Gastrodia Phenolic Compounds

Gastrodia Phenolic Compounds for Health Products – Wholesale Herbal Extract Manufacturer

1. English Name: Gastrodia Phenolic Compounds

2. Specification

• • Total Phenolic Content: ≥ 15 – 30% (Folin – Ciocalteu method)

• • Major Components: p – Hydroxybenzaldehyde ≥ 5% (HPLC), p – Hydroxybenzoic acid ≥ 3% (HPLC), vanillic acid ≥ 2% (HPLC)

• • Water – soluble Powder: Solubility ≥ 90% in water, moisture ≤ 5%

3. Appearance

• • Light brown to yellowish – brown fine powder, mild herbal odor

4. CAS NO.

• • p – Hydroxybenzaldehyde: 123 – 08 – 0

• • p – Hydroxybenzoic acid: 99 – 96 – 7

• • vanillic acid: 121 – 34 – 6

5. Lead time: 3 – 7 Working Days

6. Package

• • 1 kg/bag (aluminum foil bag), 25 kg/drum (double – layer PE bag inside cardboard drum)

7. Main Market: Asia (China, Japan, South Korea), North America, Europe

8. Application Scenarios

• Molecular Structure: Composed of various phenolic acids and aldehydes with a benzene ring and hydroxyl groups

• Solubility: Soluble in water, ethanol, and methanol; water – soluble formulations are ideal for beverage and pharmaceutical applications

• Key Features

• • Antioxidant: Scavenges free radicals such as DPPH and hydroxyl radicals, with an ORAC (Oxygen Radical Absorbance Capacity) value of 2000 – 3500 μmol Trolox equivalents/g.

• • Anti – inflammatory: Inhibits the production of pro – inflammatory cytokines like TNF – α and IL – 6.

• • Neuroprotective: Protects neurons from oxidative stress and apoptosis, potentially beneficial for neurodegenerative diseases.

• • Antimicrobial: Exhibits inhibitory activity against certain bacteria and fungi, such as Staphylococcus aureus and Candida albicans.

• Neurological Disorder Treatment:

• • Investigated for the treatment of stroke and epilepsy, as the neuroprotective properties help reduce brain damage and prevent seizure recurrence.

• • Used in combination with other drugs to enhance the treatment effect of Alzheimer’s disease by reducing oxidative stress in the brain.

• Anti – inflammatory Formulations:

• • Incorporated into topical creams and ointments to relieve skin inflammation, such as eczema and dermatitis.

• Antioxidant Supplements:

• • Capsules or tablets containing 200 – 500 mg of phenolic compounds in Gastrodia, marketed for general health maintenance and anti – aging, often combined with other antioxidants like vitamin C and E.

• Brain Health Formulas:

• • Added to nootropic supplements to support cognitive function, memory, and focus.

• Anti – aging Products:

• • Serums and moisturizers (2 – 5% concentration) to protect skin from UV – induced damage, reduce the appearance of fine lines and wrinkles, and promote skin elasticity.

• Antibacterial Skincare:

• • Used in facial cleansers and acne treatments to inhibit the growth of acne – causing bacteria.

• Antioxidant – Rich Beverages:

• • Added to fruit juices, tea – based drinks, and energy drinks at 0.5 – 1% concentration to enhance the antioxidant capacity and extend shelf life.

• Fortified Foods:

• • Incorporated into baked goods, cereals, and snacks to increase their nutritional value and provide health – promoting benefits.

• High – Performance Liquid Chromatography (HPLC):

• • Column: C18 (250 × 4.6 mm, 5 μm), Mobile Phase: Acetonitrile – 0.1% phosphoric acid (gradient elution), Flow Rate: 1.0 mL/min, Detection Wavelength: 280 nm for p – Hydroxybenzaldehyde, 254 nm for p – Hydroxybenzoic acid, and 325 nm for vanillic acid.

• Folin – Ciocalteu Assay:

• • A colorimetric method to determine the total phenolic content, measuring absorbance at 765 nm.

• Mass Spectrometry (MS):

• • Used in combination with HPLC (HPLC – MS) to confirm the molecular structure and identify trace phenolic compounds.

• Natural Source: Extracted from the rhizomes of Gastrodia elata Blume, a traditional Chinese medicinal herb.

• Multi – functional Benefits: Their diverse bioactivities make them suitable for various applications from medicine to consumer products.

• Traditional Use Validation: With a long history of use in traditional Chinese medicine, it provides a reliable foundation for modern applications.

• China NMPA: Approved as a dietary supplement ingredient and used in traditional Chinese medicine formulations.

• US FDA: Regulated as a dietary ingredient when used in supplements, subject to Good Manufacturing Practice (GMP) requirements.

• EU Cosmetic Regulation: Allowed as a cosmetic ingredient, with restrictions on maximum concentration in different product types.