쿠쿠르비타신

Cucurbitacin: Premium Manufacturer & World Supplier for Pharmaceutical and Analysis Functions | Aiherba

 Supply high-purity Cucurbitacin from Zhonghong, a number one 생산자 그리고 대량 공급업체. Discover its analysis purposes, advantages, and request a 무료 패턴 to your R&D initiatives. Get a aggressive 가치 quote immediately.

1. What is Cucurbitacin?

Cucurbitacin is a category of extremely oxidized tetracyclic triterpenoids discovered primarily in vegetation of the Cucurbitaceae household, resembling pumpkins, gourds, and cucumbers. These compounds are famend for his or her intensely bitter style and important organic exercise. For B2B purchasers within the pharmaceutical and analysis sectors, Cucurbitacins (notably Cucurbitacin B, E, and I) characterize a high-value, potent lively ingredient for anti-cancer, anti-inflammatory, and different therapeutic analysis purposes. Partnering with a dependable Cucurbitacin producer is important for acquiring materials of constant purity and validated organic exercise.

2. 공급, 화학적 특성 및 식별자

• 제품 공급: Extracted from varied Cucurbitaceae vegetation, with particular isoforms (e.g., Cucurbitacin B) typically sourced from Ecballium elaterium (Squirting Cucumber) or Citrullus colocynthis.

• Main Lively Compounds: Cucurbitacin B, Cucurbitacin E, Cucurbitacin I, amongst others.

• Instance CAS Quantity: 6199-67-3 (Cucurbitacin B)

• Instance Molecular System (MF): C32H46O8 (Cucurbitacin B)

• Instance Molecular Weight (MW): 558.71 g/mol (Cucurbitacin B)

• EINECS: Varies by particular Cucurbitacin sort.

3. Deciding on the Greatest Cucurbitacin: A Information for B2B Consumers and Researchers

을 위한 세계적인 pharmaceutical corporations, analysis establishments, and 수출업체, the definition of “finest” hinges on exact standardization, verified organic exercise, and complete analytical documentation.

• 주요 성분 및 효능: The very best grade Cucurbitacin is standardized to a selected isoform (e.g., 98%+ Cucurbitacin B). Its most researched properties embrace:

  • Potent Anti-Most cancers Exercise: Induces apoptosis and inhibits proliferation in varied most cancers cell traces by focusing on JAK-STAT3 and different signaling pathways. Observe: For analysis use solely; not for direct human consumption as a complement.

  • Sturdy Anti-Inflammatory and Immunosuppressive Results: Modulates inflammatory responses, making it a compound of curiosity for autoimmune illness analysis.

  • Purported Hepatoprotective Properties: Some isoforms are studied for his or her potential to guard liver cells.

  • (Compliant for analysis purposes, pharmaceutical intermediate use, and reference requirements.)

• 원산지 및 고품질: Our uncooked supplies are sourced from recognized botanical species and cultivated beneath managed situations to make sure a constant chemical profile.

• 활용 및 복용량:

  • 일반적인 사용: Predominantly utilized in pharmaceutical R&D as a reference commonplace, a constructing block for novel drug synthesis, and for in vitro and in vivo (animal mannequin) research. Not usually utilized in cosmetics or dietary dietary supplements on account of its efficiency and potential toxicity.

  • Advisable Dosage: There isn’t any commonplace every day consumption for people. All dosing is very particular to analysis protocols. Our group supplies technical knowledge to tell your experimental design.

• 관련 시청자: Pharmaceutical R&D departments, educational analysis establishments, and biotechnology corporations engaged in oncology and immunology analysis.

• 참고사항 및 측면 결과:

  • 지침: HANDLE WITH CARE. Cucurbitacins are extremely bioactive and might be poisonous if mishandled. They’re for analysis functions solely by certified professionals in laboratory settings. Not for meals, beauty, or complement use.

  • 측면 결과: Primarily based on analysis, excessive doses may cause extreme gastrointestinal misery and different systemic toxicities.

4. Why Associate with Zhonghong (Aiherba) as Your Cucurbitacin Manufacturer?

산시 중홍 투자기술 유한회사(세계광고: 아이허바) 허가받은 첨단기술 기업이며 신뢰받는 수출업체 specializing within the synthesis, extraction, and purification of high-potency bioactive compounds for the worldwide B2B 시장.

• 과학적 우수성: Our joint laboratories with 5 main universities and portfolio of 20+ patents enable us to deal with advanced purification challenges, providing Cucurbitacins of outstanding purity.

• 비교할 수 없는 고품질 관리: Our funding in superior tools like HPLC and Superconducting NMR ensures our Cucurbitacin purity requirements exceed typical business specs, which is vital for reproducible analysis outcomes.

• 세계 B2B 커뮤니티: 28년의 전문성을 바탕으로 개인화된 elements and reference requirements to multinational pharmaceutical firms, 모조리 distributors, and premier analysis establishments throughout 80+ nations.

• 기술 지원: We offer complete supporting documentation, together with detailed MSDS and analytical knowledge sheets, important to your regulatory and analysis compliance.

5. 상세 제품 사양(COA)

Each batch is accompanied by a complete Certificates of Evaluation (COA) to ensure it meets rigorous research-grade requirements.

6. 제조과정 및 품질관리

The extraction of Cucurbitacin requires refined strategies on account of its advanced construction and low pure abundance. We make use of superior strategies, together with chromatographic separation and crystallization, to isolate particular Cucurbitacin isoforms from rigorously chosen plant materials.

우리의 고품질 관리 protocol is designed for research-grade actives. It begins with botanical authentication and is adopted by in-process testing at each vital step of the extraction and purification course of. Ultimate product evaluation utilizing Excessive-Efficiency Liquid Chromatography (HPLC) and Liquid Chromatography-Mass Spectrometry (LC-MS) ensures exact standardization and confirms the molecular id of the compound. This multi-layered QC course of, performed in our state-of-the-art labs, ensures each batch delivers constant, dependable efficiency in your most delicate analysis purposes, making us a premier 개인화된 천연 추출물 accomplice for the pharmaceutical business.

7. 응용 프로그램 시나리오

Cucurbitacin is primarily utilized in superior analysis settings:

• 제약 R&D: As a lead compound in oncology drug discovery, a reference commonplace, and for mechanistic research on apoptosis.

• 튜토리얼 분석: Utilized in cell biology and pharmacology departments to review cell signaling pathways (JAK/STAT, NF-κB) and inflammatory processes.

• 생명공학: Investigated for growing focused most cancers therapies and novel anti-inflammatory brokers.

8. Analysis, Innovation, and Challenges

The first mechanism of Cucurbitacin B entails the inhibition of the JAK/STAT3 pathway, resulting in cell cycle arrest and apoptosis in most cancers cells. Present 분석 프런티어 concentrate on bettering its bioavailability and lowering systemic toxicity via novel drug supply techniques (e.g., nanoparticle encapsulation, conjugation). The principle 문제 is translating its potent in vitro exercise into protected and efficient scientific therapies. At Zhonghong, our 혁신 lies in growing extremely purified isoforms and supporting our B2B companions by offering the vital high-quality uncooked supplies wanted for his or her next-generation drug growth applications.

9. FAQ – 꾸준히 요청되는 질문

Q: What is the Minimal Order Amount (MOQ) for analysis functions?
A: MOQs range primarily based on the precise Cucurbitacin isoform and purity. We accommodate orders for research-scale portions. Contact us to debate your particular wants.

Q: Are you able to present customized purification to isolate a selected Cucurbitacin isoform?
A: 물론입니다. 우리는 다음에 집중합니다. 개인화된 천연 추출물 options. Our superior know-how permits us to tailor our processes to isolate and purify particular isoforms per your analysis necessities.

Q: Do you provide samples for technique growth and validation?
A: 물론입니다. 무료 패턴 천연 추출물 supplies to certified analysis establishments and firms for analysis and testing functions.

Q: What packaging do you employ to make sure product stability throughout worldwide transport?
A: We use sealed, tamper-evident containers with desiccant to guard the product from moisture and contamination, making certain it arrives in optimum situation to your analysis.

Q: What documentation is supplied with worldwide orders?
A: We offer a full suite of paperwork together with Certificates of Evaluation (COA), Materials Security Knowledge Sheet (MSDS), Certificates of Origin, and industrial bill.

10. 무료 샘플 구매 및 신청 장소

1위로서 생산자 그리고 국제 공급업체 of high-potency plant extracts, we’re your trusted accomplice for sourcing research-grade Cucurbitacin.

귀하의 조달 요구 사항을 논의하고, R&D에 대한 무료 패턴을 요청하고, 경쟁력 있는 도매 가격을 얻으려면 지금 바로 저희에게 연락하세요.

• 이메일: sales@aiherba.com / liaodaohai@gmail.com

• 웹사이트: www.aiherba.com

11. 결론

을 위한 B2B purchasers in pharmaceutical and superior analysis, Cucurbitacin represents a robust instrument for drug discovery and organic mechanism research. Deciding on a supplier with rigorous purification capabilities, analytical experience, and a deep understanding of compliance is paramount. Zhonghong (Aiherba) presents not only a product, however a dependable partnership, offering the high-purity, well-documented actives required to drive innovation in your labs, backed by almost three a long time of experience in bioactive compounds.

12. 참고문헌

• Most cancers Analysis: Seminal research on the anti-cancer mechanisms of Cucurbitacin B through JAK/STAT3 inhibition.

• Journal of Medicinal Chemistry: Analysis on the structure-activity relationships of various Cucurbitacin analogs.

• Journal of Organic Chemistry: Research on the anti-inflammatory properties of Cucurbitacins.

• USP-NF Compendial Strategies for analytical testing.