It has a global market presence. In Europe and North America, it has gained significant popularity among fitness enthusiasts, athletes, and those interested in anti – aging and longevity research. In Asia, with a growing focus on health and wellness, it is also attracting attention.
  8. แอปพลิเคชัน
    • อาหารเสริมเพื่อสุขภาพ:
      • Energy Production: AKG is involved in the generation of adenosine triphosphate (ATP), the body\’s primary energy currency. Supplementing with AKG can potentially enhance athletic performance, reduce fatigue during exercise, and support overall physical endurance.
      • Muscle Building: It may contribute to muscle protein synthesis, helping to build and maintain lean muscle mass. This is beneficial for bodybuilders and those looking to improve their body composition.
      • Anti – aging: Some studies suggest that AKG can extend lifespan in certain organisms. In humans, it may help maintain cellular health by supporting mitochondrial function and protecting cells from oxidative stress, potentially slowing down the aging process.
    • เครื่องสำอาง:
      • ฟื้นฟูผิว: ผลกระทบต่อเซลล์ผิวที่ชะลอวัย ได้แก่ การส่งเสริมการสังเคราะห์คอลลาเจน ลดเลือนริ้วรอย และเสริมสร้างความยืดหยุ่นของผิว นอกจากนี้ยังช่วยปกป้องเซลล์ผิวจากภาวะเครียดออกซิเดชัน ส่งผลให้ผิวดูอ่อนเยาว์ยิ่งขึ้น
      • ซ่อมแซมผิว: คุณสมบัติต้านอนุมูลอิสระและต้านการอักเสบของผิว มีประสิทธิภาพในการซ่อมแซมผิวที่เสียหาย บรรเทาอาการระคายเคือง และส่งเสริมการสมานผิว มีประโยชน์ต่ออาการต่างๆ เช่น สิว กลาก และสะเก็ดเงิน
    • อุตสาหกรรมอาหาร:
      • Functional Foods: Incorporated into sports nutrition products, energy drinks, and fortified cereals to enhance their nutritional value. It offers consumers a natural way to boost their energy levels and support overall well – being.
      • Nutraceutical Beverages: Can be used in specialty drinks aimed at providing anti – aging and performance-enhancing benefits, making them more appealing to health – oriented consumers.

Alpha-Ketoglutarate (AKG): Your Final Information from Premium Provider Aiherba

1. What’s Alpha-Ketoglutarate (AKG)?
Consider AKG as your mobile powerhouse’s spark plug. This significant molecule sits proper within the coronary heart of the Krebs cycle (aka citric acid cycle), the engine room the place your cells convert meals into usable vitality (ATP). It is not simply an vitality participant; AKG acts as an important nitrogen scavenger, helps make necessary amino acids like glutamate and glutamine, and even influences mobile signaling pathways associated to growing old and metabolism. It is elementary biochemistry in motion inside your physique each second.

2. AKG Deep Dive: Supply, Chemistry & Key Specs

Alpha-Ketoglutarate Applications
Alpha-Ketoglutarate Purposes
  • จัดหา: Whereas naturally produced within the physique, industrial AKG (like ours) is often produced by means of exact microbial fermentation – assume extremely managed situations utilizing specialised micro organism or yeast strains. This ensures consistency and excessive purity. We แต่เพียงผู้เดียว use premium, traceable beginning supplies.

  • โปรไฟล์ทางเคมี:

    • ปริมาณ CAS: 328-50-7

    • ระบบโมเลกุล: C₅H₆O₅

    • น้ำหนักโมเลกุล: 146.10 g/mol

    • EINECS: 206-330-3

  • ดู: Sometimes a white to off-white crystalline powder.

  • ความสามารถในการละลาย: Extremely soluble in water.

3. การค้นพบ ดีที่สุด AKG: What Really Issues (Aiherba’s Commonplace)
Overlook obscure claims. The ยิ่งใหญ่ที่สุด AKG comes right down to verifiable high quality, purity, and the experience behind it. Here is why Aiherba units the bar:

  • ส่วนผสมหลัก: Pure, Pharmaceutical-Grade Alpha-Ketoglutarate (usually because the Disodium salt for stability/solubility).

  • Unmatched Purity & Security (Our Core Promise): See Part 7 for our exhaustive Certificates of Evaluation (COA) requirements. We take a look at far past fundamentals.

  • Confirmed Efficacy (Compliance Centered): Our AKG is manufactured beneath strict cGMP tips. Whereas AKG itself is well-studied biologically, particular well being การเรียกร้อง require region-specific regulatory approval (like FDA or EFSA). We offer the purest substrate for analysis and product improvement.

  • แหล่งกำเนิดและการผลิต: Proudly researched, developed, and manufactured in our state-of-the-art amenities in China, leveraging 28 years of bio-compound experience. Rigorous high quality management is embedded at each step (See Part 8).

  • How It is Sometimes Used: Integrated into dietary dietary supplements (capsules, tablets, powders), analysis formulations, practical meals/drinks, or cell tradition media. Dosage varies อย่างกว้างขวาง based mostly on software and goal consequence (analysis part vs. completed product). Crucially: Remaining product formulation and dosage willpower ought to be executed by certified professionals.

  • ผู้ชมเป้าหมาย: เป็นหลัก ผู้ผลิต of dietary supplements, sports activities vitamin, practical meals/drinks, and analysis establishments. Additionally utilized by compounding pharmacies.

  • Well being & Wellness Potential (Analysis Insights): AKG is very studied for its potential roles in:

    • Mobile Vitality Manufacturing & Metabolism Assist

    • Amino Acid Synthesis (Glutamate/Glutamine Precursor)

    • Nitrogen Transport & Detoxing

    • Collagen Synthesis Assist

    • Mobile Well being & Longevity Pathways (e.g., influencing TET enzymes/DNA demethylation, modulating mTOR)

    • Train Efficiency & Restoration (analysis ongoing)

  • Every day Consumption & Security: There may be no universally established each day consumption (RDI) for supplemental AKG. Doses in human research fluctuate considerably (e.g., a whole bunch of mg to a number of grams each day). All the time seek the advice of a healthcare supplier earlier than beginning any new complement.

  • Potential Facet Results & Cautions: Usually well-tolerated at widespread supplemental doses. Excessive doses อาจ trigger delicate gastrointestinal upset (like nausea or diarrhea). People with particular well being situations (e.g., kidney illness, most cancers) or taking sure medicines ought to train excessive warning and search medical recommendation. Pregnant/nursing ladies ought to keep away from on account of lack of security knowledge.

4. Your Trusted AKG Associate: Shaanxi Zhonghong Funding Expertise Co., Ltd. (Aiherba)
Overlook faceless ซัพพลายเออร์. Associate with pioneers. Aiherba is not only a โรงงานผลิต; we’re an innovation powerhouse devoted to unlocking nature’s potential for well being and science.

  • จุดเน้นหลัก: Analysis, Joint Innovation, Built-in Manufacturing, World Advertising in Chemistry, Supplies & Life Sciences. We focus on superior extraction, purification, and software of bioactive plant compounds.

  • Premium Portfolio: Pure Extracts, Beauty Actives, Pharma/Well being Substances, Pure Colours, Sweeteners, Meals/Drink Components, Dietary Complement Parts.

  • Unbreakable Scientific Edge (Our “Moat”):

    • 5 Elite College Joint Labs: Reducing-edge analysis at your fingertips.

    • สิทธิบัตรมากกว่า 20 รายการ: Defending groundbreaking purification and synthesis tech.

    • World Unique Compound Library: Entry molecules unavailable elsewhere.

  • Manufacturing Prowess:

    • World-Class QC: HPLC, UPLC, GC-MS, NMR – our purity requirements exceed trade norms by 20%+.

    • Scale & Precision: Geared up for dependable เป็นกลุ่ม manufacturing with out sacrificing high quality.

  • Really World Attain: การเสิร์ฟ 80+ สถานที่ทั่วโลก throughout Asia, Europe, and the Americas. Trusted associate to top-tier pharma, nutraceutical ผู้ผลิต, and analysis giants.

  • 28 ปีลึก: Many years mastering the complexities of bioactive compounds.

5. Why Supply AKG from Aiherba? Tangible Advantages

  • Uncompromising Purity: Important for dependable analysis and efficient end-products.

  • ความสอดคล้องกันแบบชุดต่อชุด: Vital for formulation stability and regulatory compliance.

  • Deep Technical Experience: Leverage our 28 years and PhD workforce to your complicated tasks.

  • Scalability: From R&D samples to full ขายส่ง และ เป็นกลุ่ม portions, we ship.

  • Regulatory Assist: Documentation (COA, MSDS) ready to worldwide requirements.

  • ราคาที่ก้าวร้าว: Excessive-value derived from effectivity and vertical integration, not corner-cutting.

6. Utilizing AKG Successfully

  • วัตถุประสงค์หลัก:

    • Dietary Complement Formulations (Capsules, Tablets, Powders)

    • Sports activities Vitamin & Efficiency Merchandise

    • Purposeful Meals & Beverage Fortification

    • Cell Tradition Media & Biochemical Analysis

    • Beauty Actives (Rising analysis on pores and skin advantages)

  • การจัดการกับ: Retailer in a cool, dry place (<25°C/77°F) in tightly sealed containers. Shield from moisture and light-weight. Commonplace laboratory/complement manufacturing dealing with precautions apply.

7. High quality You Can Measure: Certificates of Evaluation (COA) Specs
We take a look at relentlessly. Here is a snapshot of our stringent AKG requirements:

Desk: Aiherba AKG Certificates of Evaluation (COA) Abstract

ระดับ Check Parameter ข้อมูลจำเพาะ ตรวจสอบวิธีการ
รหัส Alpha-Ketoglutarate (as Disodium) สอดคล้อง HPLC, FTIR
ความบริสุทธิ์ Assay (Anhydrous Foundation) ≥ 99.0% HPLC (USP/EP)
ร่างกาย ดู ผงสีขาวถึงสีออกขาว มองเห็นได้
Solubility (in Water) Clear, Colorless Answer Visible (10% Answer)
Residue การสูญเสียจากการอบแห้ง ≤ 1.0% ยูเอสพี <731>
โลหะหนัก ตะกั่ว (Pb) ≤ 1.0 มก./กก. ไอซีพี-เอ็มเอส (USP <232>/<233>)
สารหนู (As) ≤ 0.5 มก./กก. ไอซีพี-เอ็มเอส (USP <232>/<233>)
แคดเมียม (Cd) ≤ 0.5 มก./กก. ไอซีพี-เอ็มเอส (USP <232>/<233>)
ปรอท (Hg) ≤ 0.1 มก./กก. ไอซีพี-เอ็มเอส (USP <232>/<233>)
ยาฆ่าแมลง สารกำจัดศัตรูพืชทั้งหมด ≤ 0.01 mg/kg (every) GC-MS/MS, LC-MS/MS (EU Reg)
DDT (Sum Isomers) ≤ 0.05 มก./กก. GC-MS/MS, LC-MS/MS (EU Reg)
จุลชีววิทยา Whole Cardio Depend ≤ 1,000 CFU/กรัม USP <61>, EP 2.6.12
ยีสต์และรา ≤ 100 CFU/กรัม USP <61>, EP 2.6.12
อีโคไล ขาดไป 10 กรัม USP <62>, EP 2.6.13
เชื้อ Salmonella spp. ขาดใน 25 กรัม USP <62>, EP 2.6.13
สแตฟิโลค็อกคัส ออเรียส ขาดใน 1 กรัม USP <62>, EP 2.6.13
ซูโดโมแนส แอรูจิโนซา ขาดใน 1 กรัม USP <62>, EP 2.6.13

(This desk represents core specs. Full COA supplied with every batch.)

8. Precision Manufacturing: The Aiherba AKG Manufacturing Circulation
High quality is engineered in, not inspected in. Our course of:

  1. การเลือกความดันและการหมัก: Optimized microbial strains in managed bioreactors.

  2. Harvest & Preliminary Purification: Separation of biomass, preliminary filtration.

  3. การทำให้บริสุทธิ์ด้วยโครมาโตกราฟี: Multi-stage chromatography (Ion Change, Affinity) – the core of our excessive purity. That is the place our patents shine.

  4. การตกผลึกและการแยก: Managed crystallization for optimum particle measurement and purity.

  5. Superior Drying: Lyophilization (Freeze Drying) or mild Spray Drying to protect integrity.

  6. QC ที่เข้มงวด: แต่ละ batch undergoes full battery of exams per COA specs (HPLC, ICP-MS, GC/LC-MS/MS, Microbiology).

  7. บรรจุภัณฑ์ GMP: Sealed in food-grade, moisture-proof containers (HDPE drums or luggage with aluminum liners).

9. The place AKG Makes an Affect: Key Software Eventualities

  • Sports activities & Health: Researching its position in vitality metabolism, fatigue discount, muscle protein synthesis, and restoration assist.

  • Wholesome Growing older: Investigating potential impacts on mobile well being, mitochondrial operate, and longevity pathways (e.g., through TET enzyme activation).

  • สุขภาพการเผาผลาญ: Exploring connections to glucose metabolism and general mobile vitality steadiness.

  • วิตามินทางการแพทย์: Utilized in specialised medical vitamin formulation.

  • การวิเคราะห์: Elementary software in biochemistry, cell biology, and metabolism research.

  • Cosmeceuticals (Rising): Early analysis into potential pores and skin barrier and collagen assist advantages.

10. Our Ironclad High quality Dedication (Past the COA)
High quality is not a division; it is our tradition. At Aiherba, our High quality Management (QC) system is constructed on:

  • cGMP Compliance: Adherence to present Good Manufacturing Practices is non-negotiable.

  • Superior Analytical Arsenal: We deploy HPLC/UPLC (purity, assay), GC-MS/MS & LC-MS/MS (residual solvents, pesticides), ICP-MS (heavy metals), FTIR/NMR (id affirmation), and rigorous microbiological testing suites.

  • Strict Uncooked Materials Management: Each enter materials is certified and examined.

  • In-Course of Checks: Actual-time monitoring all through fermentation and purification.

  • การวิจัยเสถียรภาพ: Ongoing applications to ensure shelf life.

  • การตรวจสอบย้อนกลับแบบเต็มรูปแบบ: From uncooked materials lot to completed product batch.

  • การปรับปรุงอย่างต่อเนื่อง: Common audits, technique validation, and workers coaching guarantee our techniques are all the time advancing. Our 20%+ increased purity customary is a direct results of this obsession.

11. Safe Supply: Packaging & World Logistics

  • บรรจุภัณฑ์: 1kg, 5kg sealed luggage (food-grade HDPE with aluminum liner), 25kg fiber drums (HDPE interior liner). Customized packaging out there for เป็นกลุ่ม คำสั่งซื้อ

  • พื้นที่จัดเก็บ: Retailer <25°C (77°F) in a dry place. Preserve containers tightly sealed.

  • อายุการเก็บรักษา: Sometimes 24 months from manufacturing date when saved appropriately.

  • โลจิสติกส์: Seamless international delivery through air or sea. Experience in dealing with customs clearance and documentation worldwide. Hazardous items compliant.

12. The Science & Way forward for AKG

  • การเจาะลึกกลไก: Analysis continues to unravel AKG’s roles past the Krebs cycle – as an epigenetic modulator (through TET enzymes & DNA demethylation), a regulator of mTOR signaling and autophagy, a precursor for neurotransmitters, and a key participant in collagen hydroxylation.

  • Business Innovation: Focus contains enhancing bioavailability (salts, esters, supply techniques), exploring novel well being functions (neurological, metabolic, age-related), and scaling ultra-pure manufacturing sustainably (like our fermentation tech).

  • Analysis Frontiers & Hurdles: Key areas embody establishing clear medical efficacy for particular situations, defining optimum dosing regimens, understanding long-term security profiles, and overcoming formulation challenges for numerous functions. Translating promising mobile results into tangible human advantages stays an energetic pursuit.

13. Your AKG Questions Answered (FAQ)

  • Q: What types of AKG do you provide? A: Primarily Alpha-Ketoglutarate Disodium Salt (excessive purity powder). Different types (e.g., Calcium) could also be out there – inquire.

  • Q: Can I purchase small portions for R&D? A: Completely! We provide samples and small-scale portions for analysis and formulation improvement.

  • Q: Do you provide bulk / wholesale pricing? A: Sure! Aggressive tiered pricing is on the market for bigger portions. Contact us for a quote.

  • Q: Are you the direct producer? A: Sure, we’re the supply โรงงานผลิต. Shaanxi Zhonghong (Aiherba) controls the whole R&D and manufacturing course of.

  • Q: What is the lead time for orders? A: Varies by amount. Samples ship rapidly. เป็นกลุ่ม manufacturing usually 2-4 weeks after order affirmation. We offer agency timelines.

  • Q: The place is your manufacturing facility situated? A: Our superior manufacturing amenities are in Shaanxi Province, China.

  • Q: How do I get a COA? A: A complete Certificates of Evaluation is supplied with แต่ละ cargo.

  • Q: Is your AKG appropriate for vegan merchandise? A: Sure, our fermentation-derived AKG is totally plant-free and appropriate for vegan formulations.

  • Q: Can I get a pattern? ก: Sure! Request your free AKG pattern as we speak! (See Part 14).

14. Get Your Premium AKG – Samples & Quotes!
Able to expertise the Aiherba distinction? Whether or not you want R&D samples or large-scale เป็นกลุ่ม provide for ขายส่ง, we’re your confirmed associate.

  • Purchase Now / Get a Quote: Go to our web site aiherba.com for detailed product information.

  • Request Your FREE AKG Pattern: Check our high quality firsthand. E mail our gross sales workforce.

  • Contact Us Instantly:

15. Conclusion: Elevate Your Merchandise with Aiherba AKG
Alpha-Ketoglutarate stands on the fascinating intersection of elementary metabolism and rising well being science. Sourcing the highest high quality AKG is paramount for analysis integrity and product efficacy. Aiherba, with our 28-year legacy, cutting-edge science, patented purification tech, and unwavering dedication to cGMP purity exceeding trade requirements by 20%, is your very best associate. We do not simply provide AKG; we ship the muse for innovation. From exact R&D samples to dependable เป็นกลุ่ม ขายส่ง portions, belief Aiherba – the โปรดิวเซอร์ behind premium bio-actives. Contact us as we speak to debate your wants and request your pattern!

 Alpha-Ketoglutarate, AKG, Provider, Producer, Manufacturing facility, Purchase, Bulk, Wholesale, Value, Extract, Purity, COA, High quality, Dietary Complement, Sports activities Vitamin, Fermentation, cGMP, Purchase AKG, AKG Powder, AKG Provider, AKG Producer, Bulk AKG, Wholesale AKG, AKG Value, AKG Manufacturing facility, Aiherba.

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