Silybin B Ingredient Supplier – Pharmaceutical-Grade Extract for Liver Support & Antioxidant Applications
1.Silybin B Powder | High-Purity Bulk Ingredient for Global Manufacturers
Silybin B is a highly purified flavonolignan isolated from Silybum marianum (milk thistle), widely used as a premium botanical active in nutraceuticals, functional foods, and research formulations. As a Silybin B bulk supplier, we provide consistent, specification-driven Silybin B powder manufactured under strict GMP and ISO quality systems. Each batch is produced with validated extraction and purification processes and supported by a complete Silybin B spec sheet, COA, and safety data sheet available upon request.
Designed for professional buyers, our Silybin B meets international compliance requirements and is suitable for large-scale production. Whether you are looking to buy Silybin B for supplement development, ingredient research, or contract manufacturing, this material delivers reliable purity, traceability, and batch-to-batch consistency—key factors for global sourcing and long-term supply partnerships.
2. Product Overview – What Is Silybin B
Silybin B is one of the two major diastereomers of silybin, the principal active component of the silymarin complex derived from milk thistle seeds. Compared with mixed silymarin extracts, isolated Silybin B offers:
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Defined chemical identity
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Higher formulation precision
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Easier standardization in finished products
Key identifiers
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English Name: Silybin B
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CAS No.: 22888-70-6
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Molecular Formula: C₂₅H₂₂O₁₀
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Molecular Weight: 482.44 g/mol
3. Product Source & Raw Material Traceability
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Botanical source: Silybum marianum seeds
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Origin: Verified contract-grown farms
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Traceability: Full lot tracking from raw seed intake to finished powder
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Sustainability: Controlled harvesting and supplier audits
Each production lot is traceable through documented sourcing, in-process controls, and finished product testing.
4. Benefits & Functional Properties (Non-Medical)
Silybin B is primarily valued for its antioxidant properties and role as a plant-derived bioactive compound. In commercial applications, it is commonly used as:
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A standardized botanical active
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A reference compound in research
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A functional ingredient supporting formulation stability
Statements above are for ingredient characterization only and are not intended to diagnose, treat, cure, or prevent any disease.
5. Traditional & Modern Context
Milk thistle extracts have been traditionally used in European herbal practices. Modern processing allows the isolation of specific fractions such as Silybin B, enabling manufacturers to work with well-defined compounds rather than variable whole extracts.
6. Recommended Use & Formulation Guidance
Typical use level (industry reference):
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Nutraceutical formulations: determined by formulation design and regulatory requirements
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Research applications: as specified by protocol
Best formulation practices:
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Compatible with capsules, tablets, and powder blends
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Often combined with phospholipids or complementary botanicals for formulation performance
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Suitable for dry, low-moisture systems
7. Scientific Source & Quality Assurance
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Production under ISO 9001, GMP, and HACCP systems
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In-house and third-party testing
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Analytical methods: HPLC, UV spectroscopy, microbial analysis
COA / MSDS available upon request.
8. Product Specifications (Typical)
| Item | Specification |
|---|---|
| Appearance | Yellowish-white to pale yellow powder |
| Assay | ≥ 98% (HPLC) |
| Solubility | Slightly soluble in water; soluble in ethanol |
| Odor | Characteristic |
| Loss on Drying | ≤ 5.0% |
| Ash | ≤ 1.0% |
9. COA – Safety & Quality Parameters
Pesticide Residues
| Parameter | Limit | Method |
|---|---|---|
| Organophosphates | Complies | GC-MS |
| Organochlorines | Complies | GC-MS |
| Pyrethroids | Complies | GC-MS |
Heavy Metals
| Parameter | Limit | Method |
|---|---|---|
| Lead (Pb) | ≤ 3 ppm | ICP-MS |
| Arsenic (As) | ≤ 2 ppm | ICP-MS |
| Cadmium (Cd) | ≤ 1 ppm | ICP-MS |
| Mercury (Hg) | ≤ 0.1 ppm | ICP-MS |
Microbiological Control
| Parameter | Limit | Method |
|---|---|---|
| Total Plate Count | ≤ 10³ CFU/g | USP |
| Yeast & Mold | ≤ 100 CFU/g | USP |
| E. coli | Negative | USP |
| Salmonella | Negative | USP |
10. Production Process
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Raw material inspection & authentication
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Controlled extraction (water–ethanol system)
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Concentration & purification
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Crystallization and drying
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Milling & blending
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Final QC testing (HPLC / Microbial)
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Packaging & batch release
11. Storage, Shelf Life & Packaging
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Storage: Cool, dry place, protected from light
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Shelf life: 24 months
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Packaging: 25 kg fiber drum with double PE liner
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Palletization: 27 drums per pallet
12. Sample Policy, MOQ & Logistics
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Samples: Available upon request
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MOQ: 1 kg
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Lead time: 3–7 working days
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Shipping: Air, sea, or express courier
13. Applicable Industries & Use Scenarios
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Dietary supplements
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Functional foods
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Botanical research
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Ingredient formulation development
14. About the Manufacturer
AIHerba® is the international brand of Shaanxi Zhonghong Investment Technology Co., Ltd., a GMP-certified natural plant extracts manufacturer with over 28 years of R&D and production experience. We supply high-purity botanical ingredients worldwide and support OEM & ODM projects with documented quality systems and traceable supply chains.
Contact:
📧 sales@aiherba.com | info@aiherba.com | liaodaohai@gmail.com
🌐 www.aiherba.com
15. FAQ
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What is the difference between Silybin B and Silybin A?
They are diastereomers with the same molecular formula but different spatial configurations. -
Is this product suitable for nutraceutical manufacturing?
Yes, it is produced under GMP with complete documentation. -
Do you provide a Silybin B COA and SDS?
Yes, both are available upon request. -
What is the typical Silybin B bulk price?
Pricing depends on quantity and specification—contact sales for a quote. -
Is third-party testing available?
Yes, independent laboratory reports can be provided. -
How do you ensure batch consistency?
Through standardized raw materials, validated processes, and full QC release testing.
16. References
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National Center for Biotechnology Information (PubMed): https://pubmed.ncbi.nlm.nih.gov
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National Institutes of Health (NIH): https://www.nih.gov
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U.S. Food & Drug Administration (FDA): https://www.fda.gov
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PubMed: “Silibinin and hepatoprotection” (PMID: 19700054)
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NIH Natural Medicines Database
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FDA Botanical Drug Development Guidance
17. Why Work With AIHerba® (Shaanxi Zhonghong)
Expertise
28+ years of professional extraction, formulation, and OEM/ODM development.
Authoritativeness
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GMP-certified production
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ISO, HACCP, and third-party laboratory testing
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Traceable supply chain & batch-level documentation
Trustworthiness
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Real factory photos and manufacturing videos available
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Strict QC from raw material to finished products
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Transparent price, COA, and sample support
18. Contact & Verification
AIHerba® – Shaanxi Zhonghong Investment Technology Co., Ltd.
📧 sales@aiherba.com | info@aiherba.com | liaodaohai@gmail.com
🌐 www.aiherba.com
GMP certified plant extract for cosmetics, functional foods, and dietary supplements.
