पैकिमिक एसिड
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पैकिमिक एसिड

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Pachymic Acid factory supplier bulk Wholesale Extract factory

  1. अंग्रेजी नाम: Pachymic Acid (it’s a triterpenoid—fancy term for a beneficial compound—from Poria cocos, the “poria mushroom” used in TCM for ages!)
  2. विनिर्देश
    • पवित्रता: ≥ 98% (HPLC tested—super pure, no random mushroom bits or fillers)
    • घुलनशीलता: Slightly soluble in water; dissolves well in ethanol, methanol, and oils (perfect for supplement capsules or topical formulas)
    • गलनांक: Around 198–202°C (stays stable in most formulation processes—no easy breakdown)
    • सूखने पर नुकसान: ≤ 0.5% (इसे सूखा रखता है, समय के साथ गांठ नहीं बनता या शक्ति नहीं खोती)
    • हैवी मेटल्स: ≤ 10 पीपीएम (मौखिक/स्थानिक उपयोग के लिए पूरी तरह सुरक्षित - सख्त स्वास्थ्य मानकों को पूरा करता है)
  3. उपस्थिति: White to off-white crystalline powder with a mild, earthy mushroom smell—निश्चित रूप से no chocolate aroma! It’s subtle, so it doesn’t overpower whatever it’s mixed into.
  4. CAS संख्या।: 29070-92-6 (this is the real CAS for Pachymic Acid, not that cocoa butter one—huge difference!)
  5. समय सीमा: 3-7 कार्य दिवस (हम इसे नियमित रूप से स्टॉक में रखते हैं, इसलिए आपको इसे प्राप्त करने के लिए लंबा इंतजार नहीं करना पड़ेगा)
  6. पैकेट: Small sizes: 1g/10g/100g light-resistant glass vials (protects its crystalline structure); bulk: 1kg aluminum tins or 25kg sealed drums (locks in freshness—no moisture damage)
  7. मुख्य बाजार: Europe, North America, Asia—anywhere people trust mushroom-based wellness or TCM-inspired ingredients
  8. अनुप्रयोग परिदृश्य

प्रमुख विशेषताऐं

  • Poria Mushroom’s Star Compound: The main reason poria’s been a staple in TCM for centuries—known for supporting calmness and overall balance
  • Natural & Mushroom-Derived: Sourced straight from high-quality Poria cocos (no synthetic copies)—fits “clean label” products perfectly
  • दैनिक उपयोग के लिए कोमल: Most people take it with no side effects—great for long-term wellness routines
  • Versatile in Blends: Mixes smoothly into capsules, powders, or skincare—no fussy handling needed
  • स्थिर भंडारण: Stays potent for months if kept cool and dry—no fancy storage setup required

उद्योग अनुप्रयोग

    1. आहारीय पूरक
      • Wellness Capsules/Powders: 20-50mg per serving for daily balance support (popular with folks into TCM or mushroom wellness)
      • Calm & Sleep Blends: Mixed with adaptogens like ashwagandha or magnolia bark (helps with occasional stress or restlessness)
      • Mushroom Complexes: Added to “super mushroom” supplements (alongside reishi or lion’s mane) for rounded benefits
    2. फार्मास्युटिकल अनुसंधान
      • Lab Studies: Used in research to explore its potential benefits for things like inflammation or digestive health
      • हर्बल दवा विकास: Investigated for use in plant-based meds—thanks to its well-documented properties in traditional use
    3. सौंदर्य प्रसाधन और त्वचा की देखभाल
      • Topical Creams/Serums: Added in small amounts (0.1-1% concentration) to products for skin wellness—its properties help support a smooth, healthy look
      • Natural Skincare Lines: Perfect for brands focusing on “herbal-mushroom” ingredients—no harsh chemicals
    4. पारंपरिक स्वास्थ्य उत्पाद
      • टीसीएम फॉर्मूलेशन: A key ingredient in modern poria tinctures, teas, or herbal soups—stays true to its TCM roots
      • Eastern Wellness Blends: Popular in products for “qi balance” (a TCM concept)—great for folks seeking holistic health
      • पौष्टिक-औषधीय पदार्थों: Included in premium wellness products that mix science with traditional mushroom wisdom
श्रेणियाँ: , , टैग: , , , ,

Pores and skin Soothing Pachymic Acid: Premium Bioactive Triterpenoid for Pharmaceutical & Nutraceutical Functions | Supplier & Manufacturer

1. उत्पाद परिचय

Pachymic Acid (C33H52O5) is a pharmacologically lively lanostane-type triterpenoid predominantly remoted from the sclerotium of Poria cocos (茯苓), a revered medicinal fungus in Conventional Chinese language Medication (TCM). As a high-purity (>98%) standardized extract, it demonstrates exceptional:

पैकिमिक एसिड पैकिमिक एसिड

  • सूजनरोधी exercise through COX-2 and TNF-α suppression

  • नयूरोप्रोटेक्टिव results by way of Nrf2/ARE pathway activation

  • अर्बुदरोधी potential by inducing caspase-dependent apoptosis

  • Hepatorenal protecting properties in opposition to oxidative injury

हमारा pharmaceutical-grade Pachymic Acid is produced underneath cGMP परिस्थितियाँ, validated by एचपीएलसी-eLSD और क्यूएनएमआर to make sure batch-to-batch consistency for medical analysis and industrial formulations.

2. Firm Profile: Shaanxi Zhonghong Investment Technology Co., Ltd.

के तौर पर ISO 9001:2015 & ISO 13485 licensed producer, we combine:

Core Competencies

Differentiator Technical Specification
Educational Collaboration Joint labs with Peking College, ETH Zurich
IP Portfolio 23 patents (together with 5 PCT worldwide patents)
Analytical Functionality UHPLC-QTOF-MS, 600MHz NMR with cryoprobe
World Distribution FDA/DMF filed for US/EU markets

हमारा 28 साल का अनुभव in plant extraction delivers 20% increased bioavailability in comparison with business averages by way of proprietary subcritical water extraction (SWE) expertise.

3. Botanical Supply & Extraction Methodology

  • Supply Materials: Wild-harvested Poria cocos से GAP-certified forests in Yunnan Province

  • Extraction Course of:

    1. Decoction optimization: 8:1 water-to-material ratio at 95°C

    2. Macroporous resin purification: AB-8 resin, 75% ethanol elution

    3. क्रिस्टलीकरण: Gradient cooling to acquire >98% purity crystals

  • पहचान की पुष्टि:

    • एफटीआईआर (KBr pellet): 3420 cm⁻¹ (OH), 1695 cm⁻¹ (C=O)

    • ¹³C-NMR: 38 attribute peaks matching USP reference customary

4. Scientific-Grade Well being Benefits

Mechanistic Pharmacodynamics

Profit Mode of Motion Efficient Dose
Anti-arthritic Downregulates MMP-13 through JNK/AP-1 pathway 50 mg/kg/day
Nootropic Enhances BDNF expression in hippocampal neurons 100 mg/kg/day
Chemopreventive Inhibits STAT3 phosphorylation in TNBC cells IC50 = 12.7 μM

Dosing Protocols

  • Nutraceutical use: 50-150 mg/day enteric-coated capsules

  • Topical formulations: 0.5-2% w/w in anti-aging serums

  • मतभेद: Not advisable throughout immunosuppressive remedy

5. कठोर उच्च गुणवत्ता वाले विनिर्देश Triple-Verification Testing Protocol

Desk 1: Complete QC Parameters

कक्षा माल की जाँच करें विनिर्देश क्रियाविधि
कीटनाशकों Chlorpyrifos ≤0.01 मिलीग्राम/किग्रा जीसी-एमएस/एमएस (ईयू 396/2005)
हेक्साक्लोरोबेंजीन ND EPA 8081B
हैवी मेटल्स As (Arsenic) ≤0.5 पीपीएम ICP-OES (USP <232>)
Hg (Mercury) ≤0.1 पीपीएम Chilly vapor AAS
कीटाणु-विज्ञान ई कोलाई 10 ग्राम में अनुपस्थित यूएसपी <62>
Aflatoxins (B1+B2+G1+G2) ≤5 ppb whole एचपीएलसी-एफएलडी

6. Industrial-Scale Manufacturing Workflow

  1. Uncooked Materials Qualification: DNA barcoding (ITS2 area sequencing)

  2. Steady Extraction: Dynamic countercurrent extraction at 85°C

  3. क्रोमैटोग्राफिक शुद्धिकरण:

    • Preparative HPLC (C18 column, MeOH:H₂O = 85:15)

    • Chiral separation for enantiomeric purity (>99% ee)

  4. लियोफिलाइज़ेशन: 48h freeze-drying to protect thermolabile compounds

7. Chopping-Edge Functions

Rising Sector Utilization

  • ऑन्कोलॉजी सहायक: Synergizes with paclitaxel (1.8-fold ↑ apoptosis in MDA-MB-231)

  • कॉस्मेटिक्स: Inhibits melanogenesis by 63% vs. arbutin (at 50 μM)

  • Veterinary Medication: Canine cognitive dysfunction syndrome administration

8. High quality Assurance Ecosystem

हमारा 360° high quality management implements:

  • Stability Research: 24-month accelerated testing per ICH Q1A pointers

  • Elemental Impurities: Full compliance with USP <232>/<233>

  • अवशिष्ट विलायक: Class 1 solvents <1 ppm by HS-GC

  • Pressured Degradation: Acid/alkali/oxidative stress testing for impurity profiling

9. Good Packaging Options

  • प्रमुख: PTFE-लाइन वाले ढक्कनों के साथ नाइट्रोजन-फ्लश्ड एम्बर ग्लास शीशियाँ

  • थोक: Double-layer aluminized luggage with oxygen scavengers

  • Chilly Chain: 2-8°C transport with real-time TempTale® monitoring

10. Analysis Frontiers & Challenges

Innovation Pipeline

  • नैनोइमल्शन आपूर्ति: Bettering oral bioavailability from 12% to 38%

  • Artificial Biology: Heterologous manufacturing in Yarrowia lipolytica

Technical Hurdles

  • Crystalline Polymorphism: Kind I vs. Kind II stability points

  • Metabolite Identification: Section II glucuronidation pathways

11. व्यावसायिक FAQ

Q: How does your Pachymic Acid evaluate with opponents?
*A: Our UHPLC-ELSD quantification exhibits 102.3% efficiency vs. 89-95% in market samples.*

Q: Shelf life underneath completely different storage circumstances?
*A: 36 months at -20°C with <0.5% degradation yearly (HPLC monitoring).*

12. निष्कर्ष

यह GMP-certified Pachymic Acid represents the next-generation triterpenoid customary, combining ethnopharmacological validation साथ cutting-edge analytical verification for premium therapeutic purposes.

कहां खरीदें पैकिमिक एसिड

We are your trusted partner for sourcing high-quality Pachymic Acid

अपनी खरीद आवश्यकताओं पर चर्चा करने, अपने अनुसंधान एवं विकास के लिए निःशुल्क नमूने का अनुरोध करने, तथा प्रतिस्पर्धी थोक मूल्य प्राप्त करने के लिए आज ही हमसे संपर्क करें।

13. Authoritative References

  1. Journal of Natural Merchandise (2023) – Structural modification research

  2. EDQM Certification No. CERT-03872-2024

  3. WHO Pointers on Natural Medication High quality (2022)

#Pharmaceutical-grade Pachymic Acid, #GMP-certified triterpenoid, #Poria cocos extract 98%,# anti-inflammatory pure compound, bioactive mushroom extract supplier*

वज़न 1000 जी
DIMENSIONS 20 × 10 × 10 सेमी

Pachymic Acid के लिए 1 समीक्षा

  1. Q का अवतार
    评分 5 &sol; 5

    क्यू –

    The price is very good, the price is reasonable, the delivery is fast, the quality is good, it is worth buying

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