1. Tetrahydro Piperine – High-Purity Bulk Powder Supplier | AIHerba®
AIHerba® offers high-purity Tetrahydro Piperine in bulk powder form, a premium botanical extract derived from black pepper (Piper nigrum) through advanced extraction techniques. Our GMP-certified factory in China ensures consistent quality, traceable supply chains, and compliance with international testing standards (COA, heavy metals, pesticides, and microbial limits). Ideal for cosmetic formulations, functional foods, dietary supplements, and pharmaceutical applications, Tetrahydro Piperine enhances the bioavailability of active ingredients and provides a reliable natural solution for global manufacturers. With over 28 years of R&D and production expertise, AIHerba supports customized formulations, rapid delivery, and OEM/ODM services to meet professional sourcing requirements.
2. Product Overview
Product Name: Tetrahydro Piperine
Synonyms: Cosmoperine, Dihydro Piperine
CAS Number: 23434‑88‑0
Molecular Formula: C₁₇H₂₁NO₃
Appearance: Yellowish-white powder with mild pepper aroma
Purity: ≥ 98% (HPLC)
Solubility: Soluble in ethanol, DMSO; slightly soluble in water
MOQ: 1 kg
Packaging: 25 kg/drum or customized
3. Product Source & Production Origin
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Botanical Source: Piper nigrum (Black Pepper)
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Extraction Method: Supercritical CO₂ extraction & ethanol-water extraction
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Location: Shaanxi, China (AIHerba GMP-certified facility)
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Supply Chain Traceability: Raw material → Extraction → QC → Packaging → Shipment
4. Mechanism & Benefits
Tetrahydro Piperine functions as a bioavailability enhancer by interacting with metabolic enzymes, improving absorption and stability of co-administered botanical or active compounds. Benefits include:
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Enhanced nutrient absorption in functional foods and nutraceuticals
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Stability improvement for sensitive cosmetic and dietary ingredients
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Reliable natural botanical source for research and formulation
⚠ Note: Not intended as a medical treatment or therapeutic product
5. Traditional Applications & Usage Guidelines
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Traditional Use: Derived from black pepper, traditionally used as a bioenhancer in botanical formulations
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Recommended Dosage for Industry Applications: 0.5–2% in formulations (depending on final product)
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Best Formulation Practices: Pair with curcumin, resveratrol, or other poorly absorbed botanicals to enhance efficacy in dietary supplements or functional foods
6. Product Specification & Testing Table COA
6.1 Residual Pesticide Testing
| No. | Pesticide Name | Limit (ppm) | Test Method |
|---|---|---|---|
| 1 | Aldrin | ND | GC-MS |
| 2 | Dieldrin | ND | GC-MS |
| 3 | Endrin | ND | GC-MS |
| 4 | Heptachlor | ND | GC-MS |
6.2 Heavy Metals
| No. | Metal | Limit (ppm) | Test Method |
|---|---|---|---|
| 1 | Lead (Pb) | ≤ 1.0 | ICP-MS |
| 2 | Arsenic (As) | ≤ 1.0 | ICP-MS |
| 3 | Cadmium (Cd) | ≤ 0.5 | ICP-MS |
| 4 | Mercury (Hg) | ≤ 0.1 | ICP-MS |
6.3 Microbiological Testing
| No. | Parameter | Limit | Test Method |
|---|---|---|---|
| 1 | Total Plate Count | ≤ 1000 CFU/g | AOAC 990.12 |
| 2 | Yeast & Mold | ≤ 100 CFU/g | AOAC 997.02 |
| 3 | E. coli | ND | AOAC 991.14 |
| 4 | Salmonella | ND | AOAC 2004.03 |
7. Production Process
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Raw Material Selection: GMP-compliant black pepper sourced from controlled farms
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Extraction: Supercritical CO₂ & ethanol-water extraction
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Filtration & Concentration: Purification via chromatography
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Drying: Low-temperature vacuum drying to retain potency
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Quality Control: COA, residual solvent, heavy metal, microbial testing
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Packaging: Moisture-proof drums or customized OEM packaging
8. Storage & Shelf Life
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Storage Conditions: Cool, dry, away from direct sunlight
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Shelf Life: 24 months in original sealed packaging
9. Packaging & Sample Policy
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Standard Packaging: 25 kg/drum, 27 drums/pallet
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Sample Availability: 10–50 g samples for testing available upon request
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MOQ: 1 kg for bulk orders
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Shipping: Air, sea, or express; all products compliant with international shipping regulations
10. Clinical Data & Latest Research
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Bioenhancer function validated in multiple studies:
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Widely cited in functional food, nutraceutical, and cosmetic formulations
11. Industry Applications
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Dietary Supplements: Bioavailability enhancers, functional blends
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Cosmetics: Anti-aging, nutrient stabilization
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Pharmaceuticals: Active compound formulation support
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Food & Beverage: Functional beverages, nutraceutical fortification
12. Usage Methods
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Dissolve in ethanol or formulation-compatible solvent
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Recommended blending ratio: 0.5–2% of total formula depending on target application
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Compatible with other botanical extracts and active ingredients
13. Authority & Quality Assurance
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Certifications: GMP, ISO, Halal, Kosher (on request)
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Testing Reports: COA, SDS, heavy metals, microbial limits available
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Factory Experience: 28+ years of extraction R&D and production
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Brand Trust: AIHerba® is a leading Chinese botanical extract OEM supplier
14. FAQ (6 Key Questions)
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Q: What is Tetrahydro Piperine used for?
A: It is primarily used as a bioavailability enhancer in dietary supplements, functional foods, and cosmetic formulations. -
Q: What purity levels are available?
A: ≥ 98% HPLC; custom purity available on request. -
Q: Can you provide COA and SDS?
A: Yes, all bulk orders come with full COA and SDS documentation. -
Q: What is the minimum order quantity (MOQ)?
A: Standard MOQ is 1 kg; samples are available from 10 g. -
Q: How should it be stored?
A: Keep sealed in a cool, dry place away from sunlight; shelf life is 24 months. -
Q: Is it suitable for OEM formulations?
A: Yes, AIHerba provides OEM/ODM services including custom packaging and formulation guidance.
15. References & Regulations
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PubMed: Tetrahydro Piperine Studies
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European Pharmacopoeia: Piperine / Tetrahydro Piperine standards
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ISO 9001 / GMP compliance documents
16. Contact & Brand Information
AIHerba® | China Natural Plant Extracts Supplier & OEM Factory
Company: Shaanxi Zhonghong Investment Technology Co., Ltd.
Email: sales@aiherba.com | info@aiherba.com | liaodaohai@gmail.com
Website: www.aiherba.com
Factory Advantage: GMP-certified, 28+ years of production expertise, modern extraction technology, complete traceability, global shipping, professional B2B support.





