Ácido paquímico
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Ácido paquímico

Valorado 5.00 sobre 5 basado en 1 puntuación de cliente
(1 valoración de cliente)

Pachymic Acid factory supplier bulk Wholesale Extract factory

  1. Nombre en inglés: Pachymic Acid (it’s a triterpenoid—fancy term for a beneficial compound—from Poria cocos, the “poria mushroom” used in TCM for ages!)
  2. Especificación
    • Pureza: ≥ 98% (HPLC tested—super pure, no random mushroom bits or fillers)
    • Solubilidad: Slightly soluble in water; dissolves well in ethanol, methanol, and oils (perfect for supplement capsules or topical formulas)
    • Punto de fusión: Around 198–202°C (stays stable in most formulation processes—no easy breakdown)
    • Pérdida por secado: ≤ 0,5% (lo mantiene seco, sin aglutinarse ni perder potencia con el tiempo)
    • Metales pesados: ≤ 10 ppm (totalmente seguro para uso oral/tópico; cumple con estrictos estándares de bienestar)
  3. Apariencia: White to off-white crystalline powder with a mild, earthy mushroom smell—definitivamente no chocolate aroma! It’s subtle, so it doesn’t overpower whatever it’s mixed into.
  4. N.º CAS.: 29070-92-6 (this is the real CAS for Pachymic Acid, not that cocoa butter one—huge difference!)
  5. Plazo de entrega:3-7 días laborables (lo mantenemos en stock regularmente, por lo que no esperará mucho para recibirlo)
  6. Paquete: Small sizes: 1g/10g/100g light-resistant glass vials (protects its crystalline structure); bulk: 1kg aluminum tins or 25kg sealed drums (locks in freshness—no moisture damage)
  7. Mercado principal: Europe, North America, Asia—anywhere people trust mushroom-based wellness or TCM-inspired ingredients
  8. Escenarios de aplicación

Características principales

  • Poria Mushroom’s Star Compound: The main reason poria’s been a staple in TCM for centuries—known for supporting calmness and overall balance
  • Natural & Mushroom-Derived: Sourced straight from high-quality Poria cocos (no synthetic copies)—fits “clean label” products perfectly
  • Suave para uso diario: Most people take it with no side effects—great for long-term wellness routines
  • Versatile in Blends: Mixes smoothly into capsules, powders, or skincare—no fussy handling needed
  • Almacenamiento estable: Stays potent for months if kept cool and dry—no fancy storage setup required

Aplicaciones industriales

    1. Suplementos dietéticos
      • Wellness Capsules/Powders: 20-50mg per serving for daily balance support (popular with folks into TCM or mushroom wellness)
      • Calm & Sleep Blends: Mixed with adaptogens like ashwagandha or magnolia bark (helps with occasional stress or restlessness)
      • Mushroom Complexes: Added to “super mushroom” supplements (alongside reishi or lion’s mane) for rounded benefits
    2. Investigación farmacéutica
      • Lab Studies: Used in research to explore its potential benefits for things like inflammation or digestive health
      • Desarrollo de fármacos a base de hierbas: Investigated for use in plant-based meds—thanks to its well-documented properties in traditional use
    3. Cosméticos y cuidado de la piel
      • Topical Creams/Serums: Added in small amounts (0.1-1% concentration) to products for skin wellness—its properties help support a smooth, healthy look
      • Natural Skincare Lines: Perfect for brands focusing on “herbal-mushroom” ingredients—no harsh chemicals
    4. Productos tradicionales de bienestar
      • Formulaciones de la MTC: A key ingredient in modern poria tinctures, teas, or herbal soups—stays true to its TCM roots
      • Mezclas de bienestar oriental: Popular in products for “qi balance” (a TCM concept)—great for folks seeking holistic health
      • Nutracéuticos: Included in premium wellness products that mix science with traditional mushroom wisdom
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Pores and skin Soothing Pachymic Acid: Premium Bioactive Triterpenoid for Pharmaceutical & Nutraceutical Functions | Supplier & Manufacturer

1. Introducción del producto

Pachymic Acid (C33H52O5) is a pharmacologically lively lanostane-type triterpenoid predominantly remoted from the sclerotium of Poria cocos (茯苓), a revered medicinal fungus in Conventional Chinese language Medication (TCM). As a high-purity (>98%) standardized extract, it demonstrates exceptional:

Ácido paquímico Ácido paquímico

  • Antiinflamatorio exercise through COX-2 and TNF-α suppression

  • Neuroprotector results by way of Nrf2/ARE pathway activation

  • Antitumoral potential by inducing caspase-dependent apoptosis

  • Hepatorenal protecting properties in opposition to oxidative injury

Nuestro pharmaceutical-grade Pachymic Acid is produced underneath cGMP circumstances, validated by HPLC-ELSD y qNMR to make sure batch-to-batch consistency for medical analysis and industrial formulations.

2. Firm Profile: Shaanxi Zhonghong Investment Technology Co., Ltd.

Como un ISO 9001:2015 & ISO 13485 licensed producer, we combine:

Competencias básicas

Differentiator Especificación técnica
Educational Collaboration Joint labs with Peking College, ETH Zurich
Cartera de propiedad intelectual 23 patents (together with 5 PCT worldwide patents)
Analytical Functionality UHPLC-QTOF-MS, 600MHz NMR with cryoprobe
World Distribution FDA/DMF filed for US/EU markets

Nuestro 28 años de experiencia in plant extraction delivers 20% increased bioavailability in comparison with business averages by way of proprietary subcritical water extraction (SWE) expertise.

3. Botanical Supply & Extraction Methodology

  • Supply Materials: Wild-harvested Poria cocos de GAP-certified forests in Yunnan Province

  • Extraction Course of:

    1. Decoction optimization: 8:1 water-to-material ratio at 95°C

    2. Macroporous resin purification: AB-8 resin, 75% ethanol elution

    3. Cristalización: Gradient cooling to acquire >98% purity crystals

  • Afirmación de identificación:

    • FTIR (KBr pellet): 3420 cm⁻¹ (OH), 1695 cm⁻¹ (C=O)

    • ¹³C-NMR: 38 attribute peaks matching USP reference customary

4. Scientific-Grade Well being Benefits

Farmacodinámica mecanicista

Ganancia Mode of Motion Efficient Dose
Anti-arthritic Downregulates MMP-13 through JNK/AP-1 pathway 50 mg/kg/day
Nootropic Enhances BDNF expression in hippocampal neurons 100 mg/kg/day
Chemopreventive Inhibits STAT3 phosphorylation in TNBC cells IC50 = 12.7 μM

Dosing Protocols

  • Nutraceutical use: 50-150 mg/day enteric-coated capsules

  • Formulaciones tópicas: 0.5-2% w/w in anti-aging serums

  • Contraindicaciones: Not advisable throughout immunosuppressive remedy

5. Especificaciones rigurosas de alta calidad Triple-Verification Testing Protocol

Desk 1: Complete QC Parameters

Clase Verificar mercancía Especificación Metodología
pesticidas Clorpirifos ≤0,01 mg/kg GC-MS/MS (UE 396/2005)
Hexaclorobenceno DAKOTA DEL NORTE EPA 8081B
Metales pesados As (Arsenic) ≤0,5 ppm ICP-OES (USP <232>)
Hg (Mercury) ≤0,1 ppm Chilly vapor AAS
Microbiología E. coli Ausente en 10g USP <62>
Aflatoxins (B1+B2+G1+G2) ≤5 ppb whole HPLC-FLD

6. Industrial-Scale Manufacturing Workflow

  1. Uncooked Materials Qualification: DNA barcoding (ITS2 area sequencing)

  2. Steady Extraction: Dynamic countercurrent extraction at 85°C

  3. Purificación cromatográfica:

    • Preparative HPLC (C18 column, MeOH:H₂O = 85:15)

    • Chiral separation for enantiomeric purity (>99% ee)

  4. Liofilización: 48h freeze-drying to protect thermolabile compounds

7. Chopping-Edge Functions

Rising Sector Utilization

  • Adyuvantes oncológicos: Synergizes with paclitaxel (1.8-fold ↑ apoptosis in MDA-MB-231)

  • Cosmecéuticos: Inhibits melanogenesis by 63% vs. arbutin (at 50 μM)

  • Veterinary Medication: Canine cognitive dysfunction syndrome administration

8. High quality Assurance Ecosystem

Nuestro 360° high quality management implementos:

  • Investigación de estabilidad: 24-month accelerated testing per ICH Q1A pointers

  • Impurezas elementales: Full compliance with USP <232>/<233>

  • Disolventes residuales: Class 1 solvents <1 ppm by HS-GC

  • Pressured Degradation: Acid/alkali/oxidative stress testing for impurity profiling

9. Good Packaging Options

  • ImportanteViales de vidrio ámbar irrigados con nitrógeno y tapas revestidas de PTFE.

  • A granel: Double-layer aluminized luggage with oxygen scavengers

  • Chilly Chain: 2-8°C transport with real-time TempTale® monitoring

10. Analysis Frontiers & Challenges

Canal de innovación

  • Suministro de nanoemulsiones: Bettering oral bioavailability from 12% to 38%

  • Artificial Biology: Heterologous manufacturing in Yarrowia lipolytica

Obstáculos técnicos

  • Crystalline Polymorphism: Kind I vs. Kind II stability points

  • Identificación de metabolitos: Section II glucuronidation pathways

11. Professional FAQ

Q: How does your Pachymic Acid evaluate with opponents?
*A: Our UHPLC-ELSD quantification exhibits 102.3% efficiency vs. 89-95% in market samples.*

Q: Shelf life underneath completely different storage circumstances?
*A: 36 months at -20°C with <0.5% degradation yearly (HPLC monitoring).*

12. Conclusión

Este GMP-certified Pachymic Acid represents the next-generation triterpenoid customary, combinando ethnopharmacological validation con cutting-edge analytical verification for premium therapeutic purposes.

Dónde comprar Ácido paquímico

We are your trusted partner for sourcing high-quality Pachymic Acid

Contáctenos hoy para discutir sus necesidades de adquisición, solicitar una muestra gratuita para su I+D y obtener un precio mayorista competitivo.

13. Referencias autorizadas

  1. Revista de Mercancía Natural (2023) – Structural modification research

  2. EDQM Certification No. CERT-03872-2024

  3. WHO Pointers on Natural Medication High quality (2022)

#Pharmaceutical-grade Pachymic Acid, #GMP-certified triterpenoid, #Poria cocos extract 98%,# anti-inflammatory pure compound, bioactive mushroom extract supplier*

Peso 1000 gramo
Dimensiones 20 × 10 × 10 centímetro

1 valoración en Pachymic Acid

  1. Avatar De Q
    评分 5 &sol; 5

    Q –

    The price is very good, the price is reasonable, the delivery is fast, the quality is good, it is worth buying

Solo los usuarios registrados que hayan comprado este producto pueden hacer una valoración.

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