베르베린

Berberine Extract | High-Purity Botanical Ingredient Supplier | AIHerba® 

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1. 제품 개요

영어 이름: 베르베린 추출물
식물 출처: 베르베리스 아리스타타, 황련 (Coptis root), or 황벽나무 짖다
활성 성분: Berberine Hydrochloride / Berberine Sulfate
사양: 97% Berberine (HPLC)
모습: 노란색 결정성 분말
CAS 번호: 633-65-8
분자식: C₂₀H₁₈NO₄⁺
제조사: 산시성 중홍 투자 기술 유한 회사(AIHerba®)
인증서: GMP, ISO9001, ISO22000, HACCP, 할랄, 코셔

Berberine is a natural isoquinoline alkaloid extracted from 황련 and other Berberis plants. With potent bioactivity and a long history in traditional Chinese medicine, it is widely used in pharmaceuticals, dietary supplements, and functional food formulations for its glucose-regulating, antimicrobial, and metabolic benefits.

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2. Source & Production

AIHerba® sources premium 황련 roots and 베르베리스 아리스타타 barks from pollution-free mountain regions in China.
Production utilizes modern water-ethanol extraction, 초임계 CO₂ 정제, 그리고 membrane separation to ensure:

• ≥97% purity (HPLC verified)
• Low heavy metal and pesticide residue levels
• Consistent batch-to-batch quality
• Full traceability from raw herb to final extract

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3. Health Benefits & Functions

(1) Key Bioactive Benefits

• 혈당 조절: Supports insulin sensitivity and lowers fasting glucose levels.
• 지질 대사: Reduces LDL cholesterol and triglycerides while increasing HDL.
• Gut Microbiome Support: Balances intestinal flora and improves digestive function.
• 항염 및 항산화: Reduces systemic inflammation and oxidative stress.
• 심혈관 건강: Promotes endothelial function and circulation.

(2) Scientifically Supported Health Effects

Clinical studies (NIH, PubMed) have shown berberine’s comparable effects to metformin in managing Type 2 diabetes and metabolic syndrome.

• NIH Study on Berberine & Glucose Control
• FDA Reference on Herbal Alkaloids

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4. 전통적인 응용 프로그램

수세기 동안 사용됨 전통 중의학(TCM) as “Huang Lian,” berberine was prescribed to treat gastrointestinal infections, fever, and inflammation. In Ayurveda, 베르베리스 아리스타타 (Tree Turmeric) was known for its cleansing and antimicrobial effects.

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5. 권장 복용량 및 사용법

애플리케이션	일반적인 복용량	사용 양식
건강 보조 식품	500~1500mg/일	Capsules, Tablets, Powders
기능성 음료	1회 제공량당 100~300mg	Dissolved or mixed in drink bases
제약 제형	맞춤형	Per regulatory and formulation requirements

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6. Best Formulation Combinations

Berberine is often combined with:

• Milk Thistle Extract (Silymarin): Enhances liver detoxification.
• Alpha Lipoic Acid: Boosts glucose metabolism.
• Cinnamon Extract: Improves insulin sensitivity.
• Probiotics: Supports microbiota balance and absorption efficiency.

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7. Safety & Precautions

• Avoid during pregnancy or lactation without medical supervision.
• May interact with diabetic medications—consult a physician before use.
• 직사광선과 습기를 피해 서늘하고 건조한 곳에 보관하세요.

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8. Technical Specifications (COA Summary)

범주	목	사양	시험 방법
모습	노란색 결정성 분말	준수합니다	시각적
Assay (Berberine)	≥97.0%	HPLC
건조 감량	≤5.0%	105°C, 2h
회분 함량	≤2.0%	중량 측정
용매 잔류물	≤5000ppm	GC

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살충제 잔류물 검사

목	한계(ppm)	방법
디디티	<0.05	GC-ECD
비에이치씨	<0.05	GC-ECD
파라티온	<0.05	GC-MS
카르보푸란	<0.05	LC-MS/MS
클로르피리포스	<0.05	GC-MS

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중금속 테스트

금속	한계	방법
납(Pb)	≤3.0mg/kg	ICP-MS
비소(As)	≤2.0mg/kg	ICP-MS
수은(Hg)	≤0.1mg/kg	ICP-MS
카드뮴(Cd)	≤1.0mg/kg	ICP-MS

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미생물학 검사

매개변수	한계	방법
총 플레이트 수	≤1000 CFU/g	USP <61>
효모 및 곰팡이	≤100 CFU/g	USP <61>
대장균	부정적인	USP <62>
살모넬라균	부정적인	USP <62>
황색포도상구균	부정적인	USP <62>

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9. 제조 공정

1. 원자재 선택 →
2. Crushing & Pre-treatment →
3. 물-에탄올 추출 →
4. 여과 및 농축 →
5. Purification (Membrane & Chromatography) →
6. Drying (Spray or Vacuum Drying) →
7. 분쇄 및 체질 →
8. Quality Inspection & Packaging

All steps follow GMP, ISO 및 HACCP standards with full traceability.

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10. 보관, 유통기한 및 포장

• 저장: Store below 25°C, in a tightly sealed container, protected from light and humidity.
• 유통기한: 생산일로부터 24개월.
• 포장: 25 kg/drum (inner double PE bag + outer fiber drum).
• 샘플: Free 20–50 g samples available upon request.
• 최소주문수량: 1 kg (for trial order).

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11. Logistics & Delivery

• 리드타임: 3–7 working days for standard specifications.
• 배송 방법: DHL, FedEx, UPS, or air/sea freight.
• 세관 서류: COA, MSDS, TDS, Non-GMO statement, and Origin Certificate available.

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12. Application Industries

산업	응용 프로그램
건강기능식품	Blood sugar control, lipid management supplements
제약품	Metabolic and anti-inflammatory formulations
기능성 식품	Metabolic health beverages, herbal tonics
화장품	Antibacterial and anti-inflammatory skin formulations
Veterinary & Feed Additives	Natural antimicrobial ingredient

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13. Why Choose AIHerba®?

✅ Professional Factory: 위에 28년 of production experience in botanical extracts.
✅ 인증: GMP, ISO9001, ISO22000, HALAL, KOSHER.
✅ OEM/ODM Solutions: Custom formulations for global brands.
✅ Global Clients: Trusted by 1,000+ health and cosmetic companies.
✅ 전체 추적성: Raw material to final batch with transparent quality control.

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14. 자주 묻는 질문(FAQ)

Q1: Is berberine water-soluble?
A1: Berberine hydrochloride is slightly soluble in water but dissolves better in ethanol and methanol.

Q2: Can I get customized specifications (e.g., 85% Berberine)?
A2: Yes. We provide tailored purity levels and formulation bases according to client needs.

Q3: What is the lead time for bulk orders?
A3: Typically 5–10 days depending on quantity and specification.

Q4: Can AIHerba provide third-party testing reports?
A4: Yes. We can provide SGS, Eurofins, or Intertek reports upon request.

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15. 참고문헌

1. Yin, J. et al. “Efficacy of Berberine in Type 2 Diabetes Mellitus: A Meta-analysis.” 대사 (2008). PubMed Link
2. NIH: Berberine — Herbal Supplement Information. NIH.gov
3. FDA Botanical Drug Development Guidance. FDA.gov

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문의하기
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