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Paeonol

Paeonol supplier bulk factory Wholesale Extract factory

  1. English Name: Paeonol
  1. Specification
    • Normal Powder: Paeonol ≥ 99% (HPLC)
    • Water-soluble Type: Paeonol ≥ 95% (HPLC), enhanced solubility through cyclodextrin inclusion or nanoemulsion expertise, solubility as much as 5 mg/mL in water
  1. Appearance
    • Powder: White to off-white crystalline powder, with a attribute minty odor
    • Water-soluble Type: Off-white to gentle yellow free-flowing powder
  1. CAS NO.:552-41-0
  1. Lead time: 3 – 7 Working Days
  1. Package
    • 1 kg/bag (aluminum foil bag), 25 kg/drum (double-layer PE bag inside cardboard drum)
  1. Main Market: Asia (China, Japan, Korea), North America, Europe
  1. Application Scenarios

Core Properties

  • Molecular Method: C₉H₁₀O₃
  • Solubility: Sparingly soluble in water; soluble in ethanol, ether, and chloroform. Water-soluble modifications enhance its usability in aqueous methods.
  • Key Options
    • Anti-inflammatory: Inhibits the manufacturing of pro-inflammatory cytokines, decreasing tissue swelling and ache.
    • Antioxidant: Scavenges free radicals, defending cells from oxidative harm.
    • Analgesic: Supplies pain-relieving results, similar to some non-steroidal anti-inflammatory medicine.
    • Antimicrobial: Displays inhibitory exercise towards varied micro organism and fungi.

Application Scenarios

1. Prescription drugs

  • Oral Drugs:
    • Utilized in tablets and capsules for treating rheumatoid arthritis, osteoarthritis, and different inflammatory circumstances. It helps alleviate joint ache and swelling.
  • Topical Preparations:
    • Included into lotions, gels, and ointments for relieving pores and skin itching, eczema, and sunburn. Its anti-inflammatory and antipruritic properties soothe irritated pores and skin.
  • Injectable Formulations:
    • Investigated in medical trials for intravenous use in extreme inflammatory ailments, the place speedy systemic motion is required.

2. Cosmetics & Private Care

  • Anti-aging Merchandise:
    • Added to serums and moisturizers to fight oxidative stress, scale back the looks of positive strains, and promote pores and skin elasticity.
  • Anti-acne and Soothing Skincare:
    • Inhibits the expansion of acne-causing micro organism and reduces irritation in pimples therapies. Additionally utilized in merchandise for delicate pores and skin to calm redness and irritation.
  • Hair Care:
    • Included in shampoos and hair conditioners to assuage the scalp, deal with dandruff, and promote a wholesome scalp atmosphere.

3. Animal Well being

  • Veterinary Drugs:
    • Utilized in livestock and pets for ache reduction and anti inflammatory functions, comparable to treating musculoskeletal issues in horses or arthritis in canine.
    • Added to animal feed as an antioxidant to enhance the standard of meat, milk, and eggs by decreasing lipid oxidation.

4. Practical Meals & Drinks

  • Nutraceuticals:
    • Included into dietary dietary supplements within the type of capsules or softgels, marketed for its anti-inflammatory and antioxidant well being advantages.
  • Beverage Components:
    • Added to useful drinks at low concentrations (0.1 – 0.5%) to offer potential well beingselling properties, particularly in merchandise concentrating on lively existence or stress reduction.

Detection Strategies

  • ExcessiveEfficiency Liquid Chromatography (HPLC):
    • Column: C18 (250 × 4.6 mm, 5 μm), Cellular Part: Methanol – water (60:40 v/v), Stream Fee: 1.0 mL/min, Detection Wavelength: 274 nm, used for correct quantification of paeonol content material.
  • Gasoline Chromatography-Mass Spectrometry (GC-MS):
    • Confirms the molecular construction and purity, particularly helpful for detecting hint impurities or in advanced matrices.
  • Fourier Remodel Infrared Spectroscopy (FTIR):
    • Identifies attribute useful teams of paeonol (comparable to hydroxyl and carbonyl teams) to confirm product identification.

Supply & Benefits

  • Natural Supply: Extracted from the basis bark of Paeonia suffruticosa (tree peony) and Paeonia lactiflora (Chinese language peony), conventional medicinal crops in Chinese language natural medication.
  • Multi-functional: Its numerous bioactivities make it appropriate for varied purposes from medication to client merchandise.
  • Conventional Use Validation: With a protracted historical past of use in conventional medication, it gives a dependable basis for contemporary purposes.

Regulatory Compliance

  • China NMPA: Accredited as a pharmaceutical ingredient and utilized in many Chinese language patent medicines.
  • US FDA: Regulated as a dietary ingredient when utilized in dietary supplements, topic to Good Manufacturing Observe (GMP) necessities.
  • EU Beauty Regulation: Allowed as a beauty ingredient, with restrictions on most focus in several product sorts.

Paeonol: Premium Manufacturer & World Supplier for Beauty and Nutraceutical Industries | Aiherba

 Supply high-purity Paeonol from Zhonghong, a number one producer and bulk supplier. Discover its advantages for cosmetics, dietary supplements & prescription drugs. Request a free pattern for R&D and get a aggressive value quote.


1. What is Paeonol?

Paeonol is a potent bioactive compound naturally discovered within the root bark of the Chinese language tree Paeonia suffruticosa (Peony) and the herb Cynanchum paniculatum. This phenolic compound is the important thing marker ingredient accountable for the famend therapeutic results in conventional drugs. As a flexible energetic, it is more and more wanted by B2B formulators within the beauty, nutraceutical, and pharmaceutical sectors for its distinctive anti-inflammatory and antioxidant properties. Sourcing from a dependable Paeonol producer is essential for making certain consistency and efficacy in your finish merchandise.

2. Supply, Chemical Properties, and Identifiers

  • Product Supply: Primarily extracted from the foundation bark of Paeonia suffruticosa Andrews.

  • Main Energetic Compound: Paeonol (2′-Hydroxy-4′-methoxyacetophenone).

  • CAS Quantity: 552-41-0

  • Molecular Method (MF): C9H10O3

  • Molecular Weight (MW): 166.17 g/mol

  • EINECS: 209-004-6

3. What Defines the Finest Paeonol? A B2B Purchaser’s Information

For worldwide manufacturers and exporters, deciding on a high-grade Paeonol is paramount. The very best product is outlined by its purity, standardization, and the technical assist supplied by the supplier.

  • Key Ingredient & Efficacy: The best Paeonol is standardized to a excessive purity degree (e.g., 98%+). Its scientifically supported advantages embrace:

    • Highly effective Anti-Inflammatory Motion: Modulates key inflammatory pathways (e.g., NF-κB), making it very best for soothing skincare and joint well being formulations.

    • Antioxidant Exercise: Scavenges free radicals, defending cells from oxidative stress and supporting anti-aging product efficacy.

    • Analgesic (Ache-Relieving) Results: A standard use supported by trendy analysis for topical ache aid purposes.

    • Cardiovascular and Neuroprotective Potential: Rising analysis signifies advantages for blood circulation and cognitive well being.

    • (Compliant to be used in beauty substances, dietary dietary supplements, and pharmaceutical purposes.)

  • Origin & High quality: Our Paeonol is sourced from premium, cultivated Paeonia suffruticosa, making certain traceability and constant high quality batch-to-batch.

  • Utilization & Dosage:

    • Typical Use: Included into skincare serums, lotions, capsules, tablets, and topical gels.

    • Beneficial Dosage: Dosage varies by software. Frequent utilization ranges are 0.1-1.0% in cosmetics and 50-200mg per day in dietary supplements. Our technical crew gives particular personalized natural extract steerage on your formulations.

  • Relevant Viewers: Formulators growing anti-aging cosmetics, topical ache aid merchandise, anti-inflammatory dietary supplements, and purposeful meals.

  • Notes & Aspect Results:

    • Precautions: Typically thought-about secure. As with all energetic, patch testing for topical use is suggested. Not really helpful to be used throughout being pregnant or lactation with out skilled session.

    • Aspect Results: Uncommon at really helpful doses. Excessive doses might trigger delicate gastrointestinal discomfort.

4. Why Associate with Zhonghong (Aiherba) as Your Paeonol Manufacturer?

Shaanxi Zhonghong Investment Technology Co., Ltd. (World Advertising: Aiherba) is a licensed high-tech enterprise and a trusted exporter specializing within the analysis, growth, and bulk manufacturing of premium plant extracts. We serve B2B shoppers globally with a give attention to innovation and reliability.

  • Scientific Excellence: We preserve strategic joint laboratories with 5 main universities, maintain over 20 patents, and handle a proprietary world compound library for steady innovation.

  • Unmatched High quality Management: Our funding in superior tools like HPLC and Superconducting NMR ensures our Paeonol purity requirements exceed typical business specs by over 20%.

  • World B2B Community: With 28 years of expertise in bioactive compounds, we provide personalized substances to multinational firms, wholesale distributors, and analysis establishments throughout 80+ international locations in Asia, Europe, and the Americas.

  • Finish-to-Finish Help: We offer extra than simply product; we provide complete technical dossiers, regulatory assist, and personalized natural extract options on your particular software.

5. Detailed Product Specs (COA)

Each batch is accompanied by a complete Certificates of Evaluation (COA) to ensure it meets your stringent specs.

Class Merchandise Name Specification Check Technique
Pesticide Residues Chlorpyrifos ≤0.2 mg/kg GC-MS
Cypermethrin ≤0.5 mg/kg GC-MS
Dichlorvos ≤0.1 mg/kg GC-MS
Heavy Metals Lead (Pb) ≤3.0 mg/kg ICP-MS
Arsenic (As) ≤2.0 mg/kg ICP-MS
Cadmium (Cd) ≤1.0 mg/kg ICP-MS
Mercury (Hg) ≤0.1 mg/kg ICP-MS
Microbiology Complete Plate Rely ≤1000 CFU/g USP <61>
Yeast & Mould ≤100 CFU/g USP <61>
E. Coli Damaging USP <62>
Salmonella Damaging USP <62>
Assay Paeonol Content ≥98.0% HPLC

6. Manufacturing Course of & High quality Management

Our manufacturing begins with sustainably sourced uncooked materials. We make use of superior extraction strategies, together with low-temperature solvent extraction and trendy chromatographic purification strategies, to isolate Paeonol effectively whereas preserving its bioactivity.

Our High quality Management is built-in into each step. It begins with uncooked materials authentication and continues with in-process testing throughout extraction and purification. Last product evaluation utilizing Excessive-Efficiency Liquid Chromatography (HPLC) ensures exact standardization of the Paeonol content material. We make use of Fuel Chromatography-Mass Spectrometry (GC-MS) for residual solvent evaluation and ICP-MS for heavy steel detection. This multi-tiered QC protocol, managed in our ISO-certified amenities, ensures each gram of our Paeonol meets the best requirements of security, efficiency, and consistency required by world manufacturers.

7. Application Scenarios

Paeonol is a flexible ingredient for varied industries:

  • Cosmeceuticals: Key energetic in anti-aging lotions, delicate pores and skin soothing lotions, whitening serums, and pimples therapy merchandise.

  • Nutraceuticals & Dietary Dietary supplements: Utilized in capsules and tablets for joint well being, inflammatory assist, and total wellness.

  • Prescribed drugs: Investigated and used as an energetic ingredient in topical analgesics and anti inflammatory ointments.

  • Purposeful Meals & Drinks: Potential software in health-focused foods and drinks merchandise.

8. Well being Benefits, Analysis, and Innovation

The core mechanism of Paeonol is its potent inhibition of inflammatory mediators and its free-radical quenching capability. Present analysis is exploring its potential in mitigating metabolic syndrome and its neuroprotective results. The first business problem includes enhancing its bioavailability for oral purposes. At Zhonghong, our R&D focus is on growing novel supply programs, resembling phospholipid complexes or nanoemulsions, to beat this barrier and supply our B2B companions with next-generation, extremely efficient personalized substances.

9. FAQ – Continuously Requested Questions

Q: What is the standard MOQ for bulk orders?
A: Minimal Order Portions range based mostly on the precise product and customization. Contact us instantly to debate your wants, and we are going to present a tailor-made answer.

Q: Do you supply customized extraction and purification companies?
A: Sure, we specialise in personalized natural extract options. We are able to tailor the extraction course of, purity degree, and particle dimension to your particular formulation necessities.

Q: Can we request a pattern for our R&D and high quality testing?
A: Completely. We encourage it. We provide a free pattern natural extract program for certified companies and analysis establishments to guage our product high quality.

Q: What packaging choices do you supply for worldwide export?
A: We use sealed, double-layer plastic baggage inside foil-lined cardboard drums to make sure stability throughout transit. Smaller portions can be found in sealed foil baggage.

Q: What documentation do you present for worldwide delivery?
A: We offer all essential documentation, together with Certificates of Evaluation (COA), Certificates of Origin, Invoice of Lading, and business bill, making certain easy customs clearance.

10. The place to Purchase and Request Free Samples

As a number one producer and world supplier, we’re able to assist your provide chain with high-quality, bulk Paeonol.

Contact us at present to debate your procurement course of, request a free pattern, and get a aggressive wholesale value.

11. Conclusion

For B2B shoppers within the beauty, nutraceutical, and pharmaceutical industries, Paeonol presents a robust, pure energetic with compelling scientific backing. Selecting a supplier with sturdy R&D, rigorous QC, and confirmed worldwide export capabilities is vital. Zhonghong (Aiherba) gives not only a product, however a dependable partnership grounded in 28 years of experience, making certain you obtain a premium ingredient that meets your most demanding specs.

12. References

  • Journal of Ethnopharmacology: Research on the anti-inflammatory and analgesic results of Paeonol.

  • Phytomedicine: Analysis on the antioxidant mechanisms of Paeonol.

  • Worldwide Journal of Pharmaceutics: Investigations into novel supply programs for improved bioavailability of phenolic compounds.

  • USP-NF Compendial Strategies for Dietary Complement and Ingredient Testing.

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