Paeonol: The Multifunctional Bioactive Compound with Diverse Health Benefits

1. What is Paeonol?

Paeonol is a phenolic compound renowned for its extensive pharmacological activities. As a key bioactive ingredient, it has been used for centuries in Traditional Chinese Medicine (TCM) for its anti – inflammatory, analgesic, and antioxidant properties. Derived primarily from the roots of Paeonia suffruticosa Andr. (tree peony) and Paeonia lactiflora Pall. (Chinese peony), paeonol has gained significant attention in modern scientific research for its potential applications in treating various diseases and promoting overall health.

2. Product Origin and Chemical Properties

2.1 Source

Paeonol is mainly extracted from the dried roots of Paeonia suffruticosa and Paeonia lactiflora. These plants are cultivated in regions with suitable climates, such as Anhui, Sichuan, and Zhejiang in China. At Shaanxi Zhonghong Investment Technology Co., Ltd., we source high – quality peony roots from certified cultivation bases, ensuring the raw materials meet strict quality standards for optimal paeonol extraction.

2.2 Chemical Profile

3. Optimal Product, Health Benefits, Dosage, Precautions and Side Effects

3.1 Best Products and Content

The highest – quality paeonol products typically feature a purity of 98% or higher. Our company employs advanced extraction and purification technologies, including supercritical fluid extraction and high – performance liquid chromatography (HPLC), to achieve a purity level 20% above the industry average. This ensures maximum bioactivity and reliability for various applications.

3.2 Health Benefits

3.2.1 Anti – Inflammatory and Analgesic Effects

Paeonol inhibits the production of pro – inflammatory cytokines (such as TNF – α and IL – 6) and blocks the activation of inflammatory signaling pathways. This makes it effective in reducing inflammation and alleviating pain, applicable for conditions like arthritis, headache, and menstrual cramps.

3.2.2 Antioxidant Defense

It acts as a potent antioxidant by scavenging free radicals, including hydroxyl and superoxide radicals. Paeonol can enhance the activity of antioxidant enzymes like superoxide dismutase (SOD) and catalase, protecting cells from oxidative damage associated with aging, cardiovascular diseases, and neurodegenerative disorders.

3.2.3 Anti – Allergic and Anti – Asthmatic Properties

Paeonol suppresses the release of histamine and other allergic mediators, relieving allergic symptoms. It also relaxes bronchial smooth muscles, making it beneficial for managing asthma and allergic rhinitis.

3.2.4 Skin Health Improvement

In topical applications, paeonol can soothe irritated skin, reduce redness, and promote wound healing. Its anti – inflammatory and antioxidant effects help protect the skin from environmental damage and improve skin texture.

3.3 Recommended Dosage

In traditional Chinese medicine, the daily dosage of paeonol from herbal decoctions is usually 6 – 12 grams. For purified paeonol supplements, clinical studies often use doses ranging from 50 – 200 mg per day. However, individual dosages should be determined under the guidance of a healthcare professional.

3.4 Precautions and Side Effects

Paeonol is generally well – tolerated, but some individuals may experience mild gastrointestinal discomfort, such as nausea or diarrhea. It may also interact with certain medications, including anticoagulants and anti – epileptic drugs. Pregnant or nursing women, individuals with liver or kidney disorders, and those with known allergies to peony plants should avoid use or consult a doctor before consumption.

4. Company Introduction

With 28 years of experience in the bioactive compound industry, Shaanxi Zhonghong Investment Technology Co., Ltd. is a leading high – tech enterprise. Our operations span agile research and development, collaborative innovation, integrated manufacturing, and global marketing, serving the chemical, materials, and life science sectors.

5. Product Specifications

Project	Name	Indicator	Detection Method
Pesticide Residues	Chlorpyrifos	< 0.01 ppm	Gas Chromatography – Mass Spectrometry (GC – MS)
	Cypermethrin	< 0.02 ppm	GC – MS
	Carbendazim	< 0.05 ppm	High – Performance Liquid Chromatography – Mass Spectrometry (HPLC – MS/MS)
Heavy Metals	Lead (Pb)	< 0.5 ppm	Inductively Coupled Plasma – Mass Spectrometry (ICP – MS)
	Mercury (Hg)	< 0.01 ppm	Cold Vapor Atomic Absorption Spectroscopy (CVAAS)
	Cadmium (Cd)	< 0.05 ppm	ICP – MS
Microbial Contamination	Total viable count	< 100 CFU/g	Standard microbiological plating techniques
	Escherichia coli	Absent	Polymerase Chain Reaction (PCR) and plating
	Salmonella	Absent	PCR and plating
	Listeria monocytogenes	Absent	PCR and plating

6. Production Process

7. Application Scenarios

7.1 Pharmaceuticals

7.2 Nutraceuticals

7.3 Cosmetics

8. Quality Control

Quality control is the cornerstone of our paeonol production. At the raw material stage, we use DNA fingerprinting to authenticate the peony species and near – infrared spectroscopy to rapidly assess the quality and active ingredient content of the roots. During extraction, real – time monitoring of temperature, pressure, and solvent – to – raw material ratio ensures consistent extraction efficiency. In the purification process, HPLC is employed for precise separation and purity analysis, with each purification step closely monitored. After production, the final product undergoes comprehensive testing, including determining chemical purity, detecting pesticide residues and heavy metals using advanced analytical instruments, and performing microbial safety checks. Our quality control laboratory adheres to strict international standards, holding certifications like ISO 9001 for quality management and Good Manufacturing Practice (GMP). This multi – step, meticulous quality control system guarantees that every batch of paeonol meets the highest quality and safety benchmarks, providing reliable products to our global customers.

9. Packaging and Logistics

10. Health Efficacy Research, Industrial Application Innovation, and Challenges

10.1 Research Frontiers

10.2 Challenges

11. FAQ

11.1 Where can I buy Paeonol?

11.2 Is Paeonol safe for long – term use?

Paeonol is generally safe for long – term use when taken within recommended dosages. However, it is advisable to consult a healthcare professional, especially if you have underlying health conditions or are taking other medications.

11.3 Can Paeonol be used in cosmetics?

Yes, due to its anti – inflammatory and antioxidant properties, paeonol is widely used in cosmetics to soothe and protect the skin.

11.4 Does Paeonol interact with other medications?

Paeonol may interact with certain medications, such as anticoagulants and anti – epileptic drugs. It is important to inform your doctor about all the medications you are taking before using paeonol supplements.

12. Conclusion

Paeonol, a remarkable bioactive compound from traditional Chinese medicine, offers a wide range of health benefits and diverse applications. As a leading provider in the industry, Shaanxi Zhonghong Investment Technology Co., Ltd. is committed to delivering high – quality paeonol products, backed by advanced technology, strict quality control, and extensive global reach. Whether for pharmaceutical research, nutraceutical development, or cosmetic innovation, our paeonol offerings provide reliable solutions for enhancing human health and well – being.

13. References